• Clinical and Experimental Pediatrics
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• v.48 no.5
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• pp.545-550
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• 2005

Purpose : Newborn brain tissue has to be dissociated into a single cell suspension for flow cytometric analysis of cell death during hypoxia-ischemia. Thus the development of a method to dissociate cells from the brain tissue with least damage and maintenance of membrane and antigen integrity remains the challenge for the in vivo application of this technique. We evaluated the efficacy of mechanical or enzymatic (collagenase or tryspin) methods of brain tissue disaggregation. Methods : The extent of the damage to the plasma membrane and loss of the characteristics of the membrane induced with each dissociation method was determined by comparing the flow cytometric results labeled with both fluorescent annexin V and propidium iodide of the newborn rat pup brain tissue in the control group (n=10) and in the 48-hour after hypoxia-ischemia group (n=10). Results : In the control group, the cell percentage of damaged, apoptotic and necrotic cells of both hemispheres with the mechanical dissociation method was significantly increased compared to the trypsin or collagenase method. In the 48-hour after hypoxia-ischemia group, the cell percentage of apoptotic and necrotic cells of the right hemisphere with the collagenase method significantly increased, and live cells significantly decreased compared to the left hemisphere, control group. Although the same trend was observed, the extent of alterations made with the trypsin method was significantly less compared to the collagenase method. Conclusion : The dissociation of neonatal brain tissue for flow cytometric analysis with collagenase was most efficacious with the least cell damage and preservation of the plasma membrane characteristics.

• Journal of Korean Ophthalmic Optics Society
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• v.20 no.2
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• pp.93-104
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• 2015

Purpose: This study aimed to analyze the research trends of Ophthalmic Optic by targeting the papers published in the Journal of Korean Ophthalmic Optics Society and serve it as a basis for future researches. Methods: This study was conducted through a statistical analysis of the general characteristics, researcher characteristics, research characteristics and the research trends from total 990 papers, from the first issue to the last issue in 2014, published in the Journal of Korean Ophthalmic Optics Society. Results: Most common number of the authors of the published papers were two or three, respectively 26.8%. Most of the lead authors belong to the schools in Jeolla-do province (31.3%). Most of the educational system of which lead authors belong to is four-year-course system (43.0%). Most common research methods were optometric tests (40.9%). The most common subjects of researches are about the field of optometry (29.8%). The study shows that there were significant differences in the research methods depending on the school systems of the universities to which the lead authors belong (p=0.000). There also were significant differences in the school systems of the universities to which the lead authors belong, and research methods depending on the research subjects (p=0.000). There were meaningful differences according to the period divisions (1996 to 2004 and 2005 to 2014), i.e. the number of authors has been growing, and it is the same case for the number of the authors who belong to four-year-course universities (p=0.000). The number of papers on optometry and contact lenses have increase. The benefits of the research funds have also increased (p<0.005). In addition, the number of the lead authors in the Seoul and Chungcheong province have increased (p=0.000). Conclusions: For the development of the Ophthalmic Optics, it is necessary to broaden the stratum of researchers and deal with various research topics, And joint efforts between eyewear industry and academia and international cooperations are needed.

• Tuberculosis and Respiratory Diseases
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• v.48 no.6
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• pp.837-852
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• 2000

Backgrounds : Today, tuberculosis cannot only be cured medically, but also controlled by public health. Despite the overall worldwide decline in tuberculosis, the disease continues to be a significant problem among developing countries and in the slums of large cities in some industrialized countries. Particularly, this communicable disease has come into the public health spotlight because of its resurgence in the 1990's. our country has been operating the Korean National Tuberculosis Control Program since 1962, focusing around public health centers. Therefore, this study aims to compare the effectiveness of tuberculosis control activities, one of the major public health activities in Korea, by producing indexes, such as the yearly registration rate per 100,000 population and treatment compliance of tuberculosis on in small areas (communities). Methods : This work was accomplished by constructing a time-series analytic model using data from "1980~2000: the Yearly Statistical Report" with patient registry data of 234 City. County. District public health centers and by identifying the factors influencing the tuberculosis indexes. Results : The trends of pulmonary tuberculosis positive point prevalence and pulmonary tuberculosis negative point prevalence on X-ray screening have declined steadily, beginning in 1981 and continuing to 1998 by region (city, county, district). Although the tuberculosis mortality rate steadily shows a declining trend by year and region, but Korea still ranks first among 29 OECD countries in 1998, with a tuberculosis mortality rate of 7.1 per 100,000 persons, according to the time-series analysis for fatal diseases. Conclusion : The results of the study will form the fundamental basis of future regional health care planning and the Korean Tuberculosis Surveillance System on 2000. Since the implementation of local autonomy through the Local Health Act of 1995, it has now become vita1 for each city, county, district public health centers to determine its own priorities for relevant health care management, including budget allocation and program goals.

