• Nuclear Engineering and Technology
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• v.38 no.3
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• pp.231-238
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• 2006

Whole-body exposure to high-dose radiation causes injury involving multiple organs that depends on their sensitivity to radiation. This acute radiation syndrome (ARS) is caused by a brief exposure of a major part of the body to radiation at a relatively high dose rate. ARS is characterized by an initial prodromal stage, a latent symptom-free period, a critical or manifestation phase that usually takes one of four forms (three forms): hematologic, gastrointestinal, or cardiovascular and neurological (neurovascular), depending upon the exposure dose, and a recovery phase or death. One of the most important factors in treating victims exposed to radiation is the estimation of the exposure dose. When high-dose exposure is considered, initial dose estimation must be performed in order to make strategy decisions for treatment as soon as possible. Dose estimation can be based on onset and severity of prodromal symptoms, decline in absolute lymphocyte count post exposure, and chromosomal analysis of peripheral blood lymphocytes. Moreover, dose assessment on the basis of calculation from reconstruction of the radiation event may be required. Experience of a criticality accident occurring in 1999 at Tokai-mura, Japan, showed that ARS led to multiple organ failure (MOF). This article will review ARS and discuss the possible mechanisms of MOF developing from ARS.

• Journal of Biomedical Engineering Research
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• v.30 no.6
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• pp.461-468
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• 2009

Magnetic resonance electrical impedance tomography (MREIT) enables us to perform high-resolution conductivity imaging of an electrically conducting object. Injecting low-frequency current through a pair of surface electrodes, we measure an induced magnetic flux density using an MRI scanner and this requires a sophisticated MR phase imaging method. Applying a conductivity image reconstruction algorithm to measured magnetic flux density data subject to multiple injection currents, we can produce multi-slice cross-sectional conductivity images. When there exists a local region of fat, the well-known chemical shift phenomenon produces misalignments of pixels in MR images. This may result in artifacts in magnetic flux density image and consequently in conductivity image. In this paper, we investigate chemical shift artifact correction in MREIT based on the well-known three-point Dixon technique. The major difference is in the fact that we must focus on the phase image in MREIT. Using three Dixon data sets, we explain how to calculate a magnetic flux density image without chemical shift artifact. We test the correction method through imaging experiments of a cheese phantom and postmortem canine head. Experimental results clearly show that the method effectively eliminates artifacts related with the chemical shift phenomenon in a reconstructed conductivity image.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.8 no.12
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• pp.4552-4567
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• 2014

A (n,t,n) secret sharing scheme is to share a secret among n group members, where each member also plays a role of a dealer,and any t shares can be used to recover the secret. In this paper, we propose a strong (k,t,n) verifiable multi-secret sharing scheme, where any k out of n participants operate as dealers. The scheme realizes both threshold structure and adversary structure simultaneously, and removes a trusted third party. The secret reconstruction phase is performed using an additive homomorphism for decreasing the storage cost. Meanwhile, the scheme achieves the pre-verification property in the sense that any participant doesn't need to reveal any information about real master shares in the verification phase. We compare our proposal with the previous (n,t,n) secret sharing schemes from the perspectives of what kinds of access structures they achieve, what kinds of functionalities they support and whether heavy storage cost for secret share is required. Then it shows that our scheme takes the following advantages: (a) realizing the adversary structure, (b) allowing any k out of n participants to operate as dealers, (c) small sized secret share. Moreover, our proposed scheme is a favorable candidate to be used in many applications, such as secure multi-party computation and privacy preserving data mining, etc.

• Food Science of Animal Resources
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• v.35 no.5
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• pp.692-702
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• 2015

Lactobacillus mucosae is a natural resident of the gastrointestinal tract of humans and animals and a potential probiotic bacterium. To understand the global protein expression profile and metabolic features of L. mucosae LM1 in the early stationary phase, the QExactive^TM Hybrid Quadrupole-Orbitrap Mass Spectrometer was used. Characterization of the intracellular proteome identified 842 proteins, accounting for approximately 35% of the 2,404 protein-coding sequences in the complete genome of L. mucosae LM1. Proteome quantification using QExactive^TM Orbitrap MS detected 19 highly abundant proteins (> 1.0% of the intracellular proteome), including CysK (cysteine synthase, 5.41%) and EF-Tu (elongation factor Tu, 4.91%), which are involved in cell survival against environmental stresses. Metabolic pathway annotation of LM1 proteome using the Kyoto Encyclopedia of Genes and Genomes (KEGG) database showed that half of the proteins expressed are important for basic metabolic and biosynthetic processes, and the other half might be structurally important or involved in basic cellular processes. In addition, glycogen biosynthesis was activated in the early stationary phase, which is important for energy storage and maintenance. The proteogenomic data presented in this study provide a suitable reference to understand the protein expression pattern of lactobacilli in standard conditions

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.9A
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• pp.835-843
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• 2010

Energy spreading transform (EST) based equalization is a very effective technique to remove inter symbol interference (ISI) in frequency selective channel. EST based system uses cyclic prefix (CP) similar to orthogonal frequency division multiplexing (OFDM) system. Since CP is a redundancy, it degrades the data transmission rate. RISIC is an algorithm that removes an inter block interference (IBI) caused by insufficient CP length and reconstructs CP. In this paper, we propose a system that combines the existing EST system with quadrature phase shift keying (QPSK) modulation and RISIC algorithm to enhance the efficiency of the transmission. Also we extend the proposed system to 16 quadrature amplitude modulation (QAM) modulation. The proposed system is shown to performance close to matched filter bound (MFB) even with insufficient CP.

