• Title/Summary/Keyword: Peak period

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Two Treatment Cases of Combined Korean Medicine for Patients with Dermatological Diseases Exacerbated by COVID-19 (COVID-19로 악화된 피부과 질환 환자의 한의 치료 2례에 대한 증례보고)

  • Kwan Hee, Lee;Jung Min, Yoo;Hyung Bin, Yoo;Dong Lim, Ha;Hye In, Jeong;Hong Jun, Kim;Kyeong Han, Kim
    • Herbal Formula Science
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    • v.30 no.4
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    • pp.351-361
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    • 2022
  • Objectives : The purpose of this study is to report the clinical effect of herbal medicine decoction on COVID-19 symptoms remaining after administering Western medicine and worsening eczema during the COVID-19 prevalence period in patients with chronic eczema. Methods : The two chronic eczema patients suffering from COVID-19 symptoms and worsening eczema received a series of herbal medicine decoction for treatment. The effectiveness of treatment was evaluated by VAS, NRS, EASI, PASI, DLQI, photography and subjective evaluation of the patient's improvement of symptoms. Results : After treatment, all symptoms of COVID-19 disappered and aggravated eczema lesions were remarkably improved in both cases. Compared to its peak, the first case shows that PASI improved by 88% and DLQI by 44%. According to photo and symptom changes, the size of the affected area of facial acne and lip eczema was decreased. The second case shows that EASI improved by 43% and DLQI by 65%. According to photo and symptom changes, redness, rash were stopped and pruritus was decreased. Conclusion : This study suggests that herbal medicine could induce effectiveness on both COVID-19 symptoms as well as chronic eczema.

Performance, hemato-biochemical indices and oxidative stress markers of broiler chicken fed phytogenic during heat stress condition

  • Olatunji Abubakar, Jimoh;Olajumoke Temidayo, Daramola;Hafsat Ololade, Okin-Aminu;Olayinka Abosede, Ojo
    • Journal of Animal Science and Technology
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    • v.64 no.5
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    • pp.970-984
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    • 2022
  • Thermal stress is a tremendous health predicament encountered by poultry farmers with adverse effects on the performance, product stature, health condition, survival, and overall welfare of poultry birds, and so requires urgent dietary user-friendly strategy to curb. This study was conducted with 200-day old broilers for the purpose of investigating the potential of phytogenics in refining the negative effects of heat stress on broiler chicken. Moringa, Phyllanthus and mistletoe leaves were processed as phytogenic supplements and incorporated into standard ration for broilers as treatments B1 (control), B2, B3 and B4 diet during the peak of thermal discomfort in humid tropics. Growth and carcass indices were monitored in a 49-day trial and blood samples were harvested at the end of the ordeal period to assess haematology, serum biochemical and oxidative stress markers with the use of standard procedures. The results obtained showed that the prevailing environmental condition in the study site indicated that the birds were exposed to heat stress. Birds fed on moringa and mistletoe supplements had higher performance index than birds without supplementation during heat stress condition, while birds fed on mistletoe supplement had the highest survival rate across the treatments. The liveweight, slaughter weight, dressed weight and eviscerated weight of heat stressed birds fed on moringa, phyllanthus and mistletoe supplements were significantly higher than birds on control treatment. Heterophyl/lymphocyte ratio of heat stressed birds without supplement were higher than birds on phytogenic supplements, with least values recorded in phyllanthus and mistletoe fed birds. Birds on phytogenic supplement tend to have lower cholesterol profile, lipid peroxidation and better antioxidant profile than birds on control treatment during heat stress conditions. Mistletoe supplementation in broiler ration enhances the survival rate, as well as promotes growth indices better among the phytogenic supplements. However, phytogenic supplements did ameliorate the negative effects of thermal discomfort on performance, physiological and oxidative stress in heat-stressed broiler chicken.

