• The Journal of the Convergence on Culture Technology
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• v.1 no.1
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• pp.37-64
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• 2015

This technical research paper attempts to examine literature therapeutic significance of Sijo. This research analyzes how the therapeutic mechanisms of literature or sentence can be physiologically applied to human nerve system. To study such interactions between therapeutic mechanisms of literature and human physiological mechanisms, diverse on- and offline Sijo activities, such as a Facebook group "Sijoya Nolja", were studied, as well as various publications in literature and medicine. For the three years this research was being conducted, 27 out of 488 Sijo poets debuted through Sinchunmunye, and many have gone professional through various contests. 19 of them became members of Sijo Poet Associations of Korea, with globalization of Sijo in mind. Their aggressive activity proves that the quality of live was elevated through literature therapy. The therapeutic effects are especially dramatic for older authors, and authors with traumatic experience. Through this research, Sijo turned out to be a form of literature with the quickest effect on elevating quality of life. To solve problems such as depression, emotional isolation, and other mental conditions, literature therapy through Sijo should be implemented, and therapeutic approach of literature should be more professionalized.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.6
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• pp.945-960
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• 2011

The BianMaiFa chapter, which is the first chapter of SongBon ShangHanLun, is the scholarly description(專論) of the pulse and pathological mechanism but has not been studied and published yet. This study is about article 1-10 which is the first part of The BianMaiFa chapter. We compared the original texts within the editions, comparing and analyzing the annotations of successive dynastic medical group. The articles of The SongBon ShangHanLun BianMaiFa chapter 1-10 is consisted as is shown: article 1 discriminates pulse by yin-yang and states about the prognosis of disease according to pulse, article 2 states about binding in yin and binding in yang which is from abnormal exuberance of yin and yang, article 3 states about the pulse and pathological mechanism of chills with fever, article 4 states about pathological mechanism and symptom of nutrient and defense through pulse, article 5 distinguishes within binding in yang(陽結), binding in yin(陰結), yang faintness(陽微), yang debilitation(陽衰), blood collapse(亡血) by the pulse which was in article 2 3 4, article 6 7 8 9 10 states states about the shape or pathological mechanism of bound pulse(結脈) skipping pulse(促脈) stirred pulse(動脈) moderate pulse(緩脈) string-like pulse(弦脈) tight pulse(緊脈) drumskin pulse(革脈). Article 4 could be understood that inch pulse is floating and deficient shape and cubit pulse is sunken and weak shape(寸脈浮虛, 尺脈沈弱) related to article 3, article 5 could be understood as binding in yin and yang is aggregation shape related to article 2, yang-qi faintness is floating and debilitation shape, yang-qi debilitation is sunken and faint shape, blood collapse is deficient and stasis shape related to article 3 4.

• Journal of Digital Convergence
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• v.15 no.11
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• pp.591-601
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• 2017

The purpose of this study was to investigate the relationship between psychomotorik and brain function in domestic and foreign literature, and to clarify the mechanism of psychomotorik from the viewpoint of brain science, and to provide the teachers, therapists, The purpose of this study is to provide basic data which can enhance the understanding of the mechanism of psychomotorik. From the viewpoint of brain science, the study of domestic and foreign literature related to the mechanism of psychomotorik and the positive learning environment and various physical experiences in early life through the movement of psychomotorik are very important from the brain physiological point of view. The results of this study showed that the more the children move, the more the learning is improved and the healthy emotional control ability is improved and the brain is more likely to be optimized. Therefore, it is considered that this study, which has been studied through the brain science approach, provided very important basic information to understand the relation between movement of psychomotorik and brain function. In particular, understanding the possibility of optimizing the brain by cultivating a healthy emotional control ability and improving learning as children move more and more is considered to be a necessary process for educating our children well in the future. Until now, research on psychomotorik and brain function was lacking. Through this study, I hope that more people will have an opportunity to expand their understanding of the psychomotorik.

