• Title/Summary/Keyword: Pathological Symptoms

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Pathological Changes in Cultured Korean Catfish (Silurus asotus) Artficially Infected with Aeromonas veronii (Aeromonas veronii의 실험적 감염에 의한 양식 메기, Silurus asotus의 병리학적 변화)

  • Kim, Jin-Do;Do, Jeong-Wan;Choi, Hye-Sung;Seo, Jung-Soo;Jung, Sung-Hee;Jo, Hyae-In;Park, Myung-Ae;Lee, Nam-Sil;Park, Sung-Woo
    • Korean Journal of Environmental Biology
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    • v.31 no.4
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    • pp.486-492
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    • 2013
  • Recently, a new disease showing symptoms such as epidermal exfoliation and muscular necrosis occurred in cultured Korean catfish. Although the mortality of fishes was low but the economic damages owing to loss of commercial value were severe. The authors isolated the causative agent from diseased fish and observed pathological changes both in naturally and artificially infected fish. The causative bacteria was identified as Aeromonas veronii. Subsequently we observed the daily death and pathological symptoms of artificially infected fish with Aeromonas veronii. Symptoms of artificially infected fish were similar to those of naturally infected fish and all fish died within 7 days after infection. Histopathological changes on the naturally infected fish revealed severe congestion and necrotic degeneration in the liver, spleen and kidney. Some bacterial aggregates with inflammatory degeneration were observed in the heart, and congestion and fibrosis in the lamina propria of digestive tube were predominant. In artificially infected fish, skin erosion and necrotic degeneration of muscle tissue around injected region were particularly manifested. Degeneration of hepatocytes in liver and hyalic degeneration around ellipsoids in spleen were partially observed. However, there were no predominant signs in digestive tube in artificially infected fish.

A Myological Study of Hand Great Yin Lung Meridian Muscle System and Comparison with Deep Front Line in Anatomical Train (수태음폐경근의 근육학적 고찰 및 심부상지전방선과의 비교)

  • Kim, Myungkwan;Kim, Kyungmin;Jeon, Juhyun
    • Journal of Haehwa Medicine
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    • v.24 no.2
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    • pp.17-24
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    • 2016
  • Objectives : This study was aimed to widen range of comprehesion about meridian muscle system through myological study of meridian muscle system and comparison with deep front arm line in anatomical train Methods : We have studied the similarity and difference between Hand Great Yin Lung Meridian Muscle System and Deep Front Line in Anatomical Train through Principles of Meridians & Acupoints, publications about myology, Anatomical trains. Results : I. Like another advanced studies, muscular system of hand great yin showed similarity to deep front line in anatomical train. II. It is considered that muscular system of hand great yin contains Musculus abductor pollicis brevis, Musculus extensor hallucis longus, Musculus brachioradialis, Musculus biceps brachii, Musculus subclavius, Musculus pectoralis major. III. Comparing muscular system of hand great yin to deep front arm line in anatomical train it showed similarity to part of muscles and pathological symptoms. But it showed difference to part of muscles and pathological symptoms. Conclusions : Hand Great Yin Lung meridian muscle system showed similarity and difference to deep front arm line in anatomical train. Further studies would be needed.

Experience in Jang Jong-jeong's Vomiting Treatment (장종정(張從正) 토법(吐法)의 경험례)

  • Kim, Eui tae;Cha, Ung-Seok;Kim, Nam il
    • The Journal of Korean Medical History
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    • v.19 no.2
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    • pp.87-100
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    • 2006
  • Jang Jong-jeong thought that, because all diseases come from miasma, for treating diseases, it is important to attack or remove miasma infiltrating into the body. Thus, he treated diseases using three methods, namely, vomiting against miasma on the top, sweating against miasma on the surface, and diarrhea against miasma on the bottom. Among them, vomiting is rarely used in contemporary Oriental medicine, but still one of major disease treatment methods. Vomiting is quite meaningful in today's clinics and particularly effective for acute diseases, the miasma of which is in the upper chest. According to the present researcher's experiences, it is effective in cases that the pathological symptoms are observed in the upper chest such as early stroke, dyspepsia, chest congestion and congestion heat. For vomiting, the researcher applied Dokseongsan, Samseongsan, Gwachesan, Gangyeomtang, Bangpungtongseongsan, etc. Dokseongsan was used for vomiting in a cool way, and Samseongsan and Gwachesan were used for vomiting in a warm way. Bangpungtongseongsan was used when inner heat was choked up by the attack of external miasma and when the pathological symptoms of Bangpungtongseongsan were observed.

