• Journal of Oral Medicine and Pain
• /
• v.25 no.2
• /
• pp.145-151
• /
• 2000

The present study was performed to investigate the relationship between the salivary flow rate and the interpretation results of salivary scan in the patients with dry mouth. Twenty-five patients with dry mouth who visited the Dept. of Oral Medicine & Oral Diagnosis, Seoul National University Dental Hospital, were included. The unstimulated whole salivary flow rate was determined by the spitting method and the stimulated whole salivary flow rate was measured with gum-base chewing. Salivary scan was performed after the infusion of $^{99m}technetium$ pertechnetate(Tc) and interpreted. The obtained results were as follows: 1. The unstimulated and stimulated whole salivary flow rate were significantly decreased compared to normal value, which reflected the extensive destruction of salivary gland function in the patients with dry mouth. 2. The unstimulated and stimulated whole salivary flow rate were decreased in the group with decreased function in salivary scan compared with the group with normal function in salivary scan. However, there was no statistical significance between groups. 3. The difference between the stimulated and unstimulated whole salivary flow rates was greater in the group with normal function in salivary scan compared with the group with decreased function in salivary scan. 4. There was significant positive correlation between the stimulated and unstimulated whole salivary flow rates. The level of correlation was higher in the group with decreased function in salivary scan than the group with normal function in salivary scan. Collectively, these data suggested that salivary scan had the limited value. The comprehensive evaluation including history taking, clinical examination, clinical laboratory as well as the measurement of salivary flow rate are need for patients with dry mouth.

• Korean Journal of Radiology
• /
• v.21 no.7
• /
• pp.829-837
• /
• 2020

Objective: The aim of this study was to investigate the prognostic value of the maximum standardized uptake value (SUV_max) measured while restaging with F-18 fluorodeoxyglucose (¹⁸F-FDG) positron emission tomography/computed tomography (PET/CT) to predict the 3-year post-recurrence survival (PRS) in patients with recurrent gastric cancer after curative surgical resection. Materials and Methods: In total, 47 patients with recurrent gastric cancer after curative resection who underwent restaging with ¹⁸F-FDG PET/CT were included. For the semiquantitative analysis, SUV_max was measured over the visually discernable ¹⁸F-FDG-avid recurrent lesions. Cox proportional-hazards regression models were used to predict the 3-year PRS. Differences in 3-year PRS were assessed with the Kaplan-Meier analysis. Results: Thirty-nine of the 47 patients (83%) expired within 3 years after recurrence in the median follow-up period of 30.3 months. In the multivariate analysis, SUV_max (p = 0.012), weight loss (p = 0.025), and neutrophil count (p = 0.006) were significant prognostic factors for 3-year PRS. The Kaplan-Meier curves demonstrated significantly poor 3-year PRS in patients with SUV_max > 5.1 than in those with SUV_max ≤ 5.1 (3-year PRS rate, 3.5% vs. 38.9%, p < 0.001). Conclusion: High SUV_max on restaging with ¹⁸F-FDG PET/CT is a poor prognostic factor for 3-year PRS. It may strengthen the role of ¹⁸F-FDG PET/CT in further stratifying the prognosis of recurrent gastric cancer.

• The Korean Journal of Emergency Medical Services
• /
• v.8 no.1
• /
• pp.117-126
• /
• 2004

In general, the patients who transferred to the hospital by 119 rescue service at night go to the emergency room(ER) of general hospital rather than that of their nearby the 1st(clinic) and 2nd(local hospital) hospital. And the hospital is mainly selected not by 119 EMST but by patients or his/her conservators. Therefore we had studied retrospectively with emergency situation diary and medical chart for 697 patients of being transferred to one emergency medical center for 6 months since January 2004, and results are as follows. 1. The 280 patients(42.5%) of being transferred hospital at night by 119 rescue service were not emergency case and their average staying time in hospital was about $7.15{\pm}10.06$ minutes. 2. Transfer time was distributed in each time intervals of 1819, 2021, 2223, and 2401 and patients ratio in each intervals were 15.1%, 17.8%, 16.4%, and 15.2%. 3. In response of ambulance, the average time from the spot to the hospital was $14.53{\pm}9.27min$. and average distance of that was $7.95{\pm}9.21km$. 4. Diseases rather than traffic accidents or traumatic injury were main causes of ambulance calling and its value was 533(76.5%), and accidents were mainly occurred in patients' house and its value was 479(68.7%). 5. In time of transfer by 119 rescue service, hospital was mainly selected by patient/conservator and its value was 648(93.0%). In result. the hospital was selected not by EMST but by patient/conservator. 6. The case that the 1st grade EMT was rode in ambulance was 161(23.1%), and the case that 2nd EMT and emergency team member who educated for emergency were rode in ambulance were 504(72.3%). So the number of the 1st grade EMT was short in fire station of Kwangju metropolitan city than other city. 7. The first aids for patients before reaching hospital were limited to oxygen inhalation, airway control, and BLS for maintaining limbs and spine. So it seems to be a simple patients transfer. Consequently, to establish an efficient emergency medical system, it has been thought that it should be advanced a moderate education and public information about the appropriate use of emergency medical system toward citizen, and also need the hospital selection by the patients categorizing standards for 119 rescue service member, securing the 1st grade EMT, appropriate first-aids education, and securing professional human power in emergency room of the Ist(clinic) and 2nd(local hospital) hospital at night.

