• 제목/요약/키워드: Physics-based model

검색결과 607건 처리시간 0.029초

Bifurcation analysis of budding yeast cell cycle

  • Nguyen, Cuong;Yoon, Chang-No;Kim, Hak-Yong;Han, Seung-Kee
    • 한국생물정보학회:학술대회논문집
    • /
    • 한국생물정보시스템생물학회 2004년도 The 3rd Annual Conference for The Korean Society for Bioinformatics Association of Asian Societies for Bioinformatics 2004 Symposium
    • /
    • pp.50-56
    • /
    • 2004
  • Bifurcation analysis of cell cycle regulation in the budding yeast is performed basedon the mathematical model by Chen et al [Molecular biology of cell, 11:369-391, 2000]. On the bifurcation diagram, locations of both stable and unstable solutions of the nonlinear differential equations are presented by taking the mass of cell as a controlparameter. Based on the bifurcation diagram, dynamic mechanism underlying the 'start' transition, initiation of a new round of cell cycle, and the 'finish' transition, completion of cell cycle and returning back to the initial state, is discussed: the 'start' transition is a transition from a stable fixed solution for a small mass and to an oscillatory state for a large mass, and the 'finish' transition is a switching back to the stable fixed solution from the oscillatory state. To understand the role of the genes during the cell cycle regulation, bifurcation diagrams for the mutants are compared with that of the wild type.

  • PDF

Impedance spectroscopy for lifetime analysis of OLED

  • Yoon, Chul-Oh;Kim, Hyun-Chul;Yi, Seok-Kyung;Kong, Ung-Gul;Lee, Nam-Heon;Lee, Chang-Hee
    • 한국정보디스플레이학회:학술대회논문집
    • /
    • 한국정보디스플레이학회 2002년도 International Meeting on Information Display
    • /
    • pp.137-140
    • /
    • 2002
  • The frequency response analysis of complex impedance spectra using small perturbation ac impedance spectroscopy is an informative method of OLED performance characterization and lifetime analysis. Using simple RC equivalent circuit mode,l macroscopic nonliniear transport properties of semiconductive emission/transport layers can be analyzed and parameterized. We present the bias voltage dependence and aging effect in impedance spectra measured from an ITO/CuPC/TPD/$Alq_3$/LiF/Al OLED device, and discuss possible failure mechanism based on impedance model parameters.

  • PDF

EEG model by statistical mechanics of neocortical interaction

  • Park, J.M.;Whang, M.C.;Bae, B.H.;Kim, S.Y.;Kim, C.J.
    • 대한인간공학회지
    • /
    • 제16권2호
    • /
    • pp.15-27
    • /
    • 1997
  • Brain potential is described using the mesocolumnar activity defined by averaged firings of excitatory and inhibitory neuron of neocortex. Lagrangian is constructed based on SMNI(Statistical Mechanics of Neocortical Interaction) and then Euler Lagrange equation is obtained. Excitatory neuron firing is assumed to be amplitude- modulated dominantly by the sum of two modes of frequency .omega. and 2 .omega. . Time series of this neuron firing is calculated numerically by Euler Lagrangian equation. I .omega. L related to low frequency distribution of power spectrum, I .omega. H hight frequency, and Sd(standard deviation) were introduced for the effective extraction of the dynamic property in the simulated brain potential. The relative behavior of I .omega. L, I .omega. H, and Sd was found by parameters .epsilon. and .gamma. related to nonlinearity and harmonics respectively. Experimental I .omega L, I .omega. H, and Sd were obtained from EEG of human in rest state and of canine in deep sleep state and were compared with theoretical ones.

  • PDF

Search for galaxy clusters in SA22

  • 김재우;임명신;현민희
    • 천문학회보
    • /
    • 제37권2호
    • /
    • pp.83.1-83.1
    • /
    • 2012
  • The galaxy cluster is a good laboratory to test the cosmological model as well as the evolution of galaxies in the dense region. However the lack of wide and deep near-IR datasets has prevented to identify galaxy clusters at z>1. Here we merge a wide, deep near-IR datasets of UKIDSS DXS (J and K bands) and IMS (J band) with the CFHT Legacy Survey (CFHTLS) ugriz catalogue to detect galaxy clusters. We identify candidate galaxy clusters at z>0.8, where the near-IR dataset plays an important role to detect galaxies efficiently. The cluster mass is also estimated based on the cluster richness and the semi-analytical cosmological simulation.

