• Title/Summary/Keyword: Physical distribution

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Development of a Method for Improving the Electric Field Distribution in Patients Undergoing Tumor-Treating Fields Therapy

  • Sung, Jiwon;Seo, Jaehyeon;Jo, Yunhui;Yoon, Myonggeun;Hwang, Sang-Gu;Kim, Eun Ho
    • Journal of the Korean Physical Society
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    • v.73 no.10
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    • pp.1577-1583
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    • 2018
  • Tumor-treating fields therapy involves placing pads onto the patient's skin to create a low- intensity (1 - 3 V/cm), intermediate frequency (100 - 300 kHz), alternating electric field to treat cancerous tumors. This new treatment modality has been approved by the Food and Drug Administration in the USA to treat patients with both newly diagnosed and recurrent glioblastoma. To deliver the prescribed electric field intensity to the tumor while minimizing exposure of organs at risk, we developed an optimization method for the electric field distribution in the body and compared the electric field distribution in the body before and after application of this optimization algorithm. To determine the electric field distribution in the body before optimization, we applied the same electric potential to all pairs of electric pads located on opposite sides of models. We subsequently adjusted the intensity of the electric field to each pair of pads to optimize the electric field distribution in the body, resulting in the prescribed electric field intensity to the tumor while minimizing electric fields at organs at risk. A comparison of the electric field distribution within the body before and after optimization showed that application of the optimization algorithm delivered a therapeutically effective electric field to the tumor while minimizing the average and the maximum field strength applied to organs at risk. Use of this optimization algorithm when planning tumor-treating fields therapy should maintain or increase the intensity of the electric field applied to the tumor while minimizing the intensity of the electric field applied to organs at risk. This would enhance the effectiveness of tumor-treating fields therapy while reducing dangerous side effects.

Impact of Level of Physical Activity on Healthcare Utilization among Korean Adults (성인의 신체활동 정도가 의료이용에 미치는 영향)

  • Kim, Ji-Yun;Park, Seung-Mi
    • Journal of Korean Academy of Nursing
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    • v.42 no.2
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    • pp.199-206
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    • 2012
  • Purpose: This study was done to identify the impact of physical activity on healthcare utilization among Korean adults. Methods: Drawing from the 2008 Korean National Health and Nutrition Examination Survey (NHANES IV-2), data from 6,521 adults who completed the Health Interview and Health Behavior Surveys were analyzed. Association between physical activity and healthcare utilization was tested using the $X^2$-test. Multiple logistic regression analysis was used to calculate the odds ratios of using outpatient and inpatient healthcare for different levels of physical activity after adjusting for predisposing, enabling, and need factors. A generalized linear model applying a negative binomial distribution was used to determine how the level of physical activity was related to use of outpatient and inpatient healthcare. Results: Physically active participants were 16% less likely to use outpatient healthcare (OR, 0.84; 95% CI, 0.74-0.97) and 23% less likely to use inpatient healthcare (OR, 0.77; 95% CI, 0.63-0.93) than physically inactive participants. Levels of outpatient and inpatient healthcare use decreased as levels of physical activity increased, after adjusting for relevant factors. Conclusion: An independent association between being physically active and lower healthcare utilization was ascertained among Korean adults indicating a need to develop nursing intervention programs that encourage regular physical activity.

Dose Distribution According to the Tissue Composition Using Wedge Filter by Radiochromic Film (쐐기필터 사용 시 레디오크로믹 필름을 이용한 조직에 따른 선량분포 연구)

  • Kim, Yon-Lae;Lee, Jeong-Woo;Park, Byung-Moon;Jung, Jae-Yong;Park, Ji-Yeon;Suh, Tae-Suk
    • Journal of radiological science and technology
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    • v.35 no.2
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    • pp.157-164
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    • 2012
  • The purpose of this study is to analyze the dose distribution when wedge filter is used in the various tissue electron density materials. The dose distribution was assessed that the enhanced dynamic wedge filter and physical wedge filter were used in the solid water phantom, cork phantom, and air cavity. The film dosimetry was suitable simple to measure 2D dose distribution. Therefore, the radiochromic films (Gafchromic EBT2, ISP, NJ, USA) were selected to measure and to analyze the dose distributions. A linear accelerator using 6 MV photon were irradiated to field size of $10{\times}10cm^2$ with 400 MUs. The dose distributions of EBT2 films were analyzed the in-field area and penumbra regions by using dose analysis program. In the dose distributions of wedge field, the dose from a physical wedge was higher than that from a dynamic wedge at the same electron density materials. A dose distributions of wedge type in the solid water phantom and the cork phantom were in agreements with 2%. However, the dose distribution in air cavity showed the large difference with those in the solid water phantom or cork phantom dose distributions. Dose distribution of wedge field in air cavity was not shown the wedge effect. The penumbra width, out of the field of thick and thin, was observed larger from 1 cm to 2 cm at the thick end. The penumbra of physical wedge filter was much larger average 6% than the dynamic wedge filter. If the physical wedge filter is used, the dose was increased to effect the scatter that interacted with photon and physical wedge. In the case of difference in electron like the soft tissue, lung, and air, the transmission, absorption, and scattering were changed in the medium at high energy photon. Therefore, the treatment at the difference electron density should be inhomogeneity correction in treatment planning system.

