• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.14 no.8
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• pp.863-870
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• 2003

The digital transmission system entered in a RF region as digital system use IC chips of the speeder edge rate and clock speed nowadays. Optical path really was used in order to obtain the more capacity. In this paper, we described importance of electrical interconnect to get the signal integrity in optical module by simulation and experiment. 12 channel${\times}$2.5 G/ps optical parallel transmitter modules were manufactured by two different method ; access lines with microstrip and stripline type. We have clearly shown that the optical module adopting microstrip type with S$\sub$11/ $\geq$ -10 dB presents distortion but the optical module adopting stripline type with S$\sub$11/ $\leq$ : 15 dB obtains eye opening in 2.5 Gbis optical eye pattern response.

• Journal of Ginseng Research
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• v.39 no.2
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• pp.125-134
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• 2015

Background: Black ginseng (Ginseng Radix nigra, BG) refers to the ginseng steamed for nine times and fine roots (hairy roots) of that is called fine black ginseng (FBG). It is known that the content of saponin of FBG is higher than that of BG. Therefore, in this study, we examined antitumor effects against MCF-7 breast cancer cells to target the FBG extract and its main component, ginsenoside Rg5 (Rg5). Methods: Action mechanism was determined by MTT assay, cell cycle assay and western blot analysis. Results: The results from MTT assay showed that MCF-7 cell proliferation was inhibited by Rg5 treatment for 24, 48 and 72 h in a dose-dependent manner. Rg5 at different concentrations (0, 25, 50 and $100{\mu}M$), induced cell cycle arrest in G0/G1 phase through regulation of cell cycle-related proteins in MCF-7 cells. As shown in the results from western blot analysis, Rg5 increased expression of p53, $p21^{WAF1/CIP1}$ and $p15^{INK4B}$ and decreased expression of Cyclin D1, Cyclin E2 and CDK4. Expression of apoptosiserelated proteins including Bax, PARP and Cytochrome c was also regulated by Rg5. These results indicate that Rg5 stimulated cell apoptosis and cell cycle arrest at G0/G1 phase via regulation of cell cycle-associated proteins in MCF-7 cells. Conclusion: Rg5 promotes breast cancer cell apoptosis in a multi-path manner with higher potency compared to 20(S)-ginsenoside Rg3 (Rg3) in MCF-7 (HER2/ER+) and MDA-MB-453 (HER2+/ER) human breast cancer cell lines, and this suggests that Rg5 might be an effective natural new material in improving breast cancer.

• International Journal of Advanced Culture Technology
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• v.6 no.1
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• pp.42-49
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• 2018

In this study, we tried to reveal the state of stillness of Cho Ji-Hoon's poem "Silent Night 1" as a healing modifier. The language of poem is synaptically linked to the calmness emotion of the human body, seeking a principle that leads to a state of healing. Therefore, this study was carried out for the purpose of applying the principle to literary therapy program. The silent signal embedded in the poem is encoded into the signals of the sound as it is synapsed to the human body. Encoding of auditory nerves by poem lines is like a Morse code that word and word leave in the human body. The action potential of the auditory nerve is further activated by the potential difference between the word and the word represented by the neural network, such as a Morse code, which is accessed to the human body by such a path. There is worked as amplified potential difference between the words perceived by a sound which is synapsed to the human body and by a silence which is synapsed to the human body. The phenomenon of the words approaching the human body and setting the absence of sound and amplifying the sound is because the words amplifies the Morse codes in the human neural network. At this time, the signals overlap each other. Thereby this poem is increasing the amplitude of the sound. This overlapping of auditory signals appears and amplifies the catharsis. If this Cho Ji-Hoon Poem's principle is applied to literary therapy program in the future, more effective treatment will be done.

