• Title/Summary/Keyword: Phenolic components

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Inhibition of Monoamine Oxidase B by Cigarette Smoke Constituents

  • Lim, Heung-Bin;Sohn, Hyug-Ok;Lee, Young-Gu;Moon, Ja-Young;Kang, Young-Kook;Kim, Yong-Ha;Lee, Un-Chul;Lee, Dong-Wook
    • Journal of the Korean Society of Tobacco Science
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    • v.19 no.2
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    • pp.136-144
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    • 1997
  • Cigarette smoking is known to suppress both 1-methy14-phenyl-155,Ltetrahydropy-ridine (MPTP)-induced parkinsonism and idiopathic Parkinson's disease (PD). However, the precise mechanism underlying its protective action against PD is not clearly elucidated yet. In order to find possible clue on the mechanism of protective action of smoking, we investigated the inhibitory effect of cigarette smoke components on rat brain mitochondria1 monoamine oxidase B (MAO-B), responsible enzyme for the activation of MPTP to its toxic metabolitesr and identified the components having an inhibitory potency on this enzyme from cigarette smoke. Total 31 eligible constituents including nicotine were selected from cigarette smoke condensates via solvents partitioning and silica gel chromatographic separation, and inhibitory potencies of 19 components on MAO-B were determined. Hydroquinone and methylcatechol, the phenolic components, showed the strongest inhibitory potencies on MAO-B activity in the components tested. 3,4-Dihydroxybenzylamino, myosmine and indole in basic fracton, eugenol in phenolic fraction, and farnesol in neutral fraction also inhibited the enzyme activity dose-dependently. Among tobacco alkaloids tested only myosmine was effective for the inhibition of this enzyme. These results suggest that the decrease in MAO-B activity by such components derived from cigarette smoke seems to be related to the suppression of MPTP-induced neurotoxicity and to the less incidence of Parkinson's disease in smokers than in nonsmokers.

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Comparison of Pyrolytic Components in lamina and Midrib of Flue-Cured Tobacco Leaves

  • Lee, Jae-Gon;Jang, Hee-Jin;Kwag, Jae-Jin;Lee, Dong-Wook
    • Journal of the Korean Society of Tobacco Science
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    • v.22 no.2
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    • pp.176-183
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    • 2000
  • This study was conducted to compare the volatile components of lamina(cutter group) and midrib of flue-cured tobacco leaves by two analytical methods, Curie-Point pyrolysis and Purge & Trap headspace technique. The pyrolysis of lamina and midrib part of tobacco leaves was performed at the temperature of $330^{\circ}C$, $650^{\circ}C$, and $920^{\circ}C$ by Curie-Point Pyrolyzer, and 33 compounds were identified in the pyrolyzates by GC/MSD. The composition of the components identified showed a quite difference between lamina and midrib. However, the amount of the pyrolyzed products from the both of lamina and midrib was increased with temperature increase except that of acetic acid, furfural, and nicotine. The content of phenolic compounds including phenol, 4-methyl phenol, and 3-methyl phenol was higher in midrib than in lamina, while that of furan compounds such as 2,3-dihydrobenzofuran, 5-hydroxymethyl furfural, was high in lamina. Interestingly, acetamide, 2-propenamide and 3-acetoxy pyridine were not defected in the pyrolyzates of lamina. By Purge & Trap headspace technique, 28 volatile components were identified in both lamina and midrib. The composition of the identified compounds and their chromatograpic patterns also showed the complete difference between the two. The content of solanone, $\beta$-damascone, $\beta$-damascenone, and megastigmatrienones, key components of tobacco aroma, was much higher in lamina than in midrib. The results indicate that lamina contains much more carbonyl compounds known to enhance the smoke taste of cigarette, whereas midrib takes nitrogenous and phenolic compounds, which are known to cause a deteriorate effect of smoke such as irritation.

