• Journal of the Institute of Convergence Signal Processing
• /
• v.16 no.2
• /
• pp.35-39
• /
• 2015

Auditory and visual stimuli presented in the peripheral visual field were perceived as spatially coincident when the auditory stimulus was presented five to seven degrees outwards from the direction of the visual stimulus. Furthermore, judgments of the perceived distance between auditory and visual stimuli presented in the periphery did not increase when an auditory stimulus was presented in the peripheral side of the visual stimulus. As to the origin of this phenomenon, there would seem to be two possibilities. One is that the participants could not perceptually distinguish the distance on the peripheral side because of the limitation of accuracy perception. The other is that the participants could distinguish the distances, but could not evaluate them because of the insufficient experimental setup of auditory stimuli. In order to confirm which of these two alternative explanations is valid, we conducted an experiment similar to that of our previous study using a sufficient number of loudspeakers for the presentation of auditory stimuli. Results revealed that judgments of perceived distance increased on the peripheral side. This indicates that we can perceive discrimination between audio and visual stimuli on the peripheral side.

• Journal of Korean Ophthalmic Optics Society
• /
• v.20 no.2
• /
• pp.157-165
• /
• 2015

Purpose: To evaluate changes in central and peripheral refraction along the horizontal visual fields in myopic corneal refractive surgery group compared with emmetropes. Methods: One hundred twenty eyes of 60 subjects ($23.56{\pm}2.54$ years, range: 20 to 29) who underwent myopic refractive surgery and 40 eyes of 20 emmetropes ($22.50{\pm}1.74$ years, range: 20 to 25) were enrolled. The central and peripheral refractions were measured along the horizontal meridianat $5^{\circ}$, $10^{\circ}$, $15^{\circ}$, $20^{\circ}$, $25^{\circ}$ in the nasal and temporal areas using an open-field autorefractor. For analysis of post-op group, the group was classified by pre-op spherical equivalents of < -6.00 D and ${\geq}-6.00D$ as two post-op groups. Results: Pre-op spherical equivalent was $-4.56{\pm}0.92D$ (rang: -2.50 to -5.58 D) in post-op group 1, and $-7.09{\pm}0.96D$ (rang: -6.00 to -9.00 D) in post-op group 2. Spherical equivalent (M) in the emmetropes ranged from $-0.20{\pm}0.22D$ at center to $-0.64{\pm}0.83D$ at $25^{\circ}$ in the temporal visual field and to $-0.20{\pm}0.67D$ at $25^{\circ}$ in the nasal visual field; M in post-op group 1 ranged from $-0.16{\pm}0.29D$ at center to $-5.29{\pm}1.82D$ at $25^{\circ}$ in the temporal visual field and to $-4.48{\pm}1.88D$ at $25^{\circ}$ in the nasal visual field; M in post-op group 2 ranged from $-0.20{\pm}0.32D$ at center to $-7.98{\pm}2.08D$ at $25^{\circ}$ in the temporal visual field and to $-7.90{\pm}2.26D$ at $25^{\circ}$ in the nasal visual field. Among the three groups, there was no significant difference in M at central visual field (p=0.600) and at $5^{\circ}$ in the temporal visual field (p=0.647), whereas, there was significant difference in M at paracentral and peripheral visual field (p=0.000). Conclusions: Emmetropes had relatively constant refractive errors throughout the central and peripheral visual field and showed myopic peripheral defocus along the horizontal visual field. On the other hand, in myopic corneal refractive surgery group, there were significant differences in refractive errors between the central and peripheral visual field compared with differences in the central and peripheral refraction patterns of emmetropes.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.33 no.2
• /
• pp.130-139
• /
• 2020

Objectives : The aim of this study is to report the effect of Korean Medicine Treatment for patient with ophthalmoplegia in Miller-Fisher Syndrome. Methods : A patient with ophthalmoplegia treated with herbal medicine, cupping therapy and acupuncture(including pharmacopuncture, electroacupuncture). We used photographs of eye movement to evaluate the changes in symptoms, Scott and Kraft score of left eye, visual field test for measuring peripheral visual field, subjective symptom, and VAS for headache, subjective symptom. Results : After treatment, Scott and Kraft score increase from -4 to -2. Visual field of left side improved from 45° to 80°. Also, other symptoms such as diploma, dizziness, headache, gait disturbance was also improved. There are no adverse effects and no relapse of ophthalmoplegia after 20 days of discharge. Conclusions : This case report suggests that Korean Medicine Treatment can be effective for patient with ophthalmoplegia in Miller-Fisher Syndrome.