• The Journal of Information Technology
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• v.5 no.4
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• pp.1-8
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• 2002

This thesis is about power line communication(PLC) over the low voltage grid. The main advantage with power line communication is the use of an existing infrastructure. The PLC channel can be modeled as having multi-path propagation with frequency-selective fading, typical power lines exhibit signal attenuation increasing with length and frequency. OFDM(Orthogonal Frequency Division Multiplexing) is a modulation technique where multiple low data rate carriers are combined by a transmitter to form a composite high data rate transmission. To implement the multiple carrier scheme using a bank of parallel modulators would not be very efficient in analog hardware. Each carrier in an OFDM is a sinusoid with a frequency that is an integer multiple of a base or fundamental sinusoid frequency. Therefore, each carrier is a like a Fourier series component of the composite signal. In fact, it will be shown later that an OFDM signal is created in the frequency domain, and then transformed into the time domain via the Discrete Fourier Transform(DFT).

• The Journal of Information Technology
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• v.6 no.2
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• pp.1-8
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• 2003

This paper is about power line communication(PLC) over the low power voltage grid. The main advantage with power line communication is the use of an existing infrastructure. The PLC channel can be modeled as having multi-path propagation with frequency-selective fading, typical power lines exhibit signal attenuation increasing with length and frequency. OFDM(Orthogonal Frequency Division Multiplexing) is a modulation technique where multiple low data rate carriers are combined by a transmitter to form a composite high data rate transmission. To implement the multiple carrier scheme using a bank of parallel modulators would not be very efficient in analog hardware. Each carrier in an OFDM is a sinusoid with a frequency that is an integer multiple of a base or fundamental sinusoid frequency. Therefore, each carrier is a like a Fourier series component of the composite signal. In fact, it will be shown later that an OFDM signal is created in the frequency domain, and then transformed into the time domain via the Discrete Fourier Transform(DFT).

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.22 no.9
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• pp.82-87
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• 2008

Faster, safer and cheaper mailing of the postal matter is essential for surviving in the competitive market of home-delivery service. In the past, the domestic delivery business has been nu by only a few number of companies. But more and more number of companies including medium size ones are participating in the business, and the competition is getting severe. This paper proposes a method to select the optimal location of mail distribution centers that minimally connect the local mail centers of some major cities in Korea using the Steiner Tree theory, which is about connecting a finite number of points with a minimal length of paths and has been used in the distribution system optimization and optimal routing of the transmission lines of the electric power system. By using Steiner Tree theory in finding the best location of the postal delivery hub, we may expect the reduction of transportation cost and the increase of profit, resulting in acquiring the superior position in the competitive delivery business. It is expected that we may use the Steiner Tree theory in finding the best location of the electric power substation for the nott higher EHV(extreme high voltage) transmission network.

• Proceedings of the KSRS Conference
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• 2002.10a
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• pp.506-506
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• 2002

S. Korean Government has accelerating its efforts to enhance the quality of the drinking water. The Ministry of Environment has declared the law of securing water-pollutant buffering zone to minimize the inflow of the point and nonpoint sources into the drinking water sources. As a first phase of installing nationa-wide water-pollutant buffering zone, approximately 300km buffering zone has been delineated along the South and North Han river, the major drinking water sources for the capital area of S. Korea, which has the population of more than 12 millions. The buffering zone has the width of 1,000 meter for the special protection area, and 500 meter for the remaining area from both ends of the river. The major works have been done in three stages. Firstly, the boundaries lines of the buffering zone was delineated on the digital topographic maps. Secondly, the maps were overlayed with the cadastral maps to identify individual land parcels, the street address of the major pollutant discharging facilities, and all different types of pollutants including livestocks. Thirdly, the field work has been done as a verification. Once the buffering zone was generated, all the information for the buffering gone were created or imported from other government agencies including official land price, details of the major manufacturing facilities discharging considerable amount of pollutants, major motels and resorts, not to mention of restaurants, etc. Also, major livestock houses were located to identify the path of the pollutant inflow to the drinking water source. Further works need to be continued such as purchasing private lands within the buffering zone and change the land use in the efforts to decrease the pollutant amount and to provide more environmentally friendly space. Also, high resolution satellite imagery should be utilized in the near future as a cost-effective data source to update all the landuse activities within buffering zone.

