• JSTS:Journal of Semiconductor Technology and Science
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• v.9 no.2
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• pp.117-123
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• 2009

$Pb_{x}Cd_{1-x}S$ films are prepared in the composition range of 0.05${\leq}x{\leq}$0.25, using a chemical bath deposition growth technique under optimum conditions amide at realizing good photo response. The x-ray diffraction results show that the films are of PbS-CdS composite with individual CdS and PbS planes. The films exhibit two direct band gaps, 2.4 eV attributed to CdS, while the other varies continuously from 2.4 eV to 1.3 eV. The films surface morphology is smooth with crystallite, whose grain size increases with increasing mole fraction (x). The decrease in band gap with increase in lead concentration suggests inter-metallic compound of PbS (Eg=0.41 eV) with CdS (Eg=2.4 eV)

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.191.1-191.1
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• 2014

Crystallization has become the most popular technique for the separation of enantiomers since the Pasteur's discovery. To investigate mechanism of crystallization of chiral molecules, it is necessary to study self-assembled structures on two-dimensional surface. Here, we have studied two-dimensional self-assembled structures of an unnatural amino acid, (S)-${\beta}$-methyl naphthalen-1-${\gamma}$-aminobutyric acid (${\gamma}^2$-1-naphthylalanine) on Au(111) surface at 150 K using scanning tunneling microscopy (STM). At initial stage, we found two chiral honeycomb structures which are counter-clockwise and clockwise configurations in one domain. The molecules are arranged around molecular vacancies, dark hole. By further increasing the amounts of adsorbed ${\gamma}^2$-1-naphthylalanine, a well-ordered square packed structure was observed. In addition, we found the other structure that molecules were trapped in the pore of the hexagonal molecular assembly.

• Journal of Biomedical Engineering Research
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• v.11 no.2
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• pp.269-276
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• 1990

This study describes the battery functional test in order to explore vestibular oculomotor system. These tests are the following : a) acceleration test by using a pseudorandom stimulus. b) caloric test by considering both the constant temperature variation in the semicircular canals for a short time and the only head movement, to the fore and the back, for the ear ir- rigation, which gave us two types of stimulus (cold and warm) according to the only head position. c) optokinetic test by continuous constant velocity displacement of a large image fill- ing the entire subject's visual field. With relation to the clinical practices, some results of research programs which are at present in progress are presented.

• Journal of Biomedical Engineering Research
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• v.10 no.2
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• pp.125-130
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• 1989

In the present study, we described a test to explore the function of optokinetic system which subjected to a full visual field stimulation using two different stimulus images patterns. Our results were interesting in a point of view that the stimulation image pattern had non- neglisible influence on the optokinetic response and that in a bidimensionnel image such as the randomly distributed spots images pattern the linearity of system was assured upto the stimulus velocity of about 50 deg/sec for normal subject. As for measuring human optokinetic after nystagmus, the regular stripes pattern was rather desirable than the randomly distributed spots pattern in this study.

• The Microorganisms and Industry
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• v.17 no.2
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• pp.12-17
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• 1991

미생물학적 물질변환에 대해서는 인류 초기에서부터 효모를 이용하여 빵, 유제품, 알코올, 음료 등의 생산에 이용하여 왔으며, 주로 농업분야 또는 식품 분야에 국한되어 왔다. 1862년 Pasteur에 의해 bacterium xylinum의 순수 배양균주를 사용하여 알코올로부터 초산을 만드는데 응용한 것이 본격적인 시발점으로 보아 무방하겠다. 그 후 acetobacter aceti에 의한 포도당으로부터 gluconic acid 생산과 acetobacter sp.에서의 sorbitol로부터 sorbose 생산 등이 이루어졌고 정통적인 유기합성 방법에 의해 쉽게 만들 수 없는 반응들에 응용되기 시작하였다. 인류 초기의 혼합배양에 의한 물질변환에의 응용과는 달리 순수배양으로 미생물, 식물세포, 혹은 정제된 효소들에 의해 반응이 이루어지게 되었고 순수한 특정 물질에 대한 새로운 순수물질로의 선별적인 수식도 가능해지게 되었다. 특히 발효와 bioconversion의 차이는 racemates의 분리, 비슷한 반응성을 갖는 여러 기들로부터 특정기능을 갖는 기만의 선별적인 수식, 입체 이성체(chiral center)의 제작, 특정 비활성화된 탄소의 기능 등이 bioconversion에서만 수행할 수 있는 독특한 영역으로서 정밀화학분야, energy 분야, 환경오염분야에서의 특히 미래의 관심 기술로 대두되고 있다.

