• Title/Summary/Keyword: Parkinson's patients

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A Comparison of the Voice Differences of Patients with Idiopathic Parkinson's Disease and a Normal-Aging Group (파킨슨병 환자와 정상 노인의 음성비교)

  • Kang, Young-Ae;Kim, Yong-Duk;Ban, Jae-Chun;Seong, Cheol-Jae
    • Phonetics and Speech Sciences
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    • v.1 no.1
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    • pp.99-107
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    • 2009
  • In view of the hypothesis that the effects of Parkinson disease on voice production can be detected before pharmacological intervention, the voice differences of patients with Idiopathic Parkinson's disease and a healthy aging group were diagnostically analyzed with the long term object of establishing, for clinical purposes, early disease-progression biomarkers. Fifteen patients with Idopathic Parkinson's disease (prior to pharmacological intervention) and a healthy control group of 15 were selected and every voice was recorded three times using praat (ver. 5022) with a headset mic. Relevant parameters - acoustic measure of /a/ phonation, F0 related parameters, MPT related parameters, articulatory ratio, VOT - were then analyzed by MANOVA. Significant differences were found in the F0 related (low F0, high F0, F0 range) and MPT related parameters. There were also significant differences in acoustic measurements (intensity, shimmer, HNR, jitter), AMR (/$t{\Lambda}$/,/$k{\Lambda}$/) and VOT (/ta/), The findings indicated that the voice production of patients with Idiopathic Parkinson's disease have normal pitch but bad quality. In particular, with slow articulatory ratios and VOT values, the tongue tip functioning of patients was lower than for the healthy group.

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Development of Wearable Devices Equipped with Multi Sensor that can Analyze and Manage Symptoms of Parkinson's Patients as data (파킨슨 환자의 증상들을 데이터화하여 분석하고 관리할 수 있는 다양한 센서가 탑재된 웨어러블 디바이스 개발)

  • Kim, SangHyeok;Jeon, YeongJun;Kang, SoonJu
    • IEMEK Journal of Embedded Systems and Applications
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    • v.17 no.1
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    • pp.19-24
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    • 2022
  • Through the development and dissemination of embedded devices, studies that may help patients are rapidly emerging. Recently, as wearable devices have become one of the ways to diagnose diseases in daily life, they are being studied as a way to assist severely ill patients to lead their daily lives. Among them, a method of detecting and giving signals to detect and solve symptoms using acceleration sensors to diagnose Parkinson's disease is being studied, and there is no study to measure and analyze various factors that can affect Parkinson's disease. To solve them, we designed and developed a wearable device, P-Band, with various sensors capable of diagnosing related symptoms, including acceleration sensors capable of diagnosing Parkinson's disease. In this paper, the overall structure of the P-Band and the description and operation method of the measurable sensors are presented. In addition, it was confirmed that the symptoms of Parkinson's patients could be determined complexly through the results measured in actual patients.

Validating the Berg Balance Test for Patients with Parkinson's Disease (파킨슨병 환자에서 낙상군과 비낙상군에 대한 버그균형검사의 타당도)

  • Cho, Gyu-Hang;Woo, Young-Keun;Hwang, Su-Jin
    • PNF and Movement
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    • v.9 no.3
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    • pp.31-39
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    • 2011
  • Purpose : The purpose of this study was to evaluate the criterion-related validity of the Berg balance test between fallers and non-fallers in individuals with Parkinson's disease. Methods : Thirty-one patients were recruited for this study. Their initial diagnosis had been made on average $30.1{\pm}10.1$ years earlier. Score of Berg balance test showed significant correlations with indicators of motor functioning and daily living capacity. Berg balance test score was inversely associated with the unified Parkinson's disease rating scale-motor score, and Schwab and England activities of daily living rating scale. Results : In all 3 correlations, lower scores on the Berg balance test correlated with higher unified Parkinson's disease rating scale-motor scores. Results support the criterion-related validity of the Berg balance test. Conclusion : Our research results agree with other published research in suggesting that the Berg balance test may be used as a screening tool and ongoing assessment tool for patients with Parkinson's disease.

