• BMB Reports
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• v.29 no.2
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• pp.175-179
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• 1996

Viral surface proteins are known to play an essential role in attachment of the virus particle to the host cell membrane. In case of the hepatitis B virus (HBV) several reports have described potential receptors on the target cell side, but no definite receptor protein has been isolated yet. As for the viral side, it has been suggested that the preS region of the envelope protein, especially the preS1 region, is involved in binding of HBV to the host cell. In this study, preS1 region was recombinantly expressed in the form of a maltose binding protein (MBP) fusion protein and used to identify and visualize the expression of putative HBV receptor(s) on the host cell. Using laser scanned confocal microscopy and by FACS analysis, MBP-preS1 proteins were shown to bind to the human hepatoma cell line HepG2 in a receptor-ligand specific manner. The binding kinetic of MBP-preS1 to its cellular receptor was shown to be temperature and time dependent. In cells permeabilized with Triton X-100 and treated with the fusion protein, a specific staining of the nuclear membrane could be observed. To determine the precise location of the receptor binding site within the preS1 region, several short overlapping peptides from this region were synthesized and used in a competition assay. In this way the receptor binding epitope in preS1 was revealed to be amino acid residues 27 to 51, which is in agreement with previous reports. These results confirm the significance of the preS1 region in virus attachment in general, and suggest an internalization pathway mediated by direct attachment of the viral particle to the target cell membrane.

• Journal of Astronomy and Space Sciences
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• v.37 no.1
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• pp.35-42
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• 2020

Particle-in-cell simulations were performed to understand the interaction of the solar wind with localized magnetic fields on the sunlit surface of the Moon. The results indicated a mini-magnetosphere was formed which had a thin magnetopause with the thickness of the electron skin depth. It was also found that the solar wind penetrated into the cavity of the magnetosphere intermittently rather than in a steady manner. The solar wind that moved around the magnetosphere was observed to hit the surface of the Moon, implying that it may be the cause of the lunar swirl formation on the surface.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.242.1-242.1
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• 2014

The electron cyclotron resonance plasma source with a belt-type magnet assembly (BMA) is designed for effective plasma confinements. For characterizing the plasma source, the plasma parameters are measured by Langmuir probe. However, the plasma parameters and the motion of charged particles near the ECR zone are not easy to diagnostics, because of the high plasma density and temperature. Thus, as an alternative method, the electromagnetic simulation of the plasma source has been performed by using three-dimensional particle-in-cell and Monte Carlo collisional (PIC-MCC) simulation codes. For considering the limitation of simulation resources and time, the periodic boundary condition is applied and the coulomb collision is neglected. In this paper, we present the results of 3D PIC simulations of ECR plasmas with BMA and we compare them with the experimental results.

• Korean Chemical Engineering Research
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• v.54 no.2
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• pp.278-283
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• 2016

In this study, we have for the first time applied fractional precipitation with hydrophilic polymer in order to decrease the particle size of the anticancer agent paclitaxel from plant cell cultures. When compared with the case where no hydrophilic polymer was employed, the addition of hydrophilic polymer in fractional precipitation resulted in a decrease in the size of the paclitaxel precipitate. Among the polymers used, HPMC 2910 was the most effective for inhibition of precipitate growth. A polymer concentration of 0.2% (w/v) obtained the smallest particle size. The particle size was reduced by ~35% compared to control. In addition, the precipitate size was inversely correlated with the absolute value of the zeta potential.

• Korean Journal of Materials Research
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• v.11 no.8
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• pp.703-707
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• 2001

The effects of chromium addition on the catalytic activity of Raney nickel in alkaline fuel cell (AFC) have been studied. When the catalysts are prepared from various contents of chromium, the electrochemical characteristics shows the highest mass activity of 3.588 A/g. Operating temperature and electrolyte concentration of half cell were $80^{\circ}C$ and 6N KOH, respectively. With the addition of chromium, the particle size is diminished from 12.11 $\mu\textrm{m}$ to 11.07 $\mu\textrm{m}$ and the decrease of particle size contributes to the enlargement of the specific surface area from 0.653 $\m^2$/g to 0.685$\m^2$/g. The residual aluminium contents of Raney nickel surface are considerably influenced by the particle size and chromium acts as sintering inhibitor.

