• Applied Microscopy
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• v.3 no.1
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• pp.29-38
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• 1973

Introduction. The human cutaneous scars manifest themselves many ways in different types according to the factors such as the age, sex, race of the patient as well as the location,. kind and heal ing process of the wound. Among the scars it is quiet difficult to verify the clinical course of the hypertrophic or keloidal scars from the true keloids. However, clinical observations indicate that stress, either mechanical or in the forms of chronic infections, can induce a functional change in the fibroblasts causing an excessive production of collagenous matrix. In this study, we preliminary attempt to justify any difference of the cellular structure between keloids and hypertrophic scars by using electron microscope. Material and Methods. A total of 23 cases: 2 scars, 2 hypertrophic scars and 19 keloids are examined. Immediately, the biopsy tissue was fixed in 10% neutral formalin and 4% glutaraldehyde solution in phosphate buffer for 4 hours, post fixed in 1 % osmium tetraoxide for two hours, dehydrated with graded alcohol, and embedded in Epon 812. Thick sections were stained with hematoxylin eosin, periodic acid-Schiff(PAS) and Van Gieson stain. Thin sections were cut and uranyle acetate, lead citratestain and examined with the electron microscope. Result. The morphologic features of keloid showed thick, homogenously eosinophilic bands of collagen and numberous large active fibroblasts. The hypertrophic scar and soft scar are more cellular than keloid and composed thinner collagenous fiber. For this paper in the etiology of keloids can not as be defined, but and interesting keloidal tissue fibroblast showed irregular nucleus with irregular shape dense bodies and fibril materials contained in to the cytoplasm.

• Advances in aircraft and spacecraft science
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• v.2 no.1
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• pp.95-108
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• 2015

Automatic Dependent Surveillance Broadcast (ADS-B) is quickly being adopted by aviation safety authorities around the world as the standard for aircraft tracking. The technology provides the opportunity for live tracking of aircraft positions within range of an ADS-B receiver stations. Currently these receiver stations are bound by land and local infrastructural constraints. As such there is little to no coverage over oceans and poles, over which many commercial flights routinely travel. A low cost space based ADS-B receiving system is proposed as a constellation of small satellites. The possibility for a link between aircraft and satellite is dependent primarily on proximity. Calculating the likelihood of a link between two moving targets when considering with the non-periodic and non-uniform nature of actual aircraft flight-paths is non-trivial. This analysis of the link likelihood and the performance of the tracking ability of the satellite constellation has been carried out by a direct simulation of satellites and aircraft. Parameters defining the constellation (satellite numbers, orbit size and shape, orbit configuration) were varied between reasonable limits. The recent MH370 disappearance was simulated and potential tracking and coverage was analysed using an example constellation. The trend of more satellites at a higher altitude inclined at 60 degrees was found to be the optimal solution.

• Journal of Institute of Control, Robotics and Systems
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• v.11 no.11
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• pp.956-962
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• 2005

This paper presents an integrated analysis of production and financing decisions. We assume that a cash storage unit is installed to manage the cash flows related with production activities such as raw material procurement, process operating setup, Inventory holding cost and finished product sales. Temporarily financial investments are allowed for more profit. The production plant is modeled by the Batch-Storage Network with Recycle Streams in Yi and Reklaitis (2003). The objective function of the optimization is minimizing the opportunity costs of annualized capital investment and cash/material inventory while maximizing stockholder's benefit. No depletion of all the material and cash storage units is major constraints of the optimization. A novel production and inventory analysis formulation, the PSW(Periodic Square Wave) model, provides useful expressions for the upper/lower bounds and average level of the cash and material inventory holdups. The expressions for the Kuhn-Tucker conditions of the optimization problem can be reduced to two subproblems and analytical lot sizing equations under a mild assumption about the cash flow pattern of stockholder's dividend. The first subproblem is a separable concave minimization network flow problem whose solution yields the average material flow rates through the networks. The second subproblem determines the decisions about financial Investment. Finally, production and financial transaction lot sizes and startup times can be determined by analytical expressions as far as the average flow rates are calculated. The optimal production lot and storage sizes considering financial factors are smaller than those without such consideration. An illustrative example is presented to demonstrate the results obtainable using this approach.

