• Journal of Magnetics
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• 제4권3호
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• pp.76-79
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• 1999

We report results on metastable CuCo ribbons at low Co contents (2 and 10 at %), which were prepared by conventional melt-spinning technique and subsequent annealing. The properties of these materials cannot consistently be described by those of an assembly of superparamagnetic single-domain particles. Magnetic measurements related to magnetic dynamics reveal spin-glass-like properties. Especially, we find very slow nonequilibrium relaxation processes in Co10Cu90, which depend on prehistory, when probing the relaxation of the resistivity. The results are clear evidence for frustrated interaction effects due to magnetic couplings between Co clusters or precipitates in these alloys.

• BMB Reports
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• 제47권9호
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• pp.500-505
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• 2014

Colorectal cancer has become the third most common cancer and leads to high mortality worldwide. Although colorectal cancer has been studied widely, the underlying molecular mechanism remains unclear. PER3 is related to tumor differentiation and the progression of colorectal cancer. High expression of miR-103 is associated with poor prognosis in patients with colorectal cancer. However, the relationship between miR-103 and PER3 in CRC cells remains unclear. In this study, we found that PER3 was downregulated in CRC tissues and CRC cell lines, whereas miR-103 was upregulated in CRC cell lines. We also found that PER3 promoted CRC cells apoptosis. These results indicate that PER3 plays a suppressive role in CRC cells. Moreover, we found that PER3 was targeted, at least partially, by miR-103. Taken together, we provide evidence to characterize the role of PER3 in CRC, which may be a new therapeutic target for CRC.

• 한국균학회지
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• 제37권1호
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• pp.19-27
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• 2009

25개의 큰느타리버섯 균주를 국내외의 다양한 지역에서 수집하여 본 실험에 사용하였다. PER-007과 PER-012균주는 다른 균주와 비교하여 볼 때 PDA 배지상에서 특징적인 균총 형태를 보였으나 대부분 균주간 유사한 균사생장률을 보였다. 자실체 유도 및 생육 실험에서 PER-007균주는 자실체가 형성 되지 않았고 PER-012균주의 발이가 되었으나 이후 성숙 자실체로 성장하지 않았으며 그 외의 공시한 균주의 자실체 대부분의 갓모양은 볼록반구형, 평판구형 등 다양하게 나타났다. URP primer의 PCR 반응 조건은 $48^{\circ}C$에서 $52^{\circ}C$의 annealing 온도에서 높은 다형성 밴드를 관찰할 수 있었으며 25개의 P. eringii strains의 다형성은 11개의 URP primer 중 URP1F, URP2R, URP2F, URP4R, URP6R, URP9F, URP17R primer에서 계통간 PCR 다형성 밴드를 형성하였다. URP-PCR다형성밴드를 기초로 하여 유전적 유연관계를 분석한 결과 P. eringii strain들은 $76%{\sim}100%$정도의 유전적 유사도를 가지는 3개의 주요 group으로 나눌 수 있었으며 PER-007과 PER-017균주는 outgroup으로 원연관계를 형성하였다.

• Asian-Australasian Journal of Animal Sciences
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• 제13권12호
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• pp.1717-1725
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• 2000

The objective was to determine the relationship between feed intake levels and patterns, and growth performance and body composition of barrows and gilts using automatic feed intake recording equipment (F.I.R.E.). This system records the time of visits to the feeder and the duration and size of meals for individual animals housed in groups. Ninety-six crossbred pigs were grown from $33.4{\pm}0.51$ to $109.7{\pm}1.39kg$ live weight over a 13-week period. Eight mixed-sex groups of 12 pigs were used and 4 dietary treatments were compared giving 2 pens per treatment. The dietary treatments consisted of corn-soybean meal diets with differing protein levels which ranged from 14.7% to 19% between 30 to 55 kg, from 13.3% to 16.9% between 56 and 85 kg, and from 12.3% to 16.8% for the remainder of the study. Animals were ultrasonically scanned to measure loin-eye area and backfat thickness to estimate carcass fat-free lean content at the beginning and end of the study. Barrows had higher daily feed intake than gilts (2.67 vs. 2.46 kg resp. p<0.05) which was the result of a longer feeder occupation time per visit (4.77 vs. 4.54 min, resp. p<0.05), higher feed consumption rates (30.4 vs. 29.0 g/min, resp. p<0.05), and higher feed intakes per visit (136.9 vs. 126.8 g, resp. p<0.01). Gilts had less backfat and greater loin-eye area than barrows (p<0.05). Diet had no significant effect on growth performance and had limited impact on feeding patterns. Body weight showed high correlations with ADG (r=0.74), feed intake per visit (r=0.51) and feed consumption rate (r=0.69). Positive correlation were also found between daily feed intake and feed intake per visit (r=0.45), feeder occupation time per day (r=0.56), and feed consumption rate (r=0.55), and between daily feed intake and backfat thickness (r=0.32) and feed consumption rate and loin-eye area (r=0.32). There were negative correlations between number of feeder visit per day and daily feed intake (r=-0.54), and between feed intake per visit and number of feeder visits per day (r=-0.43). However, correlations between feed intake traits and carcass traits were generally low. Visits to the feeder were greatest during the morning (0700 to 1100 h) and lowest during the evening and nighttime. These results highlight limited variation among the sexes in feeding patterns and suggest important relationships between feeding behavior and feed intake.

