• Title/Summary/Keyword: Perfect Mixing

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Characterization and Evaluation of Freeze-dried Liposomes Loaded with Ascorbyl Palmitate Enabling Anti-aging Therapy of the Skin

  • Lee, Sang-Kil;Lee, Jae-Hwi;Choi, Young-Wook
    • Bulletin of the Korean Chemical Society
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    • v.28 no.1
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    • pp.99-102
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    • 2007
  • To prepare freeze-dried ascorbyl palmitate (AsP)-containing liposome which can protect the drug from moisture attack and be used instantly by mixing with water for anti-aging and skin whitening therapy, AsP was encapsulated into liposomes and freeze-dried with trehalose. The freeze-dried liposome formulations were characterized by measuring water contents, particle size, time required for complete reconstitution. With the freeze-dried liposomes, we performed the stability test under accelerated conditions, skin permeation and localization test. The measurement of the time to perfect reconstitution showed that the freeze-dried liposomes can be changed to their initial state rapidly and short term stability test of AsP in reconstituted liposomes under accelerated conditions confirmed that the stability of AsP was considerably enhanced as compared to freshly prepared liposomes. The skin permeation and localization properties of AsP in reconstituted liposomes were not significantly different, indicating that the liposomal structures were maintained before and after freezedrying. In conclusion, the freeze-drying method provided a possible way to overcome the instability issue of AsP induced by the moisture and reproduced similar skin permeation and localization properties as shown by freshly prepared liposomes.

Specific Properties and Manufacturing Principle of Low Velocity Explosive Kinecker (저폭속화약 Kinecker의 특성 및 제조 원리)

  • Lee, Ik-Joo;Kim, Hee-Do;Ahn, Bong-Do;Choi, Sung-Hyun;Lim, Jeong-Hyuk
    • Explosives and Blasting
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    • v.24 no.2
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    • pp.23-31
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    • 2006
  • Optimum additive which gets Possible detonation sensitivity and minimum stability has been selected among several additives. It is able to mitigate a chemical reaction without destroying a structure of emulsion. Kinecker has been developed by mixing both matrix and selected additive through a perfect formulation. The detonation pressure is reduced by 40.66%(47.27% by Nitro Dyne's program), and hole pressure by 33.25% and even VOD by 52.88% against currently used emulsion explosives.

Development of Gas Turbine Simulation Program Based on CFD

  • Jin, Sang-Wook;Kim, Jae-Min;Kim, Kui-Soon;Choi, Jeong-Yeol;Ahn, Iee-Ki;Yang, Soo-Seok
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2008.03a
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    • pp.150-156
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    • 2008
  • A program based on a 2-D CFD code has been developed to simulate a gas turbine engine. 2-D Navier-Stokes implicit code with $k-\omega$ turbulent model is used in compressor and turbine. Lumped method chemical equilibrium code with 10 species of molecular is applied to combustor with assuming perfect mixture and 100% combustion efficiency at constant pressure state. Fluid properties are shared on interfaces between engine components. Compressor supplies outlet temperature and pressure to combustor. At the same time, combustor also carries temperature and pressure to turbine. The back pressure of compressor outlet is transferred by inlet pressure of turbine. Unsteady phenomena in rotor-stator are covered by mixing-plane method. The running condition of engine can be determined only by given the inlet condition of compressor, the outlet condition of turbine, equivalence ratio and rotating speed.

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Design and analysis of RIF scheme to improve the CFD efficiency of rod-type PWR core

  • Chen, Guangliang;Qian, Hao;Li, Lei;Yu, Yang;Zhang, Zhijian;Tian, Zhaofei;Li, Xiaochang
    • Nuclear Engineering and Technology
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    • v.53 no.10
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    • pp.3171-3181
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    • 2021
  • This research serves to advance the development of engineering computational fluid dynamics (CFD) computing efficiency for the analysis of pressurized water reactor (PWR) core using rod-type fuel assemblies with mixing vanes (one kind of typical PWR core). In this research, a CFD scheme based on the reconstruction of the initial fine flow field (RIF CFD scheme) is proposed and analyzed. The RIF scheme is based on the quantitative regulation of flow velocities in the rod-type PWR core and the principle that the CFD computing efficiency can be improved greatly by a perfect initialization. In this paper, it is discovered that the RIF scheme can significantly improve the computing efficiency of the CFD computation for the rod-type PWR core. Furthermore, the RIF scheme also can reduce the computing resources needed for effective data storage of the large fluid domain in a rod-type PWR core. Moreover, a flow-ranking RIF CFD scheme is also designed based on the ranking of the flow rate, which enhances the utilization of the flow field with a closed flow rate to reconstruct the fine flow field. The flow-ranking RIF CFD scheme also proved to be very effective in improving the CFD efficiency for the rod-type PWR core.