• Journal of Korean Biological Nursing Science
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• v.1 no.1
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• pp.25-41
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• 1999

Physiological activity of osteoblast including bone formation is known to be closely related to the increase of intracellular $Ca^{2+}$ activity($[Ca^{2+}]_i$) in osteoblast. $Ca^{2+}$ is an important intracellular messenger in diverse cellular functions, and regulation of its level is mediated by the transmembrane $Ca^{2+}$ movement via $Ca^{2+}$ channels, $Na^+-Ca^{2+}$ exchange, and by intracellular $Ca^{2+}$ movement through the intracellular stores. The purpose of this study is to investigate how the intracellular $Ca^{2+}$ is regulated in osteoblast-like cells(OLCs) by measuring $Ca^{2+}$ activity with cell imaging technique. OLCs were isolated from femur and tibia of neonatal rats, and cultured for 7 days. Cultured OLCs were loaded with a $Ca^{2+}$-sensitive fluorescent dye, Fura-2, and fluorescence images were monitored with a cooled CCD camera. The images were processed and analyzed with an image analyzing software. The results were as follows. (1) $[Ca^{2+}]_i$ of OLC decreased as the $Ca^{2+}$ concentration in the superfusing Tyrode solution was lowered. When $Na^+$ concentration in the superfusing solution was decreased, $[Ca^{2+}]_i$ increased.. These suggest that $Ca^{2+}$ flux occurs via the $Na^+-Ca^{2+}$ exchange mechanism. (2) When $Na^+$ in the superfusing solution was removed. a transient $Ca^{2+}$, increase($Ca^{2+}$ spike) was occasionally observed. However, $Ca^{2+}$ spike was not observed after adding 1 ${\mu}M$ thapsigargin. This implies that the generation of $Ca^{2+}$ spike is mediated by the release of $Ca^{2+}$ from endoplasmic reticulum(ER). (3) As the $Ca^{2+}$ concentration in the superfusing solution was raised, the frequency of 0mM $Na^+$-induced $Ca^{2+}$ spike increased, suggesting that $Ca^{2+}$-induced $Ca^{2+}$ release(CICR) mechanism exists. (4) After $[Ca^{2+}]_i$ was decreased with the superfusion of $Ca^{2+}$-free solution containing thapsigargin, the recovery of $[Ca^{2+}]_i$ with reperfusion of 2.5mM $Ca^{2+}$ solution transiently exceeded the control level, suggesting that the depletion of $Ca^{2+}$ in ER induces $Ca^{2+}$ influx from extracellular medium via store-operated $Ca^{2+}$ influx(SOCI) mechanism. (5) $[Ca^{2+}]_i$ was not affected by the superfusion of 25mM $K^+$ Tyrode solution. These results suggest that intracellular $Ca^{2+}$ activity in osteoblast is regulated by transmembrane $Ca^{2+}$ flux via $Na^+-Ca^{2+}$ exchange, $Ca^{2+}$ release from the internal store (ER) via $Ca^{2+}$-induced $Ca^{2+}$ release, and store-operated $Ca^{2+}$ influx across the cell membrane.

• Journal of Naturopathy
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• v.11 no.2
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• pp.143-151
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• 2022

Background: The singing bowl is a bowl-shaped percussion instrument and is used in meditation and healing programs, but the mechanism of its clinical effects is unclear. Purpose: In this paper, we reviewed the peculiar acoustic property of the singing bowl sound and discussed on physical mechanisms of the clinical effects of the singing bowl sound. Methods: We studied the literature by reviewing it. Results: There are multiple pitches at adjacent frequencies in the singing bowl sound, and they give rise to the beat phenomenon. This results in a solid persisting beating felt in the singing bowl sound. Furthermore, the beat that depends on singing bowls and playing methods includes a rhythm often similar to the frequency band of brain waves (theta wave) observed in meditative states and induces a synchronization phenomenon in which the rhythm activates the brain waves in meditative states. Furthermore, we are to infer that the clinical effect of the singing bowl sound is closely associated with the synchronization of brain waves to the beat rhythm of the singing bowl sound. Conclusion: To clearly understand the clinical mechanism of the singing bowl sound, we suggest further systematic studies on the psychological and physiological responses to the beats of the singing bowl sound.

