• 산업경영시스템학회지
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• 제23권57호
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• pp.1-10
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• 2000

The purpose of this paper is to propose a method of rest to reduce work load of night shift workers for night shift work. The experiment was carried out 10minutes preparing time, 45minutes first work, 10minutes first rest, 45minutes second work, 10minutes second rest between 2 and 4 o'clock that the lowest physiological function of workers. The methods of rest set up as four patterns (1) non-action rest (2) non-action rest + listening music (3) action rest + non-action rest, (4) action rest + non-action rest + listening music. For the measurements of experiment, heart rates(R-R interval), critical flicker fusion frequency(CFF), blood pressure, oral temperature, reaction time and error rates were considered as criteria for work performance. As a result, action rest + non-action rest and action rest + non-action rest + listening music were more effective to reduce work load additional work than non-action rest and non-action rest + listening music.

• 한국통신학회논문지
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• 제21권4호
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• pp.1038-1047
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• 1996

The effect of electromagnetic wave on the biobody is to make a possibility not increasing temperature but also inducing physiological and psychological damage which is head or backbone. Generally a vital function of hean can be estimated by the measureing of Electro Encephalogram(EEG), and achieved a response of a find stimulus which can not be defected a subjective sympton and out of reaction. In this paper, the head can be modeled according to its medium and dervated the equation of SAR distritution, and the head of rabbit is approximately modeled three layers practically and the result of each SAR distribution is illustrated. Measured EEG from the nervous system of rabbit on a plane wave irradiated an be used quantitative analysis for the electrophysiogical effect of the biobody.

• 한국식품영양과학회지
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• 제27권3호
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• pp.441-447
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• 1998

A bacterial strain No. 43 was isolated from soil samples as a levan-assimiating microorganism producing an extracellular levanase and hydrolying levan to levanbiose. According to the taxonomic characteristics of its morphological and physiological properties, the strain was idenified as Pseudomonas sp. No. 43. The optimum culura medium was composed of 10g levan, 5g(NH4)2SO4, 3g NH4Cl, 3g polypepton, 1g K2HPO4, 0.5gMgSO4.7H2O, and 0.2g MnCl2.4H2O per liter. The cultivation for levanase was carried out in pH 7.0 at 4$0^{\circ}C$ for 28hr. The reaction product was a kind of oligosaccharide and it was purified by chilled ethanol precipitation and gel filtration for evalluation of degree of polymerization (DP). The purified product was determined as levanbiose of MW 342 and DP2 by HPLC and FAB-MS.

• International Journal of Oral Biology
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• 제45권2호
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• pp.64-69
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• 2020

Short-chain fatty acids (SCFAs) such as acetate, propionate, and butyrate are secondary metabolites produced by anaerobic fermentation of dietary fibers in the intestine. Intestinal SCFAs exert various beneficial effects on intestinal homeostasis, including energy metabolism, autophagy, cell proliferation, immune reaction, and inflammation, whereas contradictory roles of SCFAs in the oral cavity have been reported. Herein, we found that low and high concentrations of SCFAs induce differential regulation of intracellular Ca²⁺ mobilization and expression of pro-inflammatory cytokines, such as interleukin (IL)-6 and IL-8, respectively, in gingival fibroblast cells. Additionally, cell viability was found to be differentially regulated in response to low and high concentrations of SCFAs. These findings demonstrate that the physiological functions of SCFAs in various cellular responses are more likely dependent on their local concentration.

• 동의생리병리학회지
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• 제23권5호
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• pp.1125-1131
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• 2009

Lophatheri Herba, Patriniae Radix, Alli tuberosi Herba, and Menthae Herba have long been used externally for treatment of injuries or inflammations in Korea. This study was carried out to examine the anti-dandruff effect of the mixture made with equal parts of 70%-ethanol extracts of Lophatheri Herba, Patriniae Radix, Allii tuberosi Herba, and Menthae Herba (LPAM) and of each one above, compared with 1%-zinc pyrithione (Standard) used commercially as anti-dandruff. The results showed the mixture was more effective than each crude drug. The 10%-LPAM produced no toxicity in skin reaction test and eye irritation test, and showed significant antimicrobial activity against Pityrosporum ovale, the major cause of dandruff, and also showed significant anti-dandruff and itch-improvement effects on head skin.