• Investigative Magnetic Resonance Imaging
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• v.7 no.1
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• pp.12-21
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• 2003

Purpose : In order to overcome limitations in the existing conventional spectrometer, a new spectrometer with advanced functionalities is designed and implemented. Materials and Methods : We designed a spectrometer using the TMS320C6701 DSP capable of 1 giga floating point operations per second (GFLOPS). The spectrometer can generate continuously varying complicate gradient waveforms by real-time calculation, and select image plane interactively. The designed spectrometer is composed of two parts: one is DSP-based digital control part, and the other is analog part generating gradient and RF waveforms, and performing demodulation of the received RF signal. Each recover board can measure 4 channel FID signals simultaneously for parallel imaging, and provides fast reconstruction using the high speed DSP. Results : The developed spectrometer was installed on a 1.5 Tesla whole body MRI system, and performance was tested by various methods. The accurate phase control required in digital modulation and demodulation was tested, and multi-channel acquisition was examined with phase-array coil imaging. Superior image quality is obtained by the developed spectrometer compared to existing commercial spectrometer especially in the fast spin echo images. Conclusion : Interactive control of the selection planes and real-time generation of gradient waveforms are important functions required for advanced imaging such as spiral scan cardiac imaging. Multi-channel acquisition is also highly demanding for parallel imaging. In this paper a spectrometer having such functionalities is designed and developed using the TMS320C6701 DSP having 1 GFLOPS computational power. Accurate phase control was achieved by the digital modulation and demodulation techniques. Superior image qualities are obtained by the developed spectrometer for various imaging techniques including FSE, GE, and angiography compared to those obtained by the existing commercial spectrometer.

• Journal of the Korean Solar Energy Society
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• v.25 no.1
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• pp.87-96
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• 2005

본 논문은 압력차로 인한 유체의 유동장에서 서스펜션의 입자 밀도를 분포 규명하기 위해 적용할 수 있는 Electric Impedance Tomography (EIT)의 새로운 기법에 대한 효율성을 다루고 있다. Regularized Newton-Raphson iterative method를 근간으로 inverse problem의 해를 구하는데, 이는 곧 목적 함수(object function)를 몇 가지의 제한조건(constraints) 하에서 최소화시키는 과정이라 할 수 있다. 한편, 관련 forward problem은 유한요소법(FEM)을 이용하여 해결하며, 기존의 연구와는 달리 선형 형상 함수(linear shape function)를 이용하여 전도도가 연속적인 물성치로 유동장에 분포되어 있는 것으로 가정하였다. 여러 경우의 test run에 대한 결과는 본 논문에서 적용한 방법론의 타당성을 보여 주고 있다. 태양에너지의 추출을 위해 직접촉식 열교환기가 종종 이용되고 있는데, 본 연구는 열교환기 내부의 분산 유체에 대한 해석에 일조를 할 수 있을 것으로 기대된다.

• Journal of Korea Multimedia Society
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• v.19 no.2
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• pp.224-232
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• 2016

The methodology to visualize the shape of blood vessel and its blood flow have been attracting as a very interesting problem to forecast and examinate a disease in thrombus precursor protein. May previous visualization researches have been appeared for designing the blood vessel and also modeling the blood flow using a doppler imaging technique which is one of nondestructive testing techniques. General visualization methods are to depict the blood flow obtained from doppler effects with fragmentary stream lines and also visualize the blood flow model using volume rendering. However, these visualizeation techniques have the disadvantage which a set of small line segments does not give the overall observation of blood flows. Therefore, we propose a visualization system which reconstruct the continuity of the blood flow obtained from doppler effects and also visualize the blood flow with the vector field of blood particles. This system will use doppler phase difference from medical equipments such as OCT with low penetration and reconstruct the blood flow by the curvature estimation from vector field of each blood particle.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.24 no.1
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• pp.93-101
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• 2000

The characteristics of spray nozzle have been quantified with the measurement of fluorescence and Mie scattering images. To correct the attenuation of the incident light sheet, a sequential double-pass light sheet system and the geometrical averaging of two images was implemented. Quantitative mass flux distribution of spray was obtained from fluorescence image. 3-D image is reconstructed using 2-D radial images. Sauter mean diameter (SMD) distribution was determined using the ratio of fluorescence signal intensity and Mie scattering signal intensity and the values were quantified with PDP A data. The measurement of mass flux and SMD using planar imaging technique agee with PDP A data fairly well in the low density region. However, in dense region， there are significant errors caused by secondary scattering. It was found that the planar imaging technique provides many advantages over the point measurement technique, such as PDP A, and can be implemented for quantitative measurement, especially in low density region.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2003.10a
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• pp.221-228
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• 2003

This paper presents a novel method that can identify the individual's haplotype from the given genotypes. Because of the limitation of the conventional single-locus analysis, haplotypes have gained increasing attention in the mapping of complex-disease genes. Conventionally there are two approaches which resolve the individual's haplotypes. One is the molecular haplotypings which have many potential limitations in cost and convenience. The other is the in-silico haplotypings which phase the haplotypes from the diploid genotyped populations, and are cost effective and high-throughput method. In-silico haplotyping is divided into two sub-categories - statistical and computational method. The former computes the frequencies of the common haplotypes, and then resolves the individual's haplotypes. The latter directly resolves the individual's haplotypes using the perfect phylogeny model first proposed by Dan Gusfield [7]. Our method combines two approaches in order to increase the accuracy and the running time. The individuals' haplotypes are resolved by considering the MLE (Maximum Likelihood Estimation) in the process of computing the frequencies of the common haplotypes.