• 동의생리병리학회지
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• 제27권5호
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• pp.683-687
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• 2013

Evacuation disorder(ED) is frequently observed in the elderly people. In this study, we investigated the tongue color properties in the elderly. 327 subjects were participated in this study and classified into normal group (n=95) and ED group (n=23) by two Korean Oriental Medicine doctors. The tongue images were acquired by using computerized tongue diagnosis system, and its color were linearly corrected base on CIE $L^*a^*b^*$ values of 12 color samples. The tongue region was segmented from acquired image and divided into two regions along the vertical direction. In order to estimate color properties of the tongue, a color histogram was calculated for the root region based on the CIE $L^*$ and $a^*$ values, and differences of color histogram values between normal and ED groups were computed based on the Mann-Whitney U test. As results, pixels corresponding to typical colors of the pale tongue and thin tongue coating were significantly more distributed in ED than those in normal group(p<0.05). The tongue color of the root region in ED was revealed to be different from those in healthy subjects.

• 동의신경정신과학회지
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• 제15권1호
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• pp.9-25
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• 2004

Behavioral characteristics of Attention Deficit Hyperactivity Disorder(ADHD) is one of the most common mental disorders among children.child psyachiatry. Inattention, Hyperactivity that is done by hyperkinesis or minimal brain dysfunction is major sypmton in ADHD, But etiology and pathological facor of ADHD is very much or unkown.. We brought to about a Study on the Oriental - medical pathologic Understanding about Inattention, Hyperactivity symptom in ADHD within Don yui bo gam Book are as follows. 1. Oriental medical pathologic concepts about Inattention, Hyperactivity are continuous with process of Yang Qi(陽氣), an unbalance of qi(氣) and shen ming(神明), excess of seven emotions(七情), pathology of Huo(火). 2. Immanent factors in inattention, Hyperactivity are improper diet, overtiredness and seven emotions, are continuous with pathological process of the heart, liver, gall bladder, spleen, stomach, kidneys. 3. In oriental medicine, considered as a child's qi of shao yang, dynamic physiological feature, excess and want of yin and yang, organs and bowels, immanently imbalance in growth rather than a child's mental disorder 4. Inattention, looseness in ADHD-PI type are continuous with forgetfulness, improper overtiredness, shortage of qi, the interior heat syndrome due to yin deficiency within Don yui bo gam Book 5. Hyperactivity, impulsive actions in ADHD-C type are continuous with sudden palpitation, severe palpitation, delirium, fidgeting due to deficiency, fidgetiness, hyperactivity of huo due to yin deficiency, fever, febrile disease with accumulation of blood.

• 동의생리병리학회지
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• 제21권6호
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• pp.1663-1669
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• 2007

Acute transverse myelitis(ATM) is defined as an acute intramedullary dysfunction of the spinal cord, ascendng or static involving both halves of the cord and appearing without any history of previous neurological diseases due to traumatic accident, tumor of all kind, encephalitis and of course excluding all possible viral, bacterial and fungal infection. It is mainly characterized by acute motor disorder of both limbs in respect to which spinal segments are affected as well as sensory disorder and dysuria & dyschezia. The exact cause is unknown, however it is recently suggested that immunological factors are highly involved. It has been reported by several reliable sources that it is often accompanied by immunological diseases such as systemic lupus erythematosus(SLE). As treatments non steroid anti-inflammatory drugs(NSAIDS) are primarily recommended as to steroids, limited doses are injected only with the proper prescription from the physician. Operative methods are not options as traumatic accidents and tumors are excluded as factors. To enhance muscle strength and prevent articular contracture physical therapy and passive exercise is imperative. The following patient whose chief complaints were mainly about hypoesthesia of Rt. lower limb and stiffness of phalanges of both fingers as well as to weakness of lower extermity. Therefore it has been diagnosed as arthalgia syndrome. In oriental medicine factors such as wind evil heat-evil, dampness-heat evil, cold evil cause the arthalgia syndrome. In this case the patient was diagnosed as dampness-heat evil and herbal medicine Chunglijagam-Tang and Dong-Qi acupuncture was applied to treat bladder disorder.

• 동의생리병리학회지
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• 제20권6호
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• pp.1769-1773
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• 2006

This study is attempted to analyze characteristics of personality by Minnesota Multiphasic Personality Inventory responses in Neck Pain patients. 21 Neck Pain patients and 28 control group were tested by MMPI and QSCC II. It is analyzed by one-way ANOVA, chi-square test, t-test, Duncan method is used as ex-post test. 21 Neck Pain patients were classified into three constitutions by QSCC II. There were 8 of Soyangin(38.1%), 2 of Soeumin(9.5%) and 11 of Taeumin(52.4%)> In the analysis of personality disorder scale of MMPI, the difference was not valid by constitution. In the analysis of personality disorder scale of MMPI, Neck Pain patients group showed higher scores than control group in ANT, CPS, PAG, PAR, DEP, STY, AVD, SZD scale.