• Archives of Pharmacal Research
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• 제29권3호
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• pp.213-217
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• 2006

The present study was undertaken to test the hypothesis that dietary antioxidants protect DNA damage induced by peroxynitrite, a potent physiological inorganic toxin. The present study showed that dietary antioxidants such as (-)-epigallocatechin gallate, quercerin, rutin, resveratrol, and ursolic acid inhibit single strand breaks in supercoiled plasmid DNA induced by 3-morpholinosydnomine N-ethylcarbamide (SIN-1), a generator of peroxynitrite through the reaction between nitric oxide and superoxide anion. The formation of 8-hydroxy-2'-deoxyguanosine (8-OH-dG) in calf thymus DNA by SIN-1 was also inhibited by dietary antioxidants. When U937 cells were incubated with 1 mM SIN-1 bolus, a significant increase of 8-OH-dG level was observed. However, oxidative DNA damage was significantly lower in the cells pre-treated with dietary antioxidants when cells were exposed to SIN-1.

• 동의생리병리학회지
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• 제20권2호
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• pp.312-319
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• 2006

Lee je-ma emphasis human constitution and write DongYeuSuSebowon(東醫壽世保元). He describe Sasang constitution diseases with Treatise on Febrile Diseases(傷寒論). Exogenous febrile disease(傷寒) is a pyrexia disease. Therefor this paper is focus on the pyrexia at Soyinin(少陰人) among DongYeuSuSebowon. Soyinin(少陰人) is consider that body water loss is more important than fever in pyrexia disease. And body water loss is happens easily at exothermic reaction (sweating, diarrhea) and sequela of Purgative Prescription(瀉下法), Inducing Diaphoresis(發汗法), Diuresis(利小便法).

• 전기학회논문지P
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• 제61권1호
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• pp.55-58
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• 2012

By using EEG and HRV, subjects were estimated on their psychological and physiological reaction when reading psychrometric chart in 7 point century font, in an environmental test room in the condition of temperature 25[$^{\circ}C$], relative humidity 50[RH%], air current speed 0.02[m/sec], giving variation in illuminance to 0.1, 300, 600, 1000, 1300 and 1600[lux]. As a result, it was at 1300[lux] that absolute ${\alpha}$ wave, SMR, SDNN were most vitalized, and also both sides ${\alpha}$ wave asymmetry index, SEF50, HRT, stress and fatigue degree were at the lowest. It was found that a certain illuminance which minimizes psychological stress and fatigue degree while enhancing concentration and task achievement stably does exist.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2008년도 추계학술대회A
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• pp.1669-1673
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• 2008

In this study, we simulated the atrial arrhythmia numerically. By using electro-physiological model of atrial cell from Nygren et al. and applying reaction-diffusion partial differential equation, we simulated electrical conduction in atrium. A 3-D mesh system representing the human atrium was reconstructed from the surface geometry of atrium. We used a stimulus in the form of an archetype around pulmonary vessels in the left atrium to cause the atrial arrhythmia. The septal atrial tarchycardia was developed after the stimulus.

• 대한의생명과학회지
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• 제18권4호
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• pp.420-427
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• 2012

Sprague-Dawley (SD) rats were orally administered with NG-nitro-L-arginine methyl ester (L-NAME), which inhibits or blocks the production of nitric oxide from L-arginine in vascular endothelial cells and vessel tissue. We examined the effects of nitric oxide on some physiological changes such as blood pressure and heart rate, and confirms the apoptosis induced by the suppressed nitric oxide activity in the kidney. This study was performed to investigate correlation between the activities of nitric oxide and apoptosis by immunohistochemical changes of apoptotic control proteins with regulated chronic inhibition of nitric oxide. In the kidney from L-NAME-treated group, immunohistochemical reaction to the antigens of apoptosis inhibiting proteins such as bcl-2 and bcl-xL, exhibited a time-dependent reduction. The expression of apoptosis-inhibiting proteins such as bax and p53 increased expression in proportion to the duration of treatment. The most sensitive apoptosis regulating proteins to L-NAME were p53 in stimulation and bcl-2 in inhibition, respectively.