• 기본간호학회지
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• 제8권1호
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• pp.51-68
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• 2001

The purpose of this study was to explain the relationship between smoking status, smoking behavior and hardiness in university students in Gangnung City. The subjects were a convenience sample of 315 students. The data were collected by a questionnaire given to the students between May 22 to June 2, 2000. An instrument developed by Akers & Gang(1996) and translated by Sohn, Jung-Nam(1999) was used in this study to measure definition of smoking, differential reinforcement of smoking and smoking behavior. The differential peer association scale developed Krohn et al.(1982) and translated by Sohn, Jung-Nam(1999), and the hardiness scale developed by Pollock(1984) and translated by Suh, Mun-Sa(1988) were also used. The data were analyzed using the SAS/PC+ Program and included descriptive statistics, t-test, ANOVA, and Spearman correlation coefficients. The results of this study are as follows : 1. The smoking rate for university students was 50.5% of which 44.7% started smoking in high school. 2. The mean score for level of hardiness was $3.14{\pm}0.43$ 3. The mean score for smoking behavior was as follows : 1) The mean score for the neutralizing definition was $2.16{\pm}0.57$ 2) The mean score for the negative definition was $2.37{\pm}0.71$ 3) The mean score for the positive differential reinforcement was $1.89{\pm}0.63$ 4) The mean score for the negative differential reinforcement was $2.96{\pm}0.64$ 5) The mean score for the differential peer association was $2.67{\pm}1.05$ 4. The data showed positive correlations between hardiness and the neutralizing definition(r=.1951, P<.001), between hardiness and the positive differential reinforcement(r=.1128, P<.05), between hardiness and the amount of smoking per day(r=.1452, P<.05) between the neutralizing definition and positive differential reinforcement(r=.4212, P<.0001), between the neutralizing definition and differential peer association(r=.1856, P<.001), between the neutralizing definition and age at smoking initiation(r=.1582, P<.05), between the negative definition and negative differential reinforcement(r=.2985, P<.0001), between the positive differential reinforcement and differential peer association(r=.3451, P<.0001), between positive differential reinforcement and the amount of smoking per day(r=.4431, P<.0001), between differential peer association and the duration of smoking(r=.2789, P<.0001), between differential peer association and the amount of smoking per day(r=.5410, P<.0001), between the duration of smoking and the amount of smoking per day(r=.4245, P<.0001). The data showed negative correlations between the neutralizing definition and the negative definition(r=-.2065, P<.001) between the neutralizing definition and negative differential reinforcement(r=-.3943, P<.0001) between the neutralizing definition and duration of smoking(r=-.1957, P<.05), between the negative definition and positive differential reinforcement(r=-.2093, P<.001), between the negative definition and the amount of smoking per day(r=-.2282, P<.001), between positive differential reinforcement and negative differential reinforcement(r=-.5555, P<.0001) between negative differential reinforcement and differential peer association(r=-.3653, P<.0001), between negative differential reinforcement and the amount of smoking per day(r=-.4570, P<.0001), between the age at smoking initiation and the duration of smoking(r=-.4594, P<.0001).

• 자연과학논문집
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• 제18권1호
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• pp.47-53
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• 2007

바실러스 서브틸리스 유전체에서 여러 환경의 적응에 이용할 것으로 보이는 새로운 small RNA를 찾는 시도로 다음과 같은 방식으로 유전체를 검색하였다. 첫째로 유전자들 사이에 존재하는 DNA 서열을 대상으로 전사인자들인 PerR, OhrR, Fur, Zur의 인식서열을 조사하였고, 둘째로 인자 비의존성 전사종결 부위를 조사하였다. 이들 조사에서 전사인자의 위치와 전사종결부위가 300 bp 내외에서 가까이 존재하는 후보 DNA 서열을 대상으로 전사인자 부위에서 전사촉진자의 서열이 발견되는지를 조사하였다. 이 결과 PerR 5개, Fur 2개, OhrR, Zur에서 각각 1개의 새로운 small RNA로 추정되는 부위가 발견되었다.

