• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.7 no.4
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• pp.36-48
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• 2008

Variable Message Signs(VMS) is one of the important subsystems of Intelligent Transportation Systems (ITS), which is useful for providing drivers with real-time information on traffic, roadway or weather conditions. In order to maximize the effectiveness of the VMS system, it is required to reflect drivers's preference on designing and operating the system. In this context, this study was conducted to develop strategies to deliver the messages in an efficient manner while many other previous studies focused primarily on the contents of the messages, from drivers's perspectives. Drivers's preference on message expression formats and message display orders were investigated through image analysis in the perspectives of a total of 40 subjects. With respect to message expression formats, drivers preferred Gulim or Dodum in font style, middle arrangement of the letters, pictogram combination as opposed to letters only, blank time less than 0.5 sec, appearing message in animation effect, messages in single phase, non-flashing message. In the matter of message display orders, drivers preferred to obtain link or traffic information in the lust place. Then, they desired to be informed of roadway condition and instructions or recommendations for drivers to cope with unexpected events among various messages for traffic condition.

• Journal of Korean Classical Literature and Education
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• no.38
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• pp.103-138
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• 2018

This study examines the modern succession, transformation and significance of enjoyment methods of classical literature (art) with a focus on the characteristics of those methods that appeared when the performances of the traditional era began to be displayed on the stage of the theaters in modern Seoul. The clues to the reasons for this type of enjoyment can be found in newspapers, magazine articles, and advertisements from the early 20th century. The emergence of stage theaters at the beginning of the modern era caused a sweeping change in the performance environment, including the fact that it was possible for all kinds of people to enjoy art beyond the existing socioeconomic hierarchies or barriers of status, that the performers were given employment through the theater, and that the audience had the tendency of the general public of an unspecified number because the audience was able to see the performances only by paying the viewing fee. The way of enjoying traditional performances also changed based on these new adaptations: the performances were sequential, show-oriented, and re-contextualized as public performances. It is significant that in the traditional era, performers and audiences had been segregated according to their status and a strict hierarchy; now, such cultural norms were breaking down in favor of a kind of equality. In addition, it was possible for the audience to experience sensory enjoyment, and theater brought about a new kind of popular consumer enjoyment of an artistic product. Of course, though, it is possible to look back and find problems related to the contemporary context, but the traditional performances, which were the main performances for the lower class, took the first place on the modern theater stage, and as a result, no one can deny that it became possible to move forward in the first phase of an era of public performance.

• The Journal of the Convergence on Culture Technology
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• v.5 no.4
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• pp.431-438
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• 2019

The present study was designed to investigate the chemopreventive effects of supercritical heat radish extracts with anti-constipation acitivity in loperamide-treated rats, on 1,2-dimethylhydrazine(DMH)-induced aberrant crypt foci(ACF) in rat colonic mucosa. Supercritical heat radish extracts was administered in the drinking water(3.2 mg/ml) during the initiation (for 12 weeks) or postinitiation phase(for 9 weeks) of DMH-induced carcicogenesis. Supercritical heat radish extracts coupled with DMH for 12 weeks decreased significantly total number of aberrant crypts(pre-neoplastic lesions) and the number of ACF to 35% and 30%, respectively. The number of ACF with more than four aberrant crypts (crypt multiplicity) was significantly reduced in the colon of rats receiving Supercritical heat radish extracts for 12 weeks. In the group receiving Supercritical heat radish extracts after post-initiation for 9 weeks, only the number of ACF with ${\geq}4$ abberant crypts significantly decreased. Supercritical heat radish extracts, given alone for 12 weeks, did not induced the development of ACF. These results indicate that Supercritical heat radish extracts possess chemopreventive effects on chemically induced rat colon carcinogenesis.