• The korean journal of orthodontics
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• v.23 no.1 s.40
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• pp.17-35
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• 1993

We tried to evaluate frequencies and severities of malocclusion of various socioeconomic areas according to growth and development. To obtain objective validity, we used Handicapping Labiolingual Deviation (HLD) suggested by Draker, Treatment Priority Index (TPI) by Grainger, Handicapped Malocclusion Assessing Record (HMAR) by American Dental Association and American Association of Orthodontist. Seoul and Kwangju were selected as an urban group, Ahnyang as an middle socioeconomic group and Hwasun near the Kwangju area as an rural group. 140 (male 63, female 73) of 5th grade in 'E' elementary school students in Seoul, 202 (male 101, female 101) of 'S' elementary school students in Kwangju, 207(male 105, female 102) of 'H' elementary school students in Hwasun, and 100(male 49, female 51) of 'M' elementary school students of in Ahnyang of all the same grade were analyzed and we obtained the results as follows; 1. TPI, HLD, and HMAR showed high coincidence and reproducibility between different observer. (p<0.01) 2. In comparison of TPI, HLD, and HMAR according to clinical decision, there was statistically difference between each other. (p<0.01) 3. As the severity of malocclusion increases there was high correlation between TPI and HLD, and between HLD and HMAR (p<0.05) 4. With respect to differences between areas in TPI and HLD, there was statistically difference between Ahnyang and other areas. 5. In Seoul as an urban group there was a high incidence of periodic checkup and history of orthodontic treatment than other area. 6. Mode of feeding and posture during sleeping did not affect the severity of malocclusion. As a conclusion, TPI, HLD and HMAR are so reproducible and coincident that they can be used as a guide on evaluating the frequency and severity of malocclusion and determining the priority of orthodontic treatment to determine the need and supply of orthodontic treatment. Furthermore these indices can provide objectively valid data for establishing public health problem solution.

• Journal of Ocean Engineering and Technology
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• v.24 no.6
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• pp.51-60
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• 2010

In this study, the performance evaluation of a conventional wave resonator at the entrance of a port or a pier against secondary undulation has been performed using 2D hydrodynamic modeling within port. A wave resonator has been designed for the attenuation of the secondary undulation induced by the long-periodic waves. The controlled performance of the wave resonator has been numerically investigated for CGWAVE MODULE of finite-element model of SMS (Surface water Modeling System) based on the elliptic mild-slope wave equation. SMS was verified though the comparisons with analytical solution performed by Ippen and Goda (1963). Also, It was confirmed that a wave resonator of a rectangular model harbor is effective enough to control the secondary undulation when it compares variation of water level with the case of no resonance system. From the above results, amplification phenomenon induced by long-period waves transferred from 1900 sec to 2100 sec when it applied a wave resonator in Busan Gamcheon Port which is a deep-sea. And it was confirmed that a wave resonator of Pohang New Port attenuates largely long-period waves which are within the range of 300 sec induced by long-period motion of the moored ship.

• Journal of the Korean Institute of Telematics and Electronics
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• v.27 no.10
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• pp.124-129
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• 1990

This paper describes a new method to eliminate some selected harmonics (5,7,11) in PWM waveforms using Walsh and related orthogonal functions. Previous analyses of PWM waveforms are based on the nonlinear equations requiring iterative solution methods which are not practical in real-time systems. In addition, synthesis of low harmonics waveform at high power system is not easy to implement with power electronic hardware. The goal of this paper is to achieve the harmonics elimination in a PWM waveform by replacing the nonlinear equations in Fourier analysis with linear algebraic equations resulting from the use of orthogonal Walsh equation. This paper also describes how to synthesize low ordered harmonic waveforms with practical power electronic hardware. Walsh and Radmacher functions are easily manipulated by Harmuth's array generator, and those algorithms are accurate, computationally efficient and faster than algorithm based on Fourier analysis. In addition, this method is simulated to synthesize periodic PWM waveforms. From the experi-mental results, it is shown that single-phase PWM waveform are identified with the proposed method. And these methods are also extended to three-phase PWM waveforms in this paper.

