Recently, the problem of air pollution has become a global concern due to industrialization and overcrowding. Air pollution can cause various adverse effects on human health, among which respiratory diseases such as asthma, which have been of interest in this study, can be directly affected. Previous studies have used clinical data to identify how air pollutant affect diseases such as asthma based on relatively small samples. This is high likely to result in inconsistent results for each collection samples, and has significant limitations in that research is difficult for anyone other than the medical profession. In this study, the main focus was on predicting the actual asthmatic occurrence, based on data on the atmospheric environment data released by the government and the frequency of asthma outbreaks. First of all, this study verified the significant effects of each air pollutant with a time lag on the outbreak of asthma through the time-lag Pearson Correlation Coefficient. Second, train data built on the basis of verification results are utilized in Deep Learning algorithms, and models optimized for predicting the asthmatic occurrence are designed. The average error rate of the model was about 11.86%, indicating superior performance compared to other machine learning-based algorithms. The proposed model can be used for efficiency in the national insurance system and health budget management, and can also provide efficiency in the deployment and supply of medical personnel in hospitals. And it can also contribute to the promotion of national health through early warning of the risk of outbreak by atmospheric environment for chronic asthma patients.
Kim, Il-Man;Lee, Chang Young;Son, Eun Ik;Kim, Dong Won;Yim, Man Bin;Kim, Sang Pyo
Journal of Korean Neurosurgical Society
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v.30
no.3
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pp.334-341
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2001
Objective : We have currently changed treatment strategies to methotrexate(MTX)-based preirradiation chemotherapy with subsequent planned radiation for the initial therapy of primary central nervous system lymphoma (PCNSL). The aim of this study was to evaluate the results of treating PCNSL with chemotherapy plus radiotherapy (CRT) or radiotherapy(RT) alone. Method and Material : This study involved 10 females and 3 males patients with a mean age of 54.2 years. All patients underwent surgery, open(8 cases) or stereotactic biopsy(5 cases) for histological diagnosis. Eleven tumors were diffuse large B-cell lymphomas. Tumor volume change in the follow-up images and survival time were evaluated in patients treated with CRT and RT alone. In the beginning, two patients received ProMACE-Cytabom chemotherapeutic regimen, but did not complete the course and died of progressive tumor 8 and 9 months after diagnosis, respectively. One patient died at 6 months before chemotherapy. These three were excluded from the survival analysis. Five patients(RT group) completed full courses of cranial irradiation with or without boost. For the current combined modality treatment, high-dose MTXbased chemotherapy(systemic and intrathecal MTX, IV vincristine, and oral procarbazine) followed by whole brain irrdiation to 45Gy to tumor was introduced in 5 patients of CRT group. Result : A complete response was achieved in three of five who received RT only and in all of five who received CRT. All patients in CRT groups are in disease free status at a mean 23 months following therapy. The RT group patients refused any additional salvage therapy at tumor relapse and survived at mean 20 months from diagnosis. The Karnofsky performance status improved in eight of ten patients with treatment. The treatment toxicity included leukoencephalopathy in RT group and severe leukopenia, transient hepatitis, avascular necrosis of femoral head, hearing loss, and amenorrhea in CRT group, respectively. Conclusion : The combined modality therapy of MTX-based chemotherapy plus radiotherapy for PCNSL may enhance tumor response and improve patient survival. The patients who received CRT should be carefully followed up because of the higher risk of treatment-induced late neurotoxicity.
