• Journal of Environmental Health Sciences
• /
• v.40 no.2
• /
• pp.114-126
• /
• 2014

Objectives: We aimed to develop a measurement method of five metabolites of trichloroethylene (TCE) in a concurrent biological sample, e.g., trichloroacetic acid (TCA), dichloroacetic acid (DCA), S-(1,2-dichlorovinyl) glutathione (DCVG), S-(1,2-dichlorovinyl)-L-cysteine (DCVC), and N-Acetyl-S-(1,2-dichlorovinyl)-L-cysteine (NAcDCVC) and to validate the method before application to pharmacokinetic study. Methods: TCE metabolites were simultaneously analyzed using high performance liquid chromatography coupled with electrospray ionization mass spectrometry (HPLC-ESI-MS/MS) with as little as 50 ${\mu}L$ of serum and urine. DCA, TCA and NAcDCVC were extracted with diethyl ether, while DCVC and DCVG were extracted by solid phase extraction. This method was validated according to the guidelines for bioanalytical method validation of the Korean National Institute of Toxicological Research. Then, we determined the five metabolites in five strains of mice at 24 hr after exposure to 1 g TCE /kg body weight. Results: The limits of detection for the five metabolites in biological samples ranged from 0.001 to 0.076 nmol/mL, which is comparable to or better than those previously reported. Most calibration curves showed good linearity ($R^2=0.99$), and between-batch variation was less than 20% expressing acceptable robustness and reproducibility. Using this method, we found TCA and DCA were detected in all test mice at 24 hr after the oral administration while NAcDCVC and DCVC were detected in some strains, which showed strain-dependent metabolism of TCE. Conclusions: The present method could provide robust and accurate measurements of major key metabolites of TCE in biological media, which allowed concurrent analysis of TCE metabolism for limited amounts of biospecimens.

• Journal of the Korean Geotechnical Society
• /
• v.27 no.9
• /
• pp.87-98
• /
• 2011

In this study, the magnitude and phase variation of dynamic earth pressure acting on a pile in liquefiable soils were analyzed using a series of 1g shaking table tests. In the case of a pile in dry sand, the value of the dynamic earth pressure was the highest near the surface due to the inertia force of the upper load on the pile and it decreased as the depth of the pile got lower. On the other hand, for a pile in liquefiable sand, the magnitude and shape of the dynamic earth pressure were similar to those of the excess pore pressure and was largely affected by the deformation of soils. Furthermore, the inertia force of the upper load and the dynamic earth pressure acted in opposite directions in cases of dry sand and saturated sand where low excess pore pressure had developed. However, after liquefaction, those force components near surface acted unfavorably in the same direction. Finally, the Westergaard’s solution was modified and proposed as a method to evaluate the magnitude of dynamic earth pressure acting on a pile during liquefaction.

• Korean Journal of Construction Engineering and Management
• /
• v.13 no.2
• /
• pp.37-47
• /
• 2012

Engaged number in the construction industry is 45 percentage level against to manufacturing industry. And Induction -factor of Production is much the same to mfg. field, Value added Induction-factor is more higher than manufacturing industry, therefore we research again about workers' inferior working & personal life condition in our society in order to they feel happiness their life with pride for the job construction occupation. So construction companies & government will be contribute to strengthen their phase & to achieve more higher level of construction working culture for elevate competitive power. We have to prepare the basis to turn to the qualitative construction businesses by break away from only the amount of work volume in company with the system of workers' self-conceit on the ground of professional education/training, qualification system, social insurance benefits, working condition improvement, stable job. Our nations does not feel well-being senses, only 25 class level in the 30 countries of OECD. We draw the questions at issue with slough off old customs in order to qualitative improvement for profession & self-contentment of construction workers, and present the useful plan to contribute to international competitiveness with our construction firms in the globalize construction field under Government's & company's policy.