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Characteristics of Useful Components in the Leaves of Baechohyang(Agastache rugosa, O. Kuntze) (배초향 잎의 유용성분과 특성)

  • 최갑성;이홍열
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.28 no.2
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    • pp.326-332
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    • 1999
  • In order to develope useful components and to apply in food additives, various components in the leaves of baechohyang were determined according to picking date. Moisture and ash were reached to 74~82%, 1.5~3.4%, respectively, and major sugars were fructose, glucose, sucrose, and maltose. Glutamic, aspartic acid, and leucine constituted the main component amino acids and their contents were relatively higher in the samples of summer and young leaves. Among free amino acids, histidine showed the highest components and methionine were the lowest. Potassium, calcium, and sodium were main mineral components. The content of ascorbic acid were 6.6~9.2mg% and seasonal variations were negligible. Muture leaves contained more polyphenols as much as 108~181mg% and the amount of bound fractions were much more. Periodic evaluation of phenolic compounds were made and major components of bound fractions were caffeic, syringic, and ferulic acid.

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The Properties of Polyurethane Toughened-Phenolic Resin and Wood Powder Composites (폴리우레탄으로 강인화한 페놀수지와 목분 복합체의 물성)

  • Son, Won-Keun;Park, Soo-Gil;Kim, Young-Churl;Shin, Dong-Keun
    • Applied Chemistry for Engineering
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    • v.9 no.2
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    • pp.238-242
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    • 1998
  • Wood powder filled phenolic resin composites of different composition were prepared and their mechanical properties were investigated for optimum conditions. The composites showed maximum mechanical strength when the phenolic resin content was 45 wt%. Polyurethane prepolymer(PU) was evaluated as a modifier of the phenolic resin composites. Blocking of the isocyanates in the PU with phenol was necessary for homogeneous mixing of raw materials for the components. Maximum mechanical strength of the PU modified composites was observed when the PU content was 5 wt%. It was found that the mechanical strength of the composites cured at $210^{\circ}C$ were higher than those of the composites cured at $150^{\circ}C$.

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Characteristics of Nutritional Components in Astringent Persimmons according to Growing Region and Cultivar (떫은감의 재배지역과 품종에 따른 영양성분 특성)

  • Bian, Lin-Lin;You, Su-Yeon;Park, Jeongjin;Yang, Soo Jin;Chung, Hyun-Jung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.44 no.3
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    • pp.379-385
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    • 2015
  • The nutritional components of astringent persimmons according to growing region (five different regions) and cultivar (Daebong and Bansi) were analyzed. The analyzed nutritional components were proximate compositions, insoluble and soluble dietary fibers, vitamin C, carotenes (${\beta}$-carotene and lycopene), free sugars (glucose, fructose, and sucrose), sugar alcohols (xylitol, sorbitol, and mannitol), minerals (Na, Mg, K, Ca, Mn, Fe, and Zn), organic acids (tartaric acid, malic acid, citric acid, and succinic acid), tannic acid, total phenolic compounds, and flavonoids. Daebong and Bansi, which are representative cultivars of astringent persimmons grown in Korea, exhibited significant differences in nutritional components. Insoluble dietary fibers, ${\beta}$-carotene, fructose, sucrose, mannitol, potassium, malic acid, succinic acid, and total phenolic compounds were present at higher levels in Daebong as compared to Bansi. On the other hand, Bansi was rich in moisture, crude protein, vitamin C, Ca, Mn, tartaric acid, and flavonoids. Nutritional components were highly influenced by growing region. Daebong grown in region A was greater in ${\beta}$-carotene, sorbitol, mannitol, zinc, and total phenolic compounds among the all other tested persimmons grown in five different regions. The crude protein, Na, Ca, Mn, tartaric acid, and flavonoids were highest in Bansi grown in E region.

