• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.26 no.3
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• pp.36-53
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• 2013

Objectives : The purpose of this study is to investigate the effects of DOGO phreatic water containing sulphur on Atopic Dermatitis in NC/Nga mouse. Methods : We made DOGO phreatic water removed sulphur using Twin Alternating Sulfate Eater. After making atopic dermatitis caused by sensitizing NC/Nga mouse to DNCB(dinitrochlorobenzene), we made mouse swim in tanks each filled with distilled water, tap water, DOGO phreatic water(contain sulphur), DOGO phreatic water(remove sulphur) for 30minutes everyday. 3weeks later, we analyzed skin clinical score, total IgE levels(by ELISA), WBC differential counting(Neutrophils, Monocytes), absolute cell number of $Neutrophil^+Gr-1^+$, CCR3 mRNA expressions(by Real-time PCR), IL-4, IFN-${\gamma}$ production levels(by ELISA), histologic test(by H&E staining, toluidine blue staining). Results : The results of making NC/Nga mouse induced atopic dermatitis swim in tanks filled with DOGO phreatic water(contain sulphur) are as follows. 1. Skin clinical scores were decreased significantly in comparison to control group. 2. Total IgG levels were decreased significantly in comparison to control group. 3. WBC differential counting(Neutrophils, Monocytes) were decreased significantly in c.mparison to control group. 4. Absolute cell number of $Neutrophil^+Gr-1^+$ were decreased significantly in comparison to control group. 5. CCR3 mRNA expressions were decreased significantly in comparison to control group. 6. IL-4, IFN-${\gamma}$ production levels were decreased significantly in comparison to control group. 7. The epithelial tissue thickness, leucocytes infiltration, erythema, edema, excoriation, scaling, mast cells infiltrations in dorsal skin were decreased in comparison to control group. Conclusions : These results indicate that DOGO phreatic water(contain sulphur) can be used for helping treat atopic dermatitis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.27 no.4
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• pp.141-157
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• 2014

Objectives : The purpose of this study is to investigate the effects of DOGO phreatic water containing germanium on Atopic Dermatitis in NC/Nga mouse. Methods : We made DOGO phreatic water added germanium. After making atopic dermatitis caused by sensitizing NC/Nga mouse to DNCB(dinitrochlorobenzene), we made mouse swim in tanks each filled with distilled water, tap water, DOGO phreatic water, DOGO phreatic water(added germanium) for 30minutes everyday. 3weeks later, we analyzed skin clinical score, total IgE levels(by ELISA), WBC differential counting(Neutrophils, Monocytes), absolute cell number of $Neutrophil^+Gr-1^+$, CCR3 mRNA expressions(by Real-time PCR), IL-4, IFN-${\gamma}$ production levels(by ELISA), histologic test(by H&E staining, toluidine blue staining). Results : The results of making NC/Nga mouse induced atopic dermatitis swim in tanks filled with DOGO phreatic water(contain germanium) are as follows. 1. Skin clinical scores were decreased significantly in comparison to control group. 2. Total IgG levels were decreased significantly in comparison to control group. 3. WBC differential counting(Neutrophils, Monocytes) were decreased significantly in comparison to control group. 4. Absolute cell number of $Neutrophil^+Gr-1^+$ were decreased significantly in comparison to control group. 5. CCR3 mRNA expressions were decreased significantly in comparison to control group. 6. IL-4, IFN-${\gamma}$ production levels were decreased significantly in comparison to control group. 7. The epithelial tissue thickness, leucocytes infiltration, erythema, edema, excoriation, scaling, mast cells infiltrations in dorsal skin were decreased in comparison to control group. Conclusions : These results indicate that DOGO phreatic water(contain germanium) can be used for helping treat atopic dermatitis.

• Journal of the Korean Geotechnical Society
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• v.21 no.7
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• pp.43-54
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• 2005

Tunnelling in a water bearing soil may cause draw-down of ground water table. Modelling of this problem requires considering the change of phreatic surface including the stress constitutive relationship for an unsaturated soil. However, it is normally assumed that ground water is confined. Numerical formulation of coupled behavior considering phreatic surface is described and implemented into computer program. Influence of unconfined flow on tunnel and ground is thoroughly investigated and compared with that of confined flow condition. It is identified that ground and lining behaviour below phreatic surface is almost the same as that under confined flow conditions, however, there is considerable difference in ground behaviour above phreatic surface. It is generally concluded that the assumption of confined flow is acceptable in terms of lining design.

