• 제목/요약/키워드: Performance guidelines

검색결과 1,185건 처리시간 0.029초

Vancomycin 초기 투여 용량 개선 방안 (Development of Vancomycin Initial Dosage Guidelines to Achieve New Target Ranges)

  • 유재영;김정현;이용원;김은영;손기호
    • 한국임상약학회지
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    • 제20권3호
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    • pp.221-228
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    • 2010
  • In 2009, American Journal of Health-System Pharmacy (AJHP) recommended that targeting vancomycin trough concentrations of 10 mg/L or more because of therapeutic failure and potential risk of developing vancomycin resistance. Therefore, new dosage guidelines that could achieve to these higher target were needed. The aims of this study were to develop dosage guidelines targeting new vancomycin trough concentration and to evaluate the performance of these new guidelines. All data analysis were performed using NONMEM(R). Population pharmacokinetic model was first developed from vancomycin dosage and concentration data collected retrospectively during routine therapeutic drug monitoring in 441 patients, then new vancomycin dosage guidelines were developed by using the model to predict vancomycin trough and peak concentrations in a simulated dataset. The estimates, such as, vancomycin concentration trough level, time to achieve target level, mean error were performed to evaluate and compare difference between conventional dosage and new dosage guidelines. The proposed dosage guidelines were predicted to achieve 43.5% of vancomycin trough level within 10~20 mg/L, which is significantly higher than current guidelines (26.3%). Time to achieve target trough level was 19.4 hours in new guidelines comparing to 93.1 hours in the conventional dosage. Thus, new vancomycin dosage guidelines have been developed to achieve new target trough concentrations earlier and more consistently than conventional guidelines.

동력분산형 고속전철의 충돌안전도 설계 가이드라인 도출 (Derivation of the Standard Design Guidelines for Crashworthiness of the High-Speed EMU)

  • 김거영;조현직;구정서
    • 한국철도학회:학술대회논문집
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    • 한국철도학회 2008년도 춘계학술대회 논문집
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    • pp.772-779
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    • 2008
  • Through this study, standard design guidelines for the high speed EMU have been derived to meet the crashworthiness requirements of the Korean rollingstock safety regulation. The crashworthiness regulation requires some performance requirements for two heavy collision accident scenarios; a train-to-train collision at the relative speed of 36 kph, and a collision against a standard deformable obstacle of 15 ton at 110 kph. The complete train set will be composed of 2TC-6M with 13 ton axle load, different from KTX with the power car of 17 ton axle load. Using theoretical and numerical analyses, some crashworthy design guidelines were derived in terms of mean crush forces and energy absorptions for main crushable structures and devices. The derived design guidelines were evaluated and improved using one dimensional spring-mass dynamic simulations. It is shown from the simulation results that the suggested design guidelines can easily satisfy the domestic crashworthiness requirements.

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Performance-Based Seismic Design of Reinforced Concrete Building Structures Using Inelastic Displacements Criteria

  • Kabeyaswa, Toshimi
    • 한국지진공학회논문집
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    • 제2권3호
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    • pp.61-71
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    • 1998
  • A performance-based seismic design method for reinforced concrete building structures being developed in Japan is outlined. Technical and scientific background of the performance-based design philosophy as well as recently developed seismic design guidelines are is presented, in which maximum displacement response to design earthquake motion is used as the limit-state design criteria. A method of estimating dynamic response displacement of the structures based on static nonlinear analysis is described. A theoretical estimation of nonlinear dynamic response considering the characteristics of energy input to the system is described in detail, which may be used as the standard method in the new performance-based code. A desing philosophy not only satisfying the criteria but also evaluating seismic capacity of the structures is also introduced.

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성능위주 연기제어 설계지침 분석 (Analysis of Performance-based Design Guides of Smoke Control System)

  • 김정엽
    • 한국화재소방학회논문지
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    • 제30권4호
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    • pp.6-13
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    • 2016
  • 건축물에서의 연기제어 시스템과 관련하여 국내에서는 거실에 대한 배연기준과 피난계단 및 부속실에 대한 제연기준이 제시되고 있으나, 대형화 고층화 복합화 되어가는 첨단 건축물에 대한 적용성을 검토하면 국내 설계기준에 따른 연기제어 시스템은 화재시 연기안전을 확보하기 곤란할 수 있다. 따라서 대형 고층 복합의 첨단 건축물에 대한 화재시 연기안전성을 높이고 화재와 건축물 특성에 따른 상호 연기제어 연계성 확보와 통합적 설계가 가능한 성능위주 연기제어의 적용이 요구된다. 본 논문에서는 국내 연기제어 기준을 분석하고 개선이 필요한 부분을 제시하였으며, 선진외국에서의 성능위주 설계 수행에 대한 법체계와 성능위주 연기제어 설계의 지침을 조사하고 분석하였다.