• Journal of Dairy Science and Biotechnology
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• v.38 no.4
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• pp.230-236
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• 2020

Heat treatment is a fundamental processing technology in the dairy industry. The main purpose of heat treatment is to destroy pathogenic and spoilage promoting microorganisms to ensure milk safety and shelf life. Despite the development of alternative technologies, such as high-pressure processing and pulse field technology for microbial destruction, heat treatment is widely used in the dairy industry and in other food processes to destroy microorganisms. Heat treatment has contributed greatly to the success of food preservation since Pasteur's early discovery that heat treatment of wine and beer could prevent their deterioration, and since the introduction of milk pasteurization in the 1890s. In Korea, food labeling standards do not stratify heat treatments into low temperature, high temperature, and ultra-high temperature methods. Most milk is produced in Korea by pasteurization, with extended shelf life (ESL : 125--140℃ / 1-10 s). Classification based on temperature (i.e. low, high, and ultra-high), is meaningless.

• Journal of Microbiology and Biotechnology
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• v.32 no.1
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• pp.1-5
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• 2022

Diagnostics, vaccines, and drugs are indispensable tools and control measures employed to overcome infectious diseases such as coronavirus disease 2019 (COVID-19). Diagnostic tools based on RT-PCR were developed early in the COVID-19 pandemic and were urgently required for quarantine (testing, tracing and isolation). Vaccines such as mRNA vaccines and virus-vectored vaccines were also successfully developed using new platform technologies within one year after identifying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as the causative agent of COVID-19. Drug development has been conducted in various ways including drug repurposing, convalescent plasma therapy, and monoclonal antibody development. Among the above efforts, this review examines COVID-19 drug development along with the related and upcoming challenges.

• BMB Reports
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• v.56 no.6
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• pp.326-334
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• 2023

Antibiotic resistance (AR) is a silent pandemic that kills millions worldwide. Although the development of new therapeutic agents against antibiotic resistance is in urgent demand, this has presented a great challenge, especially for Gram-negative bacteria that have inherent drug-resistance mediated by impermeable outer membranes and multidrug efflux pumps that actively extrude various drugs from the bacteria. For the last two decades, multidrug efflux pumps, including AcrAB-TolC, the most clinically important efflux pump in Gram-negative bacteria, have drawn great attention as strategic targets for re-sensitizing bacteria to the existing antibiotics. This article aims to provide a concise overview of the AcrAB-TolC operational mechanism, reviewing its architecture and substrate specificity, as well as the recent development of AcrAB-TolC inhibitors.

• Food Science and Preservation
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• v.15 no.2
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• pp.306-310
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• 2008

This study investigated the effects of 3 different strains of my yeast (Saccharomyces cerevisiae Montrachet (UCD #522), S. bayanus Pasteur Champagne (UCD #595), and S. cerevisiae Epernay (CEG) and two grape varieties (Tamnara and M.B.A) on the quality of red wines. During fermentation, sugar content decreased and alcohol content increased Addition of my yeast increased fermentation speed for both grape varieties. Sensory quality tests and tests with an electronic tongue showed that red wine made from M.B.A grapes was superior to that made from Tamnara grapes and that red wine made without the addition of my yeast was better than that made by using dry yeast.

• Journal of Dairy Science and Biotechnology
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• v.27 no.1
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• pp.13-18
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• 2009

We confirmed methane production and reduction of pollution during anaerobic digestion of milk waste and analyzed the economic potential of using milk waste as a renewable energy source. The milk waste sludge was obtained from the Pasteur milk factory and processed by anaerobic digestion to produce methane. The methane production from two completely mixed tank reactors with an effective capacity of 6 ${\ell}$, 15 days of hydraulic retention time (HRT), and a mid-temperature of $35^{\circ}C$ averaged 4.11 ${\ell}$/day. The total chemical oxygen demand (TCOD) during production decreased from an initial 31,416 mg/${\ell}$ to 13,500 mg/${\ell}$, showing a maximum TCOD removal efficiency of 60%. When HRT was reduced to 12 days, methane production increased by 44% under a high-temperature condition of $55^{\circ}C$. An economic analysis based on these results was applied to a Korean milk factory of typical size and demonstrated that the installation of an anaerobic digester could provide sufficient economic profit.