• Title/Summary/Keyword: Phase II design

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Studies for Reliability-corrected Cost Estimation Methodology of Launch Vehicle Development (신뢰성 보정된 발사체 개발비용 추정방안 연구)

  • Kim, Hong-Rae;Yoo, Dong-Seo;Chang, Young-Keun
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.40 no.4
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    • pp.364-374
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    • 2012
  • The purpose of this study is to perform the reliability-corrected development cost estimation of the launch vehicle at the conceptual design phase. In order to estimate the launch vehicle development cost, the estimation method based on the independent variable such as the rocket performance and dry mass has been mainly implemented up to now. This approach has made the approximate cost estimation possible, however, the cost variation according to the reliability requirement could not be reflected. In this paper, the cost estimation methodology that introduces the reliability factor in addition to the performance and mass in the TRANSCOST model is presented in order to improve the limitation of current cost estimation method. The development cost of KSLV(Korea Space Launch Vehicle)-II is estimated on the basis of this newly implemented concept with reliability as an added parameter.

Liquid Oxygen Supercooling System in the 75 tonf-class Liquid Engine Combustion Test Facility (75톤급 액체엔진 연소시험설비의 액체산소 과냉각 시스템)

  • Seo, Daeban;Yoo, Byoungil;Lee, Jungho;Cho, Namkyung;Kim, Seunghan;Han, Yeoungmin
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2017.05a
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    • pp.1080-1083
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    • 2017
  • In the design of KSLV-II, there is a scenario in which supercooled liquid oxygen is supplied to prevent a geysering phenomenon in the oxidizer pipe and a cavitation phenomenon at the pump inlet. To verify this condition in the engine development test phase, a system that supplies supercooled liquid oxygen to the engine was applied in the engine combustion test facility. In this system, supercooling methods using a vacuum ejector and using helium injection to the tank were appied. Both tests were carried out for about 17 minutes. Supercooling results of about 3.3K for the ejector test and about 2.2K for the helium injection test were obtained at the 50% level of the tank.

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Effects of Fat Sources on Growth Performance, Nutrient Digestibility, Serum Traits and Intestinal Morphology in Weaning Pigs

  • Jung, H.J.;Kim, Y.Y.;Han, In K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.16 no.7
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    • pp.1035-1040
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    • 2003
  • This experiment was conducted to investigate the effects of fat sources on growth performance, nutrient digestibility, serum traits and intestinal morphology in weaning pigs. A total of 128 weaning pigs (Landrace${\times}$Large White${\times}$Duroc, $21{\pm}2$ days of age, $5.82{\pm}0.13kg$ of average initial body weight) were allotted in a randomized complete block (RCB) design with four treatments: 1) corn oil, 2) soybean oil, 3) tallow and 4) fish oil. Each treatment had 8 replicates with 4 pigs per pen. During phase I period (d 0 to 14), pigs fed corn oil or soybean oil diet tended to show higher ADG and FCR than any other treatments although there was no significant difference. During phase II period (d 15 to 28), pigs fed corn oil diet showed better ADG and ADFI than pigs fed soybean oil, tallow or fish oil. For overall period, growth performance of weaning pigs was improved (p<0.05) when pigs were fed soybean oil or corn oil. Apparent digestibility of energy and fat was improved when pigs were fed corn oil diet (p<0.05). Supplementation of corn oil resulted in higher serum triglyceride concentration than the other treatments (p<0.05). However, there was a lower cholesterol concentration when corn oil was provided compared to tallow or fish oil. Pigs fed corn oil tended to have increased villus height compared with soybean oil, tallow or fish oil treatment (p<0.05). This experiment suggested that vegetable oils such as corn oil or soybean oil, were much better fat source for improving growth performance of weaning pigs.

Kinematic analysis of rowing exercise using a motor-assisted rowing machine for rowers with spinal cord injury: a case report

  • Jeong, Ju Ri;Lee, Bum Suk;Park, Dae-Sung
    • Physical Therapy Rehabilitation Science
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    • v.3 no.1
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    • pp.69-75
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    • 2014
  • Objective: We developed a Motor-Assisted Rowing Machine (MARM) for Spinal Cord Injury (SCI), by modification of the Concept II rowing machine, so that the seats could be operated automatically in a backward and forward direction by a motor. Design: Case report. Methods: Motor rowing consisted of a chair with inclination control, a motor system, control button, monitor, program, leg supporter, safety belt, and seat. The patients were 2 men rowing athletes with SCI, classified as American Spinal Injury Association class B, participated in the study. Level of thoracic injury ranged from T8 to T10. The subjects rowed at a self-selected stroke rate with 50 watts. Two different rowing methods (static rowing without movement of the seat, dynamic rowing using MARM) were assigned to each participant during 10 minutes; 34 reflective markers were attached to their full bodies. Kinematic data were collected using the Vicon motion analysis system. Based on the full body model provided as a default by the equipment. In the rowing exercise, the rowing motions were divided into Drive Phase and Recovery Phase. Results: The two rowing methods differ in handle range, seat range, handle and seat ratio, handle velocity, and seat velocity during static and dynamic rowing. The rowing exercise using a rowing machine developed MARM increased tendency to the range of motion in the dynamic method compared to the static method. Conclusions: The newly developed MARM could be a useful whole body exercise for people with SCI.