Journal of the Korea Academia-Industrial cooperation Society
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v.16
no.3
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pp.2242-2248
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2015
The damages from greenhouses collapsing due to heavy snowfall in winter are increasing, and the current frames of greenhouse are required to be improved. This study was conducted to seek solutions to improve intensities of greenhouse frame to bear heavy snows. We investigated a structural safety of greenhouses by calculating axial force, bending moment and combined stress when snow load was increased up to 30% of the current standard ground snow load of the conventional greenhouse types (07-single type 3, 07-single type 18) in the three regions (Gyeongju, Sokcho, and Gangneung) where were most damaged by recent heavy snows. In addition, we determined what structural type was most efficiently bear snow loads by measuring the differences between the load bearing strength according to the changes of tube diameter and thickness or the rafter spacing of greenhouses circular pipe. MIDAS GEN program was used in the analysis. As a result, with the snow load increase of 30%, greenhouse in Gyongju was still safe, but in Sokcho was at a risk, and in Gangneung was possible to be collapsed even in the current snow load. Increased pipe diameter than increased pipe thickness was more efficient in terms of improved performance of greenhouse structure. Accordingly, it is suggested to revise standards of greenhouse to increase pipe diameter of rafter for minimizing damages by heavy snow.
Journal of the Korea Academia-Industrial cooperation Society
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v.19
no.4
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pp.674-682
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2018
Large industrial motors require a large area because of the high risk of shutdown accidents and large industrial accidents due to the lowering of the dielectric strength of the armature windings and overheating problems. Therefore, there is a demand for a large-capacity motor that has small size, light weight, and excellent dielectric strength compared with conventional motors. Superconducting motors have advantages of high efficiency and output power, low size, low weight, and improved stability. This results from greatly increasing the magnetic field generation by using superconductive field coils in rotating machines such as generators and motors. It is very important to design and analyze the cooling system to lower the critical temperature of the wires to achieve superconducting performance. In this study, a field loss analysis and low-temperature heat transfer analysis of the cooling system were performed through the conceptual design of a 100-HP high-temperature superconducting synchronous motor. The field loss analysis shows that a uniform pore magnetic flux density appears when high-temperature superconducting wire is used. The low-temperature heat transfer analysis for gaseous neon and liquid neon showed that a flow rate of 1 kg/min of liquid neon is suitable for maintaining low-temperature stability of the high-temperature superconducting wire.
Kim, Myung-Soo;Lee, Ji-Hae;Ha, Bo-Ram;Lee, Re-Na;Lee, Kyung-Ja;Suh, Hyun-Suk
Radiation Oncology Journal
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v.29
no.3
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pp.181-190
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2011
Purpose: Thoracic radiotherapy is a major treatment modality of stage III non-small cell lung cancer. The normal lung tissue is sensitive to radiation and radiation pneumonitis is the most important dose-limiting complication of thoracic radiation therapy. This study was performed to identify the clinical and dosimetric parameters related to the risk of radiation pneumonitis after definitive radiotherapy in stage III non-small cell cancer patients. Materials and Methods: The medical records were reviewed for 49 patients who completed definitive radiation therapy for locally advanced non-small cell lung cancer from August 2000 to February 2010. Radiation therapy was delivered with the daily dose of 1.8 Gy to 2.0 Gy and the total radiation dose ranged from 50.0 Gy to 70.2 Gy (median, 61.2 Gy). Elective nodal irradiation was delivered at a dose of 45.0 Gy to 50.0 Gy. Seven patients (14.3%) were treated with radiation therapy alone and forty two patients (85.7%) were treated with chemotherapy either sequentially or concurrently. Results: Twenty-five cases (51.0%) out of 49 cases experienced radiation pneumonitis. According to the radiation pneumonitis grade, 10 (20.4%) were grade 1, 9 (18.4%) were grade 2, 4 (8.2%) were grade 3, and 2 (4.1%) were grade 4. In the univariate analyses, no clinical factors including age, sex, performance status, smoking history, underlying lung disease, tumor location, total radiation dose and chemotherapy were associated with grade ${\geq}2$ radiation pneumonitis. In the subgroup analysis of the chemotherapy group, concurrent rather than sequential chemotherapy was significantly related to grade ${\geq}2$ radiation pneumonitis comparing sequential chemotherapy. In the univariate analysis with dosimetric factors, mean lung dose (MLD), $V_{20}$, $V_{30}$, $V_{40}$, MLDipsi, $V_{20}$ipsi, $V_{30}$ipsi, and $V_{40}$ipsi were associated with grade ${\geq}2$ radiation pneumonitis. In addition, multivariate analysis showed that MLD and V30 were independent predicting factors for grade ${\geq}2$ radiation pneumonitis. Conclusion: Concurrent chemotherapy, MLD and $V_{30}$ were statistically significant predictors of grade ${\geq}2$ radiation pneumonitis in patients with stage III non-small cell lung cancer undergoing definitive radiotherapy. The cutoff values for MLD and $V_{30}$ were 16 Gy and 18%, respectively.
