• Journal of the Korean Magnetic Resonance Society
• /
• v.16 no.1
• /
• pp.46-66
• /
• 2012

Metabolomic studies using human urine have shown that human metabolism is altered by a variety of environmental, cultural, and physiological factors. Comprehensive information about normal human metabolite profiles is necessary for accurate clinical diagnosis of disease and for disease prevention and treatment. In this study, metabolite correlation analyses, using $^1H$ nuclear magnetic resonance (NMR) spectroscopy coupled with multivariate statistics, were performed on human urine to compare metabolic differences based on gender and/or obesity in healthy human subjects. First, we applied partial least squares discriminant analysis to the NMR spectral data set to verify the data's ability to discriminate by gender and obesity. Then, the differences in metabolite-metabolite correlation between male and female, and between normal and high body mass index (obese) subjects were investigated through pairwise correlations. Creatine and several metabolites, including isoleucine, trans-aconitate, and trimethylamine N-oxide (TMAO), exhibited different quantitative relationships depending on gender. Dimethylamine had a different correlation with glycine and TMAO, based on gender. The correlation of TMAO with amino acids was considerably lower in obese, compared to normal, subjects. We expect that the results will shed light on the metabolic pathways of healthy humans and will assist in the accurate diagnosis of human disease.

• The Bulletin of The Korean Astronomical Society
• /
• v.41 no.1
• /
• pp.79.3-80
• /
• 2016

We have investigated the correlation analysis between global temperature anomaly and two main factors: geomagnetic activity (aa index) of Earth external factor and CO2 of Earth internal factor. For this, we used NOAA Global Surface Temperature anomaly (Ta) data from 1868 to 2015. The aa index indicates the geomagnetic activity measured at two anti-podal subauroral stations (Canberra Australia and Hartland England) and the CO2 data come from historical ice core records and NOAA/ESRL data. From the comparison between (Ta) and aa index, we found several interesting things, First, the linear correlation coefficient between two parameters increases until 1985 and then decreases rapidly. Second, the scattered plot between two parameters shows a boundary of the correlation tendency (positive and negative correlation) near 1985. A partial correlation of (Ta) and two main factors (aa index, CO2) also shows that the geomagnetic effect (aa index) is dominant until about 1985 and the CO2 effect becomes much more important after then. These results indicate that the CO2 effect become very an important factor since at least 1985. For a further analysis, we simply assume that Ta = Ta(aa)+Ta(CO2) and made a linear regression between (Ta) and aa index from 1868 to 2015. A linear model is then made from the linear regression between energy consumption (a proxy of CO2 effect) and Ta-Ta(aa) since 1985. Our results will be discussed in view of the prediction of global warming.

• Archives of Plastic Surgery
• /
• v.47 no.6
• /
• pp.590-596
• /
• 2020

Background The introduction of the partial second toe pulp free flap has enabled superior aesthetic and functional results for fingertip reconstruction in adults. Children undergoing fingertip amputation for various reasons have limited options for reconstruction. Conventional treatment could shorten the finger, leading to poor cosmesis and function. We report 18 years of our experiences with fingertip reconstruction using partial second toe pulp free flaps in patients in early childhood. Methods Medical charts of children who had undergone fingertip reconstruction using partial second toe pulp free flaps from 2001 to 2018 were retrospectively reviewed. The surgical procedures were identical to those for adults, except for the usage of 11-0 nylon sutures. Patients' demographic data, vessel size, flap dimensions, length of the distal phalanx, and functional outcomes over the course of long-term follow-up were documented. The statistical analysis was performed with the Student t-test, the Mann-Whitney U test, and Pearson correlation analysis. Results Eighteen toe pulp flaps in 17 patients (mean age, 3.0 years) were identified. All the flaps survived without any major complications. In long-term follow-up, the flap-covered distal phalanges showed growth in line with regular development. There was no donor-site morbidity, and all children adapted to daily life without any problems. In two-point discrimination tests, the fingertip sensation recovered to almost the same level as that in the contralateral finger. Conclusions Partial second toe pulp free flaps are an excellent option for fingertip reconstruction in young children, as well as in adults.