Effects of Increase in Ratio of Phenolic Hydroxyl Function on Carbon Fiber Surfaces by Anodic Oxidation on Mechanical Interfacial Bonding of Carbon Fibers-reinforced Epoxy Matrix Composites (양극산화 처리에 따른 탄소섬유 표면의 페놀릭 하이드록실 관능기 비율의 증가가 에폭시기지 복합재료의 기계적 계면결합 특성에 미치는 영향)

  • Kim, Dong-Kyu;Kim, Kwan-Woo;Han, Woong;Song, Bhumkeun;Oh, Sang-Yub;Bang, Yun Hyuk;Kim, Byung-Joo
    • Applied Chemistry for Engineering
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    • v.27 no.5
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    • pp.472-477
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    • 2016
  • We studied the effects of anodic oxidation treatments of carbon fibers on interfacial adhesion of the carbon fibers-reinforced epoxy matrix composites with various current densities. The surface of treated carbon fibers was characterized by atomic force microscope (AFM), field emission-scanning electron microscope (FE-SEM), Fourier transform infrared spectroscopy (FT-IR), and X-ray photoelectron spectroscopy (XPS). The interlaminar shear strength (ILSS) of the composites was determined by a short beam shear test. This result showed that both the roughness and oxygen group of the carbon fibers surface increased in proportion to the current density. After anodic-oxidation-treated, the ILSS also increased as a function of the current density. In addition, the proportional relationship between ILSS and phenolic hydroxyl group was confirmed. The ILSS of the CF-2.0 sample increased by 4% compared to that of the CF-AS sample, because the anodic oxidation treatment increased the oxygen group and roughness on the carbon fibers surface, which leading to the improvement of the interfacial adhesion of the carbon fibers-reinforced epoxy matrix composites. Among these, the phenolic hydroxyl group which has the proportional relationship with ILSS is found to be the most important factor for improving the interfacial adhesion of the carbon fibers-reinforced epoxy matrix composites.

Alteration in Phenolic Compounds and Antioxidant Activities of Aronia melanocarpa Ethanol Extracts following Fermentation Using Different Strains of Leuconostoc mesenteroides to Develop Natural Antibiotic Alternative (항생제 대체 천연물질을 위한 아로니아 주정 추출물 개발에 있어 다양한 Leuconostoc mesenteroides 균주를 이용한 발효가 페놀계 화합물 및 항산화활성 변화에 미치는 영향)

  • Hwang, Joo Hwan;Kang, Ju Hui;Lee, Ki Hwan;Lee, Jae Hoon;Lee, Sang Moo;Kim, Nam Hyung;Kim, Joo Young;Kim, Eun Joong
    • Korean Journal of Organic Agriculture
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    • v.22 no.4
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    • pp.825-839
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    • 2014
  • Antioxidant activity is important for reducing oxidative stress that causes various metabolic disorders. Metabolic disorders are highly related to loss of productivity in livestock. Therefore, development of effective antioxidant compounds originating from plants is important for organic agriculture. Phenolic compounds in edible plants are regarded as major components relevant to antioxidant activity. The present study investigated the changes in antioxidant activity and phenolic compound profiles of Aronia (Aronia meloncarpa) by fermentation using different strains of Leuconostoc mesenteroides. A total of 5 strains of L. mesenteroides were used as starter cultures and their ${\beta}$-glucosidase activities were measured. A total of 6 experiment runs were prepared, one for control (uninoculated) and the others (inoculated) for treatments. For biological activity, antioxidant and antibacterial activities were measured. For phenolic compound profiling, TLC and HPLC analysis were performed. The strains of KACC12313 and KACC12315 showed greater enzyme activity than others. Treatment with KCCM35046 showed strong and broad antibacterial activity against to Listeria monocytogenes. Treatments with KCCM35046 and KACC12315 showed the highest total polyphenol content. The highest antioxidant activity was found in KACC12315 treatment. No remarkable alteration was found in thin layer chromatography (TLC) analysis. In phenolic compound profiling analysis, KCCM35046 showed notable alteration in compound area ratio compared to others and also showed the highest caffeic acid content. In chlorogenic acid, treatments with KCCM35046 and KACC12315 showed great content than others. Treatment with KACC12315 showed the greatest content of trans-ferulic acid. As a result of relative performance indexing analysis, L. mesenteroides KCCM35046 and KACC12315 were selected as the best strain for the fermentation of Aronia.