Real-time prediction for multi-wave COVID-19 outbreaks

  • Zuhairohab, Faihatuz;Rosadi, Dedi
    • Communications for Statistical Applications and Methods
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    • v.29 no.5
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    • pp.499-512
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    • 2022
  • Intervention measures have been implemented worldwide to reduce the spread of the COVID-19 outbreak. The COVID-19 outbreak has occured in several waves of infection, so this paper is divided into three groups, namely those countries who have passed the pandemic period, those countries who are still experiencing a single-wave pandemic, and those countries who are experiencing a multi-wave pandemic. The purpose of this study is to develop a multi-wave Richards model with several changepoint detection methods so as to obtain more accurate prediction results, especially for the multi-wave case. We investigated epidemiological trends in different countries from January 2020 to October 2021 to determine the temporal changes during the epidemic with respect to the intervention strategy used. In this article, we adjust the daily cumulative epidemiological data for COVID-19 using the logistic growth model and the multi-wave Richards curve development model. The changepoint detection methods used include the interpolation method, the Pruned Exact Linear Time (PELT) method, and the Binary Segmentation (BS) method. The results of the analysis using 9 countries show that the Richards model development can be used to analyze multi-wave data using changepoint detection so that the initial data used for prediction on the last wave can be determined precisely. The changepoint used is the coincident changepoint generated by the PELT and BS methods. The interpolation method is only used to find out how many pandemic waves have occurred in given a country. Several waves have been identified and can better describe the data. Our results can find the peak of the pandemic and when it will end in each country, both for a single-wave pandemic and a multi-wave pandemic.

Development of Rice Stem Maggot (Chlorops oryzae) in the Fields in Suweon (수원지방(水原地方)에 있어서 벼줄기굴파리의 발생경과(發生經過))

  • HWANG, C.Y.;LEE, Y.B.;KIM, .S.H.;LEE, M.H.;Choi, K.M.
    • Korean journal of applied entomology
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    • v.24 no.2 s.63
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    • pp.61-64
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    • 1985
  • This study was carried out to investigate the seasonal occurrence and developmental periods of Rice stem maggot (RSM), Chlorops oryzae Matsumura, at laboratory and in the fields in $1980{\sim}1982$. RSM occurred three generations a year. Peak of the first, second, and third generation was middle to late May, early July and middle September. Longevity of the first generation adult averaged 18.9 days and the oviposition was 50 eggs per fly. The eggs, larval and pupal period was 7, 25, 14 days respectively.

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A study on the effective fault current limiting characteristics of stacked coated conductors with stainless steel stabilizer (스테인리스 스틸 안정화재를 가진 coated conductor의 적층 유무에 따른 효과적인 사고전류 제한을 위한 연구)

  • Na, J.B.;Ahn, M.C.;Kim, M.J.;Kim, Y.J.;Yang, S.E.;Park, D.K.;Kim, H.M.;Seok, B.Y.;Ko, T.K.
    • Progress in Superconductivity and Cryogenics
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    • v.9 no.1
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    • pp.9-13
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    • 2007
  • Coated conductor(CC) is recently in actively progress for the research and development, and its can be used various stabilizer lot the specific requirements for each application. Among various superconducting applications, coated conductor applied to superconducting fault current limiters(SFCLS) bypasses fault current to its stabilizer, where the surge is abruptly reduced ; thus, stainless steel, which has large resistivity can be a suitable stabilizer for SFCLS. Despite high n-value of the YBCO, CC stabilized with stainless steel did not effectively limit the first peak fault current. In the short circuit test results of AMSC's 344S, a half period delay was observed between the fault and the generation of resistance(60Hz). In this paper, we performed short-circuit experiments with stacked and unstacked CC and compared the test results to analyze effective fault current limiting characteristics. we compared time of the generated resistance as the fault current limiting characteristics and made the samples one is the stacked CC and the other is unstacked CC. These samples were used equal numbers of pieces of CC. In addition, comparison and analysis was made for the stacked structure by measuring fault current limiting characteristics with respect to thermal insulation by impregnating with epoxy resin.

Spatio-Temporal Variation of Soil Respiration and Its Association with Environmental Factors in Bluepine Forest of Western Bhutan

  • Cheten Thinley;Baghat Suberi;Rekha Chhetri
    • Journal of Forest and Environmental Science
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    • v.39 no.1
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    • pp.13-19
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    • 2023
  • We investigated Soil respiration in Bluepine forest of western Bhutan, in relation to soil temperature, moisture content and soil pH and it was aimed at establishing variability in space and time. The Bluepine forest thrives in the typical shallow dry valleys in the inter-montane Bhutan Himalaya, which is formed by ascending wind from the valley bottom, which carries moisture from the river away to the mountain ridges. Stratified random sampling was applied and the study site was classified into top, mid, low slope and further randomized sample of n=20 from 30 m×30 m from each altitude. The overall soil respiration mean for the forest was found 2248.17 CO2 g yr-1 and it is ~613.58 C g yr-1. The RS from three sites showed a marginal variation amongst sites, lower slope (2,309 m) was 4.64 μ mol m-2 s-1, mid slope (2,631 m) was 6.78 μ mol m-2 s-1 and top slope (3,027 m) was 6.33 μ mol m-2 s-1 and mean of 5.92 μ mol m-2 s-1, SE=0.25 for the forest. Temporal distribution and variations were observed more pronounced than in the space variation. Soil respiration was found highest during March and lowest in September. Soil temperature had almost inverse trend against soil respiration and dropped a low in February and peak in July. The moisture in the soil changed across months with precipitation and pH remained almost consistent across the period. The soil respiration and soil temperature had significant relationship R2=-0.61, p=0.027 and other variables were found insignificant. Similar relationship are reported for dry season in a tropical forest soil respiration. Soil temperature was found to have most pronounced effect on the soil respiration of the forest under study.