Effects of Aerobic Exercise on Disease Severity and Walking Ability in Patients with Parkinson's Disease

  • Bang, Dae-Hyouk;Noh, Hyeon-Jeong
    • The Journal of Korean Physical Therapy
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    • v.28 no.4
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    • pp.227-231
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    • 2016
  • Purpose: This study was conducted to explore the effects of aerobic exercise on the severity of disease and walking ability in patients with Parkinson's disease. Methods: Twelve patients with Parkinson's disease participated in the study. Participants were randomly assigned to either an aerobic exercise group (n=6) or a self-exercise group (n=6). All participants underwent treadmill training for 30 minutes. In addition, the experimental group (aerobic exercise group) and control group (self-exercise group) participated in a 30 minutes exercise program. In both groups, exercise was performed five times a week for four weeks. Outcome including disease severity (Unified Parkinson's Disease Rating Scale) and walking ability (10 m walking speed test, 6 minutes walking test, timed up-and-go test) were measured at baseline and after 4-weeks. Results: Significant differences in disease severity and walking ability were observed between the pre- and post-exercise groups (p<0.05). The improvement of disease severity and walking endurance was significantly higher in the experimental group than in the control group (p<0.05). Conclusion: These findings demonstrate that aerobic exercise is effective at improving disease severity and walking endurance in patients with Parkinson's disease.

Association Analysis of Parkinson's Disease using Apriori Algorithm

  • Jung, Yong-Gyu;Kim, Oh-Jin;Won, Jae-Kang
    • International journal of advanced smart convergence
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    • v.1 no.1
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    • pp.43-47
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    • 2012
  • Parkinson's disease is representative degenerative diseases of the nervous system, which is from deficiency of dopamine neurons to pass in which the gradual degeneration of the body. In this paper, open UCI repository data of Parkinson's patients is used for experiments. The classification based on correlation analysis is examined. In addition, the relationship between groups is differentiated by cluster analysis based on patients with Parkinson's disease by apriori algorithm and correlation analysis. It is used to find the properties that distinguish cluster analysis. Though the disease is the same in the basic structure, each group is compared as each gender group with the most distinctive part of the characteristics.

The Clinical Study of Parkinson‘s disease And Parkinson’s syndrome improved with Chuna-Treatment (파킨슨병, 파킨슨 의증 환자 2례에서 추나치료에 대한 증례보고)

  • Kim, Chang-Yeon;Min, Ji-Yeon;Choi, Young-Gui;Koh, Young-Tak;Jung, Young-Hoon;Cho, In-Hee;Kim, Tae-Soo
    • The Journal of Korea CHUNA Manual Medicine
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    • v.6 no.1
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    • pp.127-135
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    • 2005
  • Object : To discuss the Use of Chuna treatment in managing two patients with Parkinson's disease and/or Parkinson' syndrome Methods : This clinical study was carried out of 2 cases with confirmed by certified neurologist Parkinson's disease and/or Parkinson' syndrome. One case had been admitted from 2004.09.16 to 2004.09.24 and treated from 2004.09.26 to 2004.10.15 and the other case had been admitted from 2004.10.21 to 2004.11.06 and treated from 2004.11.08 to 2004.11.15 in the department of acupuncture and moxibustion of Ha-na oriental medical center. Results : There was significant improvement in condition of the two patients treated by Chuna treatment(upper cervical to promote CSF circulation) on Parkinson's disease or Parkinson' syndrome. Conclusion: In the case, we treated two patients of Parkinson's disease and/or Parkinson' syndrome. Chuna treatment efficiently relieved the symptoms including tremor and bradykinesia.

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Long-term Clinical Efficacy on Three Soyang Patients with Parkinson's Disease Improved by Combined Treatment of Korean-Western Medicine (소양인 파킨슨병 환자의 한양방 병행치료 장기 경과관찰 보고 3례)

  • Park, Yu-Gyeong;Lee, Mi-Suk;Kim, So-Hyoung;Bae, Na-Young
    • Journal of Sasang Constitutional Medicine
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    • v.28 no.4
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    • pp.361-371
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    • 2016
  • Objective This case study was about a long-term clinical effects after using Korean medicine treatment and western treatment in three Soyangin patients with Parkinson's disease. In this study, we reported significant improvement of non-motor and motor symptoms of these patients after Sasang constitutional medicine treatments for more than a year. Method The patients were identified as Soyangin and treated with Yangguksanhwa-tang, Hyeongbangdojeok-san and acupuncture. The Hoehn & Yahr scale, Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (UPDRS) were used to assess the overall function of the patients. And the Global Assessment Scale (GAS) was used to assess the change of chief complaints after the treatments. Result and Conclusion The non-motor and motor symptoms of Parkinson's disease improved after Sasang constitutional medicine and western medicine treatments for more than a year. Furthermore these patients' chief complaints improved without increasing of amount of western medicine (levodopa). In conclusion, this study showed that Sasang constitutional medicine with western medicine can be effective treatment for long-term clinical care of Parkinson's disease.

