• Title/Summary/Keyword: Permeability

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Intestinal Permeabilities of Polyethylene Glycols (330-1122D) in the In Situ Perfused Rat (장내 관류된 동물에서 Polyethylene Glycols에 의한 장내 투과율 (Intestinal Permeability)측정에 관한 연구)

  • 김미혜
    • Journal of Nutrition and Health
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    • v.29 no.2
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    • pp.153-158
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    • 1996
  • Polyethylene glycols(PEGs)are hydrophilic molecules that have been used to characterize intestinal permeability via the paracellular pathway. Using a mixture of PEGs(400, 600 and 1000), containing oligomers in the molecular weight range 330 to 1122 D, the molecular weight permeability dependence in the jejunum of the rat small intestine was examined, employing an in situ recirculation perfusion technique. Individual oligomers were determined by HPLC with refractive detection. In the range studied, a distinct molecular weight cut-off was not apparent. Corrected for the length of jejunum used in the study, over the molecular weight range 330 to 1122D, the apparent permeability(Papp) of PEG ranged from 4.92$\pm$0.02$\times$10-5cm/sec(mean$\pm$SEM, n=5) to 0.28$\times$10-5cm/sec. Also, it was observed that the apparent permeability was inversely proportional to approximately MW2. The results in this study suggest that molecular weight is an important factor in determining the intestinal permeability.

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Applicability Evaluation of the Characteristics Equation for a Coefficient of Permeability of Unsaturated Soils (불포화토의 투수계수 방정식의 적용성 평가)

  • Lyu, Tae-Jin;Song, Chang-Seob;Lim, Seong-Yoon
    • Proceedings of the Korean Society of Agricultural Engineers Conference
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    • 2005.10a
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    • pp.393-398
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    • 2005
  • In order to treat flow problems for an unsaturated soils, it is required the mediation of the coefficient of permeability with variation of suction. The coefficient of permeability for soils can be determined by the direct or indirect methods. The direct methods of permeability can be performed either in the laboratory or in the field. The indirect methods can be predicted from the soil-water characteristics curve. Laboratory test methods to measure the coefficient of permeability can be categorized into two types, steady-state and unsteady-state. In this study, the coefficient of permeability for unsaturated soils was determined by the modified apparatus for steady state-method(Klute, 1972) and was predicted from the equations of Brooks and Corey(1964) and Van Genuchten(1980). Experimental results were compared with predicted coefficient of permeability and verified applicability of the two equations.

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Permeability Characteristics of Clays with Various pH Values (pH 변화에 따른 점토의 투수특성)

  • 장병욱;강상욱;김성필;차경섭
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.44 no.6
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    • pp.99-105
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    • 2002
  • A series of physical properties and rigid wall permeability tests were performed on two clays to investigate changes in permeability characteristics of clays with various pH values. Results of the study are as follows. As pH values were increased, coefficients of permeability of S-clay(clay fraction 18%) and J-clay(clay fraction 30%) were decreased in 3 and 4 times, respectively. Variation of coefficient of permeability of J-clay was considerably related to clay fraction. It can be said that coefficient of permeability of clays tested was increased, as pH values were decreased. This was because of increase in effective voids caused by decrease in thickness of diffused double layer, that is, change in soil structures and effective grain sizes.

Studies on Corneal Penetration of P-Hydroxybenzoic Acid Esters

  • Lee, Chi-Ho;Lee, Kyoung-Jin;Yun, Il;Shin, Young-Hee
    • Archives of Pharmacal Research
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    • v.14 no.4
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    • pp.311-318
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    • 1991
  • Corneal permeability of various n-alkyl p-hydroxybenzoates (parabens) was studied in vitro using excised rabbit corneas, and the effect of lipophilicity of parabens on the corneal permeability was also investigated. Permeability coefficients were obtained from the least-square linear regression after the steady state had been reached. Lipophilicity of parabens was calculated by distribution coefficients determined in octanol-S | $12{\phi}{\parallel}$) rensen's buffer solution (pH 5.0). The relationship between lipophilicity and corneal permeability of parabens was not linear, but the optimum lipophilicity for the maximum permeation was found. The influence of tween 80 on corneal permeability of methyl and butylparaben was not significant.

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Nondestructive Evaluation for Remanent Life of 1Cr-0.5Mo Steel by Reversible Permeability

  • Ryu, Kwon-Sang;Lee, Yun-Hee;Park, Jong-Seo;Baek, Un-Bong
    • Journal of Magnetics
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    • v.17 no.3
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    • pp.206-209
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    • 2012
  • Peak interval for reversible permeability is presented for nondestructively evaluating the remanent life of 1Cr-0.5Mo steel. The method to measure the peak interval of reversible permeability is based on the value of reversible permeability is the same as the differential value of the hysteresis loop. The measurement principle is based on the first harmonics voltage induced in a sensing coil using a lock-in amplifier tuned to a frequency of the exciting voltage. Results obtained for the peak interval of reversible permeability and Rockwell hardness on the aged samples decrease as aging time and the Larson-Miller parameter increase. We could estimate the remanent life of 1Cr-0.5Mo steel by using the relationship between the peak interval of reversible permeability and the Larson-Miller parameter, nondestructively.