Growth and maturation period of a brown alga, Scytosiphon lomentaria(Lyngbye) Link in a natural habitat of Sodol, Jumunjin, eastern coast of Korea (한국 동해안 주문진의 자연산 고리매(Scytosiphon lomentaria)의 생장과 성숙주기)

  • Myeong Seok Han;Chan Sun Park;Eun Kyoung Hwang
    • Korean Journal of Environmental Biology
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    • v.40 no.2
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    • pp.206-213
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    • 2022
  • Ecological characteristics of a brown alga, Scytosiphon lomentaria, were investigated from January 2021 to December 2021 in its natural habitat off Sodol, Jumunjin, eastern coast of Korea. The S. lomentaria population at the site formed widespread patches on mid shore. During the investigation, environmental conditions including seawater temperature, salinity, and dissolved oxygen were monitored at the site. Growth and maturation of the S. lomentaria population were identified through qualitative and quantitative investigations. An estimation of the effective cumulative temperature for maturation of the alga was obtained based on growth data and a biological zero temperature of 8℃. Sporangia were observed from February to May when seawater temperatures ranged from 7.7℃ to 16.4℃. A maturation peak was detected in April when seawater temperature was 12.1℃. After zoospore release, the alga became bleached and only the crust remained after June. Developmental initiation of the thallus occurred at temperatures above 8℃. Its maturation required approximately 162 degree-days.

Long term variations of fish assemblage in the coastal waters Bukchon-ri, northern part of Jeju Island from 2012 to 2022 (제주도 북부 북촌리 연안에서 어획된 어류군집의 장기변화(2012~2022))

  • Jun-Cheol KO;Bo-Yeon KIM;Song-Heon HAN;Min-Sun KIM;Jung-Hyun KWAK
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.59 no.4
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    • pp.301-314
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    • 2023
  • Long term variations of fish assemblage in the coastal waters of Bukchon-ri were determined using samples collected by trammel net from 2012 to 2022. Water temperature increased by 0.4℃ in 2022 that was less then 2012. During the survey period, a total of 95 species (53 families and 15 orders) of fishes were identified, Scorpaeniformes (five families and 22 species) and Perciformes (25 families and 39 species) accounted for 73% of the total number. The number of species was higher in summer than winter, showing a peak in summer at 66 species and lower in winter and autumn at 45 species. The number of individuals and the biomass peaked in summer at 1,238 individuals and 280.1 kg, and were the lowest in autumn at 597 individuals and 155.4 kg. The annual diversity index, evenness index and richness index were appeared 2.11-2.80, 0.64-0.80 and 4.70-7.34 at each years. The dominance index were appeared highest in 2014 while 2021 were appeared the lowest in 2017. The subtropical fishes were identified total of 38 species (40.0%) and the number of species was higher in 2022 at 22 (52.4%) species and lower in 2015-2017 at each 10 (31.3-37.0%) species. The dominant species of subtropical fishes were appeared rabbit fish (Siganus fuscescens), boxfish (Ostracion immaculatus), smallscale blackfish (Girella melanichthys), flag fish (Goniistius zonatus), stripey (Microcanthus strigatus), rock porgy (Oplegnathus punctatus), and bluestriped angelfish (Chaetodontoplus septentrionalis) in study sites.