• 대한불안의학회지
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• 제4권1호
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• pp.3-10
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• 2008

The purpose of this review was to investigate the neurophysiological and neuroimaging characteristics of patients with depression and anxiety reported in previous studies. A literature search was conducted using Medline and psychiatric textbooks. "Electroencephalography (EEG)", "Event Related Potentials (ERP)", "functional neuroimaging", "heart rate variability (HRV)" and "depression or anxiety" were used as key words. A physiological finding indicated that there was a higher degree of relativity with regards to prefrontal dysfunction in patients with depression. Right prefrontal lobe hyperactivity and left prefrontal hypoactivity were consistently observed, and abnormalities were observed in other regions (ACC, hippocampus, amygdala, etc.). Therefore, dysfunctions in these areas are related to depressive symptoms. In patients with anxiety disorder, each emotional condition showed specific activation patterns in different brain regions, such as the prefrontal cortex, occipital lobe, temporal lobe, hippocampus, and limbic system, including the amygdala. However, in the majority of patients with anxiety disorder, the degree of activation was higher in the right hemisphere than in the left hemisphere. The current data supports that there is a difference in brain dysfunction characteristics between depression and anxiety and that the different activations of various brain regions would play a significant role in the pathophysiology of depression and anxiety disorder.

• 한국산학기술학회논문지
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• 제17권9호
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• pp.387-393
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• 2016

본 논문은 불안장애 환자 6명을 대상으로 32채널 정량화 뇌파(Quantitative Electroencephalograpy)와 뉴로피드백을 이용하여 뇌파를 분석하고 훈련하여 불안장애 환자의 정량화 뇌파 기반 뉴로피드백 훈련의 효과성에 대해 임상연구를 진행하였다. 불안수준을 측정하기 위해 심리생리학적 검사인 정량화 뇌파와 BAI(Beck Anxiety Inventory)를 실시하고, 그 결과를 통해 뉴로피드백 훈련도 진행하였다. 훈련 전 불안장애 환자의 정량화 뇌파 검사를 분석한 결과 6명 환자 모두의 측두엽에서 고베타파가 과잉활성화 된 양상을 볼 수 있었으며, 우뇌 측두엽(T4)의 세기(M=31.07)가 좌뇌 측두엽(T3)의 세기(M=29.11)보다 높았다. 이 결과를 바탕으로 뉴로피드백 프로토콜을 설정하고 훈련을 진행한 결과, 우뇌 측두엽의 베타파가 6명 환자 모두에게서 유의미하게 감소하였다. BAI점수를 분석한 결과 훈련 전의 평균이 23.57, 훈련 후의 평균이 12.14로 뉴로피드백 훈련 후 불안이 감소함을 알 수 있었다. 또한 약물복용을 했던 2명의 환자 중 한 명은 복용량이 줄어들었고 다른 한명은 약물을 중단하게 되었다. 이 결과는 정량화 뇌파 기반 뉴로피드백 훈련이 불안장애를 효과적으로 개선시키는데 사용될 수 있다는 것을 보여준다 하겠다.

• 생물환경조절학회지
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• 제27권3호
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• pp.191-198
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• 2018

본 연구의 목적은 온도와 토양수분에 따른 마늘의 생육, 생리장해 및 수량에 미치는 영향을 구명하고자 실시하였다. 실험은 온도가 $6^{\circ}C$ 차이가 나는 온실에서 수행되었는데, 정식부터 수확까지 외기(A)보다 $3^{\circ}C(A+3^{\circ}C)$, $6^{\circ}C(A+6^{\circ}C)$ 고온조건, 토양수분은 적습(OI) 대비 수확기 무렵의 다습(EI) 처리를 하였다. 그 결과, 마늘 생육특성은 온도와 토양수분 조건($0.34m^3/m^3$)에 따라 고도의 유의성을 보여 고온일수록 그리고 적습 처리구일수록 컸다. 초장은 외기보다 $A+6^{\circ}C-OI$ 처리구에서 47.4cm로 가장 컸으며, 엽장과 엽폭 역시 외기보다 $A+6^{\circ}C-OI$ 처리구가 각각 16.1cm, 2.4cm로 가장 컸다. 마늘재배 기간 중 외기보다 $3^{\circ}C$, $6^{\circ}C$ 고온조건이 되면 스펀지마늘 발생율이 높아져 $A+6^{\circ}C-OI$ 처리구는 12.9% 발생하였고, A-EI 처리구에서는 전혀 발생하지 않았으며, 인편무게와 1쪽당 무게는 $A+6^{\circ}C$ 고온구에서 크게 감소하여 수량이 외기대비 $A+6^{\circ}C$ 처리구는 평균 51%, $A+3^{\circ}C$ 처리구는 평균 22% 감소하였다. 따라서, 마늘재배시 외기보다 $6^{\circ}C$ 고온조건과 다습조건이 되면 상품수량 감소하고, 생리장해 발생이 많아지는 것으로 나타났다.