  • PDF

Effects of Gas-surface Interaction Models on Spacecraft Aerodynamics

  • Khlopkov, Yuri Ivanovich;Chernyshev, Sergey Leonidovich;Myint, Zay Yar Myo;Khlopkov, Anton Yurievich
    • International Journal of Aeronautical and Space Sciences
    • /
    • 제17권1호
    • /
    • pp.1-7
    • /
    • 2016
  • The influence of boundary condition of the bodies with gas flows is one of the most important problems in high-altitude aerodynamics. In this paper presents the results of the calculation of aerodynamic characteristics of aerospace vehicle using Monte-Carlo method based on three different gas-surface interaction models - Maxwell model, Cercignani-Lampis-Lord (CLL) model and Lennard-Jones (LJ) potential. These models are very sensitive for force and moment coefficients of aerospace vehicle in the hypersonic free molecular flow. The models, method and results can be used for new generation aerospace vehicle design.

DEBRIS DISKS AND THE ZODIACAL LIGHT EXPLORED BY THE AKARI MID-INFRARED ALL-SKY SURVEY

  • Ishihara, Daisuke;Takeuchi, Nami;Kondo, Toru;Kobayashi, Hiroshi;Kaneda, Hidehiro;Inutsuka, Shu-ichiro;Oyabu, Shinki;Nagayama, Takahiro;Fujiwara, Hideaki;Onaka, Takashi
    • 천문학논총
    • /
    • 제32권1호
    • /
    • pp.67-71
    • /
    • 2017
  • Debris disks are circumstellar dust disks around main-sequence stars. They are important observational clues to understanding the planetary system formation. The zodiacal light is the thermal emission from the dust disk in our Solar system. For a comprehensive understanding of the nature and the evolution of dust disks around main-sequence stars, we try a comparative study of debris disks and the zodiacal light. We search for debris disks using the AKARI mid-infrared all-sky point source catalog. By applying accurate flux estimate of the photospheric emission based on the follow-up near-infrared observations with IRSF, we have improved the detection rate of debris disks. For a detailed study of the structure and grain properties in the zodiacal dust cloud, as an example of dust disks around main-sequence stars, we analyze the AKARI mid-infrared all-sky diffuse maps. As a result of the debris disks search, we found old (>1 Gyr) debris disks which have large excess emission compared to their age, which cannot be explained simply by the conventional steady-state evolution model. From the zodiacal light analysis, we find the possibility that the dust grains trapped in the Earth's resonance orbits have increased by a factor of ~3 in the past ~20 years. Combining these results, we discuss the non-steady processes in debris disks and the zodiacal light.

Adaptively selected autocorrelation structure-based Kriging metamodel for slope reliability analysis

  • Li, Jing-Ze;Zhang, Shao-He;Liu, Lei-Lei;Wu, Jing-Jing;Cheng, Yung-Ming
    • Geomechanics and Engineering
    • /
    • 제30권2호
    • /
    • pp.187-199
    • /
    • 2022
  • Kriging metamodel, as a flexible machine learning method for approximating deterministic analysis models of an engineering system, has been widely used for efficiently estimating slope reliability in recent years. However, the autocorrelation function (ACF), a key input to Kriging that affects the accuracy of reliability estimation, is usually selected based on empiricism. This paper proposes an adaption of the Kriging method, named as Genetic Algorithm optimized Whittle-Matérn Kriging (GAWMK), for addressing this issue. The non-classical two-parameter Whittle-Matérn (WM) function, which can represent different ACFs in the Matérn family by controlling a smoothness parameter, is adopted in GAWMK to avoid subjectively selecting ACFs. The genetic algorithm is used to optimize the WM model to adaptively select the optimal autocorrelation structure of the GAWMK model. Monte Carlo simulation is then performed based on GAWMK for a subsequent slope reliability analysis. Applications to one explicit analytical example and two slope examples are presented to illustrate and validate the proposed method. It is found that reliability results estimated by the Kriging models using randomly chosen ACFs might be biased. The proposed method performs reasonably well in slope reliability estimation.

