• Title/Summary/Keyword: Phase II design

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Numerical and Experimental Thermal Validation on Pogo-pin based Wire Cutting Mechanism for CubeSat Applications (큐브위성용 포고핀 기반 열선절단 분리장치의 열적 거동 분석 및 검증)

  • Min-Young Son;Bong-Geon Chae;Hyun-Ung Oh
    • Journal of Aerospace System Engineering
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    • v.17 no.2
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    • pp.94-102
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    • 2023
  • A nylon wire holding and release mechanism (HRM) has been widely used for deployable applications of CubeSat owing to its simplicity and low cost. In general, structural safety of solar panel with an HRM has been designed by performing structural analysis under a launch environment. However, previous studies have not performed thermal analysis for HRM in an on-orbit environment. In this study, Launch and Early Orbit Phase (LEOP) thermal analysis was performed to evaluate thermal stability of the mechanism in the orbital thermal environment of the pogo pin-based HRM applied to CubeSat. In addition, the effectiveness of the thermal design and performance of the pogo pin-based HRM were verified through a thermal vacuum test.

Design and Development of 200 W TRM on-board for NEXTSat-2 X-band SAR (차세대소형위성2호의 X대역 합성 개구 레이더 탑재를 위한 200 W급 송·수신 모듈의 설계 및 개발)

  • Jeeheung Kim;Hyuntae Choi;Jungsu Lee;Tae Seong Jang
    • Journal of Advanced Navigation Technology
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    • v.26 no.6
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    • pp.487-495
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    • 2022
  • This paper describes the design and development of a high-power transmit receive module(TRM) for mounting on X-band synthetic aperture radar(SAR) of the NEXTSat-2. The TRM generates a high-power pulse signal with a bandwidth of 100 MHz in the target frequency range of X-band and amplifies a low-noise on the received signal. Tx. path of the TRM has output signal level of more than 200 watts (53.01 dB), pulse droop of 0.35 dB, signal strength change of 0.04 dB during transmission signal output, and phase change of 1.7 ˚. Rx. path has noise figure of 3.99 dB and gain of 37.38 ~ 37.46 dB. It was confirmed the TRM satisfies all requirements. The TRM mounted on the NEXTSat-2 flight model(FM) which will be launched using the KSLV-II (Nuri).

The Effect of Stress on SCC of Heat Exchanger Tube for LNG Vessel (LNG선박용 열교환기 세관의 SCC에 미치는 응력의 영향)

  • Jeong Hae Kyoo;Lim Uh Joh
    • Journal of the Korean Institute of Gas
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    • v.7 no.2 s.19
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    • pp.22-32
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    • 2003
  • Al-brass material is generally used at the state of plastic deformation, for example; bending, extension of bell mouth at shell and tube type heat exchanger. And SCC(stress corrosion cracking) of Al-brass material will be affected by residual stress as plastic deformation. SCC results from synergism between mechanical factor and corrosion environment. Mechanical factor is stress that directly relates with stress intensity factor at the crack tip. This paper was studied on the effect of stress on SCC of Al-brass tube under in $3.5\%$ NaCl. + $0.1\%\;NH_4OH$ solution by constant displacement tester. Increasing of acidified water flow into sea and speeds up corrosion rate of Al-brass which is used as a tube material of vessel heat exchanger by polluted coast seawater. The experimental results are as follow The latent time of SCC occurrence gets longer as the initial stress intensity factor($K_{Ii}$) gets lower The main crack was propagated as the initial stress intensity factor($K_{Ii}$) gets higher, and secondary cracks occurred by electro-chemical factor a(ter stage of released stress. Dezincification phase showed around the crack, and the range of dezincification gets wider as the initial stress intensity factor($K_{Ii}$) gets higher.

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Blend of essential oils can reduce diarrheal disorders and improve liver antioxidant status in weaning piglets

