• 대한방사선기술학회지:방사선기술과학
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• 제29권4호
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• pp.241-247
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• 2006

최근 유방 영상 검사는 의료영상저장전송시스템(Picture Archiving and Communication System, PACS)의 도입과 특수의료장비에 관한 정도관리 실시로 인해 Computed Radiography(CR)과 Digital Radiography(DR)에 관한 관심도와 이용도가 증가하고 있는 추세이다. 본 연구는 유방영상검사에 이용되고 있는 각 시스템별 검출기의 영상 화질을 정도관리 시 사용되는 ACR 팬텀을 이용하여 비교 분석하였다. 평가 방법은 심리적인 방법으로 ACR 팬텀을 이용한 영상의 수치 값을 SPSS 통계프로그램을 이용하여 유의성과 신뢰도를 분석한 결과는 다음과 같다. 1. Fiber에서는 Screen-Film인 경우 3.9점, CR($50\;{\mu}m$)인 경우 4.2점, CR($100\;{\mu}m$)인 경우 3.2점, DR인 경우 4.2점을 얻어 CR($50\;{\mu}m$), DR, Screen-Film, CR($100\;{\mu}m$)순으로 높은 점수를 받았다(P<0.05). 2. Calcification은 Screen-Film인 경우 2.7점, CR($50\;{\mu}m$)인 경우 2.5점, CR($100\;{\mu}m$)인 경우 2.0점, DR인 경우 2.9점을 얻어 DR, Screen-Film, CR($50\;{\mu}m$), CR($100\;{\mu}m$) 순으로 높은 점수를 받았다(0.025(P<0.05). 3. Mass는 Screen-Film인 경우 3.8점, CR($50\;{\mu}m$)인 경우 3.8점, CR($100\;{\mu}m$)인 경우 3.6점, DR인 경우 4.5점을 얻어 DR, CR($50\;{\mu}m$), Screen-Film, CR($100\;{\mu}m$) 순으로 높은 점수를 받았다(P<0.1). 4. 합계점수 평가는 Screen-Film인 경우 10.4점, CR($50\;{\mu}m$)인 경우 10.6점, CR($100\;{\mu}m$)인 경우 8.7점, DR인 경우 11.3점을 얻어 DR, CR($50\;{\mu}m$), Screen-Film, CR($100\;{\mu}m$) 순으로 높은 점수를 받았다. 이상의 결과는 DR, Screen-Film시스템이 CR($100\;{\mu}m$)에 비해 화질이 우수하다는 것을 알 수 있다. 하지만 DR은 소자에 의한 불안정성, Screen-Film은 artifact에 의한 화질 저하 등 단점을 가지고 있으며, 화질 저하가 문제였던 CR시스템 중 Dual-Side방식의 CR($50\;{\mu}m$)을 사용한 경우에는 Screen-Film 시스템과 차이가 없는 것으로 나타났다. 향후 방사선 영상검사가 디지털화 되는 추세이므로 유방영상검사도 각 시스템의 발전과 보완이 필요할 것으로 사료된다.

• 대한방사선치료학회지
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• 제29권1호
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• pp.19-26
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• 2017

목 적: 양성자 치료계획에서 metal 재질의 fiducial marker에 의한 선량 계산오차를 최소화하려면 density override의 적용은 매우 중요하다. 하지만 실제 metal 재질로 density override을 할 경우 정확한 contouring 및 range compensator 제작에 어려움이 있기에 본 연구에서는 fiducial marker의 주변 재질로 density override를 시행하고 fiducial marker의 위치, 재질, beam의 개수에 따른 선량분포를 비교, 분석하여 평가하고자 한다. 대상 및 방법: Water phantom을 이용하여 fiducial marker의 위치를 proton beam의 최대 비정 끝에서부터 1.5, 2.5, 4.0, 6.0 cm로 설정하고 재질로는 gold, steel, titanium으로 설정하여 실제 metal 재질 및 주변 재질로 density override를 적용한 치료계획을 세웠다. 또한 본원에서 양성자치료를 받은 간암 환자 1명을 선정하여 proton beam의 최대 비정 끝에서부터 0, 1.5, 3.5 cm로 설정하고 재질로는 gold, steel, titanium으로 설정하여 치료계획을 세웠다. Fiducial marker의 재질, 위치 및 beam의 개수에 따른 PTV 내에 Homogeneity Index(HI), Conformity Index(CI), 종양에 가장 근접한 Organ At Risk(OAR)인 Esophagus의 maximum dose을 평가 지표로 설정하고 비교 분석하였다. 결 과: Water phantom 및 간암 환자를 대상으로 한 치료계획에서 fiducial marker의 위치에 따른 Homogeneity Index를 분석한 결과 실제 metal 재질로 density override 했을 때보다 주변 재질로 density override했을 때 Homogeneity Index가 감소했으며 주변 재질의 density override에서 하나의 beam에 대해서는 최대 비정 끝에서 멀리 위치할수록, 두 개 이상의 beam에서는 isocenter에 가까이 위치할수록 Homogeneity Index가 증가하였다. Fiducial marker의 위치에 따른 Conformity Index 및 종양 주위 OAR의 maximum dose를 분석한 결과 주변 재질로 density override 했을 때 Conformity Index는 1에 가까웠으며 OAR의 maximum dose는 크게 감소했다. 결 론: 일반적으로 임상에서 사용하는 작은 fiducial marker에 대해서 실제 metal 재질이 아닌 주변 재질로 density override 했을 때 선량 균등도 및 target coverage를 높이는 동시에 주변 정상조직에 대한 선량을 줄일 수 있었다. 따라서 fiducial marker을 최대한 피해서 치료계획을 세우는 것이 바람직하지만 beam path 상에 fiducial marker가 있는 경우 주변 재질의 density override 시행함으로써 보다 정밀한 양성자 치료 효과를 기대할 수 있을 것으로 사료된다.