• Korean Journal of Agricultural and Forest Meteorology
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• v.15 no.3
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• pp.145-152
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• 2013

This study aimed to investigate the growth and physiological characters of Liriodendron tulipifera seedlings in responses to two different levels of elevated air temperature and $CO_2$ concentration. The seedlings were grown in environment-controlled growth chambers with two combinations of air temperature and $CO_2$ conditions: (1) $22^{\circ}C$ + ambient $CO_2$ $380{\mu}mol\;mol^{-1}$ and (2) $27^{\circ}C$ + $770{\mu}mol\;mol^{-1}$. Physiological characters such as growth, photosynthesis, and water use efficiency, were monitored for 85 days. The seedlings under the elevated treatment showed a greater amount of growth in tree height, compared with those under the control. Regarding the characteristics of assimilatory organs, the elevated treatment resulted in a greater amount of total leaf area, leaf unfolding, and dry weight per leaf area. No significant differences were found in photosynthesis capacity between the two treatments. The increase in water use efficiency with increased intercellular $CO_2$ partial pressure appeared overall lower in the seedling under the elevated treatment, compared with those under the control. The total leaf area of the seedlings under the elevated treatment was larger than that under the control, indicating a higher amount of photosynthesis. In addition, an increase of root growth was noted under the elevated treatment. A resistance mechanism of water stress may be attributed to a higher amount of organ growth as well as the tree height under the elevated treatment than the control.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.41 no.spc1
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• pp.25-45
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• 1996

Soyfoods have potential roles in the prevention and treatment of chronic diseases, most notably cancer, osteoporosis, and heart disease. There is evidence that carcinogenesis are supressed by isolated soybean derived products in vivo such as a protease inhibitor, phytic acid, saponins and isoflavones. It is believed that supplementation of human diets with soybean products markedly reduces human cancer mortality rates. Especially, recent papers recognize the potential benefit of soybean isoflavone components for reducing the risk of various cancers. Isoflavones exhibit a multitude of medicinal effects that influence cell growth and regulation, which may have potential value in the prevention and treatment of cancer. In addition to potential biological effects, soybean isoflavones have the important physiological functions such as the induction of Bradyrizobium japonicum nod genes and the responses of soybean tissues to infection by Phytophthora megasperma as well as biochemical activities such as antifungal and antibacterial actions. Genistin, daidzin, glycitin and their aglycone (genistein, daidzein, glycitein) are the principal isoflavones found in soybean. Malonyl and acetyl forms have also been detected but they are thermally unstable and are usually transformed during the processing in glucoside form. Most soy products, with the exception of soy sauce, alcohol-extracted soy protein concentrate, and soy protein isolate, have total isoflavone concentrations similar to those in the whole soybean. Soybean-containing diets inhibit mammary tumorigenesis in animal models of breast cancer, therefore, it is possible that dietary isoflavones are an important factor accounting for the lower incidence and mortality from breast cancer. Of the total soybean seed isoflavones, $80\~90\%$ were located in cotyledons, with the remainder in the hypocotyls. The hypocotyls had a higher concentrations of isoflavones on a weight basis compared with cotyledons. Isoflavone contents were influenced by genetics, crop years, and growth locations. The effect of crop year had a greater impact on the isoflavone contents than that of location. The climate condition might be the attribution factor to variation in isoflavone contents. Also, while the isoflavone content of cotyledons exhibited large variations in response to high temperature during seed development, hypocotyls showed high concentration in isoflavone content. So, it is concluded that one of the factors affecting isoflavone content in soybean seeds is temperature during seed development. High temperature, especially in maturity stage, causes lower isoflavone content in soybean seed. It is also suggested that there may exist a different mechanism to maintain isoflavone contents between cotyledon and seed hypocotyls. In a conclusion, soy foods may be able to have a significant beneficial impact on public health.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.239-239
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• 2017