• International Journal of Concrete Structures and Materials
• /
• v.11 no.1
• /
• pp.135-149
• /
• 2017

The prediction of the actual ultimate capacity of confined concrete columns requires partial confinement utilization under eccentric loading. This is attributed to the reduction in compression zone compared to columns under pure axial compression. Modern codes and standards are introducing the need to perform extreme event analysis under static loads. There has been a number of studies that focused on the analysis and testing of concentric columns. On the other hand, the augmentation of compressive strength due to partial confinement has not been treated before. The higher eccentricity causes smaller confined concrete region in compression yielding smaller increase in strength of concrete. Accordingly, the ultimate eccentric confined strength is gradually reduced from the fully confined value $f_{cc}$ (at zero eccentricity) to the unconfined value $f^{\prime}_c$ (at infinite eccentricity) as a function of the ratio of compression area to total area of each eccentricity. This approach is used to implement an adaptive Mander model for analyzing eccentrically loaded columns. Generalization of the 3D moment of area approach is implemented based on proportional loading, fiber model and the secant stiffness approach, in an incremental-iterative numerical procedure to achieve the equilibrium path of $P-{\varepsilon}$ and $M-{\varphi}$ response up to failure. This numerical analysis is adapted to assess the confining effect in rectangular columns confined with conventional lateral steel. This analysis is validated against experimental data found in the literature showing good correlation to the partial confinement model while rendering the full confinement treatment unsafe.

• Journal of the Korean Society for Library and Information Science
• /
• v.42 no.1
• /
• pp.273-294
• /
• 2008

In this study, it was investigated if there were some differences on the preference of researchers to grey literature among seven different subjects in the field of science and technology using citation analysis. The result shows that there were some differences among researchers, depending on the subject area. It also appears that the preference of grey literature of researchers is dissimilar in journals in English and journals in Korean, regardless of the subject area. Finally, partial correlation coefficient among nine different types of material was counted with the control of languages used and subject areas included. Among nine types of cited documents, the value of partial correlation coefficient between proceedings and miscellaneous is larger than that of any other coupled comparison This means that researchers who cite articles from proceedings tend to include information from miscellaneous at the same time.

• Journal of the Korean Society of School Health
• /
• v.29 no.1
• /
• pp.1-10
• /
• 2016

Purpose: The purpose of this study was to identify the mediating effect of stress coping type and self-esteem between life stress and suicidal ideation in nursing college students. The research design was descriptive study. Methods: A set of self-reported questionnaires was completed by 197 nursing college students, including demographic characteristics, life stress, stress coping type, self-esteem, and suicidal ideation. Data was analyzed using t-test, ANOVA, $Scheff{\acute{e}}^{\prime}s$ test, correlation analysis, and regression analysis for mediating effect by SPSS ver. 22. Results: The mean age was 20.9 years. The mean scores were 2.4, 3.6, and 1.7 out of 5 Likert scales for items of life stress, self-esteem, and suicidal ideation, respectively. The mean score for stress coping type was 2.36 out of 4 Likert scales. There was a positive correlation between suicidal ideation and life stress related to tasks, life stress related to interpersonal relationship, and emotion-focused coping of stress coping type (r=.537, p<.01); while a negative correlation between self-esteem and suicidal ideation. emotional-focused coping of stress coping type had a partial mediating effect between life stress related to tasks and suicidal ideation. Also, self-esteem had a partial mediating effect between life stress related to tasks and suicidal ideation as well as between life stress related to interpersonal relationship and suicidal ideation. Conclusion: Based on the finding of this study, it is necessary to apply various program to stress coping skill and self-esteem in order to reduce suicidal ideation in nursing college students.