• Elastomers and Composites
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• v.40 no.2
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• pp.136-142
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• 2005

Liquid crystalline poly(allylsulfone) networks having $SO_2$ in a main chain and mesogens in a side chain were synthesized and their gas permeability and permselectivity were determined. The monomer II having two allyl groups on the each end group was able to form polymer networks by polymerization reaction, while the monomer I having only one allyl group was not. Molecular motion of the poly(allylsulfone) networks were retarded with increasing the cross-linking density, and the segmental motion of networks was developed enough to show isotropic phase transition. Gas permeabilities of poly(II-5 $01/I-OCH_3$ 99) were 2.58 baller for $O_2$ and 18.4 barrer for $H_2$. It means that hydrogen gas are 7 times more permeable than oxygen. Its permselectivities were high as 23.9 for ${\alpha}(H_2/N_2)$. The permselectivity was increased with increasing the cross-linking density. For example, ${\alpha}(H_2/N_2)$ was 36.8 in poly(II-5 $10/I-OCH_3$ 90), which was shown to be the highest value among these poly(allylsulfone) networks.

• Journal of the Korea Institute of Building Construction
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• v.21 no.5
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• pp.433-443
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• 2021

Value Engineering(VE) is an organized effort to create the most value through a functional analysis and creation of alternatives. Depending on the VE job plan, a VE Workshop must be performed in a certain place within a certain period of time. A VE Workshop, which is an organized activity that aims to create the best value through functional analysis and creation of alternatives, should be held in a certain place and at a scheduled time according to the VE job plan. In the Pre-Study, VE Study and Post-Study phases of VE, functional assessments, performance evaluations and idea evaluations are driven by variable management techniques and analysis methods, respectively. Generally, VE is executed for about 3 to 5 days in a particular place to create value. However, there are many problems associated with limiting all VE processes to a specific place and schedule. Moreover, in Korea, VE teams are required to finish all VE processes in a limited time because of the short duration of VE workshops, the necessity of which has been overlooked. Therefore, an efficient VE support system is required to resolve the problem of time and space limitations. In this study, a VE support system based on the Mobile environment was developed to support the VE Workshop process. This VE support system enables participants to review design documents, drawing sheets and all VE-related documents using mobile devices. After the Workshop, participants can conveniently rearrange the result(evaluation of function and ideas) at the workshop. Not only can the members of VE team can review the design documents, drawing sheet and all VE-related documents in the step before the workshop, but also the result(evaluation of function and ideas) of the workshop can be easily rearranged in the phase after the workshop under the developed supporting system using mobile devices.

• Korean Journal of Psychosomatic Medicine
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• v.29 no.2
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• pp.77-85
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• 2021

Breast cancer is the most prevalent oncological disease among women. Various psychosocial distress is common at the diagnosis, treatment, and posttreatment phase of breast cancer. For the treatment of breast cancer, not only medical treatment but also psychosomatic integrative care will be needed. Patients with breast cancer may lead to increased vulnerability to stress, adjustment disorder, anxiety disorder, and depressive disorder, and these psychiatric diseases and conditions are associated with recurrence or exacerbation of breast cancer. Psychosocial treatment of anxiety and depression could increase the quality of life of patients and decrease the recurrence and progression of breast cancer. In this article, we reviewed 5 clinical breast cancer survivorship guidelines focused on psychosomatic integrative care including psychosocial treatment and alternative treatment for psychosocial distress. Because 5 treatment guidelines were using various definitions of evidence, we confirmed evidence of various psychosocial treatments for patients with breast cancer based on the definition of evidence by the US Preventive Service Task Force (USPSTF) guideline. We also reviewed the effect size of psychosocial treatment for anxiety, depression, mood, and quality of life in patients with breast cancer. This article discusses the barrier to the delivery of psychosomatic integrative care and suggests integrative care planning for breast cancer. Multi-disciplinary teams, patient's needs assessment, information technology support, patient and caregiver engagement, planned periodic monitoring of psychosocial distress by a psychosomatic specialist or consultation-liaison psychiatrist are recommended as key features of a psychosomatic integrated care plan.