The enhancement of leaf photosynthetic capacity can have the potential to improve the seed yield of soybean. Key targets for the increase of leaf photosynthetic capacity remains unclear in soybean. Peking, Chinese local variety, has been the useful material for soybean breeding since it shows various resistances against biotic and abiotic stress. Sakoda et al., 2017 reported that Peking had the higher capacity of leaf photosynthesis than Enrei, Japanese elite cultivar. They identified the genetic factors related to high photosynthetic capacity of Peking. The objective of this study is to elucidate the physiological basis underlying high photosynthetic capacity of Peking. Peking and Enrei were cultivated at the experimental field of the Graduate School of Agriculture, Kyoto University, Kyoto, Japan. The sowing date was July 4, 2016. Gas exchange parameters were evaluated at the uppermost fully expanded leaves on 43, 49, and 59 days after planting (DAP) with a portable gas exchange system, LI-6400. The leaf hydraulic conductance, $K_{leaf}$, was determined based on the water potential and transpiration rate of the uppermost fully expanded leaves on 60 DAP. The morphological traits related to leaf photosynthesis were analyzed at the same leaves with the gas exchange measurements. The light-saturated $CO_2$ assimilation rate ($A_{sat}$) of Peking was significantly higher than that of Enrei at 43 and 59 DAP while the stomatal conductance ($g_s$) of Peking was significantly higher at all the measurements (p < 0.05). It suggested that high $A_{sat}$ was mainly attributed to high $g_s$ in Peking. $g_s$ is reported to be affected by the morphological traits and water status inside the leaf, represented by $K_{leaf}$, in crop plants. The tendency of the variation of the stomatal density between two cultivars was not consistent throughout the measurements. On the other hand, $K_{leaf}$ of Peking was 59.0% higher than that of Enrei on 60 DAP. These results imply that high $g_s$ might be attributed to high $K_{leaf}$ in Peking. Further research is needed to reveal the mechanism to archive high $g_s$ on the basis of water physiology in Peking. The knowledge combining the genetic and physiological basis underlying high photosynthetic capacity of Peking can be useful to improve the biomass productivity of soybean.

• Journal of Korean Society of Forest Science
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• v.89 no.3
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• pp.452-460
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• 2000

This study was to investigate the growth characteristics, physiological adaptation of Pinus densiflora(Japanese Red Pine) seedlings at the artificial canopy gap in the Quercus acutissima plantation and to analyze its natural regeneration mechanism. Photosynthetic and transpiration rates were analyzed by different levels of photosynthetically active radiation and by seedling growth. Comparing to seedlings at the open area, those at the canopy gap showed more growth in height than in diameter with different levels of light quality and low light intensity, and the increase rate of dry weight was higher in the aboveground than in the underground, maintaining relatively high T/R rate. The C/F(the ratio of non-photosynthetic organs to photosynthetic organs in dry weight) of the aboveground at the canopy gap was higher than that at the open area by 0.1~0.2, while light saturation and light compensation points at the canopy gap were lower than that at the open area by $300{\mu}mol\;m^{-2}s^{-1}$ and 40%, respectively. The seedlings appeared to have shade tolerance to a certain extent at the young growth stage despite Pinus densiflora is typically classified shade-intolerant species. With light intensity lower than $400{\sim}450{\mu}mol\;m^{-2}s^{-1}$, photosynthetic rate and water use efficiency relatively increased by effective use of light energy.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.1
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• pp.62-66
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• 2002

Hypertension is not only a well-established cardiovascular risk factor but also increase the risk of atherosclerosis. Most studies conducted to investigate the effectiveness of treatment for cardiovascular disease such as hypertension have focused primarily on conventional drug and physiotherapeutic treatments. BanhabackchulChunma-tang(半夏白朮天麻湯:BCT) is popular herbal medicine used in clinic for the treatment of various symptoms of drulatory disorders and weakness of digestive system, including anorexa and nausea with vertigo, severe headache, vomiting and so on. However, the mechanisms underlying its efficacy are unknown. This study investigated the effects of BCT as an alternative medication on the contraction induced by phenylephrine and KCI in rat thoratic aorta. BCT revealed siginificant relaxation on phenylephrine-induced arterial contraction, but revealed noncompetitive effect on concentration responses of phenylephrine-induced contraction. Treatment of N-L/sup ω/ -argine methyl ester(L-NAME) and methylene blue(MB)(10/sup -5/M) reduced the relaxation of BCT. BCT also increased in vitro NO production. It suggest that the relaxation effect of BBT is related with NO pathway, becausse the effect of L-NAME and MB are due to inhibition of NO synthesis from endothelial cells. These results indicate that BCT would be effective in hypertension treatment and its mechanism of relaxtion on arterial contraction is likely to be related with NO production, blocking of α-receptor and signal transduction after receptor activation.