• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제21권3호
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• pp.184-188
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• 2018

Purpose: Despite the increasing incidence of pediatric Crohn disease (CD) in Korea, data on the characteristics of perianal lesions are scarce. Therefore, we aimed to investigate the characteristics of pediatric CD with accompanying perianal lesions in Korea. Methods: We retrospectively reviewed the medical records of children (age ${\leq}18$ years) with confirmed CD at Gachon University Gil Medical Center between 2000 and 2014. Patients were classified into two groups based on the presence or absence of any perianal lesions including skin tags. Additional analysis was performed according to the presence or absence of perianal perforating lesions. Results: Among the 69 CD children (mean age, 15.4 years) include in the analysis, 54 (78.3%) had a perianal lesion and 29 (42.0%) had a perianal perforating lesion. The median duration of chief complaints was longer in pediatric CD with any accompanying perianal lesions (5.40 months vs. 1.89 months, p=0.02), while there was no difference between pediatric CD with and without perianal perforating lesions (5.48 months vs. 4.02 months, p=0.18). Perianal symptoms preceded gastrointestinal symptoms in 13 of 29 (44.8%) patients with perianal perforating lesions. Conclusions: CD should be suspected in children with perianal lesions, even in circumstances when gastrointestinal symptoms are absent.

• Advances in pediatric surgery
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• 제16권1호
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• pp.32-36
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• 2010

Condyloma acuminatum is an uncommon disease but there is an increased incidence reported in recent years in prepubertal children. Anal and perianal condyloma accuminatum in children may suggest sexual abuse and treatment should include the thorough social evaluation as well as medical treatment. A 25 month old girl presented with multiple sessile nodules around her anal and perianal area, Biopsy confirmed the diagnosis of condyloma accuminatum. There was no definite evidence of sexual abuse, but her father had condyloma accuminatum involving his penis. The patient's lesions were excised totally. At three week follow up there was no anal stricture but there were newly developed small lesions around perianal area. Imiquimod onit was applied for 2 weeks and the recurred lesion disappeared completely. At postoperative 5 month, the operative area was fully epithelialized without recurrence.

• Advances in pediatric surgery
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• 제8권2호
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• pp.133-137
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• 2002

To evaluate the clinical characteristics and results of treatment of fistula-in-ano and perianal abscess in childhood, we analyzed 95 cases of fistula-in-ano and/or perianal abscess seen in childhood, between January 1995 and June 2001 at the Department of General Surgery of Ewha Womans University Mokdong Hospital. Perianal abscess was in 25 patients, anal fistula in 62 and combined disease (perianal fistula and abscess) in 8. Male predominance was noted (95%). Median age was 8 months and 78% of cases were presented under the age of 1 year. Median duration of symptoms was 60 days. Twenty four abscesses (77%) and 18 lesions (72%) of combined disease (n=25) were located on both lateral sides of the anus, and fistulas located on both lateral sides were 33 (53%). Multiplicity of the lesion was noted in 25% of cases. Sixteen percent of abscess, 81% of fistula and 88% of combination group have had previous perianal abscesses. The perianal abscesses were treated with incision and currettage and fistulas were treated with fistulotomy or fistulectomy. There were no recurrent diseases and no complications after surgical treatment. Although the progresses of the perianal abscess and fistula in ano in childhood may be self-limitied, surgical management was safe and curable.

• 한국임상수의학회지
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• 제27권6호
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• pp.746-750
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• 2010

세 마리의 군 사역견이 신체검사와 직장 검사 등을 통해 항문주위 누공으로 진단되었다. 초기 치료는 단기간의 싸이클로스포린과 케토코나졸과 0.1%의 타크로리무스 연고제제로 시작하였다. 병변이 거의 다 치료가 되었을 시점부터 0.1% 타크로리무스 연고제제를 도포 횟수를 줄여서 실시하였다. 세 마리 모두에서 병변은 2-8주 사이에 별다른 부작용을 동반하지 않고 거의 대부분 사라졌으며, 완치는 증례 1, 2, 3에서 각 13, 6, 4주에 이루어졌다. 이 세가지 약물의 병용 프로토콜은 항문낭과도 연결된 항문주위 누공에서도 병변을 해소하는데 효과적이었으며, 특히 초기에 빠른 병변의 해소에 도움이 되어 병변으로부터 발생되는 고통을 경감시켜주는 기간이 늘어나는 것이 강점이라고 할 수 있다. 또한 시간적인 측면 외에도 경제적인 측면에서도 도움이 되므로 개에서 발생하는 항문주위 누공에 효과적인 치료 프로토콜로 유용하게 사용될 수 있을 것으로 사료된다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제8권1호
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• pp.70-75
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• 2005

저자들은 기존의 크론병 치료에 호전이 없었던 항문 주위 병변에 0.3 mg/g의 저농도 tacrolimus 연고제를 1일 2회 환부에 도포하는 방법으로 약물에 의한 부작용 발생 없이 병변의 현저한 호전을 보인 3례를 경험하였기에 보고하는 바이다.

