• 유체기계공업학회:학술대회논문집
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• 2006.08a
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• pp.341-344
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• 2006

In this analytical study on the engine coolant flow of a heavy-duty diesel engine with 4 valves and linear-type 8 liter 6 cylinders, the characteristics of pressure drop and engine cooling performance with the additional coolant passages between cylinder blocks have been investigated. Since the most part of pressure drop is caused by the coolant flow passages inside a cylinder head and cylinder blocks for this type of heavy-duty diesel engines, the advantage of pressure drop is just 2.6% and the characteristics of heat transfer and the distribution of coolant velocities in the head part show little differences in case of additional coolant passages. Thus the coolant flow passages between cylinder blocks make little contribution on the cooling performance of heavy-duty diesel engines

• Journal of The Korean Astronomical Society
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• v.54 no.3
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• pp.103-112
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• 2021

The intracluster medium (ICM) is expected to experience on average about three passages of weak shocks with low sonic Mach numbers, M ≲ 3, during the formation of galaxy clusters. Both protons and electrons could be accelerated to become high energy cosmic rays (CRs) at such ICM shocks via diffusive shock acceleration (DSA). We examine the effects of DSA by multiple shocks on the spectrum of accelerated CRs by including in situ injection/acceleration at each shock, followed by repeated re-acceleration at successive shocks in the test-particle regime. For simplicity, the accelerated particles are assumed to undergo adiabatic decompression without energy loss and escape from the system, before they encounter subsequent shocks. We show that in general the CR spectrum is flattened by multiple shock passages, compared to a single episode of DSA, and that the acceleration efficiency increases with successive shock passages. However, the decompression due to the expansion of shocks into the cluster outskirts may reduce the amplification and flattening of the CR spectrum by multiple shock passages. The final CR spectrum behind the last shock is determined by the accumulated effects of repeated re-acceleration by all previous shocks, but it is relatively insensitive to the ordering of the shock Mach numbers. Thus multiple passages of shocks may cause the slope of the CR spectrum to deviate from the canonical DSA power-law slope of the current shock.

• Tissue Engineering and Regenerative Medicine
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• v.15 no.6
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• pp.771-779
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• 2018

BACKGROUND: Mesenchymal stromal cells (MSCs) are multipotent stem cells that can differentiate into several cell types. In addition, many studies have shown that MSCs modulate the immune response. However, little information is currently available regarding the maintenance of immunomodulatory characteristics of MSCs through passages. Therefore, we investigated and compared cytokine and gene expression levels from adipose (AD) and bone marrow (BM)-derived MSCs relevant to immune modulation from early to late passages. METHODS: MSC immunophenotype, growth characteristics, cytokine expressions, and gene expressions were analyzed. RESULTS: AD-MSCs and BM-MSCs had similar cell morphologies and surface marker expressions from passage 4 to passage 10. Cytokines secreted by AD-MSCs and BM-MSCs were similar from early to late passages. AD-MSCs and BM-MSCs showed similar immunomodulatory properties in terms of cytokine secretion levels. However, the gene expressions of tumor necrosis factor-stimulated gene (TSG)-6 and human leukocyte antigen (HLA)-G were decreased and gene expressions of galectin-1 and -3 were increased in both AD- and BM-MSCs with repeated passages. CONCLUSION: Our study showed that the immunophenotype and expression of immunomodulation-related cytokines of AD-MSCs and BM-MSCs immunomodulation through the passages were not significantly different, even though the gene expressions of both MSCs were different.

• Journal of Ecology and Environment
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• v.38 no.2
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• pp.163-173
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• 2015

The occurrence of wild boars (Sus scrofa Linnaeus) and reports of wildlife-vehicle conflicts (i.e., road-kill) involving them have increased in natural forest regions of Korea. In the past few decades, many wildlife passages have been constructed to reduce vehicle collisions involving wildlife species. However, few studies have assessed the habitat suitability of target wildlife species when locating the construction sites of wildlife passages. Target species rarely use wildlife passages if built in an inappropriate location. Therefore, a quantitative habitat model is required to find suitable sites for wildlife passages that can connect the fragmented forest patches of wildlife habitats in Korea. In this study, the wild boar was selected as the target species, and six environmental variables (percentage of Quercus forest, slope aspect, distance to roads, water accessibility, forest stand age and density) were measured. The habitat model for wild boars was developed with a Delphi survey, and habitat suitability maps were delineated for the provinces of Gangwon-do and Jeollanam-do. In this study, 298 and 64 boars were observed in Gangwon-do and Jeollanam-do, respectively. Observations of wild boars derived from the second nationwide natural environmental survey were used to evaluate the habitat model. Habitat suitability maps that superimposed existing road networks suggested that wild boar habitats were severely fragmented in both provinces, particularly in Gangwon-do. To connect the fragmented habitats and prevent wildlife-vehicle collisions, this study proposes 11 and 5 wildlife passage sites in Gangwon-do and Jeollanam-do, respectively.

• Journal of computational fluids engineering
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• v.19 no.4
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• pp.86-93
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• 2014

Increased demand of power-transformer's capacity inevitably results in an excessive temperature rise of transformer components, which in turn requires improved radiator design. In this paper, numerical simulation of the cooling performance of an ONAN-type (Oil Natural Air Natural) radiator surrounded by air was performed by using CFX. The natural convection of the air was treated with the full-model. The present parametric study considers variation of important variables that are expected to affect the cooling performance. We changed the pattern and cross-sectional area of flow passages, the fin interval, the flow rate of oil and shape of flow passages. Results show that the area of flow passage, the fin interval, the flow rate of oil and shape of flow passages considerably affect the cooling performance whereas the pattern of flow passages is not so much influential. We also found that for the case of the fin interval smaller than the basic design, the temperature drop decreases while a larger interval gives almost unchanged temperature drop, indicating that the basic design is optimal. Further, as the flow rate of oil increases, the temperature drop slowly decreases as expected. On the other hand, when the shape of flow passages are changed, temperature drop is increased, indicating that the cooling performance is enhanced thereupon.