• Journal of Life Science
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• v.28 no.12
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• pp.1469-1476
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• 2018

Occurrence of the Warburg effect in solid tumors causes resistance to cancer chemotherapy, and targeting energy metabolisms such as aerobic glycolysis is a potential strategy for alternative treatment. Dichloroacetate (DCA), an inhibitor of pyruvate dehydrogenase kinase (PDK), shifts glucose metabolism from aerobic glycolysis to oxidative phosphorylation (OxPhos) in many cancers. In this study, we investigated the anticancer effect of DCA on a human anaplastic thyroid cancer (ATC) cell line, 8505C. We found that DCA selectively inhibits cell proliferation of the 8505C line but not of a normal thyroid line. In 8505C, the cell cycle was arrested at the G1/S phase with DCA treatment as a result of decreased antiapoptotic proteins such as $HIF1{\alpha}$, PDK1, and Bcl-2 and increased proapoptotic proteins such as Bax and p21. DCA treatment enhanced the production of reactive oxygen species which consequently induced cell cycle arrest and apoptosis. Interestingly, DCA treatment not only reduced lactate production but also increased the expression of sodium-iodine symporter, indicating that it restores the OxPhos of glucose metabolism and the iodine metabolism of the ATC. Taken together, our findings suggest that PDK inhibitors such as DCA could be useful anticancer drugs for the treatment of ATC and may also be helpful in combination with chemotherapy and radiotherapy.

• Geophysics and Geophysical Exploration
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• v.22 no.3
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• pp.132-148
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• 2019

Recently, safety and environmental concerns have become major social issues. Especially, a special underground-safety law has been made and enacted to prevent ground subsidence around construction sites. For environmental problems, several researches have started or will start on characterization of contaminated sites, in-situ environmental remediation in subsurface, and monitoring of remediation results. As a part of the researches, geophysical surveys, which have been mainly applied to explore mineral resources, geological features or ground, are used to characterize not only contaminated areas but also fluid flow paths in subsurface environments. As a basic study for the application of geophysical surveys to detect contamination in subsurface, this paper analyzes previous researches to understand changes in geophysical properties of contaminated zones by various contaminants such as leachate, heavy metals, and non-adequate phase liquid (NAPL). Furthermore, this paper briefly introduces how geophysical surveys like direct-current electrical resistivity, induced polarization and ground penetration radar surveys can be applied to detect each contamination, before analyzing case studies of the applications in contaminated areas by NAPL, leachate, heavy metal or nitrogen oxides.

• Tunnel and Underground Space
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• v.29 no.4
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• pp.262-279
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• 2019

In the engineering barriers of high-level radioactive waste disposal, gases could be generated through a number of processes. If the gas production rate exceeds the gas diffusion rate, the pressure of the gas increases and gases could migrate through the bentonite buffer. Because people and the environment can be exposed to radioactivity, it is very important to clarify gas migration in terms of long-term integrity of the engineered barrier system. In particular, it is necessary to identify the hydro-mechanical mechanism for the dilation flow, which is a very important gas flow phenomenon only in medium containing large amounts of clay materials such as bentonite buffer, and to develop and validate new numerical approach for the quantitative evaluation of the gas migration phenomenon. Therefore, in this study, we developed a two-phase flow model considering the mechanical damage model in order to simulate the gas migration in the engineered barrier system, and validated with 1D gas flow modelling through saturated bentonite under constant volume boundary conditions. As a result of numerical analysis, the rapid increase in pore water pressure, stress, and gas outflow could be simulated when the dilation flow was occurred.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.31 no.2
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• pp.50-61
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• 2019

The aspects of typhoon-induced surges were classified into three types at the Western coast, and their characteristics were examined. The typhoons OLGA (9907) and KOMPASU (1007) were the representative steep types. As they pass close to the coasts with fast translation velocity, the time of maximum surge is unrelated to tidal phase. However, typhoons PRAPIROON (0012) and BOLAVEN (1215) were the representative mild types, which pass at a long distance to the coasts with slow translation velocity, and were characterized by having maximum surge time is near low tide. Meanwhile, typhoons MUIFA (1109) and WINNIE (9713) can be classified into mild types, but they do not show the characteristics of the mild type. Thus they are classified into propagative type, which are propagated from the outside. Analyzing the annual highest high water level data, the highest water level ever had been recorded when the WINNIE (9713) had attacked. At that time, severe astronomical tide condition overlapped modest surge. Therefore, if severe astronomical tide encounter severe surge in the future, tremendous water level may be formed with very small probability. However, considering that most of the huge typhoons are mild type, time of maximum surge tends to occur at low tide. In case of estimating the extreme water level by a numerical simulation, it is necessary not only to apply various tide conditions and accompanying tide-modulated surge, but also to scrutinize typhoon parameters such as translation velocity and so on.