Identification of the strain-dependent coefficient of permeability by combining the results of experimental and numerical oedometer tests with free lateral movement

  • Balic, Anis;Hadzalic, Emina;Dolarevic, Samir
    • Coupled systems mechanics
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    • v.11 no.1
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    • pp.1-14
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    • 2022
  • The key parameter that affects the consolidation process of soil is the coefficient of permeability. The common assumption in the consolidation analysis is that the coefficient of permeability is porosity-dependent. However, various authors suggest that the strain-dependency of the coefficient of permeability should also be taken into account. In this paper, we present results of experimental and numerical analyses, with an aim to determine the strain-dependency of the coefficient of permeability. We present in detail both the experimental procedure and the finite element formulation of the two-dimensional axisymmetric numerical model of the oedometer test (standard and modified). We perform a set of experimental standard and modified oedometer tests. We use these experimental results to validate our numerical model and to define the model input parameter. Finally, by combining the experimental and numerical results, we propose the expression for the strain-dependent coefficient of permeability.

Effect of Sonication on Permeability of Filter Paper (필터재 투과성 효율 증대를 위한 초음파의 활용)

  • 오세헌;황명기;김형수;김영욱
    • Proceedings of the Korean Geotechical Society Conference
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    • 2003.03a
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    • pp.647-654
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    • 2003
  • This study investigated the effect of ultrasound on the permeability of the filter paper The investigation involves laboratory experiments, and the laboratory tests were conducted under abroad range of conditions Including energy levels of ultrasonic waves, time for treatment, and temperature. The results of the study show that sonication enhances the permeability of the filter paper significantly. The degree of enhancement varies with sonication power and duration of application. The effect of sonication on permeability with temperature variation and concentration of the test specimens seems not to be significant.

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Chloride Permeability of High Strength Concrete (고강도 콘크리트의 염화물 침투특성)

  • ;;;Kawano, Hirotaka
    • Proceedings of the Korea Concrete Institute Conference
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    • 2001.05a
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    • pp.985-990
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    • 2001
  • Chloride permeability of high strength concrete(HSC) was investigated using saltwater pending test and rapid chloride permeability test by electrical potential(ASTM C 1202). The lower water-cement ratio concrete showed the lower diffusion coefficient of chloride. The relationship between the diffusion coefficient of chloride and charge passed by the rapid chloride permeability test could be obtained. This relationship appears to be an effective method for evaluating chloride permeability of low water-cement HSC.

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Permeability of Latex Modified Concrete (라텍스 개질 콘크리트의 투수특성)

  • 이종명;윤경구;최상릉;홍창우;전인구
    • Proceedings of the Korea Concrete Institute Conference
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    • 2000.10a
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    • pp.191-196
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    • 2000
  • This study was focused on the investigation of permeability of latex modified concrete as the latex content variated such as 5%, 10%, 15%, and 20%. The rapid chloride permeability test was used to evaluate the relative permeability of latex-modified concretes and conventional concretes. The results showed that the permeability of latex-modified concretes was considerably lower than conventional concretes tested, which may be due to the latex filled in voids and interconnections of hydrated cement and aggregates by a film of latex particles.

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Characteristics of Saturated Hydraulic Conductivity in Steel Making Slag and Sludge according to Mixing Rate of Bentonite (벤토나이트 혼합율에 따른 제강 슬래그 및 슬러지의 투수 특성 변화)

  • Woo, Won-Jae
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.3 no.1
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    • pp.52-61
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    • 2000
  • Permeability is important factor in the geotechnical problems, such as seepage discharge and dissipation of excess pore water pressure. The Kozeny-Carman equation works well for graded soils but serious discrepancies are found in clays. Major factor for these discrepancies is the tortuous flow path and unequal pore size. To estimate the permeability of fine grained soils, a permeability equation in which swelling potential is coupled with Kozeny-Carman equation is proposed in this study. To verify proposed equation, a series of variable head permeability test was carried out for steel making slag and sludge mixed with bentonite. The coefficients of permeability which is measured in the laboratory is compared with the values by the proposed equation. From the comparison, it is shown that the proposed equation can predict the coefficient of permeability of clays with satisfaction. As steel making slag and sludge is industry waste, it is reused as material of road foundation and cement but the rate of use is low. It mixed sodium-bentonite with high swelling property and permeability decrease effect. Then, Admixture investigates reuse possibility as liner of waste fill.

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