• Journal of the Institute of Electronics Engineers of Korea SD
• /
• v.39 no.5
• /
• pp.8-15
• /
• 2002

We optimally designed the VCO(voltage-controlled oscillator) with spiral inductor using the MOSIS HP 0.5${\mu}{\textrm}{m}$ CMOS process. With the developed SPICE model of spiral inductor, the quality factor of spiral inductor was maximized at the operating frequency by varying the layout parameters, e.g., metal width, number of turns, radius, space of the metal lines. For the operation frequency of 2㎓, the inductance of about 3nH, and the MOSIS HP 0.5 CMOS process with the metal thickness of 0.8${\mu}{\textrm}{m}$, oxide thickness of 3${\mu}{\textrm}{m}$, the optimal width of metal lines is about 20${\mu}{\textrm}{m}$ for the maximum Quality factor. With the optimized spiral inductor, the VCO with LC tuning tank was designed, fabricated and measured. The measurements were peformed on-wafer using the HP8593E spectrum analyzer. The oscillation frequency was about 1.610Hz, the frequency variation of 250MHz(15%) with control voltage of 0V - 2V, and the phase noise of -108.4㏈c(@600KHz) from output spectrum.

• Journal of Bio-Environment Control
• /
• v.11 no.2
• /
• pp.56-60
• /
• 2002

Since the transmittance of solar radiation directly affected by the structural frames of greenhouse can be changed according to the ratio of diffuse to direct radiations, it is necessary to investigate the transmittance of greenhouse at the different weather conditions. We can easily get the data of total solar radiation from the Meteorological Administration, but we have to personally measure the photosynthetic photon flux (PPF). If the relationship between total solar radiation and PPF is established, the PPF can be simply acquired from the relationship. Sol it is required to develop the equation to calculate PPF depending on weather condition. This study was conducted to determine the transmittance of PPF at canopy level in glasshouse and the correlation between total solar radiation and PPF at clear and cloudy days. The variation phase of greenhouse transmittance at clear day was very different from that at cloudy day. It was concluded that the proper transmittance, depending on the weather condition, should be adopted to calculate the accurate total solar radiation and PPF in greenhouse. The transmittance of solar radiation was the same as that of PPF in greenhouse. It was confirmed that the ratio of PPF to total radiation increased as the amount of cloud increased. The correlation between the hourly total solar radiation and PPF was derived.

• Atmosphere
• /
• v.23 no.4
• /
• pp.527-538
• /
• 2013

In this study, climate over Korea based on the Historical scenario induced by HadGEM2-AO is simulated by WRF. For this purpose, a system that can be used be for numerical integration over the Far East Asian area of the center of the Korean Peninsula with 12.5 km-horizontal resolution was set-up at "Haebit", the early portion of KMA Supercomputer Unit-3. Using the system, the downscaling experiments were conducted for the period 1979-2010. The simulated results of HadGEM2-AO and WRF are presented in terms of 2 m-temperature and precipitation during boreal summer and winter of Historical for the period 1981~2005, compared with observation. As for the mean 2 m-temperature, the general patterns of HadGEM2-AO and WRF are similar with observation although WRF showed lower values than observation due to the systematic bias. WRF reproduced a feature of the terrain-following characteristics reasonably well owing to the increased horizontal resolution. Both of the models simulated the observed precipitation pattern for DJF than JJA reasonably, while the rainfall over the Korean Peninsula in JJA is less than observation. HadGEM2-AO in DJF 2 m-temperature and JJA precipitation has warm and dry biases over the Korean Peninsula, respectively. WRF showed cold bias over JJA 2 m-temperature and wet bias over DJF precipitation. The larger bias in WRF was attributed to the addition of HadGEM2-AO's bias to WRF's systematic bias. Spatial correlation analysis revealed that HadGEM2-AO and WRF had above 0.8 correlation coefficients except for JJA precipitation. In the EOF analysis, both models results explained basically same phase changes and variation as observation. Despite the difference in mean and bias fields for both models, the variabilities of the two models were almost similar with observation in many respects, implying that the downscaled results can be effectively used for the study of regional climate around the Korean Peninsula.

