• Journal of the Society of Cosmetic Scientists of Korea
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• v.29 no.2 s.43
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• pp.131-147
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• 2003

In the 21st century, the development of cosmetics is led to pursue the high functionality of cosmetics with excellent effectiveness and safety. As Cosmetic Act took effect in 2000, functional cosmetics is provided in the law. As a result, the research and development of functional cosmetics has continually increased, and the number of patent applications in functional cosmetics has also rapidly increased as a plan for preoccupying in the functional cosmetics age. Now, the cosmetic industry has a great interest in developing anti-wrinkle cosmetics among functional cosmetics, because women's desire for having young resilient skin has increased since Korea entered an aging society thanks to the advanced medical technology. The patent application trends of anti-wrinkle cosmetics at home since 2000 particularly show the rapid increase in the applications in natural plant extracts. It may be because Korean consumers preference of vegetable cosmetics has resulted in the development of raw materials based on the traditional medicine. As for the existing preparation such as Retinoid or Ascorbic acid, the patent application itself will be an essential technical element in the future because patent applications are filed in the field of a preparation of cosmetics for stabilizing ingredients, reducing skin irritability or promoting absorbance, and in the field of cosmetic formulation technology. As there are many studies on the causes of skin wrinkles, it is expected that new raw materials of cosmetics can be developed due to new mechanisms, and that the number of patent applications in new technologies will increase due to a change in the thought of cosmetics accompanied by the integration of cosmetics with biotechnology using Genetic Engineering, including the practical application of the medicine previously used far treating skin diseases to an anti-wrinkle agent and the mass production of active ingredients of cosmetics.

• Journal of Veterinary Clinics
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• v.33 no.4
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• pp.221-224
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• 2016

An 8 month-old male Maltese (weighing 2.0 kg) was referred with loud heart murmur at routine physical exam in local animal clinic. Electrocardiogram found left ventricular hypertrophy pattern (4.5 mV R-wave). Diagnostic imaging studies revealed the elongation of left ventricle (LV) with classic triple bumps on the main pulmonary artery, aorta and left atrium on the ventrodorsal view of radiograph. Echocardiography revealed patent ductus arteriosus (PDA) duct and continuous turbulent shunt flow (maximal velocity 4.83 m/s) between the aorta and pulmonary artery with left to right direction. The PDA in this dog was successfully closed through femoral vein (transvenous approach) using a 5 mm Amplatz$^{(R)}$ Canine Duct Occluder. To the best of author's knowledge, this is the first case of PDA occlusion treated with Amplatz Canine Duct Occluder through femoral vein.

• Korean Journal of Pharmacognosy
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• v.34 no.1 s.132
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• pp.1-5
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• 2003

'Cheong Wi Dan (淸胃丹)' is a Chinese patent preparation which has been used for various diseases in Korea. This preparation consists of 19 powder crude drugs. Cheong Wi Dan is used for catarrh of the gastrointestines, indigestion, a pain in the chest and nausea. The microscopic method is ve교 useful to identify individual gradients in powdery mixture because it requires only a small amount of specimens. In this study, it is demonstrated that the microscopic method is very useful for the identification of 19 crude drug ingredients included in Cheong Wi Dan.

• Journal of Chest Surgery
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• v.43 no.1
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• pp.89-91
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• 2010

Aortic and pulmonary valve endocarditis with patent ductus arteriosus (PDA) is uncommon in adult. A 60-year-old woman was diagnosed with aortic and pulmonary valve endocarditis and PDA. We describe our surgical experience for treating PDA with double valve endocarditis.

• Journal of Oriental Neuropsychiatry
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• v.34 no.3
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• pp.247-257
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• 2023

Objectives: To analyze the trend of Korean patents of natural product extracts for depression. This study also aimed to enhance the development and application of natural product extracts for depression in Korean herbal medicine. Methods: We searched the Korea Intellectual Property Rights Information Service and Science ON to collect Korean patent data of natural product extracts for depression. Two authors independently screened and assessed full texts of screened patents for eligibility. Included patents were analyzed both quantitatively and qualitatively. Results: A total of 62 patents from 2002 to December 2021 were included for analysis. The number of patents has constantly increased since 2002. Glycyrrhiza uralensis Fischer, Perilla frutescens Britton var. acuta Kudo, Zizyphus jujuba Miller var. inermis Rehder were frequently used among 62 patents. Alcohol extraction was mostly used, followed by water extraction and ethyl extraction regarding extract methods. Eight patents were herbal medicine used for treating depression in Korean Medicine. Conclusions: Various Korean herbal medicine and minerals were used as natural-products for treating depression. These results provide fundamental data that can be used for inventing new patents using Korean herbal medicine, developing new natural product extracts for depression, and extending the range of application of these products in clinical setting.