Kececioglu, Mehmet;Seckin, Berna;Baser, Eralp;Togrul, Cihan;Kececioglu, Tugban Seckin;Cicek, Mahmut Nedim;Gungor, Tayfun
Asian Pacific Journal of Cancer Prevention
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v.14
no.1
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pp.511-514
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2013
Background: A small but significant proportion of cases with atypical squamous cells of undetermined significance (ASCUS) may harbour CIN 2-3, or even invasive carcinoma. Although immediate colposcopy, HPV-DNA testing or expectant management are three recommended options in ASCUS triage, a consensus does not currently exist on which one of these approaches is the most efficient. In this study, we aimed to compare the performance and cost of immediate colposcopy and colposcopy based on the human papillomavirus (HPV) testing for detecting histologically confirmed high-grade cervical intraepithelial neoplasia (CIN) in women with ASCUS. Materials and Methods: Records of 594 women with an index Papanicolaou smear showing ASCUS were retrospectively analyzed. Women in the immediate colposcopy arm were referred directly to colposcopy (immediate colposcopy group, n=255) and those in the HPV triage arm were proceeded to colposcopy if the high-risk HPV (hrHPV) test was positive (HPV triage group, n=339). High grade CIN (CIN2+) detection rate and treatment costs were compared between the groups. Results: The detected rate of CIN2+ was higher in the HPV triage group compared to immediate colposcopy group (8% vs. 1.6%, p=0.011). In the HPV triage group, the total cost, cost per patient, and the cost for detecting one case of high grade CIN were higher than the immediate colposcopy group (p<0.001). Conclusions: In women with ASCUS cytology, HPV DNA testing followed by colposcopy is more costly than immediate colposcopy, but this approach is associated with a higher rate of CIN2+ detection. This findings suggest that HPV DNA testing combined with cervical cytology could reduce the referral rate to colposcopy.
This longitudinal quasi-experimental research was conducted to develop parent role education program and to evaluate the effect of this program for mother-infant interaction, childrearing environment and infant development. The subjects were the healthy infants weighing over 2,500gm at birth, whose gestational age was more than 37weeks, and their healthy mothers. The sample consisted of eighteen mother-infant dyads for intervention group and sixteen dyads for control group. Data were collected from March 15th in 1999 to Jun 20th in 2000. The intervention group received programmed education consisted of discharge education, telephone counselling, and home visiting care. But control group were collected data without programmed education. In this study, the Nursing Child Assessment Teaching Scale(NCATS) devised by Barnard was used to determine the mother-infant interaction, HOME was used to determine the childrearing environment, and Griffiths mental development scale was used to determine the infant development. The data were analyzed using SPSS Win using chi-square test, t-test, and repeated measure ANOVA. This study was focused on the results of twelve months time point. Summaries of the results were as follows: 1. There was no significant difference in mother-infant interaction(NCATS) between intervention group and control group. But both of two groups showed significantly higher in interaction score at twelve months than at six months in the subscales of social-emotional growth fostering, and responsiveness to caregiver. 2. There was no significant difference in childrearing environment(HOME) between two groups at twelve months. But when each subscale of HOME was examined, intervention group showed higher scores in the dimensions of maternal involvement with child(p=.001), and maternal emotional-verbal responsivity(p=.048). 3. There was no significant difference in GQ of the Griffiths mental development scale between two groups, although significant difference was found in performance subscale. 4. Infant development at twelve months showed significant correlation with mother-infant interaction and childrearing environment at six months, although mother-infant interaction and childrearing environment at twelve months did not show significant correlations with infant development at twelve months. 5. Developmental scores at six months showed significant correlations with variety in daily stimulation, and mother's emotional, verbal responsivity, whereas developmental scores at twelve months showed significant correlations with acceptance of child behavior at six months, and appropriate play material at twelve months. In conclusion, the maternal education program for primipara showed long term effect in some categories in organizing the childrearing environment, and fostering the infant development. We suggest further study and implications of parent role education program for high risk parents such as parents in low economic status or with premature babies.