• 자원ㆍ환경경제연구
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• 제25권1호
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• pp.89-112
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• 2016

본 논문은 환경쿠즈네츠곡선가설에 기반을 두고, 경제개발 수준과 기술혁신수준이 다른 전세계 88개 국가에 대한 패널데이터를 이용하여, 기술혁신이 이산화탄소배출량 변화에 미치는 영향을 분석하였다. 기술혁신이 온실가스배출량에 직접적으로 미치는 효과와 소득수준을 변화시켜 온실가스배출량에 미치는 간접적 효과를 종합해본 결과, 비록 미세하지만 기술혁신은 결과적으로 온실가스배출량을 증가시키는 것으로 나타났다. 그러나 패널데이터 모형은 각 '시점 내'에서 변수 간 효과를 분석하는 정태적 모형이라는 한계를 가지고 있다. 이를 개선하기 위해 본 논문에서 채용한 Panel VAR(Panel Vector Auto Regression)모형에서는 기술혁신수준이 시차를 두고 온실가스 배출량에 미치는 영향을 분석할 수 있다. 분석 결과 기술혁신(R&D 투자)과 같은 외생적 충격(Shock)이 일인당 온실가스 배출량 감축에 3년 정도의 시차를 두고 영향을 미치는 것으로 나타났다.

• 산업공학
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• 제5권1호
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• pp.61-74
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• 1992

Recognizing the lack of empirical studies on the returns to R & D investment in Korean firms, this paper analyzes the relationships between R & D investment and corporate performances measured by sales growth rate, profit rate and PER. The data used here are from 167 firms in 8 different industries covering the period from 1985 to 1989. The results show that the profit rate is strongly correlated with R & D investment. But unlike the results of most studies previously done in the U.S., R & D investment only weakly and insignificantly correlated with sales growth and PER.

• 한국작물학회지
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• 제14권
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• pp.41-45
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• 1973

본 시험은 중부지방에서 담수직파재배에 알맞은 파종립수를 구명함과 파종립수에 EK른 수량 및 수량구성요소의 변이를 알고져 1972년에 수행하였던 바 그 결과를 요약하면 다음과 같다. 1. 최고분얼수는 밀파할수록 직선적으로 증가하여 280립 파종구에서 최고수치를 보였고 그 이후는 점차 감소되었으며 분얼에 대한 경합은 $m_2$당 280립이상 파종구에서 뚜렸했다. 2. 유효경비율은 $m_2$당 120립부터 280립 파종구까지는 파종밀도가 증가될수록 감소되다가 그 이후는 점차 증가되었다. 3. 최고분얼수가 $m_2$당 1,000개 이하에서는 얼자간 경합이 적었다. 4. 수수와 파종립수는 현저한정(+)의 상관이 인정되었고 수수와 일수영화수, 수수와 동숙비율은 (-)의 상관 경향이었다. 5. 수량과 $m_2$당 영화수는 r=0.929이며 수량과 수수는 r=0.695, 수수와 $m_2$당 영화수는 r=0.796이었다. 또한 수량과 수량구성요소간의 순위상관을 보면 수량과 수수가 가장 상관이 높았으며 (r=0.954_ 담수직파에서 수량을 지배하는 요인은 수수이었다. 6. 수량은 $m_2$당 280립 파종구에서 최고를 나타냈다.

• Bulletin of the Korean Chemical Society
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• 제31권6호
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• pp.1573-1576
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• 2010

Bacillus subtilis PerR is a metal-dependent peroxide-sensing transcription factor which uses metal-catalyzed histidine oxidation for peroxide-sensing. PerR contains two metal binding sites, one for structural $Zn^{2+}$ and the other for the regulatory/peroxide-sensing metal. Here we investigated the effect of mutations at both the structural and regulatory metal binding sites on the oxidation of either H37 or H91, two of the peroxide-sensing ligands. All four serine substitution mutants at the structural $Zn^{2+}$ site (C96S, C99S, C136S and C139S) exhibited no detectable oxidation at histidine residues. Two of the alanine substitution mutants at regulatory metal site (H37A and D85A) exhibited selective oxidation preferentially at the H91-containing tryptic peptide, whereas no oxidation was detected in the other mutants (H91A, H93A and D104A). Our results suggest that the cysteine residues coordinating structural $Zn^{2+}$ are essential for peroxide sensing by PerR, and that the C-terminal regulatory metal binding site composed of H91, H93 and D104 can bind $Fe^{2+}$, providing a possible explanation for the peroxide sensing mechanisms by PerR.