• 전자공학회논문지
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• 제54권4호
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• pp.91-98
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• 2017

전기 임피던스 단층촬영 기법은 도메인의 표면에 부착된 전극들을 통해 주입된 전류와 측정된 전압 데이터를 기반으로, 미지의 도전율 분포를 복원하는 비파괴 기술이다. 이 논문에서는 전기 임피던스 단층촬영법에서 일반적 Tikhonov 조정을 갖는 역문제를 풀고 도전율 분포를 복원하기 위해 절단된 특이값 분해 기반의 역문제 해법을 제안하였다. 역문제 계산시간을 줄이기 위해 일반 조정행렬을 역행렬 항목에서 분리시키고 절단된 특이값 분해 방법을 적용하였다. 제안한 방법의 성능을 검증하기 위해 모의실험과 팬텀실험을 수행하고 복원결과를 비교하였다.

• 한국응용과학기술학회지
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• 제28권1호
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• pp.102-108
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• 2011

The study of wave propagation and scattering in biological media has become increasingly important in recent years. The propagation of light within tissues is an important problem that confronts the dosimetry of therapeutic laser delivery and the development of diagnostic spectroscopy. In the clinical application of photodynamic therapy(PDT) and in photobiology, the photon deposition within a tissue determines the spatial distribution of photochemical reactions. Scattered light is measured as a function of the distance (r) between the axis of the incident beam and the detection spot. Consequently, knowledge of the photosensitizer(Chlorophyll-a) function that characterizes a phantom is measured. To obtain the results of scattering coefficients(${\mu}s$) of a turbid material from diffusion described by experimental approach. It was measured the energy fluency of photon radiation at the position of penetration depth. From fluorescence experimental method obtained the analytical expression for the scattered light as the values of $(I/I_o)_{wavelength}$ vs the distance between the center of the incident beam and optical fiber in terms of the condition of "in situ spectroscopy(optically thick)" and real time by fluorometric measurements. The result was compromised with transport of intensities though a random distribution of scatters.

• 한국응용과학기술학회지
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• 제22권2호
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• pp.182-190
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• 2005

The propagation of light radiation within tissues is an important problem that confronts the dosimetry of therapeutic laser delivery and the development of diagnostic spectroscopy. In the clinical application of photodynamic therapy(PDT) and in photobiology, the photon deposition within a tissue determines the spatial distribution of photochemical reactions. Scattered light is measured as a function of the distance (r) between the axis of the incident beam and the detection spot. Consequently, knowledge of the photosensitizer(Chlorophyll-a) function that characterizes a phantom is important. To obtain the results of scattering coefficients(${\mu}s$) of a turbid material from diffusion described by experimental approach. It was measured the energy fluency of photon radiation at the position of penetration depth. From fluorescence experimental method obtained the analytical expression for the scattered light as the values of $(I\;/I_o)_{wavelength}$ vs the distance between the center of the incident beam and optical fiber in terms of the condition of "in situ spectroscopy(optically thick)" and real time by fluorometric measurements.

• 대한방사선기술학회지:방사선기술과학
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• 제19권1호
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• pp.81-87
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• 1996

When high energy photon beam is incident upon an air cavity interface the effect of ionization build-up observed. This phenomenon is resulting from the surface layers of the lesions are significant deficiency of electrons reaching the layers because of the replacement of solid scattering material by the air cavity, that is lack of electronic equilibrium. Measurement have been made in an acrylic phantom with a parallel plate chamber and high energy Photon beams, CO-60, 4MV, 6MV and 10MV X-rays have been investigated. The result of our study show that a significant effect was measured and was determined to be very dependent on field size, air cavity dimension and photon energy. The reductions were much larger for 10MV beam, underdosage at the interface was 12, 12.2, 16.9 and 20.6% for the CO-60, 4 MV, 6MV and 10MV, respectively. It was found that this non-equilibrium effect at the interface is more severe for the higher energy beams than that of lower energy beams and the larger cavity dimensions it is, the larger beam reductions we have. This problem is of clinical concern when lesions such as carcinoma beyond air cavities are irradiated, such as larynx, glottic and the patients with maxillectomy and ethmoidectomy and so forth.