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A Systemic Review of Studies for Traditional Chinese Treatment of Intestinal Metaplasia - Research using CNKI (장상피화생(腸上皮化生) 치료에 대한 최신 임상 연구 동향 - CNKI 검색을 중심으로)

  • Lee, Bo-ram;Kim, Won-ill
    • The Journal of Internal Korean Medicine
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    • v.39 no.6
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    • pp.1085-1104
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    • 2018
  • Objectives: The purpose of this research is to investigate recent clinical studies of Intestinal Metaplasia (IM) based on a search of the China National Knowledge Infrastructure (CNKI). Methods: We investigated recent clinical studies of Oriental medicine therapies in traditional Chinese medical journals for IM through a CNKI search. 20 clinical articles published from 2010 to 2016 were analyzed. This study examined the authors, publication years, types of studies, criteria for diagnosis and evaluation, periods, purposes of study and articles classified by methods of treatment. Results: Most of articles were classified as randomized controlled trial. IM was diagnosed using gastroscopy, pathological examination and clinical symptoms in a high proportion of articles. The criteria for evaluation most frequently used were the effective ratios of clinical symptoms, gastroscopy and pathological tests. The methods of treatment in all studies were Chinese herb medicine. Acupuncture, acupoint injection therapy, and embedding therapy were also used in several studies. Conclusion: In this study, the Chinese treatment for IM was markedly effective. To improve the treatment of IM in Korea, many clinical studies and case reports are required, based on Chinese medicine.

The study on ShangHanLun BianMaiFa (2) (『상한론(傷寒論)·변맥법(辨脈法)』에 관한 연구(2))

  • Choi, Jong-Moon;Kim, Yun-Ju;Cho, Eun-Kyung;Hong, Jin-Woo;Shin, Sang-Woo
    • The Journal of Korean Medical History
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    • v.24 no.1
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    • pp.73-96
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    • 2011
  • The BianMaiFa chapter, which is the first chapter of SongBon ShangHanLun, is the scholarly description(專論) of the pulse and pathological mechanism but has not been studied and published yet. This study is about article 11-23 which is the second part of The BianMaiFa chapter. We compared the original texts within the editions, comparing and analyzing the annotations of successive dynastic medical group. The articles of The SongBon ShangHanLun BianMaiFa chapter 11-23 is consisted as is shown: article 11 12 13 state about a dignosis of yin-yang, deficiency-excess, fluid-humor from difference of a pulse shape and a sign of recovery from a disease, article 14 states about a prognosis of a disease according to a pulse, article 15 states about a pulse from which we predict a recovery, article 16 states about normal pulse according to season, article 17 states about ups and downs of a disease according to yin-yang of day and night, article 18 states about a location of a disease in connection with a pulse, article 19 states about a pathological mechanism of a diarrhea through a anterior tibial pulse(趺陽脈), a lesser yin pulse(少陰脈), article 20 states about a cause of disease, a symptom, a therapy about a floating and tight pulse(浮緊脈), article 21 states about a pathological mechanism of symptoms through a anterior tibial pulse(趺陽脈), article 22 states about a pulse, a pathological mechanism, symptoms caused by erroneous treatment, article 23 states about a pulse, a symptom, a therapy with internal heat. The BianMaiFa chapter 11-23 discussed a diagnosis, a prognosis of a disease, understanding of pathological mechanism through pulse. And The BianMaiFa suggests a various use of pulse.

Occurrence of Anthracnose on Chinese Mallow Caused by Colletotrichum malvarum

  • Kim, Wan-Gyu;Hong, Sung-Kee;Kim, Jin-Hee
    • Mycobiology
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    • v.36 no.2
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    • pp.139-141
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    • 2008
  • Anthracnose symptoms were frequently observed on leaves, petioles, and stems of Chinese mallow grown in Namyangju, Korea, during a disease survey performed in November, 2007. The disease incidence was as high as 30% in the 12 greenhouses investigated. A total of 38 isolates of the Colletotrichum species were obtained from the anthracnose symptoms, and all the isolates were identified as Colletotrichum malvarum based on their morphological and culture characteristics. Three isolates of the fungus caused anthracnose symptoms on leaves and stems following artificial inoculation, which were similar to those observed during the greenhouse survey. In this study, mycological and pathological characteristics of C. malvarum identified as causing anthracnose of Chinese mallow were clarified.