Exploring Critical Risk Factors of Office Building Projects

  • NGUYEN, Phong Thanh;PHAM, Cuong Phu;PHAN, Phuong Thanh;VU, Ngoc Bich;DUONG, My Tien Ha;NGUYEN, Quyen Le Hoang Thuy To
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.2
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    • pp.309-315
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    • 2021
  • Risks and uncertainty are unavoidable problems in management of projects. Therefore, project managers should not only prevent risks, but also have to respond and manage them. Risk management has become a critical interest subject in the construction industry for both practitioners and researchers. This paper presents critical risk factors of office building projects in the construction phase in Ho Chi Minh City, Vietnam. Data was collected through a questionnaire survey based on the likelihood and consequence level of risk factors. These factors fell into five groups: (i) financial risk factors; (ii) management risk factors; (iii) schedule risk factors; (iv) construction risk factors; and (v) environment risk factors. The research results showed that critical factors affecting office building projects are natural (i.e., prolonged rain, storms, climate effects) and human-made issues (i.e., soil instability, safety behaviors, owner's design change) and the schedule-related risk factors contributed to the most significant risks for office buildings projects in the construction phase in Ho Chi Minh City. They give construction management and project management practitioners a new perspective on risks and risk management of office buildings projects in Ho Chi Minh City and are proactive in the awareness, response, and management of risk factors comprehensively.

The KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD): A Korean Chronic Kidney Disease Cohort

  • Oh, Kook-Hwan;Park, Sue K.;Kim, Jayoun;Ahn, Curie
    • Journal of Preventive Medicine and Public Health
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    • v.55 no.4
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    • pp.313-320
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    • 2022
  • The KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD) was launched in 2011 with the support of the Korea Disease Control and Prevention Agency. The study was designed with the aim of exploring the various clinical features and characteristics of chronic kidney disease (CKD) in Koreans, and elucidating the risk factors for CKD progression and adverse outcomes of CKD. For the cohort study, nephrologists at 9 tertiary university-affiliated hospitals participated in patient recruitment and follow-up. Biostatisticians and epidemiologists also participated in the basic design and structuring of the study. From 2011 until 2016, the KNOW-CKD Phase I recruited 2238 adult patients with CKD from stages G1 to G5, who were not receiving renal replacement therapy. The KNOW-CKD Phase II recruitment was started in 2019, with an enrollment target of 1500 subjects, focused on diabetic nephropathy and hypertensive kidney diseases in patients with reduced kidney function who are presumed to be at a higher risk of adverse outcomes. As of 2021, the KNOW-CKD investigators have published articles in the fields of socioeconomics, quality of life, nutrition, physical activity, renal progression, cardiovascular disease and outcomes, anemia, mineral bone disease, serum and urine biomarkers, and international and inter-ethnic comparisons. The KNOW-CKD researchers will elaborate a prediction model for various outcomes of CKD such as the development of end-stage kidney disease, major adverse cardiovascular events, and death.

Effect of $\beta$-glucan Extracted from Youngji Mushroom on the Growth Performance of Weaning Pigs (영지버섯에서 추출한 $\beta$-glucan 이 자돈의 생산능력에 미치는 영향)

  • Kim, Jong-Duk;Shim, Keum-Seob;Choi, Nag-Jin;Kim, Ji-Hoon;Kim, Yong-Hyun;Kwon, Hyun-Jung;Kim, Sun-Ki;Han, Man-Deuk
    • Korean Journal of Organic Agriculture
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    • v.18 no.3
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    • pp.401-418
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    • 2010
  • This experiment was selected a $\beta$-glucan producing mushroom strain and developed industrial media, and used to $\beta$-glucan as an alternative for antibiotics in weaned pigs. Yields of mycelial biomass and extracellular $\beta$-glucan from Youngji (Ganoderma lucidum) mushroom was 8.52g/L and 4.49g/L respectively. Also, we prepared optimum formula for mushroom cultivations. A total of 144 pigs ($8.6{\pm}0.9$ kg average body weight, weaned $20{\pm}3$ days of age) were allotted to 4 different treatment groups and replicated 4 times with 8 pigs per replicate in randomized complete block design. Treatments were T1) NC (negative control, basal diet), T2) PC (positive control, basal diet+0.255% antibiotics), T3) NC+0.2% $\beta$-glucan and T4) PC+0.2% $\beta$-glucan. The T2 and T4 treatments were significantly higher in feed efficiency by antibiotics group (p<0.05), however, there was no significant differences in terms of average daily gain (ADG) and average daily feed intake (ADFI) during phase I (0~14 days). In phase II (15~28 days), Pigs fed with antibiotics and $\beta$-glucan (T4) had greater ADG than other treatments (p<0.05), while no differences were observed in ADFI and feed efficiency. During the whole experiment period, the ADG of T4 treatment was higher than other treatments. Pigs fed with $\beta$-glucan (T3 and T4) had greater diarrhea score and moisture content than other treatments (p<0.05). Pigs fed with $\beta$-glucan (T3 and T4) had greater moisture content than other treatments (p<0.05). However, there was no significant differences in diarrhea score and mortality of weaned pigs. There was marginal reductions in feed cost measured feed cost per weight gain used in antibiotics and $\beta$-glucan added diet during phase I. In the second phase, the treatment supplemented with antibiotics had a significantly lower feed cost per weight gain compared to the other treatments. The results from these experiments suggests that $\beta$-glucan is likely able to improve the growth performance, and reduce feed cost although they do not have similar effects like antibiotics in weaning pigs.