• Journal of the Korean Institute of Landscape Architecture
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• v.20 no.3
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• pp.64-78
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• 1992

In this study, elementary school students of both urban and rural areas as its subjects were asked to draw 'A beautiful landscape' by employing the perspective representation technique, i. e., the Perception Map, and to write down the elements comprising 'A beautiful landscape' in the questionnaire sheets. By doing so, an attempt was made 1) to analyze whether there are differences in perceiving 'A beautiful landscape' according to the differences of the environment in which they were brought up ; and, if there are differences. 2) to identify them ; and based on that , 3) to present basic data for evaluation on landscape, on its preference analysis and for Park Planning. The summary of this study is as follows ; 1) The main elements, elementary school students think, comprising 'A beautiful landscape' are 25 ones such as Sky(7), Sea(2), Water(2), Topography(5), Plants(5), Animals(3), School(1), Rural village(1). The natural elements showing a difference are ; Water fall in urban areas and School landscape in rural areas ; the artificial elements are ; City groups(Structures, Facilities, Necessities, Transportation means and Space) in urban areas and School groups in rural areas. Especially, in case of rural area children, they regard 'Trees' as an essential element to be 'A beautiful landscape' comparing to those in urban areas. 2) According to the analysis result on the correlation between the elements comprising a beautiful rural landscape and a beautiful ruban landscape, the correlation between boys and girls is high, showing the same trend with any difference. In comparison of urban areas with rural areas, there is no difference between natural elements, but in artificial elements(7 groups without family) the correlation is quite low, showing that all comprising elements are not the same between rural schools and cities, between schools within the same areas, and between schools of different areas. 3) In identifying the names of elements comprising 'A beautiful landscape', Back-Du Mountain and Sorak Mountain are shown the highest frequency in the category of mountains. In the names of trees and flowers, the elementary school children are thought to consider the kinds of trees and flowers they can see always at hand, i. e., those in their school ground where they spend most of their day time. 4) In the analysis of the numbers of comprising elements according to the responses in the questionnaire sheets and in the Perception Map, 'less than 10' is the most frequently counted number of comprising elements by individual students regardless of rural and urban differences. When the total frequency is divided by the number of students, the mean score is 6-7 without any differences between rural and urban areas, implying that there are no differences in the expression ability between urban and rural schools. 5) According to the result of classyfying and analysizing the landscape appeared on the Perception Map by similar elements and by similar scenes, 'A beautiful landscape' thought by elementary school children is defined not as a standardized form but as 11 types such as the landscape of fields, the landscape of a sea, the landscape of a rural village, a type where elements are assembled, the landscape of cities, the landscape of a school, the landscape coming out of a imagination, and other landscape. Both rural and urban children all consider the landscape of mountains and field and the landscape where several elements are assembled as a commonly beautiful one. Among the landscapes showing rural and urban differences, it can be analyzed that urban children regard the landscapes of cities, imagination, and waterfalls as something characteristic, while rural children regard the landscape of schools and rural villages as something characteristic.

• Journal of the Korean Society of Marine Environment & Safety
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• v.17 no.3
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• pp.203-218
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• 2011

Long-term trends and distribution patterns of water quality were investigated in the Yeoja Bay of South Sea, Korea from 1976 to 2010. Water samples were collected at 3 stations and physicochemical parameters were analyzed including water temperature, salinity, hydrogen ion concentration (pH), dissolved oxygen (DO), chemical oxygen demand (COD), suspended solids (SS) and nutrients. Spatial distribution patterns of temperature, pH and DO were not clear among stations but the seasonal variations were distinct except ammonium. The trend analysis by principal component analysis (PCA) during 31 years revealed the significant variations in water quality in the study area. Spatial water qualities were discriminated into 2 clusters by PCA; station cluster 1 and 2~3. Annual water qualities were clearly discriminated into 4 clusters by PCA. By this multi-variate analysis, the annual trends were summarized as the followings; water temperature, COD and SS tended to increase from late 1970's, decreased salinity, and increased phosphate from 1991 to 2001 and increased dissolved inorganic nitrogen. Water quality was showed by the input of fresh water same as those of Kyoungin coastal area, Asan coastal area, Choensoo bay, Gunsan coastal and Mokpo coastal area in the Yeoja Bay.

