• Journal of Chest Surgery
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• v.33 no.8
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• pp.648-654
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• 2000

Background: Cardiopulmonary bypass during open heart surgery causes systemic inflammatory respose. IL-10 is an anti-inflammatory cytokine that inhibits inflammatory process and protects organ function by down regulation of pro-inflammatory cytokine release and maintenance of blood level balance with pro-inflammatory cytokines. Mateial and Method: Plasma IL-10 levels were measured and analyzed in 22 patients who underwent open heart surgery (11 cases of coronary artery bypass graft, 11 cases of valve replacement) under cardiopulmonary bypass since 1988 January to July at Department of Thoracic and Czardiovascular surgery, Yeungnam University Hospital. 1g of methylprednisolone was administrated to thirteen patients randomly. Blood samp.es were taken and collected at the time of induction of anesthesia, 10 min before cardiopulmonary bypass, 10 min after starting of CPB, 10 min aftr aortic cross clamping, 10 min after ACC release, and 10 min, 2 hours, and `5 hours after CPB respectively. The plasma levels of IL-10 were determined by enzyme-linked immunosorbent assays(ELISA). Wilcoxon-Raule Sum test was used for statistical analysis. Result: In all 22 patients, cardiopulmonary bypass time was used for statistical analysis. Result: In all 22 patients, cardiopulmonary bypass time was 171$\pm$41.4 min and aortic cross clamp time was 118$\pm$36.5 min. Peak IL-10 level was achieved at 10 min after ACC(361.0$\pm$52.81pg/ml) and was decreased sharply at 2 hours after CPB. Peak IL-10 level was correlated positively with aortic cross clamp time(p=0.011); however, it did not correlated with bypass time(p=0.181). In valve replacement group, mean IL-10 level at peak point was 567.89$\pm$107.69 pg/ml and was significantly higher than that of coronary artery bypass group(205.67$\pm$192.70 pg/ml)(p<0.001). ACC time in valve replacement group was significantly longer than that of coronary artery bypass group(p<0.01), however, bypass time was not(p=0.212). Thirteen patients with steroid pretreatment before starting of CPB showed relatively higher plasma IL-10 level than in control group, however, no statistical significance was noted(p=0.19). Conclusion: plasma level of IL-10 was increased in association with cardiopulmonary bypass and revealed peak at 10 min after ACC release. IL-10 level was correlated positively with ACC time. Therefore, systemic inflammatory respeonse in association with cardiopulmonary bypass could be decreased by reducing ACC time during cardiac surgery.

• Structural Engineering and Mechanics
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• v.5 no.2
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• pp.149-165
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• 1997

A dynamic time-history analysis of the coupled internals and core in the vertical direction is performed as a part of the fuel assembly qualification program. To reflect the interaction between the fuel rods and grid cage, friction element is developed and is implemented. Also derived here is a method to calculate a hydraulic force on the reactor internals due to pipe break. Peak responses are obtained for the excitations induced from earthquake and pipe break. The dynamic responses such as fuel assembly axial forces and lift-off characteristics are investigated.

• The Transactions of the Korean Institute of Electrical Engineers C
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• v.48 no.10
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• pp.687-692
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• 1999

A new technique to measure low level capacitance variations of the gyroscope is proposed and verified by computer simulation. It is based on the new CV(capacitance-voltage) converter circuit biased by dc current source and the peak detector without low pass filter. The CV converter biased by dc current source provides good signal-to-noise ratio and this setup of the detection circuitry without low pass filter makes it possible to provide short settling time, that is, higher speed of measurement and wide operation range if only a few parameters are adjusted. The key parameters that affect the performance of the detection circuitry are illustrated and computer simulation results are presented. The demonstrated detection circuitry shows linear response from 10 fF to 130 fF at 10 kHz and shows good linearity.

• Bulletin of the Korean Chemical Society
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• v.28 no.10
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• pp.1720-1724
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• 2007

Electrochemical behaviors of bovine hemoglobin (Hb) at an acetylene black paste electrode based on the enhancement effect of sodium dodecyl sulfate (SDS) were investigated. In the optimal conditions, a very weak reduction peak was observed at an acetylene black paste electrode for hemoglobin in the absence of SDS. However, the reduction peak current increased remarkably after the addition of 4.0 × 10?4 mol L?1 SDS, suggesting that SDS exhibits obvious enhancement effect to the determination of hemoglobin. All the experimental parameters, such as pH value, concentration of SDS, accumulation time and accumulation potential were optimized for hemoglobin analysis. The proposed method possesses high sensitivity (detection limit is 3.0 × 10?9 mol L?1), wide linearity (6.0 × 10?9 to 6.0 × 10?7 mol L?1), rapid response and low cost. Finally, the method was successfully employed to determine hemoglobin in a spiked sample.

• Journal of the Korean Society for Heat Treatment
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• v.24 no.4
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• pp.193-198
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• 2011

Effect of CaO addition on age hardening response has been studied by using optical microscopy, scanning electron microscopy and differential thermal analysis in AZ91 and CaO-containing ECO-AZ91 alloys. After solution treatment, the ${\beta}$($Mg_{17}Al_{12}$) phase formed during solidification mostly disappeared in the microstructure in the AZ91 alloy, whereas numerous ${\beta}$ precipitates containing Ca were still observed in the ECO-AZ91 alloy due to its enhanced thermal stability. The ECO-AZ91 alloy showed the delayed peak aging time and higher peak hardness compared with those of the AZ91 alloy. The activation energies for ${\beta}$ precipitation calculated by means of Kissinger method increased from 71.4 to 85.6 kJ/mole by the addition of CaO, which implies that CaO plays a role in reducing ${\beta}$ precipitation rate in the AZ91 alloy.