Development of automatic die bonder system for semiconductor parts assembly (반도체 소자용 자동 die bonding system의 개발)

  • 변증남;오상록;서일홍;유범재;안태영;김재옥
    • 제어로봇시스템학회:학술대회논문집
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    • 1988.10a
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    • pp.353-359
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    • 1988
  • In this paper, the design and implementation of a multi-processor based die bonder machine for the semiconductor will be described. This is a final research results carried out for two years from June, 1986 to July, 1988. The mechanical system consists of three subsystems such as bonding head module, wafer feeding module, and lead frame feeding module. The overall control system consists of the following three subsystems each of which employs a 16 bit microprocessor MC 68000 : (i) supervisory control system, (ii) visual recognition / inspection system and (iii) the display system. Specifically, the supervisory control system supervises the whole sequence of die bonder machine, performs a self-diagnostics while it controls the bonding head module according to the prespecified bonding cycle. The vision system recognizes the die to inspect the die quality and deviation / orientation of a die with respect to a reference position, while it controls the wafer feeding module. Finally, the display system performs a character display, image display ans various error messages to communicate with operator. Lead frame feeding module is controlled by this subsystem. It is reported that the proposed control system were applied to an engineering sample and tested in real-time, and the results are sucessful as an engineering sample phase.

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Experimental Study of Boundary Layer Transition on an Airfoil Induced by Periodically Passing Wake (I) -A Time-Averaged Characteristic- (주기적 후류 내의 익형 위 천이경계층에 관한 실험적 연구(I) -시간평균된 유동 특성-)

  • Park, Tae-Chun;Jeon, U-Pyeong;Gang, Sin-Hyeong
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.25 no.6
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    • pp.776-785
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    • 2001
  • Hot-wire measurements are performed in boundary layers developing on a NACA0012 airfoil over which wakes pass periodically. The Reynolds number based on chord length of the airfoil is 2$\times$10(sup)5 and the wakes are generated by circular cylinders rotating clockwise and counterclockwise around the airfoil. This paper and its companion Part II describe the phenomena of wake-induced transition of the boundary layers on the airfoil using measured data; phase-and time-averaged streamwise mean velocities, turbulent fluctuations, integral parameters and wall skin frictions. This paper describes the background and facility together with results of time-averaged quantities. Due to the passing wake with mean velocity defects and high turbulence intensities, the laminar boundary layer is periodically disturbed at the upstream station and becomes steady-state transitional boundary layer at the downstream station. The velocity defect in the passing wake changes the local pressure at the leading of the airfoil, significantly affects the time-mean pressure distribution on the airfoil and eventually, has influence on the transition process of the boundary layer.

Unusual Intronic Variant in GSTP1 in Head and Neck Cancer in Pakistan

  • Masood, Nosheen;Malik, Faraz Arshad;Kayani, Mahmood Akhtar
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.4
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    • pp.1683-1686
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    • 2012
  • In the present case control study mRNA expression of the GSTP1 gene, encoding a phase II enzyme that detoxifies via glutathione conjugation, was investigated using semiquantitative PCR followed by SSCP for 49 confirmed head and neck (HN) cancer and 49 control samples. It was found that GSTP1 was upregulated in significantly higher number of cancers (OR 4.2, 95% CI 1.2-15.3). Grade wise correlation was also observed with more up regulation in patients with more advanced grades of HN carcinomas. We also found that 5 patients showed variation in mRNA with a larger product size than expected. Sequencing revealed insertion of an intronic segment between the $6^{th}$ and $7^{th}$ exon of the GSTP1 gene. Germline screening was performed showing mobility shifts which suggested mutation at the DNA level resulting in intronic portion retention. This study is of prime importance for drug design and treatment selection to overcome increased resistance of HN cancers to drugs due to alteration in the GSTP1 gene.