• International Journal of Oral Biology
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• v.43 no.4
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• pp.223-230
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• 2018

Exosomes are Nano-sized lipid vesicles secreted from mammalian cells containing diverse cellular materials such as proteins, lipids, and nucleotides. Multiple lines of evidence indicate that in saliva, exosomes and their contents such as microRNAs (miRNAs) mediate numerous cellular responses upon delivery to recipient cells. The objective of this study was to characterize the different expression profile of exosomal miRNAs in saliva samples, periodically isolated from a single periodontitis patient. Unstimulated saliva was collected from a single patient over time periods for managing periodontitis. MicroRNAs extracted from each phase were investigated for the expression of exosomal miRNAs. Salivary exosomal miRNAs were analyzed using Affymetrix miRNA arrays and prediction of target genes and pathways for its different expression performed using DIANA-mirPath, a web-based, computational tool. Following the delivery of miRNA mimics (hsa-miR-4487, -4532, and -7108-5p) into human gingival fibroblasts, the expression of pro-inflammatory cytokines and activation of the MAPK pathway were evaluated through RT-PCR and western blotting. In each phase, 13 and 43 miRNAs were found to be differently expressed $({\mid}FC{\mid}{\geq}2)$. Among these, hsa-miR-4487 $({\mid}FC{\mid}=9.292005)$ and has-miR-4532 $({\mid}FC{\mid}=18.322697)$ were highly up-regulated in the clinically severe phase, whereas hsa-miR-7108-5p $({\mid}FC{\mid}=12.20601)$ was strongly up-regulated in the clinically mild phase. In addition, the overexpression of miRNA mimics in human gingival fibroblasts resulted in a significant induction of IL-6 mRNA expression and p38 phosphorylation. The findings of this study established alterations in salivary exosomal miRNAs which are dependent on the severity of periodontitis and may act as potential candidates for the treatment of oral inflammatory diseases.

• The Journal of Engineering Geology
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• v.30 no.4
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• pp.525-539
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• 2020

A site containing buried solid waste and treated water and oil storage containers from a leather manufacturing plant was studied through soil and groundwater pollution and electrical resistivity surveys with the aim of identifying areas polluted by leachate generated by landfilling with leather waste and leakage wastewater. It was found that TPH and Zn exceeded environmental standards for soil pollution and, for leachate and groundwater, Cr(VI) concentrations exceeded standard levels for groundwater quality. An electrical resistivity survey was used to elucidate soil and groundwater pollution characteristics and diffusion pathways. Ten survey lines were set up with an electrode spacing of 5 m in a dipole-dipole array. The hydraulic characteristics of soil determined by groundwater contamination surveys matched well the low-resistivity-anomaly zones. Electrical resistivity surveys of areas containing contaminated soil and groundwater that have irregular strata due to waste reclamation are thus useful in highlighting vertical and horizontal pollutant diffusion pathways and in monitoring contaminated and potentially contaminated areas.

• Geophysics and Geophysical Exploration
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• v.8 no.4
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• pp.262-269
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• 2005

Since the buried cultural relics are three-dimensional (3-D) objects in nature, 3-D survey is more preferable in archeological exploration. 3-D Ground Penetrating Radar (GPR) survey based on very dense data in principle, however, might need much higher cost and longer time of exploration than other geophysical methods commonly used for the archeological exploration, such as magnetic and electromagnetic methods. We developed a small-scale continuous data acquisition system which consists of two sets of GPR antennas and the precise positioning device tracking the moving-path of GPR antenna automatically and continuously. Since the high cost of field work may be partly attributed to establishing many profile lines, we adopted a concept of data acquisition at arbitrary locations not along the pre-established profile lines. Besides this hardware system, we also developed several software packages in order to effectively process and visualize the 3-D data obtained by the developed system and the data acquisition concept. Using the developed system, we performed 3-D GPR survey to investigate the possible historical remains of Baekje Kingdom at Buyeo city, South Korea, prior to the excavation. Owing to the newly devised system, we could obtain 3-D GPR data of this survey area having areal extent over about $17,000m^2$ within only six-hours field work. Although the GPR data were obtained at random locations not along the pre-established profile lines, we could obtain high-resolution 3-D images showing many distinctive anomalies, which could be interpreted as old agricultural lands, waterways, and artificial structures or remains. This cast: history led us to the conclusion that 3-D GPR method is very useful not only to examine a small anomalous area but also to investigate the wider region of the archeological interests.