• International Journal of Naval Architecture and Ocean Engineering
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• v.6 no.4
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• pp.1148-1159
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• 2014

Different procedures for estimation of the extreme global wave hydroelastic responses in ships are discussed. Firstly, stochastic procedures for application in detailed numerical studies (CFD) are outlined. The use of the First Order Reliability Method (FORM) to generate critical wave episodes of short duration, less than 1 minute, with prescribed probability content is discussed for use in extreme response predictions including hydroelastic behaviour and slamming load events. The possibility of combining FORM results with Monte Carlo simulations is discussed for faster but still very accurate estimation of extreme responses. Secondly, stochastic procedures using measured time series of responses as input are considered. The Peak-over-Threshold procedure and the Weibull fitting are applied and discussed for the extreme value predictions including possible corrections for clustering effects.

• Proceedings of the KIEE Conference
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• 1993.07a
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• pp.316-318
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• 1993

In order to estimation the optimum PID parameter of the turbine speed controller, the response cure of the object plant was compared with the reference pattern and then the magnitude peak value error and peak time error was calculated. With the calculated errors as input into the Fuzzy inference Method was introduced to propose the tuning method for each parameter. And the computer simulation was performed with the above Fuzzy inference method in which the Chunju hydro power plant turbine governor system was used as a model. This Study also aims to develop the exclusive tuner for govenor using industrial computer.

• Journal of the Earthquake Engineering Society of Korea
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• v.15 no.5
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• pp.35-44
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• 2011

PGA (Peak Ground Acceleration) is the parameter which indicates the peak value for strong ground motion and is mainly due to the intensity of the seismic wave. Usually, seismic waves can consist of different characteristics and can have different effects on structures. Therefore, it may be undesirable that the effects of a seismic wave are evaluated only based on the PGA. In this study, time history analysis was executed with a single degree of freedom model for inelastic seismic analysis. The numerical model was assumed to be a perfect elasto-plastic model. Input accelerations were made with El Centro NS (1940), other earthquake records and artificial earthquakes. The displacement ductility demand and cumulative dissipated energy, which were calculated from other artificial earthquakes, were compared. As a result, different responses from other seismic waves which have the same PGA were identified. Therefore, an index which could reflect both seismic and structural characteristics is needed. The SI (Spectrum Intensity) scale which could be obtained from integration by parts of the velocity response spectrum could be an index reflecting the inelastic seismic response of structures. It can be possible to identify from correlation analysis among the SI scale, displacement ductility demand and cumulative dissipated energy that the SI scale is sufficient to be an index for the inelastic response of structures under seismic conditions.

• Geomechanics and Engineering
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• v.24 no.2
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• pp.193-203
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• 2021

The time-history finite element analysis is usually used to evaluate the seismic response of shallow foundations. However, the literature lacks studies on the influence of the soil constitutive model complexity on the seismic response of shallow foundations. This study, thus, aims to fill this gap by investigating the seismic response of shallow foundation resting on dry silica sand using the linear elastic (LE) model, elastic-perfectly-plastic (EPP) model, and hardening soil with small strain stiffness (HS small) model. These models have been used because it is intended to compare the results of a soil constitutive model that accurately captures the seismic response of the soil-structure interaction problems (which is the HS small model) with simpler models (the LE and EPP models) that are routinely used by practitioners in geotechnical designs. The results showed that the LE model produces a very small seismic settlement value which is approximately equal to zero. The EPP model predicts a seismic settlement higher than that produced using the HS small model for earthquakes with a peak ground acceleration (PGA) lower than 0.25 g for a relative density of 45% and 0.40 g for a relative density of 70%. However, the HS small model predicts a seismic settlement higher than the EPP model beyond the aforementioned PGA values with the difference between both models increases as the PGA rises. The results also showed that the LE and EPP models predict similar trend and magnitude of the acceleration-time relationship directly below the foundation, which was different than that predicted using the HS small model. The results reported in this paper provide a useful benchmark for future numerical studies on the response of shallow foundations subjected to seismic shake.

• Journal of Biosystems Engineering
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• v.33 no.5
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• pp.348-354
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• 2008

Egg grading is determined by exterior and interior quality. Among the evaluation methods for the egg quality, a candling method is common to identify eggs with cracked shells and interior defects. But this method is time-consuming and laborious. In addition, practically, it is challenging to detect hairline and micro cracks. In this study, an on-line inspection system based on acoustic resonance frequency analysis was developed to detect hairline cracks on eggshells. A roller conveyor was used to transfer eggs along one lane to the impact position where each of eggs rotated by the roller was excited with an impact device at four different locations on the eggshell equator. The impact device was consisted of a plastic hammer and a rotary solenoid. The acoustic response of the egg to the impact was measured with a small condenser microphone at the same position as the impact device was installed. Two acoustic parameters, correlation coefficient for normalized power spectra and standard deviation of peak resonant frequencies, were used to detect cracked eggs. Intact eggs showed relatively high correlations among the four normalized power spectra and low standard deviations of the four peak resonant frequencies. On the other hand, cracked eggs showed low correlations and high standard deviations as compared to the intact. This method allowed a crack detection rate of 97.6%.