• 정신신체의학
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• 제14권1호
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• pp.25-32
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• 2006

연구목적 : 두통은 일생 동안 90% 이상의 사람들이 경험하게 되는 임상 증후군이다. 이 논문은 긴장성두통과 편두통의 현재의 개념과 바이오피드백 치료 및 이완요법에 대해 요약하였다. 방법: Pubmed/Medline 검색에 포함된 용어는 바이오피드백(biofeedback), 이완(relaxation), 생리적(physiological), 행동적 (behavioral), 비약물의 (nonpharmacological), 두통(headache), 긴장성두통(tension-type headache), 그리고 편두통(migraine)이었다. 검색되지 않은 저술 중 적절한 논문과 바이오피드백을 수행하는 전문가의 의견도 포함시켰다. 결과 : 두통은 바이오피드백 및 이완요법을 포함한 행동치료적 개입에 의해 치료될 수 있는 정신생리장애(psycho-physiological disorder)로 볼 수 있다. 두통에서 이러한 치료들을 통해 임상적 호전을 보인다는 보고들이 지속되고 있다. 또한, 환자에게 실제 적용 시 고려할 점도 제시하였다. 결론: 바이오피드백 치료와 이완요법은 단독 또는 약물치료와 함께 두통 환자에게 제공될 수 있는 효과적인 치료법으로 제안된다.

• Nutrition Research and Practice
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• 제15권2호
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• pp.137-159
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• 2021

Long-chain (LC) n-3 polyunsaturated fatty acids (n-3 PUFAs), in particular docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), are nutrients involved in many metabolic and physiological processes, and are referred to as n-3 LCPUFA. They have been extensively studied for their effects in human nutrition and health. This paper provides an overview on metabolism, sources, dietary intake, and status of n-3 LCPUFA. A summary of the dietary recommendations for n-3 LCPUFAs for different age groups as well as specific physiological conditions is provided. Evidence for n-3 LCPUFA in cardiovascular diseases, including new studies, is reviewed. Expert recommendations generally support a beneficial effect of n-3 LCPUFA on cardiovascular health and recommend a daily intake of 500 mg as DHA and EPA, or 1-2 servings of fish per week. The role of n-3 LCPUFA on brain health, in particular neurodegenerative disorders and depression, is reviewed. The evidence for beneficial effects of n-3 LCPUFA on neurodegenerative disorders is non-conclusive despite mechanistic support and observational data. Hence, no definite n-3 LCPUFA expert recommendations are made. Data for the beneficial effect of n-3 LCPUFA on depression are generally compelling. Expert recommendations have been established: 200-300 mg/day for depression; up to 1-2 g/day for major depressive disorder. Recent studies support a beneficial role of n-3 LCPUFAs in reducing the risk for premature birth, with a daily intake of 600-800 mg of DHA during pregnancy. Finally, international experts recently reviewed the scientific evidence on DHA and arachidonic acid (ARA) in infant nutrition and concluded that the totality of data support that infant and follow-on formulas should provide both DHA and ARA at levels similar to those in breast milk. In conclusion, the available scientific data support that dietary recommendations for n-3 LCPUFA should be established for the general population and for subjects with specific physiological conditions.

• 동의생리병리학회지
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• 제16권5호
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• pp.1066-1069
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• 2002

Wilson's disease is a rare inborn error of metabolism inherited as a autosomal recessive trait. The disease has varied mode of manifestations. It is characterized by different neurologic disorder and hepatic disease. I experienced a case of Wilson's disease in 40 year old woman who was suffered from liver cirrhosis, severe anorexia, and classical neurologic symptoms such as tremour, dysarthria and ataxia. The symptoms was not relieved by D-penicillamine, Youngyanggaksan and Samchulgunbi-tang but anorexia was improved significantly by same medication.