• Journal of Life Science
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• v.15 no.3 s.70
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• pp.486-491
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• 2005

Physical activity can improve sensorimotor recovery after peripheral nerve injury. Growth-associated protein 43 (GAP-43) is highly correlated with neuronal development and axonal regeneration and present in large quantities in the axonal growth cone. Using immunofluorescene staining and anterograde and retorgrade techniques, we identified enhanced axonal regrowth in distal stump of the sciatic nerve 3-14 days after crush injury in rats with treadmill training. We also carried out western blot to investigate GAP-43 protein expression in injured sciatic nerve. GAP-43 protein levels were highly induced in the injured sciatic nerve 3, 7 and 14 days compared with sedentary group. Thus, the present data provide a new evidence that treadmill training promoted axonal re-growth after injury and increased GAP-43 protein levels in the regenerating nerve.

• The Journal of the Korea Contents Association
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• v.21 no.5
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• pp.561-580
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• 2021

This study analyses the historical and cultural streets at Pinggang Road in the city of Suzhou, by understanding the development and conservation of the area, and uses the following ways to investigate its development, re-organization, and current state. This paper comprehensively compares, collates and investigates 4 different historical and cultural areas in Insadong and Samcheong-dong in South Korea, and South Luogu Lane in China. From initial research and analysis, this paper gathers the cultural, economic, and societal perspectives as non-physical measures, and spatial structure, road structure, and building maintenance as physical factor framework. It is significant in that it can provide an evaluation model for the preservation and regeneration of historical and cultural streets by presenting the viewpoint of complex development of non-physical and physical elements in Pyeonggang-ro. In addition, it is necessary to conduct optimization and specific research on insufficient areas, such as maintenance and development of programs and signature systems for visitors, and continuous development of historical and cultural network platforms by combining on-site surveys. Basic data should be provided for reference on the street.

• Journal of the Korean Institute of Landscape Architecture
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• v.47 no.6
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• pp.53-66
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• 2019

The purpose of this study was to suggest indicator-based selection and improvement plans for evaluating urban regeneration projects. First, we selected the indicators by conducting expert surveys and analysis of the responses received. Additionally, using the selected indicators, we analyzed the residents' opinions in Wongogae Village, where urban regeneration projects were in progress. Based on these, we suggested a plan to improve Wongogae Village. According to the study, we classified the urban regeneration evaluation indicators into 'Physical environment', 'Social environment' and 'Economic environment' according to their characteristics. We selected urban regeneration evaluation factors through the first expert survey and MCB analysis. As a result, we selected six factors for the 'Physical environment' category: 'Traffic and pedestrian environment', 'Residential (housing) environment', 'Safety and security environment', 'Greenspace', 'Landscape improvement' and 'Public space', In the 'Social environment' category, four factors were chosen: 'Resident participation', 'Community activation', 'Role of the local government and support centers' and 'Resident education' while for the 'Economic environment' category three factors were selected: 'Local economic revitalization', 'Creating an economy-based environment', 'Job creation'. Next, we conducted a second expert survey and carried out an AHP analysis using the selected evaluation factors to derive the overall weight for each. Among the evaluation factors for urban regeneration, the 'Residential (housing) environment' has the highest weighted value of 0.108, followed by 'Local economic revitalization' and 'Resident participation'. Lastly, the analysis of the residents' opinions of Wongogae Village using the urban regeneration evaluation factors, Parking environment', 'Maintenance of old houses and living environment', 'Environment for founding town and social enterprises', 'Improve commercial and business environment', 'Maintain and activate existing business' and 'Vitalizing small regional economies such as domestic handicrafts and side-job' had high overall importance, but low satisfaction, which means that it is necessary to improve the focus. Therefore, in order to improve the urban regeneration project in villages, it is necessary to improve the parking environment by expanding public parking lots, eliminate close houses, and idle lands, or open a school playground in the village for the residents. In addition, it is essential to encourage economic activities, such as fostering village enterprises and social enterprises in connection with cooperatives and allow for the selling of the products through resident activities, such as neighboring markets.

• Ceramist
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• v.21 no.3
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• pp.216-232
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• 2018

The average life span is over 80 years of age, and various biomaterials have being studied. Many research institutes and companies around the world have been commercializing bioactive glass through R&D, however, there is not much research in Korea. Most bioactive glass is applied to bone regeneration in powder form due to its excellent bio-compatibility. Recently, new applications such as scaffolds for tissue engineering and nerve regeneration have been found in composite form. The global market size is not as large as US $ 556 million in 2019, but the growth rate is very high at a CAGR of 14.35 %. This field is waiting for the challenge of new researchers.

• Journal of the Korean Professional Engineers Association
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• v.42 no.6
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• pp.31-35
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• 2009

This paper aims to draw out the practical lessons for City Brand as aspect of urban spatial by urban regeneration project in Korea. Image of the City and City Brand is the most important element for the competitiveness of modern cities. This paper discusses the guide line or strategy of City Brand, its current status in Korea. It also examines the present Urban Regeneration in Korea, identifies the problems encountered in implementation, and suggests the solutions for strengthening urban competitiveness such as a City Brand. Also it emphasized that well planned invisible and physical environments, including story and land-mark facilities, are also crucial in making City Brand more attractive and competitive.