The Study on the Effect of Acupuncture on UPDRS and Heart Rate Variability in the Patients with Idiopathic Parkinson's Disease (태충(太衝) 양릉천(陽陵泉)의 침(針)자극이 특발성 파킨슨 환자의 UPDRS 및 HRV Parameter에 미치는 영향)

  • Jung, Ji-Chul;Kim, Kun-Hyung;Park, Yeon-Chul;Kim, Haeng-Bum;Lee, Sang-Hoon;Chang, Dae-Il;Lee, Yun-Ho
    • Journal of Acupuncture Research
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    • v.23 no.3
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    • pp.143-153
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    • 2006
  • Introduction : This study was designed to evaluate the effect of acupuncture on Unified Parkinson's Disease Rating Scale (UPDRS) and Heart Rate Variability (HRV) of patients with Parkinson's disease Methods: Subjects were voluntarily recruited through newspaper and internet advertisement. All the subjects were confirmed as idiopathic parkinson's disease by a neurologist. Acupuncture was applied 2 times a week for four weeks by oriental medical doctor at Kyung-hee University hospital. Acupuncture points used were GB34 and LR3. The patient's symptoms were assessed before and after 4 weeks of treatment by UPDRS and HRV. HRV was measured for 5 minutes before and after 4 weeks of treatment. Results : The results were as follows; 1. In both groups, UPDRS scores were significantly improved after 4 weeks compared to the pre-treatment 2. After 4 weeks of treatment UPDRS score differences between the two groups were insignificant 3. After 4 weeks of treatment HRV parameter scores showed statistically insignificant differences between the two groups. SDNN parameters of the Experimental group were significantly increased. Conclusion : This study suggests that acupuncture treatments can be applicable to improve symptoms in the patients with idiopathic Parkinson's disease. Further study on the acupuncture and HRV in the patients with Parkinson's disease is recommended.

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The Study on the Characteristics of Yangdorak in the Patients with Idiopathic Parkinson's Disease (특발성 파킨슨병 환자의 양도락 특성에 관한 연구)

  • Bang, Jun-Kyu;Park, Yeon-Cheol;Lee, Sang-Hoon;Chang, Dae-Il;Lee, Yun-Ho
    • Journal of Acupuncture Research
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    • v.23 no.6
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    • pp.153-164
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    • 2006
  • Introduction : The Aim of the Study Is to Investigate the Characteristics of Yangdorak m the Patients with Idiopathic Parkinson's Disease. Methods : Subjects Were Voluntarily Recruited by Newspapers And Internet. All the Subjects Were Confirmed as Idiopathic Parkinson's Disease by a Neurologist. The Patient's Symptoms Were Assessed by Unified Parkinson's Disease Rating Scale (UPDRS), Hoehn-Yahr (H-Y) Stage, Schwab & England Activity of Daily Living And Freezing of Gait Questionnaire(FOGQ). Sasang Constitution Was Differentiated by QSCCII. Yangdorak Was Measured after 15 minutes' Bed Rest Results : The Results Were as Follows; 1. The Average Value of Yangdorak m 50 Patients with Parkinson's Disease Was $39.01{\pm}17.97$. 2. The Mean Values of Fl, F2, F3, F4, F5 and F6 were under 40. 3. The Number of Pyesaek Was Significantly Increased According to H-Y Stage. 4. The Yangdorak Value Had No Significant Correlation between UPDRS, H-Y Stage and Duration. 5. There Was No Significant Difference in the Value of Yangdorak among Sasang Constitutions. Conclusion : This Study Suggests that Yangdorak Can Be Used as a Assistant Tool to Investigate the Patients of Parkinson's Disease. Further Study on the Yangdorak And Parkinson's Disease Is Recommended.

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The Study on the Distribution of Sasang Constitution and UPDRS(Unified Parkinson's Disease Rating Scale) among Parkinson's Disease Patients (파킨슨 환자의 사상채질 및 UPDRS 분포 연구)

  • Jung, Ji-Chul;Kim, Kun-Hyung;Park, Sang-Min;Lee, Sang-Hoon;Chang, Dae-Il;Lee, Yun-Ho
    • Journal of Acupuncture Research
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    • v.22 no.4
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    • pp.47-54
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    • 2005
  • Objectives : In order to find Sasang constitutional therapies on Parkinson's disease and to make a fundamental basis for clinical application, this study was performed. Methods : We recruit thirty five person as the disease group and we test them by QSCCII. also, We estimate them by UPDRS scale. Results : In the distribution of sasang constitution among parkinson's disease patients and controls, we can know that in the distribution of sasang constitution among parkinson's disease patients, Taeumin has a large division. but we don't find out significantly difference statistically. In the distribution of UPDRS Std. score of sasang constitution, we find out significantly difference statistically. Conclusion : Unfortunately, we fail to lead significantly difference statistically in the sasang constitution among parkinson's disease patients and controls. But, in the distribution of UPDRS Std. score of sasang constitution, we fine out significantly difference statistically. Consequencely, it is necessary that further study on the theme in the more sample.

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