국내 경관계획 관련지침 및 계획내용 분석 (Analysis of Guidelines and Content of Visual Landscape Planning in Korea)

  • 주신하;김영희
    • 한국조경학회지
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    • 제39권4호
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    • pp.1-10
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    • 2011
  • 본 연구는 경관법 제정 이후 경관법에 의한 경관계획 관련지침과 경관계획의 내용을 분석하여 경관계획 진행사항과 문제점을 파악하고, 이에 대한 개선방안을 제안하고자 하였다. 경관계획의 특정을 살펴보기 위해 경관계획 수립 시 기초가 되는 경관계획수립지침과 경관계획보고서를 비교 분석하였다. 경관계획수립지침 분석은 실제 경관계획을 수립한 전문가를 대상으로 설문조사를 실시하였으며, 중요도-성취도 분석기법을 활용하여 각 단계별 지침 내용의 유효성과 현실적용 정도 등을 분석하였다. 경관계획보고서 분석은 법정계획으로 기본경관계획이 이미 수립된 자치단체 중 광역시, 시, 군별로 각 2곳을 선정하여 총 6개의 경관계획 보고서를 경관계획수립지침을 기준으로 분석하였다. 본 연구의 결과는 다음과 같다. 경관자원조사 및 분석단계는 가장 체계화된 틀로 진행되고 있었으나, 지나치게 세분화되어 실제 경관계획 시 도움이 되지 못하고 있는 부분이 있었다. 반면, 경관구조분석은 경관구조분석에 대한 다양한 접근방법과 기법 등의 구체적 방안 제시가 필요한 것으로 파악되었다. 경관기본구상단계는 기존의 현황조사 결과와 상위계획 등을 반영하여 지역특성에 맞는 지자체 아이엔티티의 확립이 필요하며, 경관계획수립지침에서도 보다 구체적인 지침이 필요한 것으로 파악되었다. 경관기본계획단계는 지자체 간의 수준의 차이가 가장 큰 것으로 나타나서, 경관계획수립지침에서 계획 내용에 대한 구체적인 지침이 필요한 것으로 보인다. 경관계획수립지침 상 경관자원조사 및 분석단계에서는 '경관자원조사 종합 및 과제도출'과 기본경관계획단계의 '조망점 계획'이 추가되는 것이 필요한 것으로 판단된다.

급성 뇌졸중 환자 대상 근거중심 간호 가이드라인 수용개작의 적용 평가 (Evaluation of Applications of Adaptation of the Evidence-Based Nursing Practice Guidelines Patients with Acute Stroke)

  • 송소이;조명숙;김지현;한윤경;양혜민
    • 기본간호학회지
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    • 제19권1호
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    • pp.87-97
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    • 2012
  • Purpose: This study was done to evaluate nursing guidelines for patients with acute stroke, developed by adapting the guidelines of Registered Nurses Association of Ontario, Canada to clinical settings on a large scale and evaluating the effectiveness as a research study. Method: The general characteristics of the 319 patients and the effectiveness of guideline application were evaluated in terms of structure, process, and outcome using questionnaires on the guidelines application with reference to the medical records of patients with acute stroke hospitalized on a ward of the stroke center of S General Hospital in Seoul. Results: Structures as a guidance system for assessment were consistent with the recommendations. With respect to the process of the guidelines, for items on nursing assessment, improved performance was found to be statistically significant. For outcomes of the guidelines, complications occurred in 8 patients (5.3%) prior to application of the guidelines and 11 patients (6.5%) after application of the guidelines, but this result was not statistically significant (p=.841). Conclusion: The results of the study indicate that for the effectiveness of the guidelines, accessibility to the guidelines and effectiveness of quality improvement need to be evaluated, in addition to complications of a stroke.