• The Journal of Korean Physical Therapy
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• v.13 no.3
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• pp.603-611
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• 2001

This study was performed. using EGF, to observated the effect of GaAIAs laser on wound model induced designedly in lumbar region. The results of this study were as following: 1. In expression of EGF which used marker of wound healing, laser irradiating group made EGF to more induce significantly than laser non-irradiating group at 3 days. 2. EGF immunoreactivity in epidermis were increased markedly 3 days after wound, and increased gradually from 1 day to 2 days in wound which is laser irradiation. Therefore, EGF immunoreactivity which increased after wound with GaAIAs laser irradiation indicate that GaAIAs laser have wound healing effect. This study also can become a part of scientific evidence on electrotherapy through measuring quantitively effects of GaAIAs laser in wound

• The Journal of the Korea Contents Association
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• v.16 no.2
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• pp.129-142
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• 2016

This study evaluates the sectoral effects of the regeneration of the idle space and aims to analyze the impact relationship and structure with the quality of residents's life and local economy revitalization. this study verifies the 8 hypotheses from total 11 ones through the PLS structural equation model and suitability test for setting the hypothesis and statistical significance test. The results can be summarized into 3 parts. First, If physical, social and cultural aspects should be considered, Regeneration of idle space could meet the 2 pasts such as quality of residents life and local economy revitalization at the same time. Secondly, the regeneration of idle space from environmental aspect should be led by the local government and let it's effect leaded to local economy revitalization through the collaboration of private and public sector. Finally, it should promote the quality of resident's life and let the satisfaction linked to cyclical effects with local economy revitalization. This study has an significance that it provides the theoretical basis for regeneration of idle space and it is an empirical study for impact structure model.

• Plant Biotechnology Reports
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• v.3 no.3
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• pp.175-182
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• 2009

Simple, reproducible, high frequency, improved plant regeneration protocol in Eastern Cottonwood (Populus deltoides) clones, WIMCO199 and L34, has been reported. Initially, aseptic cultures established from axillary buds of nodal segments from mature plus trees on MS liquid medium supplemented with $0.25mg\;1^{-1}$ KIN and $0.25mg\;1^{-1}$ IAA. Nodal and internodal segments were found to be extra-prolific over shoot apices during course of aseptic culture establishment, while $0.25mg\;1^{-1}$ KIN concentration played a stimulatory role in high frequency plant regeneration. Diverse explants, such as various leaf segments, internodes, and roots from in vitro raised cultures, were employed. Direct plant regeneration was at high frequency of 92% in internodes, 88% in leaf segments, and 43% in root segments. This led to the formation of multiple shoot clusters on established culture media with rapid proliferation rates. Many-fold enhanced shoot elongation and growth of the clusters could be achieved on liquid MS medium supplemented with borosilicate glass beads, which offer physical support for proliferating shoots leading to faster growth in comparison to semi-solid agar or direct liquid medium. SEM examination of initial cultures confirmed direct plant regeneration events without intervening calli. In vitro regenerated plants induced roots on half-strength MS medium with $0.15mg\;1^{-1}$ IAA. Rooted 5- to 6-week-old in vitro regenerated plants were transferred into a transgenic greenhouse in pots containing 1:1 mixture of vermicompost and soil at $27{\pm}2^{\circ}C$ for hardening and acclimatization. 14- to 15-week-old well-established hardened plants were transplanted to the field and grown to maturity. The mature in vitro raised poplar trees exhibited a high survival rate of 85%; 4-year-old healthy trees attained an average height of 8 m and an average trunk diameter of 25 cm and have performed well under field conditions. The regeneration protocol presented here will be very useful for undertaking genetic manipulation, providing a value addition to Eastern Cottonwood propagation in future.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.2
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• pp.819-828
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• 2021

In urban regeneration projects, the core projects define the characteristics of the project site and contribute to the highest project cost and drive the project forward. The purpose of this study was to identify the current status and characteristics of the project as a priming project for urban regeneration and to seek desirable alternatives in the future project process. For this purpose, the case of urban regeneration projects in the Chungcheong region was targeted. The results showed that the core projects for each case consisted mainly of projects to develop physical facilities on a relatively large scale. Securing large-scale complex base space and constructing public parking lots are planned as key projects. In addition, based on the cost composition of the priming project, the core project accounted for approximately 80 % of the total project, and the project cost between linked projects does not appear to be relatively well linked in both public and private investment sectors. These findings are expected to help promote substantial urban regeneration projects and enhance efficiency by using them as basic data for urban regeneration projects in the future.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.1
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• pp.145-152
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• 2007

Following CNS injury, inhibitory influences at the site of axonal damage occur. Glial cells become reactive and form a glial scar, gliosis. Astrocyte-rich gliosis relates with up-regulation of GFAP and CD81, and eventually becomes physical and mechanical barrier to axonal regeneration. It is postulated that the astrocytic reaction is absent, regeneration of axons can occur. And it was reported that treatment with anti CD81 antibodies enhanced functional recovery in the rat with spinal cord injury. So in this current study, the author investigated the effect of the water extract of Persicae Semen on the regulation of GFAP and CD81 that increase when gliosis occurs. Persicae Semen decreased the expression of GFAP and CD81 in astrocyte cell by ELISA method. Persicae Semen decreased the RNA expression of CD81 and GFAP. The proteins that separate in whole cell were analaysed by western blot, and the expression of GFAP and CD81 was decreased. In vivo, rats brains were peformed cortical stab wound, the water extracts of Persicae Semen were injected for 7 days, 30 days. As a result, GFAP and CD81 expression were decreased in immunohistochemistry. These findings demonstrate that Persicae Semen decreases GFAP and CD81 expression. Accordingly, Persicae Semen could be a candidate for promotion of axon regeneration after CNS injury.