• Journal of Yeungnam Medical Science
• /
• v.38 no.4
• /
• pp.337-343
• /
• 2021

Background: Chromogranin A (CgA) levels have been reported to predict mortality in patients with heart failure. However, information on the prognostic value and clinical availability of CgA is limited. We compared the prognostic value of CgA to that of previously proven natriuretic peptide biomarkers in patients with acute heart failure. Methods: We retrospectively evaluated 272 patients (mean age, 68.5±15.6 years; 62.9% male) who underwent CgA test in the acute stage of heart failure hospitalization between June 2017 and June 2018. The median follow-up period was 348 days. Prognosis was assessed using the composite events of 1-year death and heart failure hospitalization. Results: In-hospital mortality rate during index admission was 7.0% (n=19). During the 1-year follow-up, a composite event rate was observed in 12.1% (n=33) of the patients. The areas under the receiver-operating characteristic curves for predicting 1-year adverse events were 0.737 and 0.697 for N-terminal pro-B-type natriuretic peptide (NT-proBNP) and CgA, respectively. During follow-up, patients with high CgA levels (>158 pmol/L) had worse outcomes than those with low CgA levels (≤158 pmol/L) (85.2% vs. 58.6%, p<0.001). When stratifying the patients into four subgroups based on CgA and NT-proBNP levels, patients with high NT-proBNP and high CgA had the worst outcome. CgA had an incremental prognostic value when added to the combination of NT-proBNP and clinically relevant risk factors. Conclusion: The prognostic power of CgA was comparable to that of NT-proBNP in patients with acute heart failure. The combination of CgA and NT-proBNP can improve prognosis prediction in these patients.

• Journal of Korean Medicine Rehabilitation
• /
• v.20 no.1
• /
• pp.109-117
• /
• 2010

Objectives : The aim of this study was to investigate the different of yangdorak diagnosis between low back pain patients and medical checkup group. Methods : We analyzed the measurement value of yangdorak on 103 patients with low back pain and 103 medical checkup persons in Korean males from March 1st, 2007 to September 30th, 2008 by using yangdorak(MEDIRA, Neomyth Co., Korea). Results : 1. In comparing results on the yangdorak general mean, low back pain group is statistically significant in comparison with medical checkup group(p<0.001). 2. In comparing results on each meridian yangdorak value, they were statistically significant between two groups(p<0.001). 3. In comparing result on the distance of yangdorak value from the mean, they were statistically significant between two groups at the Bladder-meridian(p<0.05), but not at the Kidney-meridian. Conclusions : This results suggest that yangdorak may be used for a method to objective clinical examination. But further studies are required for a use of practical indicator.

• The Journal of the Korea Contents Association
• /
• v.10 no.5
• /
• pp.259-266
• /
• 2010

Clostridium difficile-associated disease (CDAD) is an important nosocomial infectious diarrhea and is associated with antibiotic use. Recently, incidence of C. difficile has been increasing in hospitals. A total of 1,329 stool specimens were examined from January, 2005 to December, 2008. This study analyzed the incidence and clinical characteristics of C. difficile infections on them. Out of 1,329 stool specimens, 283 specimens showed toxin A/B positive, using EIA. The positive rate was 21.2%; with the highest incidence among and above the 70years old. On endoscopy, psedo membranous colitis was found in 57.7%, and 19.5% of patients were normal. Pathologic finding showed PMC in 26.8% of patients, AAC in 52.2%. C. difficile was associated with PMC, however, endoscopic and pathologic findings tests showed normal to PMC.