• Journal of the Korean Society of Radiology
• /
• v.9 no.5
• /
• pp.307-314
• /
• 2015

This study was conducted in reducing the involuntary motion artifacts because of lungs and heart movements as well as the aliasing artifacts generated during the use of the reduced-FOV EPI technique while performing breast MRI. Performed on a total of 38 obesity female subjects who visited the clinic for pre-examination before surgery within the period from August 1 to November 30, 2014. The 3.0T MRI scanner equipped with a breast scanning coil. Qualitative and quantitative analyses were each used for the evaluation of the acquired images while an Paired T-test and Wilcoxon rank test were performed to check the statistical significance. The variation ratio rose by 15.69% with the additional application of a pre-saturation pulse in the lesion, by 13.72% near the lesion, and 20.63% in the fat and the contrast-to-noise ratio rose by 10.58% in and near the lesion and by 12.03% in the lesion and fat, respectively. there were increases of 22.05% and 21.42% at 0 and 1000 respectively in qulitative evaluation and growth of 16.10% in apparent diffusion coefficient. it showed a statistically significant result(p<0.05) in signal to noise ratio, contrast to noise ratio, diffusion slope coefficient and apparent diffusion coefficient. The involuntary movements artifacts that occur in the phase encoding direction and the aliasing artifacts are considered to be reduced to obtain the best image in the additional use of the pre-saturation pulse as DWI is acquired.

• Applied Chemistry for Engineering
• /
• v.29 no.5
• /
• pp.581-588
• /
• 2018

In this article, electrochemical investigation of the transfer reaction of ionizable cefotiam (CTM), an antibiotic molecule across a polarized water/1,2-dichloroethane (water/1,2-DCE) interface was studied. Ion partition diagram providing the preferred charged form of CTM in either water or 1,2-DCE phase was established via the voltammetric evaluation of the transfer process of differently charged CTM species depending upon the pH variation of aqueous solutions. Thermodynamic information including the formal transfer potential and formal Gibbs transfer energy values in addition to important pharmacokinetics including partition coefficients of ionizable CTM were also evaluated. In particular, the current associated with the transfer of CTM present at pH 3.0 aqueous solution proportionally increased with respect to the CTM concentration which was further used for developing CTM sensitive ion sensor. In order to improve the portability and convenient usage, a single microhole interface fabricated in a supportive polyethylene terephthalate film was used of which hole was filled with a polyvinylchloride-2-nitrophenyloctylether (PVC-NPOE) gel replacing 1,2-DCE, a toxic organic solvent. A dynamic range of $1-10{\mu}M$ CTM was obtained.

• The Journal of the Institute of Internet, Broadcasting and Communication
• /
• v.12 no.4
• /
• pp.7-13
• /
• 2012

The performance of blind equalization algorithm ISCA was compared with MSCA that is used for the minimization of the inter symbol interference which occurs in the time dispersive communication channel for digital transmission. Because of the non-linearities of a magnitude and phase transfer characteristics of a communication channel, the transmitting signal will be received that band limited and time dispersived. Therefore the distortion was compensated by using the self adaptive equalizer at the receiving side, then passing through the detector for the decision of "1" or "0". At this time the Constellation Dependent Constant is played an important role in the adaptive equalizer used on the receiver. In order to calculation of this constant, the ISCA and MSCA was used the second order statistics. The ISCA and MSCA which are possible to compensation of mensioned transfer function simulataneously, are improved the performance of original SCA algorithm and then was compared the performance by computer simulation. For this, the recovered constellation, residual isi and MSE was used, and a result of performance comparison, the ISCA algorithm has better than the MSCA in every performance index. But on the steady state of equalizer, the variation of performance due to the CME terms in the MSCA equalization algorithm was less than the ISCA, so MSCA has better stability.

• Journal of the Institute of Electronics and Information Engineers
• /
• v.53 no.4
• /
• pp.159-166
• /
• 2016

In this paper, an active object tracking system basing on the pan/tilt-embedded stereo camera system is suggested and implemented. In the proposed system, once the face area of a target is detected from the input stereo image by using a YCbCr color model and phase-type correlation scheme and then, using this data as well as the geometric information of the tracking system, the distance and 3D information of the target are effectively extracted in real-time. Basing on these extracted data the pan/tilted-embedded stereo camera system is adaptively controlled and as a result, the proposed system can track the target adaptively under the various circumstance of the target. From some experiments using 480 frames of the test input stereo image, it is analyzed that a standard variation between the measured and computed the estimated target's height and an error ratio between the measured and computed 3D coordinate values of the target is also kept to be very low value of 1.03 and 1.18% on average, respectively. From these good experimental results a possibility of implementing a new real-time intelligent stereo target tracking and surveillance system using the proposed scheme is finally suggested.