• Neonatal Medicine
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• 제15권2호
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• pp.172-175
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• 2008

혈관종은 신생아기에 가장 흔한 양성 종양으로 60% 이상이 두경부에 위치하며 예후가 좋으나 회음부나 항문 주위에 위치한 혈관종은 통증, 출혈, 반복적인 감염 및 궤양과 같은 합병증이 자주 동반된다. 특히 항문 주위에 위치한 혈관종에서 발생한 궤양은 스테로이드나 레이저등 다양한 치료에도 호전되지 않는 경우가 있다. 저자들은 일반적인 집중치료에 호전되지 않아 대장창냄술을 실시하였고 이후 궤양이 호전되는 과정을 경험하였기에 이를 보고하는 바이다.

• Parasites, Hosts and Diseases
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• 제56권5호
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• pp.487-489
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• 2018

Phthirus pubis usually infests the pubis, groin, buttocks and perianal region. It can sometimes infest the thighs, abdomen, chest, axillae and beard. Eyelashes and eyebrows may be involved in children. The involvement of the scalp is very rare. We describe a case of P. pubis infestation located exclusively on the scalp in an adult woman. Neither lice/nits nor skin lesions were observed elsewhere, including eyebrows, eyelashes, axillae, pubis, buttocks and perianal region (the patient was hairless in the axillae and pubis). A review of the literature is enclosed.

• Journal of Yeungnam Medical Science
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• 제40권4호
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• pp.423-425
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• 2023

Porokeratosis ptychotropica is an uncommon form of porokeratosis, which was initially described in 1995. It is clinically characterized by symmetrical reddish to brown-colored hyperkeratotic, verrucous, or psoriasiform plaques on the perianal and gluteal regions. The lesions tend to integrate and expand centrally, with small peripheral satellite lesions. Early skin biopsy and appropriate diagnosis are essential because malignant change occurs in 7.5% of porokeratotic lesions. Conventional treatment options include topical steroid, retinoid, imiquimod, 5-fluorouracil, isotretinoin, excimer laser, photodynamic therapy, intralesional steroid or bleomycin injection, cryotherapy, carbon dioxide (CO₂) laser, and dermatome and excision, but none seem to achieve complete clearance. A 68-year-old woman presented with diffuse hyperkeratotic scaly lichenoid plaques on the buttocks that had persisted for several years. A skin biopsy of the buttocks revealed multiple cornoid lamellae and intense hyperkeratosis. There were some dyskeratotic cells beneath the cornoid lamellae and the granular layer was absent. Porokeratosis ptychotropica was diagnosed based on the characteristic clinical appearance and typical histopathological manifestations. She was treated with a CO₂ laser in one session and topical application of urea and imiquimod cream for 1 month. The lesions slightly improved at the 1-month follow-up. We herein present a rare case of porokeratosis ptychotropica.

• Korean Journal of Radiology
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• 제23권8호
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• pp.785-793
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• 2022

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease involving apocrine-bearing sites. It is characterized by recurrent painful nodules and abscesses that potentially rupture, resulting in sinus tract formation, fistulas, and scarring. HS tends to be found in the intertriginous areas (i.e., the axillary, inguinal, and perianal areas of the body). HS may be uncommon for radiologists because its diagnosis is usually based on clinical assessment. However, diagnosis based solely on clinical manifestations can underestimate the severity of HS. Ultrasonography and MRI play a critical adjunct role in determining the severity and extent of the disease and greatly aid its management. Given that MRI is an effective imaging tool, its role in the analysis of severe and anogenital HS lesions merits considerable attention. Unfortunately, anoperineal HS imposes diagnostic dilemmas. It has multiple symptoms and presentations and often mimics other diseases in the intertriginous areas. Therefore, a thorough understanding of HS is essential to avoid delayed diagnoses. This review highlights the typical MRI imaging features and staging of HS, emphasizing on the anoperineal location. The review also differentiates the disease from mimics to facilitate the prompt delivery of appropriate treatment and improve patients' quality of life.

• 한국임상수의학회지
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• 제30권3호
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• pp.210-213
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• 2013

고양이 헤르페스 바이러스-1 감염과 관련된 고양이의 괴사성 안면 피부염의 증례를 보고하고자 한다. 3살된, 미거세 수컷 도메스틱 숏헤어 고양이가 2년간 지속된 소양성 피부염을 주증으로 내원하였다. 환자는 생후 약 2개월령부터 지속적인 눈꼽과 결막염을 가지고 있었으며, 눈 주위부터 안면 전체로 확대된 피부염의 병력을 가지고 있었다. 내원 당시에는 가피로 덮여있는 미란과 궤양성의 피부병변이 안면과 회음부에서 주로 관찰되었다. 피부 병변부위의 조직학적 검사 결과, 경계면 피부염을 동반한 기저층의 수포변성과 각질세포의 단세포 괴사 소견이 관찰되었으며, 호산구 침윤을 동반한 표피와 진피의 괴사와 각질세포의 핵내 봉입체도 관찰되었다. 이에 가피 부위의 가검물을 이용하여 PCR검사를 수행하였고, 그 결과 고양이 헤르페스 바이러스-1의 유전자가 검출되었다. 위의 소견으로부터, 본 증례는 고양이 헤르페스 바이러스-1 감염과 관련된 궤양성 피부염으로 진단되었고, 아시클로버의 경구투여와 고양이 인터페론 오메가의 국소투여로 피부 및 점막 병변의 뚜렷한 개선을 볼 수 있었다.