• 한방안이비인후피부과학회지
• /
• 제27권4호
• /
• pp.110-120
• /
• 2014

Objectives : We performed a clinical study to investigate autonomic conditions in persistent allergic rhinitis depending on various pattern identifications and the availability of heart rate variability (HRV) as a pattern identification diagnostic tool. Methods : 32 patients with persistent allergic rhinitis were asked to interview with doctor of Korean Medicine and perform the four pattern questionnaires (Cold-Heat Pattern, Phlegm Pattern, Yin Deficiency pattern, bloodstasis pattern). Then, they were examined their autonomic conditions with heart rate variability test. Results : Patients were classified as three pattern groups (Lung-stomach heat, Lung qi deficiency cold, Lung-spleen qi deficiency) by doctor. In the Lung qi deficiency cold group, Total power of the HRV (TP) and the power of the low frequency component (LF) significantly higher than in the Lung-stomach heat or Lung-spleen qi deficiency group (P < 0.05). Also, Patients were classified as 8 pattern groups (Cold/Heat, Phlegm/Non-phlegm, Yin deficiency/Non-yin deficiency, Bloodstasis/Non-bloodstasis) by four pattern questionnaires. Only in the Yin deficiency group, the power of the low frequency component (LF) significantly lower than in the Non-yin deficiency group (P < 0.05). There were not any significant differences in the rest groups. Conclusions : The result may provide that HRV doesn't reflect well the differences in the various pattern groups, and the HRV's availability is low. Continuous studies are needed to develop the objective and standardized pattern identification diagnostic tool for allergic rhinitis.

• Clinical and Experimental Pediatrics
• /
• 제58권5호
• /
• pp.190-193
• /
• 2015

Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity lung disease due to bronchial colonization of Aspergillus fumigatus that occurs in susceptible patients with asthma or cystic fibrosis. A 10-year-old girl was referred to the Department of Pediatric Pulmonology for persistent consolidations on chest radiography. Pulmonary consolidations were observed in the right upper and left lower lobes and were not resolved with a 4-week prescription of broad-spectrum antibiotics. The patient had a history of atopic dermatitis and allergic rhinitis but no history of asthma. She had no fever but produced thick and greenish sputum. Her breathing sounds were clear. On laboratory testing, her total blood eosinophil count was $1,412/mm^3$ and total serum IgE level was 2,200 kU/L. Aspergillus was isolated in the sputum culture. The A. fumigatus-specific IgE level was 15.4 kU/L, and the Aspergillus antibody test was also positive. A chest computed tomography scan demonstrated bronchial wall thickening and consolidation without bronchiectasis. An antifungal agent was added but resulted in no improvement of pulmonary consolidations after 3 weeks. Pulmonary function test was normal. Methacholine provocation test was performed, revealing bronchial hyperreactivity ($PC_{20}=5.31mg/mL$). Although the patient had no history of asthma or bronchiectasis, ABPA-seropositivity was suspected. Oral prednisolone (1 mg/kg/day) combined with antifungal therapy was started. Pulmonary consolidations began decreasing after 1 week of treatment and completely resolved after 1 month. This is the first observed and treated case of seropositive ABPA in Korean children without previously documented asthma.

• 대한한방소아과학회지
• /
• 제12권1호
• /
• pp.77-94
• /
• 1998

Chronic cough is one of the most common respiratory symptoms, especially in children. And it can be the sale presenting manifestation of bronchial asthma. Although most coughs are self limiting, chronic cough often proves to be a frustrating problem. It is commonly defined as a persistent or recurrent cough exceeding 3weeks duration. The post nasal syndrome has been determined to be the most common cause of chronic cough, followed by asthma, chronic bronchitis, gastroesophageal reflux and bronchiectasis. This study was performed at both City-Oriental Medicine Hospital and Pundang Cha Oriental Medicine Hospital from January,1,1998 to November 31,1998, and 114 children with chronic cough persisting for longer than 3 weeks were evaluated. We investigated the clinical findings and evaluated the etiology in children with chronic cough syndrome including: type of cough (with or with out sputum and daily onset) and associated signs & symptoms. The results were as follows: The most common cause of chronic cough was asthma with sinusitis (27.2%); The second and third were post nasal drip syndrome(22.8%) and bronchial hypereactivitic cough(14.9%). The other causes included asthma, paranasal sinusitis, bronchitis and rhinitis. Therefore, in the diagnostic and therapeutic approach to this symptom, it should be considered that the cause of this type of cough is either bronchus and pulmonary disease or that associated with another problem, especially sinusitis, gastroesophageal reflux and allergic disease. Also, in infants and toddlers, congenital abnormaly should be considered.

• Tuberculosis and Respiratory Diseases
• /
• 제44권1호
• /
• pp.146-153
• /
• 1997

연구배경 : 만성기침은 비흡연 성인호흡기환자의 14% - 23%에서 관찰되는 흔한 호흡기 증상이다. 만성기침의 원인으로는 후비루증후군이 가장 흔하며 기침형 천식도 만성기침 환자의 29%에서 보고되고 있지만 우리나라의 정확한 통계는 없다. 이에 저자들은 기관지과민성을 측정하여 만성기침의 원인이 되는 후비루 증후군, 기침형 천식, 단순 기관지염의 빈도를 조사하였고, 각 질환군에서 아토피와 흡연의 영향을 분석하였다. 대상 및 방법 : 3주이상의 만성기침을 주소로 내원하여 흉부청진과 단순 흉부사진에서 정상소견을 보이는 46명의 만성기침 환자와 기관지천식 환자 45명, 알레르기성비염 환자 16명, 정상대조군 25명을 대상으로 병력의 문진, 진찰소견, 폐기능 검사, 비특이적 기관지 유발검사, 즉시형 피부반응검사를 시행하였고 단순 흉부사진 및 부비동 사진을 촬영하였다. 결 과 : 만성기침 환자에서 기침형 천식은 17.4%, 단순기관지염은 21.7%, 후비루 증후군은 35%, 원인을 규명하지 못한 경우가 25.9% 였다. 만성기침환자중 기관지 과민반응의 양성율은 35% 로 정상 대조군과 알레르기성 비염군과 비교하여 의미있게 기관지 과민성이 증가되어 있었고, 후비루 증후군이 있는 환자중 44% 에서 기관지 과민반응에 양성이었다. 만성기침환자에서 기관지 과민성에 영향을 주는 요인으로 동반된 호흡기 증상의 유무와 관련성 있는 경향을 보일뿐, 후비루 증후군, 코증상, 흡연, 폐환기 기능이상, 피부반응검사, 부비동염의 유무와는 무관하였다. 또한 각 질환군에서 아토피나 흡연과의 연관성은 없었다. 결 론 : 만성기침환자는 정상대조군과 알레르기성 비염에 비해 기관지 과민성이 증가되어 있었으나 기관지 과민성에 영향을 주는 요인은 호흡기 증상의 유무만이 관련성 있는 경향을 보였으며 아토피와 흡연과의 연관성은 관찰할 수 없었다.