Land Based Test of Ballast Water Treatment System by Ozonation

  • Park, Sung-Jin;Yoon, Seung-Je;Kim, In-Soo
    • Journal of Advanced Marine Engineering and Technology
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    • 제34권3호
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    • pp.383-390
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    • 2010
  • This study is currently giving priority to developing the ship's ballast water treatment system using ozone (Ozone BWTS). The Ozone BWTS was tested in a full scale land-based mobile barge to evaluate performance according to the IMO G8 Guidelines. Test cycles using the mobile-barge were conducted in seawater and brackish water in the vicinity of the Port of Busan and Nakdong River, Republic of Korea. All tests were conducted according to the requirements of the G8 Guidelines. Test results show that the Ozone BWTS meets the Ballast Water Performance Standard contained in Regulation D-2 of the IMO Ballast Water Management Convention, as well as all of the operational, safety, and environmental testing requirements of the G8 Guidelines, as required for type approval of IMO. The study results show that the Ozone BWTS is capable of meeting the Ballast Water Performance Standard under Regulation D-2 of the International Convention for the Control and Management of Ships’ Ballast Water and Sediments, and also the more stringent standards being proposed under US legislation.

발코니 확장비용 가이드라인에 따른 창호 열성능 분석 (Analysis of Window Thermal Performance according to Guidelines on the Balcony Expansion Costs)

  • 최경석;강재식;이승언
    • 대한설비공학회:학술대회논문집
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    • 대한설비공학회 2008년도 하계학술발표대회 논문집
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    • pp.863-868
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    • 2008
  • In accordance with the guidelines on the balcony structure changes in December 2005, most of tenants were moving into apartment housing, expand the balcony, but some large deviation between the price construction costs set of cases, due to overuse and the cause of the dispute, and the housing law amended in 2007 due to price cap system is implemented, the cost of expansion the balcony overdose pointed out that there is set to boost the sale price has been raised. These issues in order to improve the government in January 2008, the "Note costs by the balcony expansion" suggested guidelines to protect the rights of tenants and wants to promote the settlement of the sale price cap system. This study calculated the "Note costs by the balcony expansion" window system based on double or single, high performance insulation window system of the quantitative performance analysis of each type window that purpose.

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중소기업의 ESG 경영 실천 지표 구성: 자동차부품제조업을 중심으로 (Constructing ESG Management Performance Indicators for Small and Medium-sized Enterprises: Focusing on the Automotive Parts Manufacturing Industry)

  • 방정훈;이운식
    • 산업경영시스템학회지
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    • 제46권3호
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    • pp.89-100
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    • 2023
  • Recently, as ESG management has become an important issue, major companies in the automotive parts manufacturing industry are conducting ESG evaluations of their suppliers for the purpose of supply chain management. The results of these evaluations are being incorporated into contractual agreements. However, many small and medium-sized enterprises(SMEs) are lacking in their capacity and resources to effectively respond to ESG evaluations. Furthermore, existing ESG management guidelines do not provide an industry-specific guidance, making it necessary to establish industry-specific guidelines that SMEs can refer to. Therefore, in this study, the evaluation Indicators of ESG supply chain assessments are surveyed, which is conducted by domestic major automotive parts companies and global automobile manufacturers. Then 56 supply chain ESG evaluation Indicators are derived. Also, ESG management indicators for SMEs is analyzed through the Importance-Performance Analysis(IPA), based on an interview of expert groups. Therefore, this study could propose industry-specific ESG guidelines, based on the results of the derived indicators, which reflects the need for SMEs to practice ESG management within certain boundaries.

도서관 개인정보보호 가이드라인 개발에 관한 연구 (A Study on Developing Guidelines for Personal Information Protection in Library)

  • 노영희;김태경
    • 정보관리학회지
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    • 제32권2호
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    • pp.25-61
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    • 2015
  • 본 연구에서는 도서관 개인정보 가이드라인(안)을 제안하되, 관종을 구분하지 않고 어느 도서관에서나 적용가능하도록 하였다. 개개 도서관은 이 가이드라인(안)을 기초로 하여 자관의 실정에 맞게 수정 보완하여 사용할 수 있도록 하였다. 목적, 용어정의, 개인정보의 범위, 관련법 및 정책, 일반적인 내용, 도서관의 업무수행상 개인정보처리, 도서관의 외주업체 등으로 구분하여 도서관 개인정보보호 가이드라인을 개발하였으며, 개정된 "개인정보 보호법" 시행에 따른 도서관의 대처방향 마련, 개인정보처리지침의 도서관 최적화, 관련법령에의 반영, 도서관 개인정보 가이드라인 표준화 지향 등을 고려하였다.