The Assessment on the Characteristics of Quantitative Image in Digora$\textregistered$ (Digora$\textregistered$에서 정량영상의 특성에 대한 평가)

  • Kim Jae-Duk
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.29 no.2
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    • pp.397-405
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    • 1999
  • Purpose: To clarify the usefulness and the limitation of Digora system/sup (R)/ by evaluating the physical characteristics as the quantitative image on Image Plate(Ip). Materials and Methods: Radiograms were taken by Heliodent MD(Siemens Co.. Germany) with the image plate for adult. Cu-step wedge as reference material. and three pieces of dry mandibular bone. Image analysis was performed by single color enhancement. density measurement with histogram. The relationship between the exposure conditions and the distribution of the pixel values of the image. the variation of pixel values of each step of Cu-step wedge at two different area and Cu-equivalent value of three pieces of dry mandibular bone measure by the conversion equation. Results: There was no linear relationship between the exposure condition and the average pixel value of the image. of which the distribution was not even. The pixel value differences between the center portion and the periphery were ranged from 60 to 70 in vertical plane and from 15 to 26 in horizontal plane. Two plot profile formed at two different areas of the Cu-step wedge were different. The measured Cu-equivalent values showed the discrepancy among the times of measurement. Conclusion: As above results. Image Plate(Ip) of Digora system/sup (R)/ showed the limitation as the quantitative image. The physical property of IP was expected to need to be compensated for the quantitative evaluation of the bone or others

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An Overview of Bootstrapping Method Applicable to Survey Researches in Rehabilitation Science

  • Choi, Bong-sam
    • Physical Therapy Korea
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    • v.23 no.2
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    • pp.93-99
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    • 2016
  • Background: Parametric statistical procedures are typically conducted under the condition in which a sample distribution is statistically identical with its population. In reality, investigators use inferential statistics to estimate parameters based on the sample drawn because population distributions are unknown. The uncertainty of limited data from the sample such as lack of sample size may be a challenge in most rehabilitation studies. Objects: The purpose of this study is to review the bootstrapping method to overcome shortcomings of limited sample size in rehabilitation studies. Methods: Articles were reviewed. Results: Bootstrapping method is a statistical procedure that permits the iterative re-sampling with replacement from a sample when the population distribution is unknown. This statistical procedure is to enhance the representativeness of the population being studied and to determine estimates of the parameters when sample size are too limited to generalize the study outcome to target population. The bootstrapping method would overcome limitations such as type II error resulting from small sample sizes. An application on a typical data of a study represented how to deal with challenges of estimating a parameter from small sample size and enhance the uncertainty with optimal confidence intervals and levels. Conclusion: Bootstrapping method may be an effective statistical procedure reducing the standard error of population parameters under the condition requiring both acceptable confidence intervals and confidence level (i.e., p=.05).

Effect of Regularly Spine Strength Exercise on Lumbar Muscle Strength and Balance Ability in Teenager with Tutor (교사와의 상호작용을 통한 주기적인 척추운동이 청소년의 요부근력과 균형 감각에 미치는 영향)

  • Goo, Bongoh;Moon, Hyunju;Cho, sunghak
    • Journal of The Korean Society of Integrative Medicine
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    • v.3 no.2
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    • pp.55-61
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    • 2015
  • Purpose: The purpose of this study was to investigate the effect of regularly strength exercise of spine in teenagers with tutor. Method: Study subjects were 24 middle school students. They were arranged to 2 groups(n=12, respectively). Then experimental group did regularly strength exercise of spine as the handout maneuver during 50min/day and 1day/week in 8 weeks with tutor, but control group did regularly exercise of spine as same maneuver without tutor. For muscle strength of both extensor and flexor of lumbar, the balancing ability and weight distribution index were measured before and after the intervention. Results: For muscle strength of both extensor and flexor of lumbar, there was not significant differences after the intervention, but both flexor and extensor increase mean value of muscle strength than control group. For balancing ability and weight distribution index, there were not significant difference after intervention(p>.05), but experimental group show a tendency to decrease in a few position than control group. Conclusion: When teenagers regularly exercise for spine strengthening for a long time with tutor, it may be increased muscle strength of lumbar and trunk balance.

