• 제목/요약/키워드: Pathological Symptoms

검색결과 383건 처리시간 0.021초

사상체질분류검사지(四象體質分類檢査紙)(QSCC) II 에 의한 소음인(少陰人) 진단(診斷)의 타당성(妥當性) 연구(硏究) (A study on the validity to make a diagnosis of Soeumin by QSCC II (Questionnaire for the Sasang Constitution Classification II))

  • 이수경;이의주;고병희;송일병;김상복
    • 사상체질의학회지
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    • 제12권2호
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    • pp.94-103
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    • 2000
  • The purpose of this study is to examine validity to Soeum scales by QSCC II. For this study, the objects are 336 patients who were made a diagnosis of Soeumin and 422 patients of other constitutions in Oriental Medicine & Western Medicine Cooperative Health Examination Center KyungHee University Medical Center. A systematic analysis has been made and the results are as follows. 1. We made a frequency analysis in 758 examinees' questions and concluded that 35 questions, among which 30 questions were existing and 5 were new, had statistical significance in making a diagnosis of Soeumin by more than 10% in comparison with answer frequency of other constitutions. 2. Because confidence coefficient of 0.8011 revised Soeum scales(35) rises up as compared with that of 0.6319 existing Soeum scales(51), I think revised Soeum scales reflect trait of Soeumin well and it is liable to shorten question time by controling questions. 3. Soeumin's discrimination probability in Soeumin was 55.4% by QSCCII, but that rises up to 64.3% by discriminant function made by revised Soeum scales. So there is statistical significance in discriminant function. 4. When questions in QSCCII are divided into body-spirit(體形氣像), looks-attitude(容貌詞氣), temper- talent(性質才幹), continuous mind(恒心), avarice(心慾), physiological symptoms(生理的 證) and pathological symptoms(病理的 證), response frequency and constitution discrimination probability falls in questions about avarice and pathological symptoms.

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ACUTE INFECTIOUS BURSAL DISEASE IN CHICKENS : PATHOLOGICAL OBSERVATION AND VIRUS ISOLATION

  • Chowdhury, E.H.;Islam, M.R.;Das, P.M.;Dewan, M.L.;Khan, M.S.R.
    • Asian-Australasian Journal of Animal Sciences
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    • 제9권4호
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    • pp.465-469
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    • 1996
  • Pathological and virological investigations were conducted on suspected outbreaks of infectious bursal disease (IBD) in a broiler farm and five pullet-raising poultry farms of Mymensingh and Tangail districts of Bangladesh. About 80 to 100 percent chicks were affected at the age of 26 to 45 days and mortality varied from 20 to 30 percent in broilers and 40 to 80 percent in layer chicks. Signs, symptoms, gross and microscopic lesions were typical of acute IBD. Several isolates of virus could be obtained by embryo inoculation and the virus was diagnosed as infectious bursal disease virus (IBDV) by agar gel immunodiffusion test (AGID). The virus isolate belonged to the very virulent pathotype of IBDV causing 100 percent mortality in three weeks old chicks on experimental infection.

Sino-Bronchiectasis 에 대한 임상적 고찰 (Clinical and Pathological Study of Sino-bronchiectasis)

  • 김종원;서정회;최인환
    • Journal of Chest Surgery
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    • 제6권2호
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    • pp.151-158
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    • 1973
  • Author studied the pathogenesis of Sino-bronchiectasis with review of clincal and pathological findings of resected lungs in 24 eases of bronchiectasis,and the results were as follows: 1. Of the 24 eases of bronchiectasis, Sino-bronchiectasis were found in 11 cases and these cases most commonly, developed in first and second decade of life. In a majority of these cases,the main symptoms were the signs of wet bronchiectasis. 2. The typical roentgenograrn changes of plain chest x rays were increase in size and loss of definition of the markings and bronchographically revealed the cylindrical or tubular form in majority of these cases. 3. Pathologically Sino-bronchiectasis involved specific segmental areas of the lungs such as left basal and S4+5 segments and revealed commonly tubular dilatation. The most common findings of bronchial wall of dilated bronchus were the inflammatory cellular infiltration and cylindrical hyperplasia of mucus epithelial layers. 4. It was suspected that there were some causal relations in pathogenesis between chronic sinusitis and bronchiectasis.