From among the NDT (nondestructive testing) methods, the MFL (magnetic flux leakage) method is specially suitable for testing pipelines because pipeline has high magnetic permeability. The system applied to MFL method is called the MFL PIG. The previous MFL PIG showed high performance in detecting the metal loss and corrosions. However, MFL PIG is highly unlikely to detect the cracks which occur by exterior-interior pressure difference in pipelines and the shape of crack is long and very narrow. In MFL PIG, the magnetic field is performed axially and there is no changes of cross-sectional area at cracks that the magnetic field passes through. Cracks occur frequently in the pipelines and the risk of the accident from the cracks is higher than that from the metal loss and corrosions. Therefore, the new PIG is needed to be researched and developed for detecting the cracks. The circumferential MFL (CMFL) PIG performs magnetic fields circumferentially and can maximize the magnetic flux leakage at the cracks. In this paper, CMFL PIG is designed and the distribution of the magnetic fields is analyzed by using 3 dimensional nonlinear finite element method (FEM). In CMFL PIG, cracks, standards of NACE, are detectable. To estimate the shape of crack, the leakage of magnetic fields for many kinds of cracks is analyzed and the method is developed by signal processing.
Most banks in Myanmar have begun to provide their services via mobile phones. However, few studies investigated the factors that may help to set mobile services from a customer perspective. So, this study aims to propose and test a conceptual research model to predict the user's intention to use and actual use level of mobile banking service by combining UTAUT and DeLone-Mclean IS model. Data were collected from 206 citizens who had experienced mobile banking in various regions of Myanmar. The study found that performance expectancy, effort expectancy, information quality and service quality influence the user 's intention to adopt mobile banking services which directly affects the user's actual use of them. However, social influence, facilitating condition and system quality don't influence the user's intention. The study results contribute to meeting customer's needs and reducing customer risk in Myanmar's mobile banking industry, suggesting to seamlessly provide the necessary resources like technology improvements, organizational infrastructure and service centers. Another future study are required to include service's security and trust factors so that the service providers could gain their customers' reliability and trust.
Journal of the Institute of Electronics and Information Engineers
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v.50
no.2
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pp.221-231
/
2013
Exchanging personal health information(PHI) is an essential process of healthcare services using information and communication technology. But the process have the inherent risk of information disclosure, so the PHI should be protected to ensure the reliability of healthcare services. In this paper, we designed encryption module for wearable personal health devices(PHD). A main goal is to guarantee that the real-time encoded and transmitted PHI cannot be allowed to be read, revised and utilized without user's permission. To achieve this, encryption algorithms as DES and 3DES were implemented in modules operating in Telos Rev B(16bit RISC, 8Mhz). And the experiments were performed in order to evaluate the performance of encryption and decryption using vital-sign measured by PHD. As experimental results, an block encryption was measured the followings: DES required 1.802 ms and 3DES required 6.683 ms. Also, we verified the interoperability among heterogeneous devices by testing that the encrypted data in Telos could be decoded in other machines without errors. In conclusion, the encryption module is the method that a PHD user is given the powerful right to decide for authority of accessing his PHI, so it is expected to contribute the trusted healthcare service distribution.
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