  • Maiara Ananda, Grando;Vanessa, Costa;Jansller Luiz, Genova;Paulo Evaristo, Rupolo;Liliana Bury, de Azevedo;Leandro Batista, Costa;Silvana Teixeira, Carvalho;Thiago Pereira, Ribeiro;Daniel Pigatto, Monteiro;Paulo Levi, de Oliveira Carvalho
    • Animal Bioscience
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    • v.36 no.1
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    • pp.119-131
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    • 2023
  • Objective: This study was to assess the effects of different doses of an essential oil blend (EOB) on growth performance, diarrhea occurrence (DO), hematological and blood biochemical profile, intestinal morphometry, morphology and microbiology, relative weight and length of organs, digestive content pH, and liver antioxidant status in weaning piglets. Methods: A total of 135 barrows (7.09±0.29 kg body weight) were allotted randomly in a randomized complete block design based on body weight with nine replications and three animals per pen. Dietary treatments were a negative control (NC): basal diet; positive control (PC): NC plus 125 mg performance-enhancing antibiotic (enramycin 8%)/kg diet; NC plus 100 mg EOB/kg diet (EO100); NC plus 200 mg EOB/kg diet (EO200); and NC plus 400 mg EOB/kg diet (EO400). Diarrhea occurrence was monitored daily, and performance at the end of each phase. Results: Gain to feed ratio was greater (p<0.05) in starter II pigs fed EO400 and EO200 than in those fed EO100. Pigs fed EO400 had lower (p<0.05) DO than those fed NC and EO100 in the total period. Pre-starter II pigs fed NC had (p<0.05) lower serum total protein and plasma protein than pigs fed PC. Pigs fed EO100 showed smaller (p<0.05) mean corpuscular volume (MCV) than pigs fed EO400. Starter II pigs fed EO400 had (p<0.05) greater MCV and lower mean corpuscular hemoglobin and erythrocytes than those fed EO100. There was a greater concentration (p<0.05) of band cells for PC, similar to EO400 and EO200. Performance-enhancing antibiotic and EOB to diets increased (p<0.05) liver superoxide dismutase activity. Conclusion: Adding 200 and 400 mg EOB/kg diet decreased DO and was advantageous to hematological and blood biochemical profile and liver antioxidant status without being detrimental to growth performance and gastrointestinal health in nursery pigs.

Optimal design of a nonparametric Shewhart-Lepage control chart (비모수적 Shewhart-Lepage 관리도의 최적 설계)

  • Lee, Sungmin;Lee, Jaeheon
    • Journal of the Korean Data and Information Science Society
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    • v.28 no.2
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    • pp.339-348
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    • 2017
  • One of the major issues of statistical process control for variables data is monitoring both the mean and the standard deviation. The traditional approach to monitor these parameters is to simultaneously use two seperate control charts. However there have been some works on developing a single chart using a single plotting statistic for joint monitoring, and it is claimed that they are simpler and may be more appealing than the traditonal one from a practical point of view. When using these control charts for variables data, estimating in-control parameters and checking the normality assumption are the very important step. Nonparametric Shewhart-Lepage chart, proposed by Mukherjee and Chakraborti (2012), is an attractive option, because this chart uses only a single control statistic, and does not require the in-control parameters and the underlying continuous distribution. In this paper, we introduce the Shewhart-Lepage chart, and propose the design procedure to find the optimal diagnosis limits when the location and the scale parameters change simultaneously. We also compare the efficiency of the proposed method with that of Mukherjee and Chakraborti (2012).

Workload Measurement of Home Health Care Nurses상 Services using Relative Value Units (가정간호행위 업무량의 상대적 가치 측정에 관한 연구)

  • 이태화;박정숙;김인숙
    • Journal of Korean Academy of Nursing
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    • v.30 no.6
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    • pp.1543-1555
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    • 2000
  • Home health care is moving into a set of new realities. An era of competition and cost containment has arrived. Before nurses are able to contain costs or describe the relationship between nursing activities, cost must be accurately measured based on the nurse's workload. Nurses in home health care usually desire to measure expenses for one of three reasons : reimbursement, management, or research. The purpose of the study was to investigate the work input by Registered Nurse in each of the home health care activities by relative value units and identify the factors affecting the nurses' total work input in health care services. To measure the work input by nurses, work was defined by four dimensions: time, physical effort, mental effort, and stress. This study used a descriptive-correlational design. Data collection consisted of two phases. In phase I, data on home health activities performed by nurses were collected. In phase II, data on nurses' time, physical effort, mental effort, and stress in each of home health care activities discovered phase I were collected. In this method, the respondent was asked to rate a service in relation to a reference service using a ratio scale. The sample included 39 home health care nurses. The results of the study indicated that home health care activities performed by the nurses were in 10 categories and 69 items. Measuring the relative work inputs in each of home health care activities, and foley catheterization was selected as the reference to service. In terms of time and physical effort dimensions, full bath service was rated as the most strenuous among 69 activities by the respondents, and intramuscular injection was rated as least. It was found that emergency treatment required the highest mental effort and the highest stress, while blood sugar tests required the lowest mental effort. Approximately 91.3% of the variance in total work input was accounted for by the linear combination of time, physical effort, mental effort judgement, and stress. Examining the regression coefficients of those variables, physical effort, time, and stress were found as the predictors which were significantly associated with the total work of nurses in home health care. Professional nursing's next step in the conundrum of economic volatility is to develop a tool to reflect the interaction of functional deficiency and direct professional nursing care. And this will be a more accurate predictor of nursing resource use and ultimately a great forcaeter cost.