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Hsp27 Reduces Phosphorylated Tau and Prevents Cell Death in the Human Neuroblastoma Cell Line SH-SY5Y

  • Ahn, Junseong;Kim, Hyeseon;Park, Jong-Sang
    • Bulletin of the Korean Chemical Society
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    • 제34권5호
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    • pp.1503-1507
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    • 2013
  • The two major symptoms characterizing Alzheimer's disease are the formation of amyloid-${\beta}$ extracellular deposits in the form of senile plaques and intracellular neurofibrillary tangles (NFTs) that consist of pathological hyperphosphorylated tau protein aggregated into insoluble paired helical filaments (PHFs). Neurons of the central nervous system have appreciable amounts of tau protein, a microtubule-associated protein. To maintain an optimal operation of nerves, the microtubules are stabilized, which is necessary to support cell structure and cellular processes. When the modified tau protein becomes dysfunctional, the cells containing misfolded tau cannot maintain cell structure. One of the pathological hallmarks of Alzheimer's disease is hyperphosphorylated tau protein. This paper shows that the small heat shock protein from humans (Hsp27) reduces hyperphosphorylated tau and prevents hyperphosphorylated tau-induced cell death of the human neuroblastoma cell line SH-SY5Y.

위식도 역류에 대한 후두인두부에서 산도 검사의 의의 (Clinical Significance of Hypopharyngeal pH Monitoring in Gastroesophageal Reflux)

  • 정다운;김소희;김은영;문경래
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제8권2호
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    • pp.143-149
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    • 2005
  • 목 적: 병적 위식도 역류 환자에서 후두인두부 산도를 검사하여 후두인두부 역류와 호흡기 증상과의 상관관계를 연구하고자 하였다. 방 법: 2003년 2월부터 2004년 9월까지 잦은 구토 등 위식도 역류가 의심되는 증상이 있거나 만성 재발성 호흡기 증상이 있어 24시간 후두인두부와 식도에서 산도 검사를 실시한 39명 중 병적 위식도 역류를 보인 29명을 대상으로 하였다. 병적 위식도 역류의 기준은 95백분위수 이상 역류 지표를 병적 역 류로 정의하였고, 후두부 인두 산 역류의 기준은 식도에서 pH 4 이하로 떨어짐과 동시에 후두부 인두에서 pH가 4 이하로 떨어지는 것으로 정의하였다. 결 과: 1. 산도 검사를 실시한 39명에서 호흡기 증상이 있는 7명 중 6명(86.%), 호흡기 증상이 없는 32명 중 23명(72%)에서 병적 위식도 역류를 보였다. 2. 호흡기 증상으로는 반복되는 폐렴 2명, 크룹 1명, 후두연화증 1명, 천식 2명 등이었다. 3. 호흡기 증상을 동반한 병적 역류군에서 후두인두부와 식도의 역류 지표를 비교하면 5분 이상 지속된 역류의 횟수 제외한 역류 지수, 총 역류 횟수, 최 장 역류 시간 등에서 통계학적으로 의의있는 차이를 보였다. 4. 호흡기 증상을 동반하지 않은 병적 역류군에서 후두인두부와 식도의 모든 역류 지표들이 유의한 차이를 보였다. 5. 식도에서 호흡기 증상을 동반한 병적 역류군과 호흡기 증상을 동반하지 않은 병적 역류군의 역류지표를 비교하면 총 역류 횟수를 제외한 역류 지수, 최장 역류 시간, 5분 이상 지속된 역류의 횟수에서 통계학적 의의가 없었다. 6. 후두부 인두에서 호흡기 증상을 동반한 병적 역류군과 호흡기 증상을 동반하지 않은 병적 역류군의 역류 지표를 비교하면 모든 항목에서 통계학적 의의가 없었다. 결 론: 병적 위식도 역류 환자에서 호흡기 증상 유무와 관계없이 후두인두부의 산도 검사 결과는 통계학적 의의가 없으므로 만성 호흡기 질환에서 후두인두부 역류와의 상관관계의 규명에 후두인두부 산도 검사의 유용성에 대한 재고가 필요하다.