• Textile Coloration and Finishing
• /
• v.21 no.1
• /
• pp.21-29
• /
• 2009

In order to enhance the functionality of a cotton fabric actually used as a clothing material for patients, the fabrics were treated with a chitosan/nanosilver mixed solution. The nanosilver had excellent biocompatibility, provided expectation of an additional performance, did not harm human beings, and supplements chitosan, which was disadvantaged if used alone for fabric treatment. The nanosilver was mixed thereto and a treatment effect due to a mixing ratio was considered. This study was observed through mechanical properties and hand value which were the important function. The treatment of chitosan/nanosilver mixed solution gave a smoother surface than the treatment of chitosan alone. As a result of evaluation of the forms according to KES-FB system, Koshi was deduced, and both Numeri and Fukurami were increased. Thereby, the cotton fabric was a little smooth to provide elasticity, due to the treatment of chitosan/nanosilver mixed solution. THV of the treated fabrics calculated from this basis increased at all mixing ratio as compared with the untreated fabric. The fabrics treated with chitosan/nanosilver mixed solution were shown a better THV than the fabric treated with chitosan alone.

• The Journal of Korean Medicine
• /
• v.45 no.1
• /
• pp.139-149
• /
• 2024

Objectives: The aim of the study was to investigate the potential of Yangdorak diagnosis application against gallstone scanned by Ultrasound diagnosis. Method: For this aim, among 97 patients who had visited Julip Korean Medicine Clinic from July 2016 to June 2023, 30 patients with no gallstone as a control group and 67 patients with gallstone and diagnosed by ultrasonography, were subjected to Yangdorak diagnosis. Then, the changes in Gallbladder Meridian (GB) value as F5 AVE(average of left and right GB value) by Yangdorak were comparatively analyzed between gallstone and non-gallstone groups and statistical significance was evaluated by Tukey's multiple comparison test using Prism software. Results: After all subjects were evaluated by the Yangdorak and ultrasonography to assess the potential of the Yangdorak diagnosis for gallstone, it was noteworthy that the Yangdorak values relevant to F5 AVE of female gallstone group(N=36) were significantly (p<0.001) decreased compared to the control group (N=30), while there was no significance in male gallstone group(N=31). Also, it was recognized significant difference between male and female groups. Conclusion: Based on these results, if the Yangdorak value can be estimated from a decrease with clinical symptom in female patient, it is recommended to follow up the ultrasonography test for diagnosing the gallstone.

• Journal of Home Health Care Nursing
• /
• v.31 no.1
• /
• pp.56-65
• /
• 2024

Purpose: This study aimed to explore the association between demographic characteristics, hospitalization-related characteristics, and the severity of long-term hospitalization in a high-level general hospital, and to analyze the factors influencing decisions of all patients. Methods: General and clinical characteristics of the participants were analyzed using frequency, percentage, mean, and standard deviation. Differences in these characteristics, contingent upon whether a power source was requested, were analyzed using independent t-Test and Chi-squared tests. Logistic regression analysis was used to identify the factors related to the presence or absence of power requests. Results: The factors impacting the decision to refer a dependent variable include medical treatment (neurosurgery) (B=2.118, SE=0.960, p-value=.027, OR=8.314, 95% CI=1.267-54.551), infection isolation (CRE) (B=1.336, SE=0.666, p-value=.045, OR=3.804, 95% CI=1.032-14.021), and the utilization of tertiary antibiotics (B=3.076, SE=1.362, p-value= .024, OR=21.663, 95% CI=1.502-312.530). Conclusion: This study found a significant association between medical treatment (neurosurgery), infection isolation (CRE), and the use of tertiary antibiotics as dependent variables. These findings indicate that continuous monitoring can contribute to a reduction in long-term financial burdens.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.6
• /
• pp.2215-2217
• /
• 2015

Background: This systemic analysis was conducted to to evaluate the application value of positron emission tomography/computed tomography (PET/CT) in early diagnosis of lung cancer. Methods: Clinical studies evaluating the application value of PET/CT for patients underwent PET/CT imaging. The histological diagnosis served as the standard of truth. Results: Four clinical studies which including 1330 patients with pulmonary spaceoccupying lesions were considered eligible for inclusion. Systemic analysis suggested that, in all 1330 patients, pooled sensitivity was 98.7% (1313.2/1330) and specificity was 58.2%(276.85/476). Conclusion: This systemic analysis suggests that integrated PET/CT imaging provides high sensitivity, and reasonably high specificity, and could be applied for early diagnosis of lung cancer.