해역별 최적 해빈 안정화 공법 선정 Platform 개발을 위한 기초연구 II - 양빈 된 해빈 침식률 산정을 위한 물리기반 해빈 지형모형 개발을 중심으로 (Preliminary Study on the Development of a Platform for the Optimization of Beach Stabilization Measures against Beach Erosion II - Centering on the Development of Physics-Based Morphology Model for the Estimation of an Erosion Rate of Nourished Beach)

  • 조용준
    • 한국해안·해양공학회논문집
    • /
    • 제31권5호
    • /
    • pp.320-333
    • /
    • 2019
  • 양빈이 수행된 해빈의 침식률 산정을 위한 물리기반 해빈 지형모형이 제시되었다. 동수역학 모형은 OpenFOAM에 기반 한 tool box인 IHFOAM으로 구성되며, Morphology 모형은 부유사를 대상으로 한 이송확산방정식, 소류사 이송을 포함한 표사 수지 개념으로부터 유도된 Exner 식으로 구성하였다. 표사 이송여부, 부유사 농도저면 경계치, 소류사 이송률 산출과정에는 Shields Diagram, 삼차원 수치 모의된 유동계 정보로부터 직접 산출된 저면 전단응력이 활용된다. 본 논문에서 제시된 지형 모형을 검증하기 위해, 경사가 1/6인 단조 해안에서의 천수과정, 쇄파과정, 이에 따른 저면 변화를 수치 모의하였다. 모의결과 비선형 천수과정에서 예상되는 왜곡되고 왜도된 저면전단응력이 비교적 정확히 모의되었다. 또한 전빈에서 진행되는 쇄파로 인해 부유되고 침식된 표사가 up-rush에 의해 후빈으로 이동되어 형성되는 swash bar와 up-rush 정점에서 방향을 바꾸어 먼 바다 방향으로 진행되는 back-wash에 의해 쓸려간 표사가 수심증가에 따라 back-wash 흐름 강도가 약해지면서 퇴적하여 형성되는 breaker bar가 성공적으로 모의되는 것을 확인할 수 있었다.

GEANT4 Medical Linac2 예제를 이용한 6 MV 선형가속기 광자선속의 기초특성과 연구방법 (Study on the 6 MV Photon Beam Characteristics and Analysis Method from Medical Linear Accelerators Using Geant4 Medical Linac2 Example)

  • 김병용;김형동;김성진;오세안;강정구;김성규
    • 한국의학물리학회지:의학물리
    • /
    • 제22권2호
    • /
    • pp.79-84
    • /
    • 2011
  • 본 연구에서는 GEANT4 toolkit을 이용하여 의료용 선형가속기에 대한 몬테칼로(Monte Carlo) 전산모사를 하였다. Medical Linac2 예제를 수정해서 사용하였다. 에너지스펙트럼, 최빈에너지, 평균에너지를 EGS4 결과와 비교 하였고 선속의 중심에서부터 반경에 따른 단위면적당 광자수, 단위면적당 에너지, 평균에너지를 분석하였다. 그 결과 EGS4 결과와 큰 차이를 보이지 않기 때문에 Medical Linac2 예제의 선속특성에 관한 전산모사에 큰 문제점은 없는 것으로 판단된다. 같은 헤드구조에서도 Physics List의 모델에 따라서는 결과에 차이가 발생하므로 연구 환경에 알맞은 Physics List 모델을 선택하는 것이 중요하다고 판단된다. 본 연구는 처음 몬테칼로 전산모사를 접하는 사용자가 선속특성에 대한 전산모사를 수행하고 6 MV 광자선속의 특성을 분석하는 과정에 많은 도움이 될 것으로 사료된다.

Enhanced mass balance Tafel slope model for computer based FEM computation of corrosion rate of steel reinforced concrete coupled with CO2 transport

  • Hussain, Raja Rizwan
    • Computers and Concrete
    • /
    • 제8권2호
    • /
    • pp.177-192
    • /
    • 2011
  • This research paper aims at computer based modeling of carbonation induced corrosion under extreme conditions and its experimental verification by incorporating enhanced electrochemical and mass balance equations based on thermo-hygro physics with strong coupling of mass transport and equilibrium in micro-pore structure of carbonated concrete for which the previous research data is limited. In this paper the carbonation induced electrochemical corrosion model is developed and coupled with carbon dioxide transport computational model by the use of a concrete durability computer based model DuCOM developed by our research group at concrete laboratory in the University of Tokyo and its reliability is checked in the light of experiment results of carbonation induced corrosion mass loss obtained in this research. The comparison of model analysis and experiment results shows a fair agreement. The carbonation induced corrosion model computation reasonably predicts the quantitative behavior of corrosion rate for normal air dry relative humidity conditions. The computational model developed also shows fair qualitative corrosion rate simulation and analysis for various pH levels and coupled environmental actions of chloride and carbonation. Detailed verification of the model for the quantitative carbonation induced corrosion rate computation under varying relative conditions, different pH levels and combined effects of carbonation and chloride attack remain as scope for future research.