A Study on the Gonadal Maturation and Egg-Stripping by Hormone Treatments of Tiger Puffer, Takifugu rubripes (자주복, Takifugu rubripes의 성성숙과 호르몬 처리에 의한 인공채란에 관한 연구)

  • YANG Sang-Geun;LEE Young-Don;PYEN Choong-Kyu
    • Journal of Aquaculture
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    • v.7 no.4
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    • pp.189-205
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    • 1994
  • Formerly, adult-tiger puffer, Takifugu rubripes with ova caught in the sea, were used for seedling production. But it was difficult to secure naturally-ripened adults. For the purpose of adult tiger puffer in captivity, this study was carried out. To determine the growth 220 tiger puffers hatched in 1990 (3-year-old) and 1991 (2-year-old) were used. For spawning and egg incubation leading to fry development, eggs were stripped from tiger puffers hatched in 1988 (5-year-old) and 1990 (3-year-old) through human chorionic gonadotropin (BCG) treatments. In May, 1993, mean body length and mean body weight of 2-year-old tiger puffer were $30.72\pm1.35cm\;and\;1,048\pm228 g,$ and that of 3-year-old tiger puffers were $36.02\pm1.17cm$ and $1,402\pm66g$ respectively. The relationship between body length (L) and body weight (W) of 2-year-old the tiger puffers during the experiment period was represented as $W\;=\;1.7892L^{31524}\times10^5$ (r= 0.9436) and that of 3-year-old, $W=\;3.2840L^{36099}\times10^6$ (r= 0.9070) respectively. The GSI in female 2-year-old-fish changed from $0.23\times0.l2\;to\;0.74\pm0.08$, during the experiment period, and in male it didn't change remarkably until November, but thereafter it increased and showed a peak of $8.69\pm5.09$. The GSI of 3-year-old-fish showed a peak of $8.05\pm5.58$ in April in female and $12.65\pm4.60$ in May in male. The change of HSI in 3-year-old-fish was correlative to the change of GSI, but in 2-year-old-fish it was little correlative. In female gonad of 2-year-old tiger puffer, the mature oocytes reached $350{\mu}m$ in April, but thereafter they didn't spawn and became atrophied. But in male gonad, a great number of spermatozoa were crowded in the testicular lobuli in April. Female gonad of 3-year-old tiger puffer had the mature oocytes of 650 pm in March and the ripe oocytes, $900{\mu}m$ in April. Male testis development was similar to that of 2-year-old-fish. Egg-stripping after hormone treatments was possible past 139 hours and 142 hours from each of two 5-year-old-fish (500IU/kg, BW), and after 114 hour from a 3-year-old-fish (1,000 IU/kg, BW) under water temperature $16.3\~17.8^{\circ}C$. Eggs stripped amounted was 650 g and 400 g from two 5-year-old-fish and 610 g from the 3-year-old-fish, and fertilization rates were $98.0\%,\;97.4\%\;and\;96.5\%$ respectively. All the hatched larvae devloped into normal fry.

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Development of Movement Analysis Program and its Feasibility Test in Streotactic Body Radiation Threrapy (복부부위의 체부정위방사선치료시 호흡에 의한 움직임분석 프로그램 개발 및 유용성 평가)

  • Shin, Eun-Hyuk;Han, Young-Yih;Kim, Jin-Sung;Park, Hee-Chul;Shin, Jung-Suk;Ju, Sang-Gyu;Lee, Ji-Hea;Ahn, Jong-Ho;Lee, Jai-Ki;Choi, Doo-Ho
    • Progress in Medical Physics
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    • v.22 no.3
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    • pp.107-116
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    • 2011
  • Respiratory gated radiation therapy and stereotactic body radiation therapy require identical tumor motions during each treatment with the motion detected in treatment planning CT. Therefore, this study developed a tumor motion monitoring and analysis system during the treatments employing RPM data, gated setup OBI images and a data analysis software. A respiratory training and guiding program which improves the regularity of breathing was used to patients. The breathing signal was obtained by RPM and the recorded data in the 4D console was read after treatment. The setup OBI images obtained gated at 0% and 50% of breathing phases were used to detect the tumor motion range in crenio-caudal direction. By matching the RPM data recorded at the OBI imaging time, a factor which converts the RPM motion to the tumor motion was computed. RPM data was entered to the institute developed data analysis software and the maximum, minimum, average of the breathing motion as well as the standard deviation of motion amplitude and period was computed. The computed result is exported in an excel file. The conversion factor was applied to the analyzed data to estimate the tumor motion. The accuracy of the developed method was tested by using a moving phantom, and the efficacy was evaluated for 10 stereotactic body radiation therapy patients. For the sine wave motion of the phantom with 4 sec of period and 2 cm of peak-to-peak amplitude, the measurement was slightly larger (4.052 sec) and the amplitude was smaller (1.952 cm). For patient treatment, one patient was evaluated not to qualified to SBRT due to the usability of the breathing, and in one patient case, the treatment was changed to respiratory gated treatment due the larger motion range of the tumor than treatment planed motion. The developed method and data analysis program was useful to estimate the tumor motion during treatment.