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Effects of Diet Complexity and Fermented Soy Protein on Growth Performance and Apparent Ileal Amino Acid Digestibility in Weanling Pigs

  • Ao, X.;Kim, H.J.;Meng, Q.W.;Yan, L.;Cho, J.H.;Kim, I.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.11
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    • pp.1496-1502
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    • 2010
  • Two experiments were conducted to evaluate the effects of diet complexity and fermented soy protein on growth performance and amino acid digestibility. In Exp. 1, a total of 120 crossbred weanling pigs ($5.68{\pm}0.80\;kg$ BW) were randomly allocated into 4 treatments. Each treatment had 6 replicate pens comprising 5 pigs in each replicate. Experimental diets consisted of simple (soybean meal as protein source) and complex (soybean meal, rice protein concentrate, potato protein concentrate and fish meal as protein sources) diets; each diet contained 0 or 5% fermented soy protein (FSP), respectively. Dietary treatments included: i) simple diet; ii) simple diet with 5% FSP; iii) complex diet; iv) complex diet with 5% FSP. Pigs were provided each experimental diet for 20 d (phase 1) and then fed the same common diet for 10 d (phase 2). During days 0-10, pigs fed FSP diets had greater ADG than those fed non-FSP diets (p<0.05). G/F in FSP treatments was significantly higher than that in non-FSP treatments (p<0.05) from days 0 to 10. Throughout the overall period, G/F was greater in FSP treatments compared with non-FSP treatments (p<0.05). On d 10, N digestibility was higher in pigs fed FSP diets than in those fed non-FSP diets (p<0.05). Diet complexity did not affect growth performance and nutrient digestibility (p>0.05) in this experiment. In Exp 2, 12 ileal-cannulated, weanling barrows were housed in individual metabolism crates and randomly assigned to 1 of 4 treatments (same as Exp. 1) by using a $4{\times}4$ Latin square design. Among the essential amino acids, apparent ileal digestibility (AID) of Met and Val were increased in pigs fed FSP diets compared with those fed non-FSP diets (p<0.05). AID of Met, Phe and total essential amino acids were higher in pigs fed complex diets than in those fed simple diets (p<0.05). Among the non-essential amino acids, AID of Ala in FSP treatments was greater than that in non-FSP treatments (p<0.05). In addition, Asp, Cys, Glu, Pro, Ser and total non-essential amino acid digestibilities in pigs fed complex diets were higher compared with those fed simple diets (p<0.05). Interaction was observed in AID of Met, Asp and Pro. In conclusion, these results indicated that feeding of 5% FSP to nursery pigs improved feed efficiency and AID of amino acids, and diet complexity did not maximize the growth performance of pigs in the subsequent phase.

Redesign Application Architecture for Advanced Volcanic Disaster Response System (화산재해대응시스템 고도화를 위한 응용아키텍처 재설계)

  • Youn, Junhee;Kim, Tae-Hoon;Kim, Dusik
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.3
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    • pp.90-95
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    • 2018
  • The Korean Peninsula is no longer safe from volcanic disasters. Therefore, the Korean government has been developing a spatial information-based system implementation technology since 2014. VDRS (Volcanic Disaster Response System), which is the result of the technology, was implemented in 2016 as Phase I. Since then, phase II implementation technology has been developed for an advanced system reflecting the user's requirements. To advance the system, redesign architecture is essential. This paper examined the redesign application architecture for an advanced VDRS. First, existing application architecture, which was implemented in phase I, was analyzed. Second, the user's requirements for advanced VDRS were analyzed. The analyzed user's requirements were categorized as a transforming service oriented to a business-oriented architecture, improving accuracy, and expanding the spatial range and target disaster. Third, application architecture was redesigned based on gap analysis between the existing architecture and user's requirements. The results of the proposed redesign architecture are presented as the application system structure and description of the application function based on owner's point of view in the enterprise architecture. The results of this paper can be used to derive the application module design and provide a detailed description of the application module based on the designer's point of view. Further research focused on structuring the HW/SW architecture will be required for system implementation.