• Natural Product Sciences
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• v.19 no.4
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• pp.290-296
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• 2013

In preliminary tests, we examined the effect of several fractions isolated from fermented pine needle extract on pacemaker potentials in cultured interstitial cells of Cajal (ICCs) from the mouse colon using a whole cell patch clamp technique. Among these fractions, Fraction 3 (F3) elicited the most powerful depolarization of membrane. Therefore, the aim of the present study was to investigate the effect of F3 obtained from fermented extract of Pinus densiflora needle on pacemaker potentials in ICCs and to establish its mechanism of action. Colonic ICCs generated spontaneous periodic pacemaker potentials in the current-clamp mode. F3 depolarized the membrane and decreased the frequency and amplitude of pacemaker potentials in a dose-dependent fashion. The F3-induced effects on pacemaker potentials were blocked by methoctramine, a muscarinic $M_2$ receptor antagonist, and by glycopyrrolate, a muscarinic $M_3$ receptor antagonist. The F3-induced effects on pacemaker potentials were blocked by external $Na^+$-free solution and by flufenamic acid, a non-selective cation channel blocker, as well as by the removal of external $Ca^{2+}$ and in the presence of thapsigargin, a $Ca^{2+}$-ATPase inhibitor in the endoplasmic reticulum. Taken together, these results suggest that F3 of pine needle extract modulates the pacemaker activity of colonic ICCs by the activation of non-selective cation channels via muscarinic $M_2$ and $M_3$ receptors. And external $Ca^{2+}$ influx and intracellular $Ca^{2+}$ release are involved in F3 actions on ICCs.

• Journal of Institute of Control, Robotics and Systems
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• v.10 no.6
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• pp.537-544
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• 2004

An effective methodology is reported for determining the optimal lot size of batch processing and storage networks which include uncertain demand forecasting. We assume that any given storage unit can store one material type which can be purchased from suppliers, internally produced, infernally consumed, transported to or from other sites and/or sold to customers. We further assume that a storage unit is connected to all processing and transportation stages that consume/produce or move the material to which that storage unit is dedicated. Each processing stage transforms a set of feedstock materials or intermediates into a set of products with constant conversion factors. A batch transportation process can transfer one material or multiple materials at once between sites. The objective for optimization is to minimize the probability averaged total cost composed of raw material procurement, processing setup, transportation setup and inventory holding costs as well as the capital costs of processing stages and storage units. A novel production and inventory analysis formulation, the PSW(Periodic Square Wave) model, provides useful expressions for the upper/lower bounds and average level of the storage inventory. The expressions for the Kuhn-Tucker conditions of the optimization problem can be reduced to two sub-problems. The first yields analytical solutions for determining lot sires while the second is a separable concave minimization network flow subproblem whose solution yields the average material flow rates through the networks for the given demand forecast scenario. The result of this study will contribute to the optimal design and operation of the global supply chain.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.9
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• pp.3-11
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• 2016

Vehicle to Everything (V2X) communication has been growing to enhance traffic safety by employing advanced wireless communication systems. V2X communication is one core solution for governing and advancing future traffic safety and mobility. In this paper, we design the system level simulator (SLS) of Long Term Evolution (LTE)-based V2X and propose the adaptive transmission scheme for vehicle communication. The proposed scheme allocates the resource randomly in time and frequency domain, and transmit the message according to probability of transmission. The performance analysis is based on freeway case in periodic message transmission. Simulation results show that proposed scheme can improve the cumulative distribution function (CDF) of packet reception ratio (PRR) and average PRR.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.37 no.3B
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• pp.189-203
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• 2012

In cognitive radio networks, a secondary user opportunistically accesses an empty channel based on periodic sensing results for avoiding possible interference to the primary users. However, local sensing does not guarantee the full protection of the primary users because hidden primary receivers may exist within the interference range of the secondary transmitter. To protect primary systems and simultaneously to maximize utilization of the secondary users, we need to derive carefully designed coexistence solutions for various network scenarios. In this paper, we propose coexistence conditions without any harmful interference in accordance with the uplink/downlink schedule and user position. We have classified the coexistence conditions into four different scenario cases depending on the provided information to the secondary network basestations. Computer simulation results demonstrated that the proposed method can be applied to the real cognitive radio system to improve the communication probability of CR devices.