• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2000.04a
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• pp.184-188
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• 2000

본 연구의 목표는 감성평가를 위한 실험에서 생성되는 생리신호 및 분석결과와 실험에 관한 각종 정보를 데이터베이스화 하는 것이다. 이를 통해 각종 반복되는 실험 결과의 수집과 분석에 확장성을 도모할 수 있고 실험결과를 지표화 함으로 감성지표를 구축하는데 이용할 수 있다. 그리고 실험정보 또한 데이터베이스화 함으로 실험에 따른 표준화 및 실험의 능률을 높일 수 있고, 감성평가를 위한 모든 기반데이타 및 실험데이타를 구축함으로써 분석시스템 및 측정 시스템의 개발에 적용할 수 있을 것이다.

• Journal of Microbiology and Biotechnology
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• v.16 no.11
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• pp.1661-1677
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• 2006

Rhizobium and related genera are soil bacteria with great metabolic plasticity. These microorganisms survive in many different environments and are capable of eliciting the formation of nitrogen-fixing nodules on legumes. The successful establishment of symbiosis is precisely regulated and requires a series of signal exchanges between the two partners. Quorum sensing (QS) is a prevalent form of population density-dependent gene regulation. Recently, increasing evidence indicates that rhizobial quorum sensing provides a pervasive regulatory network, which plays a more generalized role in the physiological activity of free-living rhizobia, as well as during symbiosis. Several rhizobia utilize multiple, overlapping quorum sensing systems to regulate diverse properties, including conjugal transfer and copy number control of plasmids, exopolysaccharide biosynthesis, rhizosphere-related functions, and cell growth. Genomic and proteomic analyses have begun to reveal the wide range of functions under quorum-sensing control.

• Journal of Applied Biological Chemistry
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• v.50 no.2
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• pp.58-62
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• 2007

Identification of Dual-specificity protein phosphatase (DSP) substrates is essential in revealing physiological roles of DSPs. We isolated VHZ-interacting proteins from extracts of 293T cells overexpressing a VHZ (C95S, D65A) mutant known to be substrate- trapping mutant. Analysis of specific proteins bound to VHZ by 2D gel electrophoresis and mass spectroscopy revealed that these proteins contained Chaperonin containing TCP1, Type II phosphatidylinositol phosphate kinase ${\gamma}$, Intraflagellar transport 80 homolog, and Kinesin superfamily protein 1B. VHZ-interacting proteins showed that VHZ is involved in many important cellular signal pathways such as protein folding, molecular transportation, and tumor suppression.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.05
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• pp.426-429
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• 1997

This paper describes the relationship among physiological, behavioral signal, and subjective evaluation depending on arousal level. Nz and reaction time hall similar pattern with KSS level, but eyeblink rate was different from these two parameters. Eyeblink rate increased slowly from KSS level 1 to 5, and had high increasing rate at KSS 7. But it showed steep descent at KSS level 9. From the result of reaction time test, since human performance was decreased rapidly above the KSS level 5, it is desirable to give a subject some stimulus such as sound or aroma to rise arousal level above the KSS level 3.

• Journal of Fisheries and Marine Sciences Education
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• v.19 no.3
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• pp.502-509
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• 2007

This study evaluates thermal comfort by air conditioner temperature raising at the point of time that human body begins to adapt. Thermal comfort according to change of time enters by uncomfortable area gradually at general cold room temperature that magnetic pole is in human body. However, can know that keep continuous thermal comfort in case raise temperature in human body adaptation visual point. Experiments were performed in environmental chamber. Subjects were selected 4 men and 4 women whose life cycle were proved that are similar. The subjects stay in the pretesting room during the 30 minutes and enter the testing room under each experiment conditions. During the experiment, brain wave, electrocardiogram, blood pressure and thermal comfort and sensation responses were measured. In this study, physiological and psychological responses correspond under temperature raising at human body adaptation.