Phenolic Content, DPPH Radical Scavenging, and Tyrosinase Inhibitory Activities of Ecklonia cava Extracted with the Ultrasonic Wave Method (초음파 추출법에 의한 감태 추출물의 페놀성 화합물 함량, DPPH 라디칼 소거 활성 및 tyrosinase 저해 활성 분석)

  • Kim, So Jung;Kim, Donggiun;Park, Jongbum;Lee, Taek-Kyun
    • Journal of Life Science
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    • v.23 no.7
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    • pp.913-918
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    • 2013
  • The applicability of the ultrasonic wave method to the extraction of useful components from seaweeds was investigated. Extracts from freeze-dried Ecklonia cava powder were prepared with hot water ($65^{\circ}C$), water ($24^{\circ}C$), 50% ethanol, and 100% ethanol, and ultrasonic extraction was also performed. The content of phenolic compounds and the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and tyrosinase inhibitory activity of the extracts were analyzed, and differences in the data obtained by the ultrasonic extraction and the traditional extraction methods were compared. The phenolic content in the E. cava extract by ultrasonic extraction (142.80 mg/g) was approximately 14 times higher than the phenolic content in the hot water extract (10.03 mg/g). The DPPH radical scavenging and the tyrosinase inhibitory activities of the ultrasonic extract were approximately 4 times and 14 times higher than the hot water extracts, respectively. The correlation between the phenolic content and the DPPH radical scavenging activity ($R^2$=99.47) and between the phenolic content and the tyrosinase inhibitory activity ($R^2$=99.99) was very high. These results indicate that ultrasonic extraction is more suitable than traditional extraction for the extraction of useful components from E. cava.

Flavor Components in the Filefish Processing (말쥐치 가공중 향기성분에 관하여)

  • LEE Jong-Ho;CHOI Byeong-Dae;LEE Kang-Ho;LEE Kun-Tae;KIM Tae-Soo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.22 no.3
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    • pp.121-128
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    • 1989
  • Volatile compounds were collected by simultaneous distillation extraction and carbon dioxide method, and analyzed by GC and GC-MS. The neutral fraction obtained from the whole steam volatile concentrate 55 kinds of components, phenolic fraction had 4 kinds of components, basic fraction had 13 kinds of components and 10 kinds of components were in acidic fraction. Alcohols, propanols, butanols, octanols, dodecanols etc. and aldehydes, pentanals, hexanal, 2-methyl-1-propanal, heptenal etc. were highly increased after boiled and roasted. And these compounds were contributed to formation of filefish flavor. The molecular ion peak of phenolic fraction was generally appeared in the range 100 to about 160. From the basic fraction, 2-methylpyrazine, 2,5-dimethylpyrazine, 2-ethyl-3,5-di-methylpyrazine and 2-methylpyridine were identified. The contents of basic compounds and furans obtained from the neutral fraction were increased at the higher heating temperature. The flavor of acidic fraction was influenced by the low molecular as isovaleric and valeric acid.

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Pharmacological and Adverse Effects of Aloe vera

  • Lee, Kyoung-Rim;Yoo, Sun-Dong;Lee, Byung-Mu
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.149.1-149.1
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    • 2003
  • Active ingredients, therapeutic and adverse effects of Aloe vera were comprehensively investigated. Aloe vera contains active components. including sugars, proteins, lipids, vitamins, minerals, phenolic compounds and other several compounds like phthalate esters, gibberellin, lectin-like substances, lignin, saponins, salicylic acid and uric acid. (omitted)

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