Thermal post-buckling analysis of graphene platelets reinforced metal foams beams with initial geometric imperfection

  • Gui-Lin She;Yin-Ping Li;Yujie He;Jin-Peng Song
    • Computers and Concrete
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    • v.33 no.3
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    • pp.241-250
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    • 2024
  • This article investigates the thermal and post-buckling problems of graphene platelets reinforced metal foams (GPLRMF) beams with initial geometric imperfection. Three distribution forms of graphene platelet (GPLs) and foam are employed. This article utilizes the mixing law Halpin Tsai model to estimate the physical parameters of materials. Considering three different boundary conditions, we used the Euler beam theory to establish the governing equations. Afterwards, the Galerkin method is applied to discretize these equations. The correctness of this article is verified through data analysis and comparison with the existing articles. The influences of geometric imperfection, GPL distribution modes, boundary conditions, GPLs weight fraction, foam distribution pattern and foam coefficient on thermal post-buckling are analyzed. The results indicate that, perfect GPLRMF beams do not undergo bifurcation buckling before reaching a certain temperature, and the critical buckling temperature is the highest when both ends are fixed. At the same time, the structural stiffness of the beam under the GPL-A model is the highest, and the buckling response of the beam under the Foam-II mode is the lowest, and the presence of GPLs can effectively improve the buckling strength.

Effect of Head Rice Ratio on Rice Palatability (쌀의 완전미 비율 증가가 식미에 미치는 영향)

  • Chung Nam-Jin;Park Jeong-Hwa;Kim Kee-Jong;Kim Je-Kyu
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.50 no.spc1
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    • pp.29-32
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    • 2005
  • This experiment aimed to estimate the effect of imperfect rice on rice palatability. Rice cultivar, Ilpumbyeo, was cultivated by direct-seeding on flooded paddy surface with 11 kg/10a nitrogen application. Palatability of harvested rice was measured by NIR spectroscope. Brown rice was divided according to their appearance namely, perfect, discolored, green-kerneled, and immature opaque with a composition ratio of $75.7\%,\;11.0\%,\;8.0\%,\;and\;5.3\%$ respectively. When the perfect brown rice was milled, the grain were composed of head, cracked, and white core & belly, at $64.7\%,\;25.3\%\;and\;10.0\%$ respectively. The milled rice of discolored brown rice had similar composition with the perfect rice. The milled green-kerneled vice, on the other hand, had $36\%$ head rice and $64\%$ white core & belly rice. The immature opaque brown rice, when milled, had $25.3\%$ white core & belly and $74.7\%$ damage & opaque rice. With the respect to grain quality, the viscosity of white core at belly rice and damaged & opaque rice was lower than that of head rice. In contrast, their protein content was a little higher than that of head rice. The palatability value of pure imperfect rice was much lower than head rice. The palatability value of damaged & opaque rice was the lowest among the imperfect rices. When mixed with head rice, the damaged & opaque rice impacted on the deterioration of vice palatability. Mixing $1\%$ each of white core at belly rice and damaged h opaque rice decreased the palatability value by $5\%$ as compared with the head rice.

Transparency of various silk fibroin membranes (혼합 실크 피브로인막의 투명도)

  • Jo, You-Young;Kweon, HaeYong;Yeo, Joo-Hong;Lee, Kwang-Gill
    • Journal of Sericultural and Entomological Science
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    • v.51 no.2
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    • pp.197-200
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    • 2013
  • Silk fibroin is a natural biomaterial that has the biocompatibility and other many advantages. But as a silk fibroin membrane thickness increases, the transparency becomes more opaque. Because the transparency of membranes tissue such as the cornea and dura mater are necessary, transparent membrane is required to replace these transparent membranes. In this study, we fabricated blending silk fibroin membranes that made by mixing the various inorganic salts or polymer in an aqueous solution of silk fibroin. The transparency of the membranes were analyzed. the transparency of these membranes is very different, depending on the mixed materials. Inorganic salts mixed silk membrane was more transparent than the polymer mixed one. Especially, the silk fibroin membrane with calcium chloride was very transparent. We showed the possibility of blending silk fibroin membrane, which can be used in perfect transparent membrane such as the cornea. In the future, we expect that the transparent blending silk fibroin membrane can be used in various medical applications.