• Journal of Korea Port Economic Association
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• v.32 no.1
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• pp.29-58
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• 2016

The purpose of this paper is to show the clustering trend and the comparison of empirical results and is to choose the clustering ports for 3 Korean ports(Busan, Incheon and Gwangyang Ports) by using the bootstrapped DEA(Data Envelopment Analysis) and game Cross-efficiency models for 38 Asian ports during the period 2003-2013 with 4 input variables(birth length, depth, total area, and number of cranes) and 1 output variable(container TEU). The main empirical results of this paper are as follows. First, bootstrapped DEA efficiency of SW and LT is 0.7660, 0.7341 respectively. Clustering results of the bootstrapped DEA analysis show that 3 Korean ports [ Busan (6.46%), Incheon (3.92%), and Gwangyang (2.78%)] can increase the efficiency in the SW model, but the LT model shows clustering values of -1.86%, -0.124%, and 2.11% for Busan, Gwangyang, and Incheon respectively. Second, the game cross-efficiency model suggests that Korean ports should be clustered with Hong Kong, Shanghi, Guangzhou, Ningbo, Port Klang, Singapore, Kaosiung, Keelong, and Bangkok ports. This clustering enhances the efficiency of Gwangyang by 0.131%, and decreases that of Busan by-1.08%, and that of Incheon by -0.009%. Third, the efficiency ranking comparison between the two models using the Wilcoxon Signed-rank Test was matched with the average level of SW (72.83 %) and LT (68.91%). The policy implication of this paper is that Korean port policy planners should introduce the bootstrapped DEA, and game cross-efficiency models when clustering is needed among Asian ports for enhancing the efficiency of inputs and outputs. Also, the results of SWOT(Strength, Weakness, Opportunity, and Threat) analysis among the clustering ports should be considered.

• Korea Science and Art Forum
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• v.21
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• pp.31-43
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• 2015

Information and Communications Technology (ICT) is one of the technologies which represent the core value of the creative economy. It has served as a vehicle connecting the existing industry and corporate infrastructure, developing existing products and services and creating new products and services. In addition to the ICT, new devices including big data, mobile gadgets and wearable products are gaining a great attention sending an expectation for a new market-pioneering. Further, Internet of Things (IoT) is helping solidify the ICT-based social development connecting human-to-human, human-to-things and things-to-things. This means that the manufacturing-based hardware development needs to be achieved simultaneously with software development through convergence. The essential element the convergence between hardware and software is OS, for which world's leading companies such as Google and Apple have launched an intense development recognizing the importance of software. Against this backdrop, the status-quo of the software market has been examined for the study of the present report (Korea Evaluation Institute of Industrial Technology: Professional Design Technology Development Project). As a result, the software platform-based Google's android and Apple's iOS are dominant in the global market and late comers are trying to enter the market through various pathways by releasing web-based OS and similar OS to provide a new paradigm to the market. The present study is aimed at finding the way to utilize a smart content by which anyone can be a developer based on OS responding to such as social change, newly defining a smart content to be universally utilized and analyzing the market to deal with a rapid market change. The study method, scope and details are as follows: Literature investigation, Analysis on the app market according to a smart classification system, Trend analysis on the current content market, Identification of five common trends through comparison among the universal definition of smart content, the status-quo of application represented in the app market and content market situation. In conclusion, the smart content market is independent but is expected to develop in the form of a single organic body being connected each other. Therefore, the further classification system and development focus should be made in a way to see the area from multiple perspectives including a social point of view in terms of the existing technology, culture, business and consumers.