• BMB Reports
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• v.35 no.1
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• pp.67-86
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• 2002

Three routes have been identified triggering neuronal death under physiological and pathological conditions. Excess activation of ionotropic glutamate receptors cause influx and accumulation of $Ca^{2+}$ and $Na^+$ that result in rapid swelling and subsequent neuronal death within a few hours. The second route is caused by oxidative stress due to accumulation of reactive oxygen and nitrogen species. Apoptosis or programmed cell death that often occurs during developmental process has been coined as additional route to pathological neuronal death in the mature nervous system. Evidence is being accumulated that excitotoxicity, oxidative stress, and apoptosis propagate through distinctive and mutually exclusive signal transduction pathway and contribute to neuronal loss following hypoxic-ischemic brain injury. Thus, the therapeutic intervention of hypoxic-ischemic neuronal injury should be aimed to prevent excitotoxicity, oxidative stress, and apoptosis in a concerted way.

• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.2
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• pp.195-199
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• 2014

Although the Herba Cirsii is known to posses beneficial health effects, the anti-diabetic effects and the mechanism of action have not been elucidated. In the present study we have shown that Herba Cirsii Extract (HCE) can stimulate glucose uptake in OP9 adipocytes. Unlike insulin, HCE did not stimulate the Ser473 phosphorylation and activation of Akt. The increasing effects of HCE on glucose uptake were inhibited by PD680509 and compound C pretreatment, which means that the glucose uptake effects by HCE were carried out by extracelluar signal-regulated kinase1/2(ERK1/2) and AMP-activated protein kinase (AMPK) activation. Further studies revealed that HCE stimulated glucose transport occurs through a mechanism involving ERK1/2 activation and AMPK activation.

• The Korean Journal of Nuclear Medicine
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• v.38 no.2
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• pp.205-208
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• 2004

The two major classes of magnetic resonance (MR) contrast agents are paramagnetic contrast agents, usually based on chelates of gadolinium generating T1 positive signal enhancement, and super-paramagnetic contrast agents that use mono- or polycrystalline iron oxide to generate strong T2 negative contrast in MR images. These paramagnetic or super-paramagnetic complexes are used to develop new contrast agents that can target the specific molecular marker of the cells or tan be activated to report on the physiological status or metabolic activity of biological systems. In molecular imaging science, MR imaging has emerged as a leading technique because it provides high-resolution three-dimension maps of the living subject. The future of molecular MR imaging is promising as advancements in hardware, contrast agents, and image acquisition methods coalesce to bring high resolution in vivo imaging to the biochemical sciences and to patient care.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.61 no.1
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• pp.55-58
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• 2012

By using EEG and HRV, subjects were estimated on their psychological and physiological reaction when reading psychrometric chart in 7 point century font, in an environmental test room in the condition of temperature 25[$^{\circ}C$], relative humidity 50[RH%], air current speed 0.02[m/sec], giving variation in illuminance to 0.1, 300, 600, 1000, 1300 and 1600[lux]. As a result, it was at 1300[lux] that absolute ${\alpha}$ wave, SMR, SDNN were most vitalized, and also both sides ${\alpha}$ wave asymmetry index, SEF50, HRT, stress and fatigue degree were at the lowest. It was found that a certain illuminance which minimizes psychological stress and fatigue degree while enhancing concentration and task achievement stably does exist.

• Journal of applied mathematics & informatics
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• v.29 no.1_2
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• pp.427-442
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• 2011

Calcium is a vital second messenger for signal transduction in neurons. Calcium plays an important role in almost every part of the human body but in neuronal cytosol, it is of utmost importance. In order to understand the calcium signaling mechanism in a better way a finite element model has been developed to study the flow of calcium in two dimensions with time. This model assumes EBA (Excess Buffering Approximation), incorporating all the important parameters like time, association rate, influx, buffer concentration, diffusion constant etc. Finite element method is used to obtain calcium concentration in two dimensions and numerical integration is used to compute effect of time over 2-D Calcium profile. Comparative study of calcium signaling in two dimensions with time is done with other important physiological parameters. A MATLAB program has been developed for the entire problem and simulated on an x64 machine to compute the numerical results.