• Korean Journal of Veterinary Service
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• v.47 no.1
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• pp.55-59
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• 2024

A 4-year-old, spayed female German Shepherd dog (GSD) weighing 22.4 kg was referred to Chungnam National University Veterinary Medicine Teaching Hospital with the chief complaint of a cardiac murmur. A continuous murmur was detected at the left basilar region upon auscultation. In the thoracic radiographs, slight bulging of the aorta, the main pulmonary artery, and the left atrium were observed. Echocardiography revealed continuous turbulent flow directed from the main pulmonary artery towards the pulmonary valve and consistently within the main pulmonary artery. Based on all the results, a diagnosis of type II A patent ductus arteriosus (PDA) was made, and plans were established to treat it with transcatheter occlusion. Transcatheter occlusion was performed using a vascular plug and successfully deployed at the PDA. The patient did not exhibit any complications. GSDs are relatively less common compared to small-breed dogs in South Korea. Considering that GSDs are predisposed to PDA, it is crucial to periodically assess the presence of PDA through auscultation and echocardiography, even in the absence of clinical signs. Transcatheter occlusion using a vascular plug can be an option for treatment and can yield favorable outcomes.

• The Journal of Fisheries Business Administration
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• v.45 no.2
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• pp.1-13
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• 2014

This study analyzes patent trends regarding farming-related technologies such as breeding or nursery technology, production systems, and new cultivation methods in order to provide objective patent information about the trends of R&D on marine products' proliferation or farming. Presently, in Korea, we try to secure marine living resources through the formation of artificial resources instead of environmental improvement policy or resource management policy. However, this is not about eliminating the causes of marine environment destruction but just the policy for improvement, so it is needed to revise the related policy with more ultimate measures. And it is necessary to develop technology that can secure the rights by integrating patent application strategies from the stage of R&D for medicine that can be utilized in chief farming countries and provide intensive support for the research centering around strategic varieties for farming in each region as well as strategic national farming varieties afterwards. Also, the analysis shows that it is urgent to make applications overseas based on domestic applications in order to develop technology that can be commercialized in not just Korean but overseas market as well.

• Korean Journal of Plant Resources
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• v.30 no.4
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• pp.466-474
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• 2017

The Omija (Schizandra chinensis Baillon) is a fruit native to northeast Asia that is cultivated in South Korea and China. Using 1,938 valid patents of 6 group countries, we analyzed the patent trend based on year, countries, applicants, and technology. The technologies are categorized the 10 sub-technologies such as medicine, quasi-drugs, food, feed, cosmetics, cultivation, genome, manufacture, preprocessing, and etc. The technology level and competitiveness are analyzed using patent index such as cites per patent, patent impact index, patent family size and technology strength. In Korea, patent number rapidly increasing and individual technical level is lower than other countries. However, overall technical competitiveness is estimated high due to multiple patents. We suggest that cosmetics and cultivation fields are most likely to be developed in future omiza technology development in Korea. Our study will provides to the information of technical trend to support performing of new projects for Omija plant.

• Korean Journal of Oriental Medicine
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• v.12 no.3 s.18
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• pp.17-29
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• 2006

The Syndrome Differentiation(辨證) means to make diagnosises and to classify symptoms based oriental medicine theory. Questionnaires and clinical decision support system would assist the doctor checks up symptoms of a patient. We analyze about domestic and foreign patents and papers of these diagnosis tools and catch the trend. In patents, the system examines by telemedicine and offers medical information and prescriptions to patient. Papers was itemized fields ; theory, methods of analysis, clinical application, questionnaire, clinical decision support system. The results of this research can be applied to develop the high-quality tool to support syndrome differentiation.

• Journal of Cardiovascular Imaging
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• v.30 no.4
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• pp.328-329
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• 2022