Dosimetric Analysis of a Phase I Study of PSMA-Targeting Radiopharmaceutical Therapy With [177Lu]Ludotadipep in Patients With Metastatic Castration-Resistant Prostate Cancer

  • Seunggyun Ha;Joo Hyun O;Chansoo Park;Sun Ha Boo;Ie Ryung Yoo;Hyong Woo Moon;Dae Yoon Chi;Ji Youl Lee
    • Korean Journal of Radiology
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    • v.25 no.2
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    • pp.179-188
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    • 2024
  • Objective: 177Lutetium [Lu] Ludotadipep is a novel prostate-specific membrane antigen targeting therapeutic agent with an albumin motif added to increase uptake in the tumors. We assessed the biodistribution and dosimetry of [177Lu]Ludotadipep in patients with metastatic castration-resistant prostate cancer (mCRPC). Materials and Methods: Data from 25 patients (median age, 73 years; range, 60-90) with mCRPC from a phase I study with activity escalation design of single administration of [177Lu]Ludotadipep (1.85, 2.78, 3.70, 4.63, and 5.55 GBq) were assessed. Activity in the salivary glands, lungs, liver, kidneys, and spleen was estimated from whole-body scan and abdominal SPECT/CT images acquired at 2, 24, 48, 72, and 168 h after administration of [177Lu]Ludotadipep. Red marrow activity was calculated from blood samples obtained at 3, 10, 30, 60, and 180 min, and at 24, 48, and 72 h after administration. Organand tumor-based absorbed dose calculations were performed using IDAC-Dose 2.1. Results: Absorbed dose coefficient (mean ± standard deviation) of normal organs was 1.17 ± 0.81 Gy/GBq for salivary glands, 0.05 ± 0.02 Gy/GBq for lungs, 0.14 ± 0.06 Gy/GBq for liver, 0.77 ± 0.28 Gy/GBq for kidneys, 0.12 ± 0.06 Gy/GBq for spleen, and 0.07 ± 0.02 Gy/GBq for red marrow. The absorbed dose coefficient of the tumors was 10.43 ± 7.77 Gy/GBq. Conclusion: [177Lu]Ludotadipep is expected to be safe at the dose of 3.7 GBq times 6 cycles planned for a phase II clinical trial with kidneys and bone marrow being the critical organs, and shows a high tumor absorbed dose.

Effect of Dietary Grape Pomace Fermented by Saccharomyces boulardii on the Growth Performance, Nutrient Digestibility and Meat Quality in Finishing Pigs

  • Yan, L.;Kim, I.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.12
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    • pp.1763-1770
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    • 2011
  • Fifty-six [(Duroc${\times}$Yorkshire)${\times}$Landrace] pigs with an average initial BW of 19.3${\pm}$0.17 kg were used in this 15-wk growth experiment to investigate the effects of grape pomace fermented by Saccharomyces boulardii on pig growth performance, nutrient digestibility and quality attributes of pork. Pigs were allotted to 2 dietary treatments (7 replications) based on their initial BW in a randomized complete block design. The experimental treatments were: i) control (CON; basal diet), ii) FGPP (CON+30 g/kg fermented grape pomace product). Dietary FGPP improved (p<0.05) average daily gain (ADG), coefficient apparent total tract digestibility (CATTD) of dry matter (DM) and nitrogen (N) during 35-70 d of the experiment. Similarly, pigs fed the FGPP supplemented diet had a higher N digestibility (p<0.05) in the finisher phase (day 71-105). Dietary FGPP increased (p<0.05) the marbling score, the redness ($a^*$) and yellowness ($b^*$) values, as well as the anti-oxidative ability (lower TBARS). The inclusion of FGPP reduced palmitic acid (C:16:0), stearic acid (C:18:0), arachidic acid (C:20:0) and SFA levels (p<0.05) in subcutaneous fat. An increased (p<0.05) linoleic acid (C18:2n6), total PUFA and PUFA/SFA ratio were observed in the FGPP group. Dietary FGPP supplementation decreased the arachidic acid (C:20:0) level in longissimus muscle (LM). In conclusion, dietary inclusion of FGPP at the level of 30 g/kg improved the growth performance, nutrients digestibility and altered the fatty acid pattern in the subcutaneous fat as well as some attributes of pork meat.