Acute Spontaneous Spinal Subdural Hematoma with Vague Symptoms

  • Chung, Jaehwan;Park, In Sung;Hwang, Soo-Hyun;Han, Jong-Woo
    • Journal of Korean Neurosurgical Society
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    • v.56 no.3
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    • pp.269-271
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    • 2014
  • Spinal subdural hematoma is a rarely reported disease and spontaneous spinal subdural hematomas (SSDH) without underlying pathological changes are even rarer. The patients usually show typical symtoms such as back pain, quadriplegia, paraplegia or sensory change. But rarely, patients may show atypical symptoms such as hemiparesis and misdiagnosed to cerebrovascular accident. We recently experienced a case of SSDH, where the patient initially showed vague symptoms, such as the sudden onset of headache which we initially misdiagnosed as subarachnoid hemorrhage. In this case, the headache of patient improved but the neck pain persisted until hospital day 5. Therefre, we conducted the MRI of cervical spine and finally confirmed SSDH. The patient was managed conservatively and improved without recurrence. In this case report, we discuss the clinical features of SSDH with emphasis on the importance of an early diagnosis.

Diagnosis and management of neurogenic orthostatic hypotension

  • Woohee Ju;Dong In, Sinn
    • Annals of Clinical Neurophysiology
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    • v.25 no.2
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    • pp.66-77
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    • 2023
  • Orthostatic hypotension is a sustained and pathological drop in blood pressure upon standing. Orthostatic hypotension can be due to non-neurogenic conditions or autonomic disorders. Impaired baroreflex-mediated vasoconstriction and insufficient release of norepinephrine play key roles in the pathophysiology of neurogenic orthostatic hypotension. Its common symptoms mainly related to inadequate cerebral blood flow include dizziness, lightheadedness, and syncope. It is crucial to differentiate neurogenic orthostatic hypotension from non-neurogenic orthostatic hypotension. For the management of neurogenic orthostatic hypotension, physicians should implement non-pharmacological methods and, if possible, reverse combined non-neurological conditions. Depending on severity of symptoms, pharmacological intervention may be tried after or with non-pharmacological methods. Its management should be individualized based on intensity of symptoms, comorbid conditions, drug side effects, and etiology. In this review, we discuss the definition, pathophysiology, clinical approach, and management of neurogenic orthostatic hypotension.

Clinical, Endoscopic and Pathogical Characteristics of Early-Onset Colorectal Cancer in Vietnamese

  • Quach, Duc Trong;Nguyen, Oanh Thuy
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.5
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    • pp.1767-1770
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    • 2012
  • Background: The Asia Pacific consensus for colorectal cancer (CRC) recommends that screening programs should begin by the age of 50. However, there have been reports about increasing incidence of CRC at a younger age (i.e. early-onset CRC). Little is known about the features of early-onset CRC in the Vietnamese population. Aim: To describe the clinical, endoscopic and pathological characteristics of early-onset CRC in Vietnamese. Method: A prospective, cross-sectional study was conducted at the University Medical Center from March 2009 to March 2011. All patients with definite pathological diagnosis of CRC were recruited. The early-onset CRC group were analyzed in comparison with the late-onset (i.e. ${\geq}$ 50-year-old) CRC group. Results: The rate of early-onset CRC was 28% (112/400) with a male-to-female ratio of 1.3. Some 22.3% (25/112) of the patients only experienced abdominal pain and/or change in bowel habit without alarming symptoms, 42.9% (48/112) considering their symptoms intermittent. The rate of familial history of CRC in early-onset group was significantly higher that of the late-onset group (21.4% versus 7.6%, p<0.001). The distribution of CRC lesions in rectum, distal and proximal colon were 51.8% (58/112), 26.8% (30/112) and 21.4% (24/112), respectively; which was not different from that in the late-onset group (${\chi}2$, p = 0.29). The rates for poorly differentiated tumors were also not significantly different between the two groups: 12.4% (14/112) versus 8.3% (24/288) (${\chi}2$, p = 0.25). Conclusion: A high proportion of CRC in Viet Nam appear at an earlier age than that recommended for screening by the Asia Pacific consensus. Family history was a risk factor of early-onset CRC. Diagnosis of early-onset CRC needs more attention because of the lack of alarming symptoms and their intermittent patterns as described by the patients.