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허약아(虛弱兒) 증상 연구를 통한 인터넷 중독의 한의학적 접근 (Oriental Medical Research about Internet Addiction by Study of the Weak Children Symptoms)

  • 김현지;박은정
    • 대한한방소아과학회지
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    • 제22권2호
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    • pp.51-67
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    • 2008
  • Objectives : The purpose of this study is to research the internet addiction and the Weak children. Methods : Total 400 of 5th and 6th grade JeonJu Elementary student children consisted with 203 men, 197 women were chosen for this study. They answered questionnaires of the internet addiction and the Weak children on June 12th, 2008. Results : 75% were general internet user, latent danger user group was 14.7%, high danger user group was 10.3%. The mean of the general weak children was the highest and then the group of children who had Heart, the Lung, the Liver, the Spleen, the Kidney problems were followed. These showed the relationships with living styles, especially eating patterns and parents' concerns about children's internet use. The more serious internet addiction was, the more the weaker children symptoms were answered significantly. The heart weak children symptoms were found in latent-high danger internet user group. Conclusions : In conclusion, the physical and psychological symptoms of the internet addiction children were resulted by the disturbance of Qi and the pathological change of internal organs.

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중풍증상(中風症狀)과 함께 나타난 Marchiafava-Bignami 병 1예 보고 (A case report of Marchiafava-Bignami disease with stroke symptoms)

  • 이소연;윤현덕;박치상;박창국;장우석
    • 대한한방내과학회지
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    • 제25권3호
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    • pp.569-572
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    • 2004
  • Marchiafava-Bignami Disease(MBD) is a rate disease caused by chronic alcohol abuse and involves the degeneration of corpus callosum pathological in character. Until recently there was no method to diagnose MBD except postmortem examination, but nowadays rodiology has advanced increasingly, so MBD can be diagnosed correftly and easily. A case of MBD with stroke symptoms is reported. A 56-year-old man who has been a heavy alcoholic for several years was admitted with stroke symptoms such as stuporous mental, hemi-extremities weakness, dysphasia and dysphagia. After treatment these symptoms were improved.

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우측 경련성 사경 수술적 치료 후 좌측에 발병한 경련성 사경 환자에서 시행된 국소마취제 신경차단술의 임상효과 - 증례보고 - (Positive Effects of Local Anesthetic Nerve Blocks for a Patient with Newly Developed Left Side Spasmodic Torticollis after Surgical Intervention of Right Side Spasmodic Torticollis - A case report -)

  • 최창훈;최진환;성춘호
    • The Korean Journal of Pain
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    • 제20권2호
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    • pp.246-250
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    • 2007
  • We report here on a case of right side spasmodic torticollis (ST) that was refractory to botulinum toxin type A injection and medication. The patient finally underwent a selective ramisectomy with ipsilateral sternocleidomastoid muscle (SCM) resection, but the remaining symptoms slowly aggravated, and a contralateral left side SCM spasm began. As conservative therapy for reducing the spasmodic symptoms, accessory nerve block, upper cervical plexus block and stellate ganglion block were performed twice in a week. After 6 months, the spasmodic symptoms significantly decreased. The Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) decreased by more than 70%. After one year of serial intermittent local anesthetic blockade therapy, the patient became almost free from the original ST symptoms (TWSTRS = 1). Serial local anesthetic interventions for the ST patient may have a beneficial role on the pathological peripherocentral neural activity of the ST patient and can modulate motor-sensory integration in the patient.

Frontal Alpha Asymmetry, Heart Rate Variability, and Positive Resources in Bereaved Family Members with Suicidal Ideation after the Sewol Ferry Disaster

  • Jang, Kuk-In;Lee, Sangmin;Lee, Seung-Hwan;Chae, Jeong-Ho
    • Psychiatry investigation
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    • 제15권12호
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    • pp.1168-1173
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    • 2018
  • Objective After the Sewol ferry disaster, bereavement with suicidal ideation was a critical mental health problem that was accompanied by various neuropsychological symptoms. This study examined the frontal alpha asymmetry (FAA), heart rate variability (HRV), and several psychological symptoms in bereaved family members (BFM) after the Sewol ferry disaster. Methods Eighty-three BFM after the Sewol ferry disaster were recruited. We assessed FAA, HRV, and psychological symptoms, including depression, post-traumatic stress, post-traumatic growth factor, anxiety, grief, and positive resources, between BFM with the presence and absence of current suicidal ideation. Results Compared to BFM without suicidal ideation, BFM with suicidal ideation showed a higher FAA with right dominance. Significant differences in psychological symptoms were observed between the groups. In BFM with suicidal ideation, the low: high frequency (LF:HF) ratio correlated with social resources and support. Conclusion The FAA and LF:HF ratio may be biomarkers that represent the pathological conditions of BFM with suicidal ideation. If researched further, they may shed light on the interaction between bereavement with suicidal ideation and social resources for therapeutic intervention.