• Journal of Korean Society of Disaster and Security
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• v.17 no.1
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• pp.9-16
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• 2024

In Korea, as disasters become larger and more complex, there is a trend of shifting from a focus on response and recovery to a focus on prevention and preparedness. In order to prevent and prepare for disasters, each local government manages disaster management resources by stockpiling them. However, although disaster management resources are stored in individual warehouses, they are managed by department rather than by warehouse, resulting in insufficient management of disaster management resources due to the heavy workload of those in charge. In order to intensively manage these disaster management resources, an integrated disaster management resource management center is established and managed at the metropolitan/provincial level. In the case of Gangwon-do, the subject of this study, a warehouse is rented and operated as an integrated disaster management resource management center. When leasing an integrated management center, there is the inconvenience of having to move the location every 1 to 2 years, so it is deemed necessary to build a dedicated facility in an available site. To select a location candidate, network analysis was used to measure access to and use of facilities along interconnected routes of networks such as roads and railways. During network analysis, the Location-Allocation method, which was widely used in the past to determine the location of multiple facilities, was applied. As a result, Hoengseong-gun in Gangwon-do was identified as a suitable candidate site. In addition, if the integrated management center uses our country's logistics system to stockpile disaster management resources, local governments can mobilize disaster management resources in 3 days, and it is said that it takes 3 days to return to normal life after a disaster occurs. Each city's disaster management resource stockpile is 3 days' worth per week, and the integrated management center stores 3 times the maximum of the city's 4-day stockpile.

• Phonetics and Speech Sciences
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• v.16 no.2
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• pp.49-58
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• 2024

This study aimed to compare the acoustic measurements of speech samples recorded from individuals with normal voices using various devices: the Computerized Speech Lab (CSL), a unidirectional wired pin-microphone (WIRED) suitable for smartphones, the built-in omnidirectional microphone (SMART) of smartphones, and Bluetooth-connected wireless earphones, specifically the Galaxy Buds2 Pro (WIRELESS). This study included 40 normal adults (12 males and 28 females) who had not visited an otolaryngologist for respiratory diseases within the past three months. Participants performed sustained vowel /a/ phonation for four seconds and reading tasks with sentences ("Walk") and paragraphs ("Autumn") in a sound-treated booth. Recordings were simultaneously conducted using the four different devices and synchronized based on the CSL-recorded samples for analysis using the MDVP, ADSV, and VOXplot programs. Compared with CSL, the Cepstral Spectral Index of Dysphonia (CSID_V, CSID_S) and Acoustic Voice Quality Index (AVQI) values were lower in the WIRED and higher in the SMART. The opposite trend was observed for the L/H spectral ratios (SR_V and SR_S), and the WIRELESS demonstrated task-specific discrepancies. Furthermore, both the fundamental frequency (F0) and the cepstral peak prominence of the vowel samples (CPP_V) had intraclass correlation coefficient (ICC) values above 0.9, indicating high reliability. These variables, F0 and CPP_V were considered highly reliable for voice recordings across different microphone types. However, caution should be exercised when analyzing and interpreting variables such as the SR, CSID, and AVQI, which may be influenced by the type of microphone used.

• Journal of Korean Society of Environmental Engineers
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• v.31 no.11
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• pp.1041-1050
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• 2009

The ambient temperature and concentration of carbon dioxide in Gwangju and the reducing method of temperature, air pollutants were investigated using the atmospheric data in Gwangju. Average ambient temperature ($T_{a-ave}$ was $13.5^{\circ}C$ during 1961 to 2008. The temperature was predicted as increasing of about $2.7^{\circ}C$ in 2108 after 100 years using the trend line of regression equation. Carbon dioxide was 370.7 and 391.4 ppm at Anmyundo, in 1999 and 2008, respectively, showing proportionally increased as ambient temperature. The temperature at Gwangju, $14.2^{\circ}C$ during 1997 to 2008, was a little higher than at neighboring counties as Naju, Damyang, Hwasoon, and Jangsung. In Gwangju, Spring will start in mid-January of 2108, Summer in mid-May, Autumn in mid-October, and Winter in last-December. The average relative humidity in the air ($RH_{a-ave}$) was gradually decreased as the temperature inversely increased. The average $CO_2$ was 457 ppm, which is 65.6 ppm higher than that in Anmyundo, korean background area of $CO_2$ in 2008. Carbon dioxide showed positive correlation, both of them, with carbon monoxide (0.87) and relative humidity (0.48).