• Magazine of the Korean Society of Agricultural Engineers
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• v.43 no.2
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• pp.78-84
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• 2001

The daily streamflow in the Yaluhe watershed located in the north-eastern part of China was simulated by DAWAST model and the water balance parameters of the model were calibrated by simplex method. Model verification tests were carried out. The range of root mean square error was 0.34∼1.50mm, that of percent error in volume was -16.9∼-62.0% and that of correlation coefficient was 0.727∼0.920. DAWAST model was revised to consider the phreatic evaporation from the ground water in the frozen soil by adjusting soil moisture content in the unsaturated layer at the end of the melting season. The results of estimation of the daily streamflow by the revised model were statistically improved, that is, the range of root mean square error was 0.31∼1.49mm, that of percent error in volume was -11.7∼-12.1%, and that of correlation coefficient was 0.810∼0.932. The accuracy of DAWAST model was improved and the applicability of DAWAST model was expanded to the frozen region.

• The Journal of Korean Medicine
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• v.38 no.4
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• pp.62-81
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• 2017

Objectives: As interests in the beauty of skin is growing continuously, more people are focusing on white and clean skin. Melanin is the major factor that determines skin color. The abnormal concentration of melanin causes various skin diseases such as vitiligo, freckles, and melasma. This study investigated the inhibitory effect of Eriobotryae Folium extracts (EF) with phreatic water (PW) on the melanin synthesis. Methods: The effect of EF on melanin synthesis was evaluated by using mouse melanoma cells (B16F10). To define the mechanisms, real-time PCR and western blot were used. We also evaluated the inhibitory effects of EF and PW on melanin synthesis by using HRM-2 melanin-possessing hairless mice. After UVB irradiation, melanin differences between the skin parts that were treated and untreated with EF and PW. Levels of mRNA were measured by real-time quantitative PCR and histological analysis of the dorsal skin was conducted by hematoxylin and eosin staining. Results: EF inhibited various mechanisms of melanogenesis, and the effect was increased when combined with PW. In vitro experiments have shown that EF inhibited the expressions of tyrosinase related protein-1 (TRP-1) mRNA, tyrosinase mRNA, microphthalmia-associated transcription factor (MITF) mRNA and the tyrosinase inhibitory activation, but it stimulated the extracellular regulated kinase (ERK) mRNA expression. In vivo experiments have shown that EF prevented melanogenesis in the mice dorsal skin and inhibited TRP-1 mRNA expression. Also these effects were increased when combined with PW. Conclusions: EF and PW might be a new and effective treatment for whitening and treating pigmentation of skin.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2002.04a
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• pp.237-242
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• 2002

This study is objected to assess the recharges of phreatic aquifers in the south Korea. The water level data of the national ground-water monitoring network were analysed by PCA(Principal Component Analysis), and classified to 8 types. The recharge were estimated by ‘water-level change method’ on basis of the classified types and compared with the previous methods(hydrograph separation methods) on basis of 4 river basins. The recharge were various type by type and site by site. But the recharge estimated by this study were consistent with that of the other studies.

• Journal of the Korean Geosynthetics Society
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• v.9 no.3
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• pp.77-85
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• 2010