• 대한의용생체공학회:의공학회지
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• 제35권5호
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• pp.142-150
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• 2014

The key to model-based iterative reconstruction (MBIR) algorithms for transmission computed tomography lies in the ability to accurately model the data formation process from the emitted photons produced in the transmission source to the measured photons at the detector. Therefore, accurately modeling the system matrix that accounts for the data formation process is a prerequisite for MBIR-based algorithms. In this work we compared quantitative performance of the three representative ray-driven methods for calculating the system matrix; the ray-tracing method (RTM), the distance-driven method (DDM), and the strip-area based method (SAM). We implemented the ordered-subsets separable surrogates (OS-SPS) algorithm using the three different models and performed simulation studies using a digital phantom. Our experimental results show that, in spite of the more advanced features in the SAM and DDM, the traditional RTM implemented in the OS-SPS algorithm with an edge-preserving regularizer out-performs the SAM and DDM in restoring complex edges in the underlying object. The performance of the RTM in smooth regions was also comparable to that of the SAM or DDM.

• 대한방사선기술학회지:방사선기술과학
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• 제42권4호
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• pp.265-270
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• 2019

Mammography is the most useful test for the early diagnosis of breast cancer. The MammoPad can be used for the purpose of reducing the pain felt by the patient due to the pressure of the breast. MammoPad cushion the pressure between the breasts and the equipment and reduce the patient's discomfort. A new material pad was fabricated to solve the problem of the H-pad which is currently in circulation. Quantitative evaluation of SNR and CNR and qualitative evaluation of imitation lesion using ACR Phantom were performed. In the quantitative evaluation, SNR and CNR of Non pad and Filter pad were not statistically significant.(p>0.05) In the qualitative evaluation, Fiber and Imitation lesion of H-pad and Filter pad were statistically significant(p<0.05), and all values of Calcification and Mass were not statistically significant. (p>0.05) In addition, Fiber, calcification, mass, and imitation lesion were not statistically significant in both Non pad and Filter pad.(p>0.05) Through this study, it was confirmed that the newly created Filter pad minimizes image quality degradation and can replace existing products.

• 로봇학회논문지
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• 제18권2호
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• pp.164-171
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• 2023

To control the spread of COVID-19, it is important to identify the infection in its incipient stages so that the infected persons can be dealt with accordingly. The currently used face to face sampling method may increase the risk of infection for medical professionals as it exposes them to the asymptomatic yet infectious patients. This can result in further increases in the load on the medical system and workload of the medical staff. As a solution to this problem, in this paper, we present a robotic system for rapid non-face-to-face automatic nasopharyngeal swab sample collection. The system consists of a custom designed 7-DoF manipulator equipped with a specially developed safety mechanism for restricting the maximum force applied by the tip of the swab. During the swab sampling process, the force applied by the tip of the swab is continuously monitored in real-time by a 3-axis force sensor in order to detect contact with the nasopharynx. The possibility of using this system for automaticnasopharyngeal swab sample collection is proven through experimentation with a phantom model.

• 대한의용생체공학회:의공학회지
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• 제30권1호
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• pp.56-65
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• 2009

Compton imaging is often recognized as a potentially more valuable 3-D technique in nuclear medicine than conventional emission tomography. Due to inherent computational limitations, however, it has been of a difficult problem to reconstruct images with good accuracy. In this work we show that the row-action maximum likelihood algorithm (RAMLA), which have proven useful for conventional tomographic reconstruction, can also be applied to the problem of 3-D reconstruction of cone-beam projections from Compton scattered data. The major advantage of RAMLA is that it converges to a true maximum likelihood solution at an order of magnitude faster than the standard expectation maximiation (EM) algorithm. For our simulations, we first model a Compton camera system consisting of the three pairs of scatterer and absorber detectors placed at x-, y- and z-axes, and generate conical projection data using a software phantom. We then compare the quantitative performance of RAMLA and EM reconstructions in terms of the percentage error. The net conclusion based on our experimental results is that the RAMLA applied to Compton camera reconstruction significantly outperforms the EM algorithm in convergence rate; while computational costs of one iteration of RAMLA and EM are about the same, one iteration of RAMLA performs as well as 128 iterations of EM.