Numerical simulations of interactions between solitary waves and elastic seawalls on rubble mound breakwaters

  • Lou, Yun-Feng;Luo, Chuan;Jin, Xian-Long
    • Structural Engineering and Mechanics
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    • v.53 no.3
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    • pp.393-410
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    • 2015
  • Two dimensional numerical models and physical models have been developed to study the highly nonlinear interactions between waves and breakwaters, but several of these models consider the effects of the structural dynamic responses and the shape of the breakwater axis on the wave pressures. In this study, a multi-material Arbitrary Lagrangian Eulerian (ALE) method is developed to simulate the nonlinear interactions between nonlinear waves and elastic seawalls on a coastal rubble mound breakwater, and is validated experimentally. In the experiment, a solitary wave is generated and used with a physical breakwater model. The wave impact is validated computationally using a breakwater - flume coupling model that replicates the physical model. The computational results, including those for the wave pressure and the water-on-deck, are in good agreement with the experimental results. A local breakwater model is used to discuss the effects of the structural dynamic response and different design parameters of the breakwater on wave loads, together with pressure distribution up the seawall. A large-scale breakwater model is used to numerically study the large-scale wave impact problem and the horizontal distribution of the wave pressures on the seawalls.

Behavior of Dry-stone Segmental Retaining Wall Using Physical Modeling and Numerical Simulation (모형시험과 수치해석을 이용한 조적식 석축옹벽의 거동 특성)

  • Kim, Seong-Su;Mok, Young-Jin;Jung, Young-Hoon
    • Journal of the Korean Geotechnical Society
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    • v.27 no.9
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    • pp.25-36
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    • 2011
  • The behavior of the dry-stone masonry retaining structure has been investigated via physical model test and numerical simulation. In the model test, the digital image analysis using PIV technique was employed to measure horizontal displacements in the backfill soils and retaining blocks. For finite element numerical analyses, the commercial code, ABAQUS, was used. The horizontal displacements observed in the model test showed that the development of the failure surface is progressive. Numerical results showed that in most cases horizontal earth pressure is distributed similarly to a conventional Rankine’s distribution. However, lower values of the internal friction angle of the backfill soils and interface friction angle in the front blocks produce irregularly nonlinear distribution of the horizontal earth pressure.

Analysis of physical properties of high-performance concrete using domestic low-cost silica fume (국산 저가형 실리카퓸을 이용한 고성능 콘크리트의 물리적 특성 분석)

  • Kim, Sang Do;Yun, Kyung Ku;Ham, Seung Yeon;Lee, Kyeo Re
    • Journal of Industrial Technology
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    • v.37 no.1
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    • pp.32-36
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    • 2017
  • In this study, as part of a research on the development of economical high-performance concrete with high strength and high quality, the physical properties of high-performance concrete were analyzed by substituting a certain amount of low-cost domestic silica fume exempted from the re-importation type distribution structure of the domestic production and the existing high-priced silica fume distribution structure. Performing tests to identify the physical properties of the fresh and hardened concrete and durability analogy of the concrete which use low-cost domestic silica fume and imported silica fume, the chloride ion penetration resistance test result showed that the strength difference between the low-cost silica fume and the imported silica fume is not big but the strength of the low-cost silica fume was measured higher than the imported silica fume. The chloride ion penetration resistance of all variables was measured as "very low". Since the low-cost domestic silica fume can be used as a high-performance admixture of concrete, the results suggest that it is possible to produce a more economical high-performance concrete.

Effect of Fines Distribution on Press Dewatering and Physical Properties of Multi-ply Sheet

  • Lee, Hak-Lae;Youn, Hye-Jung;Kang, Tae-Young;Choi, Ik-Sun
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.40 no.5
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    • pp.36-41
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    • 2008
  • Multi-ply sheet forming has many advantages including the possibility of using wide range of materials in a given structure, lowering production cost, making higher grammage products and so on. But, incorrect structure of sheet makes flow resistance higher so that it shows poor dewatering in press section. One of major factors that affect sheet structure and dewatering property is fines content in each layer. We, therefore, examined the press dewatering of multi-ply sheet that has the different fines content in each layer and the effect of fines distribution on physical properties of sheet to find a technology for optimum utilization of raw materials. In case of two layered sheet, the sheet which was composed of layers with the different flow resistance showed higher dewatering rate than one which has the same flow resistance. And the more difference in fines content for layers existed, the more dewatering occurred. For three layered sheets, dewatering is mainly dependent on fines content of bottom layer. Strength properties were affected by dewatering degree and multi-ply sheet structure.