• Journal of Chest Surgery
• /
• v.28 no.7
• /
• pp.649-657
• /
• 1995

From December 1993 to April 1994, to investigate complement activation and pulmonary leukostasis, thirty adult patients were studied during cardiopulmonary bypass[CPB for cardiac surgery in Department of Cardiovascular & Thoracic Surgery, Pusan Paik Hospital, Inje University. Total patients were divided into group I and II according to the purpose of study ; Group I was 15 patients undergoing CPB with bubble oxygenator, Group II was 15 patients undergoing CPB with membrane oxygenator. The results of study were summarized as follows.1. The decrease of C3 and C4 levels were observed within few minutes of beginning of CPB in all patients[P<0.05 , and this decrease was proved to be due to complement activation, not by the influence of hemodilution.2. In the correlation between the change of C3 and C4, group I showed linear correlation each other suggesting complement activation occurred through the classical pathway, group II showed a correlation at only partial sampling times suggesting complement activation via both classical and alternative pathway, however there was no significant statistical difference at the change of C3 and C4 concentrations in two groups[P>0.05 .3. After switching to partial CPB, a few difference between right atrial and left atrial WBC count was observed, but statistically not significant and median cell count difference between group I and II was not significant, too [P>0.05 . With the above result, we concluded that CPB itself contributes to the activation of complement system, but bubble oxygenator does not activate always complement system more than membrane oxygenator.

• Journal of dental hygiene science
• /
• v.21 no.2
• /
• pp.127-132
• /
• 2021

Background: Obesity and dental caries have common risk factors such as food intake, eating habits, and lifestyle. Nevertheless, there has been no consensus on the significant association between obesity and dental caries, and additional studies are needed. We investigated the relationship between obesity and dental caries in some college students in this pilot study. Methods: Forty-two obese college students (body mass index [BMI]≥25) registered at a University Obesity Clinic and 19 normal students (18.5≤BMI<25) were recruited. Oral examinations were conducted, and anthropometric data and blood samples were collected. The blood concentrations of low-density lipoprotein (LDL), high-density lipoprotein, and triglyceride were also measured. After controlling for dental plaque index, a univariate analysis of dental caries indicators related to obesity was performed; partial correlation analysis was also conducted. A nonparametric test was used for the analysis of gender-related trends due to the limited number of participants. Results: The obese group had significantly fewer missing teeth (p=0.014), missing surfaces (p=0.035), filled surfaces (p=0.038), and decayed-missing-filled surfaces (p=0.020) than the normal group. There was no difference between the males in the normal and obese groups. The females in the obese group had significantly fewer missing teeth (p=0.003), missing surfaces (p=0.003), and decayed-missing-filled surfaces (p=0.046). Partial correlation analysis showed a weak negative correlation (r=-0.256) between the blood LDL concentration and decayed-missing-filled teeth. The other obesity and dental caries indicators were not correlated. Conclusion:The blood cholesterol concentration had a negative relationship with dental caries, and there were fewer cases of dental caries in the obese group in this study. However, it is important to clarify the relationship between obesity and dental caries through a dietary survey or additional investigations considering other confounding factors.

• Journal of the Korean Data and Information Science Society
• /
• v.25 no.4
• /
• pp.807-817
• /
• 2014

This paper considers multivariate time series modelling of PM10 data in Korea collected from 2008 to 2011. We consider both temporal and spatial dependencies of PM10 by applying the sparse vector autoregressive (sVAR) modelling proposed by Davis et al. (2013). It utilizes the partial spectral coherence to measure cross correlation between different regions, in turn provides the sparsity in the model while balancing the parsimony of model and the goodness of fit. It is also shown that sVAR performs better than usual vector autoregressive model (VAR) in forecasting.

• Journal of the Computational Structural Engineering Institute of Korea
• /
• v.13 no.4
• /
• pp.461-473
• /
• 2000

This paper deals with a numerical model for the time-dependent analysis of steel and concrete composite beams with partial shear connection. A linear partial interaction theory is adopted in formulation of structural slip behavior, and the effect of concrete creep and shrinkage are considered. The proposed model is effective in simulating the slip behavior, combined with concrete creep and shrinkage, of multi-span continuous composite beams. Finally, correlation studies and several parameter studies are conducted with the objective to establish the validity of the proposed model.