• Journal of Korean Ophthalmic Optics Society
• /
• v.15 no.2
• /
• pp.151-154
• /
• 2010

Purpose: We investigated how the movement of iris and visual axis affects the finite schematic eye Methods: Using the schematic eye with the crystalline lens in the existing forms of the radial GRIN and the spherical GRIN, the iris centre was moved 0.5 mm in nasal direction and visual axis was tilted $5^{\circ}$ in same direction, with the additional degree of 2.5 down to locate the focal point in fovea. This study analyzed performance change of the optical system, designing it same as the real eye. Results: The whole aberration distribution showed a considerable difference in performance in comparison with the real eye; the biggest difference shown at the central field of optical system. The spherical aberration showed the biggest difference, and a peripheral power error and field curvature leaned toward (+) direction in aberration distribution. Conclusions: When designing the schematic eye with the performance similar with that of the real eye by taking into consideration the iris centre and visual axis, the aberration at the center field of optical system in particular should be corrected. Spherical aberration which showed the biggest difference should be corrected in the first place. In addition, a peripheral power error and field curvature that leaned toward (+) direction should be moved toward (-) direction.

• Journal of Korean Institute of Industrial Engineers
• /
• v.19 no.2
• /
• pp.53-64
• /
• 1993

Successful completion of a visual task in a predetermined time is very crucial to many operations such as piloting an aircraft. Although existing ergonomic interface models often provide a function of vision tests, it determines only the visibility at any given location. To complement this problem in existing models, the isoresponse time region considering the factors related to visual tasks is presented. Using a multiple regression model, equal response time regions were obtained within which mean response time is expected to be the same and is asymmetrical in shape. Among the factors considered, expectancy significantly decreased response time, and when cued, the effects of field heterogeneity, target uncertainty, density, size contrast and peripheral position on search time were less significant than those in unexpected cases. Response time and error rate, gender and visual acuity were not significantly correlated, and response time and age was positively correlated. These results are expected to be directly applicable to designing various visual tasks in real-life situations.

• Journal of the Institute of Convergence Signal Processing
• /
• v.11 no.2
• /
• pp.132-136
• /
• 2010

Psychophysical experiment was performed to investigate how audio-visual spatial disparity affects on perceptual space in peripheral vision. In the experiment, participants were exposed to two stimuli of vision and sound which comes simultaneously from different directions, respectively. The visual stimulus was implemented by 7 white LEDs which were located at an equal distance with 7 different angles of $-70^{\circ}$, $-40^{\circ}$, $-20^{\circ}$, $0^{\circ}$, $20^{\circ}$, $40^{\circ}$, and $70^{\circ}$ from the right front. Those audial stimuli were also implemented by loudspeakers which were placed at 9 different directions equally spaced by $5^{\circ}$ ranged from $-20^{\circ}$ to $20^{\circ}$. Each participant then evaluated spatial disparity between visual and audial stimuli with 5 levels of response, in which the higher level indicates the larger gap. When the visual stimulus is applied from the right, the results show that the response level gets higher for a larger angle between visual and auditory stimuli. A similar tendency for the visual stimulus with $0^{\circ}$ orientation was also be observed. On the other hand, when the visual stimulus is applied from the left, the response level gets lower for the larger angle.

• Journal of Korean Ophthalmic Optics Society
• /
• v.18 no.4
• /
• pp.503-507
• /
• 2013

Purpose: This study was to design wide angle mobile camera corrected optical distortion for peripheral area, which were reduced optical distortion and TV distortion by using 4 aspherical lenses. Methods: The optical design was satisfied with ${\pm}1%$ optical distortion in viewing angle of $95^{\circ}$ and total length of optical system was less than 4.5 mm which was considering a thickness of mobile camera. 1/3.2 inch (5M) CCD sensor was used in the optical system and set design condition to satisfy MTF which was over than 20% in 140 lp/mm. Results: Optimized wide angle mobile camera showed ${\pm}1%$ optical distortion in full field of $95^{\circ}$ viewing angle and TV distortion was 0.46% so that distortion of peripheral area was reduce. MTF showed over than 20% in every field. Ray aberration and astigmatism were small amount so that it showed stable performance. Conclusions: Obtain wider and clearer view which is reduced image distortion of surrounding area via optical method in wide angle mobile camera which has wider view angle than current mobile camera. And it was able to fix a demerit when it occurred via software correction. It is able to apply to study of camera which is related to spectacles.