• Structural Engineering and Mechanics
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• v.34 no.4
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• pp.525-539
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• 2010

Polymer matrix composites are widely used in many engineering applications as they can be customized to meet a desired performance while not only maintaining low cost but also reducing weight. Polymers can experience viscoelastic-viscoplastic response when subjected to external loadings. Various reinforcements and fillers are added to polymers which bring out more complexity in analyzing the timedependent response. This study formulates an integrated micromechanical model and finite element (FE) analysis for predicting effective viscoelastic-viscoplastic response of polymer based hybrid composites. The studied hybrid system consists of unidirectional short-fiber reinforcements and a matrix system which is composed of solid spherical particle fillers dispersed in a homogeneous polymer constituent. The goal is to predict effective performance of hybrid systems having different compositions and properties of the fiber, particle, and matrix constituents. A combined Schapery's viscoelastic integral model and Valanis's endochronic viscoplastic model is used for the polymer constituent. The particle and fiber constituents are assumed linear elastic. A previously developed micromechanical model of particle reinforced composite is first used to obtain effective mechanical properties of the matrix systems. The effective properties of the matrix are then integrated to a unit-cell model of short-fiber reinforced composites, which is generated using the FE. The effective properties of the matrix are implemented using a user material subroutine in the FE framework. Limited experimental data and analytical solutions available in the literatures are used for comparisons.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.26 no.12
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• pp.50-55
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• 2012

This paper presents an application of optimization method for efficient operation in micro grid. For operational efficiency, the objective function in a diesel generator consists of the fuel cost function similar to the cost functions used for the conventional fossil-fuel generating plants. The wind turbine generator is modeled by the characteristics of variable output. The cost function of fuel cell plant considers the efficiency of fuel cell. Particle swarm optimization(PSO) and sequential quadratic programming(SQP) are used for solving the problem of microgrid system operation. Also, from the results this paper presents the way to attend power markets which can buy and sell power from upper lever grids by connecting a various generation resources to micro grid.

• Proceedings of the Korean Vacuum Society Conference
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• 2012.02a
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• pp.454-454
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• 2012

Magnetron sputtering에서, 영구자석의 자속은 target 표면 가까이에 전자를 구속한다. 구속된 전자는 Ar중성기체와 충돌하여 Ar이온을 발생시킬 수 있으므로, target 근처에서의 플라즈마 밀도를 높여, 자석이 없을 때보다 낮은 압력 또는 낮은 전압에서 방전할 수 있다. 구속 전자가 밀집된 공간에서 sputtering 현상이 주로 발생하기 때문에, planar target을 사용할 경우에는 target이 불균일하게 식각되어 target의 사용효율이 좋지 못하다. 이에 대한 한 가지 대안은 target을 원통형으로 만들어 회전시키는 것이다. Cylindrical target 의 내부에 위치한 영구자석은 고정시키고, target만을 회전시키면 비교적 균일하게 식각되므로 target의 사용효율을 높일 수 있다. 본 연구에서는 기존의 planar target에 대한 Particle-In-Cell Simulation을 Cylindrical target 에 적용시키기 위한 방법을 알아본다. 또한, 개발된 Simulator를 이용하여, Sputtering 조건의 변화에 대한 I-V curve의 변화를 살펴본다.

• Journal of the Optical Society of Korea
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• v.18 no.5
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• pp.429-435
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• 2014

We examined the effective utilization of Particle Swarm Optimization (PSO) to enhance the light absorption performance in thin CuIn1-xGaxSe2 (CIGS) solar cells with dual (top and bottom) gratings. The PSO tuned structure was demonstrated to be capable of achieving high and ultra broadband absorption spectra due to well-spaced and well-defined absorption peaks, which were SPPs and photonic modes induced by the metal and dielectric gratings. For only TM polarization and both polarizations, the fully optimized net absorptions exhibit 85.6% and 78.1%, which correspond to ~35.4% and ~23.5% improvement compared to optimized flat structures, respectively.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.23 no.6
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• pp.778-787
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• 1999

In this study, the autoignition process of liquid fuel, injected into hot and stagnant air in a 2-D axisymmetric confined cylindrical combustor, has been investigated. Eulerian-Lagrangian scheme was adopted to analyze the two-phase flow and combustion. The unsteady conservation equations were used to solve the transition of the gas field. Interactions between two phases were accounted by using the particle source in cell (PSI-Cell) model, which was used for detailed consideration of the finite rates of transports between phases. And infinite conduction model was adopted for the vaporization of droplets. The results have shown that the process of the autoignition consists of heating up of droplets, vaporization, mixing and ignition. The ignition criteria could be determined by the temporal variations of temperature, reaction rate and species mass fraction. And the effects of various parameters on ignition phenomena are examined. These have shown that the increasing the reaction rate and/or the vaporization rate can reduce the ignition delay time.