The change of water level in reservoirs is an important factor causing failure of bank slopes, i.e. landslide. The water level of Three Gorges reservoir in China fluctuate between 145 m and 175 m, as a matter of flood control. During its normal operational state, the rate of water level fluctuation is supposed to range from 0.67 m/d to 3.0 m/d. Majiagou slope is located on the left bank of Zhaxi River, 2.1 km up from the outlet. Zhaxi River is a tributary of the Yangtze River within the Three Gorges area, of which the water level changes with the reservoir. At the back of Majiagou slope, a 20 m long and 3~10 cm wide fissure developed just after the reservoir water level rose from 95 m to 135 m in 2003. This big fissure was a full suggestion of potential failure of this slope. In this study, unsaturated-saturated seepage analyses were carried out to simulate the change of pore-water pressures in the bank slope subjected to the reservoir water level change. The obtained pore-water pressures were then used to evaluate the change in factor of safety (FS) with reservoir water level. It was found that the phreatic line showed a delayed response with respect to the change of the reservoir water level, because the seepage through soil layer was generally slower than water flows itself. During the rising and drawdown process, the phreatic lines take the shapes of concave and convex, respectively. And the fluctuation of reservoir water level just affected the front part of the bank slope, but had little influence on the back of the slope.

• Environmental Engineering Research
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• v.15 no.2
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• pp.85-91
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• 2010

Romania aims to adopt and implement the European Union's legislation, also including that for the field of water management. Like other countries, groundwater in Romania is locally polluted from point sources, such as leaking landfills, as well as from diffuse pollution sources, include fertilizers, pesticides and leakages from sewers, in urbanized areas. Diffuse pollution can also occur indirectly, by over-exploitation of groundwater wells, resulting in salt water intrusion, as well as from mining and exploitation of mineral aggregates. Romania has quite an intensive monitoring scheme to measure groundwater quality in phreatic and confined aquifers. The purpose of the work resumed in this paper was to derive natural background levels (NBL) for groundwater in order to distinguish the natural elevated concentrations of some substances (natural phenomena) from point and diffuse pollution (anthropogenic phenomena). Based on these NBLs, threshold values (TV) for groundwater will be set according to the requirements of the European Water Framework Directive and the related Groundwater Directive. This paper describes the results of a study for the derivation of NBL and TV in a pilot Groundwater Body. Also, the process and draft results for extrapolating this work for all Romanian groundwater bodies is explained, as well as points for future consideration with respect to monitoring and management.

• Journal of the Korean GEO-environmental Society
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• v.17 no.7
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• pp.5-13
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• 2016

This research is focused on the seepage behavior of embankment which had the weak zone with big permeability. The distributed TDR (Time Domain Reflectometer) and point sensors such as settlement gauge, pore water pressuremeter, vertical total stressmeter, and FDR (Frequency Domain Reflectometer) sensor were used to measure the seepage characteristics and embankment behavior. Also, the measured data were compared to the data of 2-D and 3-D numerical analysis. The dimension of model embankment was 7 m length, 5 m width and 1.5 m height, which is composed of fine-grained sands and the water level of embankment was 1.3 m height. The seepage behavior of measuring and numerical analysis were very similar, it means that the proper sensing system can monitor the real-time safety of embankment. The result by 2-D and 3-D numerical analysis showed similar saturation processing, however in case of weak zone, the phreatic lines of 2-D showed faster movement than that of 3-D analysis, and finally they converged.

• Proceedings of the Korean Geotechical Society Conference
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• 2006.03a
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• pp.75-85
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• 2006

In recent geotechnical engineering, geothermal approach has been on the horizon to deal with geoenvironmental issues, freezing and thawing problems, and seepage phenomenon in dams and embankments. In this study, geothermal characteristic through inner body of dams and its influence on the seepage flow were experimented by lab test and field instrumentation. Also, one of up-to-date temperature monitoring technique, called as multi-channel thermal line sensing, was evaluated its availability. As a result of lab test, it is found that the seepage flow has influence on the geothermal characteristic and a potential of finding phreatic line and seepage fluctuation could be possible by continuous temperature monitoring using thermal line sensing skills. These kine of geothermal information could be available to the modelling of water geo-structure interaction. Out of short-term field tests, clear water table and temperature distribution of a dam were easily found through temperature monitoring in holes located near a reservoir and holes within a depth of constant temperature layer. However, it is also found that the geothermal flow and finding seepage line could not be easily understandable through multi-channel temperature monitoring because of the existence of constant temperature field, thermal conductivity of soils and rocks, and unsaturated characteristics of geo-material. In this case, long-term geothermal monitoring is recommended to find sudden fluctuation of seepage line and amount of leakage.