Effects of Two-dimensional Heat and Mass Transports on Condensational Growth of Soot Particles in a Tubular Coater (원형관 코팅장치에서 연소 입자의 응축성장에 미치는 2차원 열 및 물질전달의 영향)

  • Park, Sung Hoon
    • Particle and aerosol research
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    • v.9 no.3
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    • pp.163-171
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    • 2013
  • Soot particles emitted from combustion processes are often coated by non-absorbing organic materials, which enhance the global warming effect of soot particles. It is of importance to study the condensation characteristics of soot particles experimentally and theoretically to reduce the uncertainty of the climate impact of soot particles. In this study, the condensational growth of soot particles in a tubular coater was modeled by a one-dimensional (1D) plug flow model and a two-dimensional (2D) laminar flow model. The effects of 2D heat and mass transports on the predicted particle growth were investigated. The temperature and coating material vapor concentration distributions in radial direction, which the 1D model could not accounted for, affected substantially the particle growth in the coater. Under the simulated conditions, the differences between the temperatures and vapor concentrations near the wall and at the tube center were large. The neglect of these variations by the 1D model resulted in a large error in modeling the mass transfer and aerosol dynamics occurring in the coater. The 1D model predicted the average temperature and vapor concentration quite accurately but overestimated the average diameter of the growing particles considerably. At the outermost grid, at which condensation begins earliest due to the lowest temperature and saturation vapor concentration, condensing vapor was exhausted rapidly because of the competition between condensations on the wall and on the particle surface, decreasing the growth rate. At the center of the tube, on the other hand, the growth rate was low due to high temperature and saturation vapor concentration. The effects of Brownian diffusion and thermophoresis were not high enough to transport the coating material vapor quickly from the tube center to the wall. The 1D model based on perfect radial mixing could not take into account this phenomenon, resulting in a much higher growth rate than what the 2D model predicted. The result of this study indicates that contrary to a previous report for a thermodenuder, 2D heat and mass transports must be taken into account to model accurately the condensational particle growth in a coater.

Papers : A Study on the Characteristics of the Ramjet Engine Combustor using a Two Color PIV Technique (논문 : Two Color PIV 기법을 이용한 램제트엔진 연소기 특성에 대한 연구)

  • An,Gyu-Bok;Yun,Yeong-Bin;Jeong,In-Seok;Heo,Hwan-Il
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.30 no.1
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    • pp.95-104
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    • 2002
  • A two color PIV technique has been developed for visualization of complex and high speed flow in a ramjet combustor. Two color PIV has the advantages that velocity distribytions in high speed flowfields can be measured simply by varying the time interval between two different laser beams and a directional ambiguity problem can be solved by color separation, and then a singnal-to-noise ratio can be increased through nearly perfect cross-correlation. As a basic research of the ramjet engine, a 2-D shaped combustor with two symmetric air intakes has been manufactured and an experimental study has been conducted using a two color PIV technique. The flow characteristics such as recirculation zones and two intake air mixing have been investigated varying inlet angles and dome heights. It is found that the size and air mass ratio of reciculation zones are affected mainly by an inlet angle, but not much by a dome height.

Hydrodynamics and Liquid Flow Characteristics in an Internal Circulation Airlift Reactor using a Single Nozzle (단일노즐을 사용한 내부순환 공기리프트 반응기에서 수력학과 액체의 흐름특성)

  • Kim, Jong-Chul;Jang, Sea-Il;Son, Min-Il;Kim, Tae-Ok
    • Applied Chemistry for Engineering
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    • v.8 no.5
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    • pp.816-821
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    • 1997
  • The hydrodynamics and the liquid flow characteristics were investigated in an internal circulation airlift reactor with a single nozzle as a gas distributor. In an air-water system, the gas holdup in the individual flow zone and the impulse-response curve of tracer were measured at various gas velocities and reactor heights. Experimental results showed that for the higher gas velocity(>about 8 cm/s), the flow behavior of bubbles in the riser was turbulent flow due to strong bubble coalescences and the axial height of dispersion zone of large bubbles having uniform sizes in the downcomer was decreased with increasing gas velocity. And mean gas holdups in the individual flow zone and the reactor were increased with increasing gas velocities and were decreased with increasing heights of the top section of the reactor and it was decreased with increasing the height of the top section and gas velocity. Flow characteristics of liquid in the riser and the downcomer was tend to access to plug flow and the overall flow behavior of liquid was mainly varied with the size of the top section which it was assumed to be perfect mixing zone. In these conditions, liquid circulation velocities were increased with increasing gas velocities and they were higher than those by using other gas distributors.

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