• Proceedings of the KSAR Conference
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• 2001.03a
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• pp.64-64
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• 2001

To facilitate the widespread application of somatic cell cloning, improvements in blastocyst production efficiency and subsequent fetal viability are required. Area where technical improvements are needed include donor cell treatments, starvation and passage numbers. This study was carried out to investigate the effect of serum-starvation and passage on the development of ear skin fibroblast cells cloned embryos. A skin biopsy was obtained from the ear of a 2-year-old Korean Hanwoo female. The cells were cultured in 10% FBS＋DMEM up to 2-3 months(up to 10 passages) and then used. In Experiment 1, the Korean bovine Ear Skin Fibroblast cells (KbESF) were either serum starved (culture in 0.05% FBS＋DMEM) or serum fed (10% FBS＋DMEM) for 4-7 days Prior to NT In Experiment 2, the KbESF cells used for nuclear transfer in these experiments were from passages 2 to 10. The development of 208 nuclear transfer (NT) embryos reconstructed from either serum starved or serum fed ear skin fibroblast was assessed. NT embryos reconstructed from serum starved and serum fed cells showed the same developmental rate (cleavage 80.16 vs. 85.37%; blastocyst 20.63 vs. 19,51%). The development of 590 nuclear transfer (NT) embryos reconstructed from passage 2 to 10 was assessed. We observed the same developmental rates for embryos derived from later Passages as compared with those embryos from early passages(blastocyst from 16.69 to 27.91%, average 20.17%). There was no significant difference between serum-fed and serum-starved donor cells. We observed no difference in developmental rates for embryos derived from 2 to 10 passages. These data show that prolonged culture and serum starvation does not affects the cloning competence of adult somatic cells.

• Journal of Microbiology and Biotechnology
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• v.22 no.7
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• pp.981-989
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• 2012

This study aimed to evaluate the effects of electroporation on the cell growth, cholesterol removal, and adherence abilities of L. acidophilus BT 1088 and their subsequent passages. The growth of electroporated parent cells increased (P<0.05) by 4.49-21.25% compared with that of the control. This may be attributed to the alteration of cellular membrane. However, growth of first, second, and third passages of treated cells was comparable with that of the control, which may be attributed to the resealing of transient pores on the cellular membrane. Electroporation also increased (P<0.05) assimilation of cholesterol by treated parent cells (>185.40%) and first passage (>21.72%) compared with that of the control. Meanwhile, incorporation of cholesterol into the cellular membrane was also increased (P<0.05) in the treated parent cells (>108.33%) and first passage (>26.67%), accompanied by increased ratio of cholesterol:phospholipids (C:P) in these passages. Such increased ratio was also supported by increased enrichment of cholesterol in the hydrophilic heads, hydrophobic tails, and the interface regions of the membrane phospholipids of both parent and first passage cells compared with that of the control. However, such traits were not inherited by the subsequent second and third passages. Parent cells also showed decreased intestinal adherence ability (P<0.05; decreased by 1.45%) compared with that of the control, without inheritance by subsequent passages of treated cells. Our data suggest that electoporation could be a potential physical treatment to enhance the cholesterol removal ability of lactobacilli that was inherited by the first passage of treated cells without affecting their intestinal adherence ability.

• 한국신재생에너지학회:학술대회논문집
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• 2009.06a
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• pp.624-627
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• 2009

Design of ocean fishways as eco-movement passages for turbine structures, sluice structures and barrages of a environmentally-friendly tidal power system through which fish can pass are suggested. The ocean fishways comprise a plurality of fishways to allow fish to move between the sea-side and the lake-side of the barrages and turbine structures and sluice structures. It is demonstrated that the inventive ocean fishways are cost effective to construct and environmentally-friendly eco-movement passages for fish and benthos to move between sea-side and lake-side without passing through the turbine blades of a tidal power plant in operation.

• Speech Sciences
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• v.3
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• pp.26-37
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• 1998

The Connected Speech Test (CST) was developed to test hearing aid performance using realistic stimuli (Connected speech) presented in a background of noise with a visible speaker. The CST has not been investigated as a measure of speech reading ability using the visual portion of the CST only. Thirty subjects were administered the 48 test lists of the CST using visual presentation mode only. Statistically significant differences were found between the 48 test lists and between the 12 passages of the CST (48 passages divided into 12 groups of 4 lists which were averaged.). No significant differences were found between male and female subjects; however, in all but one case, females scored better than males. No significant differences were found between students in communication disorders and students in other departments. Intra- and inter-subject variability across test lists and passages was high. Suggestions for further research include changing the scoring of the CST to be more contextually based and changing the speaker for the CST.

• Progress in Superconductivity and Cryogenics
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• v.10 no.4
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• pp.33-37
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• 2008

The main objective of this study is to identify the pressure drop characteristics of coolant flow passages of 154kV/1GVA High Temperature Superconducting (HTS) power cable, experimentally. The passages were consisted of two parts, the one is the circular path with spiral ribs in the core to cool the cable conductor layer and the other is annular path with spirally corrugated outer wall to cool the shield layer. Thus the experiments to acquire the pressure drop data were performed with two types of circular spiral tubes and eight types of the concentric annuli in various range of Reynolds number. The pressure drops in the core tubes and the annuli were much higher than those in the tubes with smooth surface. Therefore, modified correlations to present the experimental results in each flow passage were suggested.