• Journal of Korean Ophthalmic Optics Society
• /
• v.7 no.1
• /
• pp.9-13
• /
• 2002

It is well known that the maximum amplitude of accommodation decreases with increasing age.(Presbyopia). With single vision lenses presbyopia can be corrected only for one viewing distance. With progressive power lenses presbyopia can be corrected for all viewing distances. But there are some other changes in the visual system with age which can not be corrected by spectacle lenses. Pupillary diameter decreases and the light transmission of the ocular media decreases. Therefore old people need more light, they need better illumination. Cone density in the retina decreases, this is only one example for changes in the sensory system. These changes in the visual system cause changes in visual functions. At the age of 80 visual acuity has decreased to half. Contrast sensitivity for gratings decreases mainly for high spatial frequencies very important is the increase of stray light in the ocular media and therefore the increase of glare. Veiling luminance increases by a multiple of approximately 4, Dark adaptation gets slower and light sensitivity is approximately 2 log units (factor 100) less when the eye is completely dark adapted. Also colour vision gets worse, especially at low luminances. Elderly people have problems with visual tasks which require divided attention between foveal and peripheral vision. An example is the measurement of the useful field of view. This useful field of view be expanded (improved) by visual training.

• Archives of Plastic Surgery
• /
• v.44 no.6
• /
• pp.482-489
• /
• 2017

Background Polydeoxyribonucleotide (PDRN) is known to have anti-inflammatory and angiogenic effects and to accelerate wound healing. The aim of this study was to investigate whether PDRN could improve peripheral tissue oxygenation and angiogenesis in diabetic foot ulcers. Methods This was a prospective randomized controlled clinical trial. Twenty patients with a non-healing diabetic foot ulcer were randomly distributed into a control group (n=10) and a PDRN group (n=10). Initial surgical debridement and secondary surgical procedures such as a split-thickness skin graft, primary closure, or local flap were performed. Between the initial surgical debridement and secondary surgical procedures, 0.9% normal saline (3 mL) or PDRN was injected for 2 weeks by the intramuscular (1 ampule, 3 mL, 5.625 mg, 5 days per week) and perilesional routes (1 ampule, 3 mL, 5.625 mg, 2 days per week). Transcutaneous oxygen tension ($TcPO_2$) was evaluated using the Periflux System 5000 with $TcPO_2/CO_2$ unit 5040 before the injections and on days 1, 3, 7, 14, and 28 after the start of the injections. A pathologic review (hematoxylin and eosin stain) of the debrided specimens was conducted by a pathologist, and vessel density (average number of vessels per visual field) was calculated. Results Compared with the control group, the PDRN-treated group showed improvements in peripheral tissue oxygenation on day 7 (P<0.01), day 14 (P<0.001), and day 28 (P<0.001). The pathologic review of the specimens from the PDRN group showed increased angiogenesis and improved inflammation compared with the control group. No statistically significant difference was found between the control group and the PDRN group in terms of vessel density (P=0.094). Complete healing was achieved in every patient. Conclusions In this study, PDRN improved peripheral tissue oxygenation. Moreover, PDRN is thought to be effective in improving inflammation and angiogenesis in diabetic foot ulcers.

• Anatomy and Cell Biology
• /
• v.55 no.2
• /
• pp.217-228
• /
• 2022

Vigabatrin (VGB) is an effective antiepileptic drug used mainly to treat infantile spasms and refractory complex partial seizures. However, using VGB was restricted as it was known to cause retinal toxicity that appears as a severe peripheral visual field defect. Accordingly, this study was conducted to examine the histopathological and biochemical effects of VGB on the retina in adult male albino rats and assess the possible therapeutic role of mesenchymal stem cells (MSCs) against this potential toxicity. The rats were divided into three groups (control group, VGB group, and VGB/MSCs group), one week after 65 days of VGB treatment ±MSCs. The right eyeballs were prepared for histological and immunohistochemical examination, whereas the left eyeballs were prepared for real-time polymerase chain reaction analysis. Our results demonstrated that MSCs ameliorated retinal pathological changes and downregulated the expression of glial fibrillary acidic protein, vascular endothelial growth factor, and synaptophysin after VGB administration suggesting MSCs function and vascular modulating effect. Moreover, MSCs regulate retinal tissue gene expression of BAX, Bcl-2, BDNF, NGF, synapsin, interleukin (IL)-6, IL-1β, and occludin suggesting MSCs antiapoptotic and immunomodulating effect. In conclusion, MSCs administration could be a suitable therapeutic line to ameliorate VGB-induced retinopathy.