선천성심질환(先天性心疾患)의 심폐기(心肺器) 개심수술(開心手術) - 4례(例) 보고(報告) - (Open Heart Surgery of Congenital Heart Diseases -Report of Four Cases-)

  • 김근호;박영관;지행옥;김영태;이종배;정윤채;오철수
    • Journal of Chest Surgery
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    • 제9권1호
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    • pp.1-9
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    • 1976
  • The present. study reports four cases of congenital heart diseases, who received open heart surgery by the Sarn's Heart-Lung-Machine in the department of Thoracic Surgery, Hanyang University Hospital during the period between July 1975 and May 1976. The Heart-Lung-Machine consisted of the Sarn's five head roller pump motor system (model 5000), heat exchanger, bubble trap, the Rygg-Kyvsgaard oxygenator, and monitors. The priming of pump oxygenator was carried out by the hemodilution method using Hartman's solution and whole blood. Of the four cases of the heart diseases, three whose body weight were below 30kg, received the partial hemodilution priming and the remaining one whose body weight was 52kg received the total hemodilution priming with Hartman's solution alone. The rate of hemodilution was in the average of 60.5ml/kg. Extracorporeal circulation was performed at the perfusion flow rate of the average 94.0ml/kg/min, and at the moderate hypothermia between 35'5"C and 30'5"C of the rectal temperature. In the total cardiopulmonary bypass, arterial blood pressure was anged between 30 mmHg and 85 mmHg, generally maintaining over 60 mmHg and venous pressure was measured between 4 and $23cmH_2O$, generally maintaining below $10cmH_2O$. The first case: The patient, a nine year old girl having the symptoms and physical signs typical to cardiac anomaly was definitely diagnosed as isolated pulmonary stenosis through the cardiac catheterization. There was, however, no cyanosis, no pathological finding by X-ray and E.C.G. tracings. The valvulotomy was performed through the arteriotomy of pulmouary artery under the total cardiopulmonary bypass. Postoperative course of the patient was uneventful, and murmur and the clinical symptoms disappeared. The second case: A 12 year old boy with congenital heart anomaly was positively identified as having ventricular septal defect through the cardiac catheterization. As in the case with the first case, the patient exhibited the symptoms and physical signs typical to cardiac anomaly, but no pathological abnormality by X-ray and E.C.G. tracings. The septal defect was localized on atrioventricular canal and was 2 by 10 mm in size. The septal defect was closed by direct simple sutures under the cardiopulmonary bypass. Postoperative hemodynamic study revealed that the pressure of the right ventricle and pulmonary artery were decreased satisfactory. Postoperative course of the patient was uneventful, and murmur and the clinical symptoms disappeared. The third case: The patient, a 19 year old girl had been experienced the clinical symptoms typical to cardiac anomaly for 16 years. The pink tetralogy of Fallot was definitey diagnosed through the cardiac catheterization. The patient was placed on an ablolute bed rest prior to the operation because of severe exertional dyspnea, fatigability, and frequent syncopal attacks. However, she exhibited very slight cyanosis. Positive findings were noted on E.C.G. tracings and blood picture, but no evidence of pathological abnormality on X-ray was observed. All of the four surgical approaches such as Teflon patch closure (3 by 4cm in size) of ventricular septal defect, myocardial resection of right ventricular outflow tract, valvulotomy of pulmonary valvular stenosis, and pericardial patch closing of ventriculotomy wound were performed in 95 minutes under the cardiopulmonary bypass. Postoperative hemodynamic study revealed that the pressure of the right ventricle was decreased and pulmonary artery was increased satisfactorily. Postoperative course of the patient was uneventful, and murmur and the clinical symptoms disappeared. The fourth case: The patient, a 7 1/4 year old girl had the symptoms of cardiac anomaly for only three years prior to the operation. She was positively identified as having acyanotic tetralogy of Fallot by open heart surgery. The patient showed positive findings by X-ray and E.C.G. tracings, but exhibited no cyanosis and normal blood picture. All of the three surgical approaches, such a myocardial resection of hypertrophic sight ventricular outflow tract, direct suture closing of ventricular septal defect and pericardial patch closing of ventriculotomy wound were carried out in 110 minutes under the cardiopulmonary bypass. Postoperative hemodynamic study revealed that the pressure of the right ventricle was decreased and pulmonary artery was increased satisfactorily. Postoperative course of the patient was uneventful, and the symptoms disappeared.

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