• 제목/요약/키워드: Pap1

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Journey of the Human Papillomavirus (HPV) in a Developing Country over 5 Years (2010 - 2015)

  • Danial, M;Sivasangari, S;Arulappen, AL;Ong, LM
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권3호
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    • pp.1363-1368
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    • 2016
  • Human papillomavirus (HPV) is a prevalent sexually transmitted infection with serious medical, sexual, and relationship consequences. HPV vaccine protection is available globally but unfortunately vaccine uptake is inconsistent everywhere. From this study, it was observed that the awareness of cervical cancer, HPV virus and HPV vaccination in Malaysia is high, at 83.1%, 73.9% and 73.3% of respondents, respectively. However, a considerably low percentage had undergone HPV vaccination (8.6%) compared to those who had experienced a Pap smear (32.9%). Awareness between cervical cancer and HPV virus and vaccination was low. Health care providers and the governing bodies have to play a vital role in disseminating holistic information on the vaccine and the importance of getting vaccinated to the public more vigorously in Malaysia.

Assessment of Cervical Cytological Data in Albanian Females

  • Filipi, Kozeta;Xhani, Anila
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권5호
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    • pp.2129-2132
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    • 2014
  • Background: Cervical cancer is one of the most common female malignancies with high mortality rates in developing countries. Our purpose was to determine the prevalence of cervical cytological abnormalities by cervical cytology (CC) and the analysis of risk factors in Albanian population. Materials and Methods: A total of 5,416 conventional pap smear tests collected between January 2009 and January 2012 from Tirana University Hospital Obstetrics-Gynecology "Queen Geraldine" were retrospectively analyzed. Results: A total of 258 (4.8%) cases had epithelial abnormalities. The numbers and rates were as follows: atypical squamous cell of undetermined significance (ASCUS; n=150 [2.76%]); atypical glandular cells of undetermined significance (AGUS; n=8 [0.14%]); low-grade squamous intraepithelial lesion (LSIL; n=87 [1.6%]); high- grade squamous intraepithelial lesion (HSIL; n=10 [0.18%]); and squamous cell carcinoma (SCC; n=3 [0.05%]). Conclusions: The prevalence of cervical cytological abnormality in our study was 4.8%. A larger community-based study may establish the exact prevalence of malignant and premalignant lesions, so as to plan for future screening.

Knowledge and Practices on Breast and Cervical Cancer Screening Methods among Female Health Care Workers: A Sri Lankan Experience

  • Nilaweera, Riw;Perera, S.;Paranagama, N.;Anushyanthan, As
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권4호
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    • pp.1193-1196
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    • 2012
  • Breast and cervical cancer are the most common causes of cancer mortality among women worldwide, but they are largely preventable. There are limited data on knowledge and practices on screening methods of breast and cervical cancers among female health care workers in Sri Lanka, in spite of having an organized screening programme islandwide. A cross-sectional survey was conducted among 219 female health care workers including public health midwives (68.9%) selected from 6 districts in Sri Lanka using convenient sampling methods. A self-administered questionnaire was used as a pre-test in a capacity building training programme to collect the data. The mean (SD) duration of work experience of the respondents was 12 years and 52.5% were aged over 35 years. Most (76.7%) were married, and afamily history of cancer was reported by 24.2%. Over 98% knew about self breast examination. Even though 84.1% practiced it, only 47.9% practiced it on a monthly basis. Clinical breast examination and mammography were known by 94.1% and 64.3% respectively. Only 19.2% had undergone a clinical braest examination within one year and 3.6% had ever undergone a mamography. Only 76.3% knew that a Pap smear detects precancerous stage of cervical cancer. Among 169 married workers, 73.4% had never had a Pap smear and only 17.2% had got it done within the preceding 5 years. Among the reasons for not doing a pap smear within 5 years, 47.0% belived it as not nescessary, 17.3% due to fear/dislike, 23.2% as not having symptoms, 3% had not known about it and 3% not known about availability of services. The study findings suggest that the knowledge and practices on breast and cervical cancer screening methods among female health care workers need to be improved. Considering the role that health care workers play in communicating health behaviors to the general public, strengthening health education interventions for this group of females is essential.

Acceptability of Self-Sampling HPV Testing Among Thai Women for Cervical Cancer Screening

  • Oranratanaphan, Shina;Termrungruanglert, Wichai;Khemapech, Nipon
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권17호
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    • pp.7437-7441
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    • 2014
  • Background: Acceptability of self-sampling HPV testing is confirmed worldwide. However, some cultural differences may affect this question. Therefore, this study was conducted to evaluate the acceptability of self-sampling HPV testing in Thai women. Materials and Methods: One hundred women aged 30-65 years with an intact cervix were included in this study. The participants were asked to do the Pap test by physicians and then brush type self-sampling instruments were assigned for self-collection and finally completed a questionnaire for acceptability evaluation. The questionnaire contains 2 parts. Part one covered general information of the participants and part two is the acceptability questions. Results: Mean age was 40.6 years. The incidence of high risk HPV detection in this study was 16%. The most common reason for doing Pap smear was for annual checkup. On the topic of ease of use, 85 % of the subjects agreed. Most of the participants (82%) reported that they felt less pain. However, reliability of the result was not satisfactory because 37% of the participants hesitated to rely on the results of the test. According to the price, if the price is less than 1,000 Baht (32.59 Baht = 1USD), 82% of the subjects would use it for their next screening. Conclusions: The acceptability of self-sampling device in this study is quite good but the reliability of the test was questioned by some of the participants. Moreover, the price of the test in Thailand may also influence the acceptability of the test.

Cervical Cancer Screening: Recommendations for Muslim Societies

  • Khodakarami, Nahid;Farzaneh, Farah;Yavari, Parvin;Akbari, Mohamad Esmaeil
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권1호
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    • pp.239-247
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    • 2016
  • Background: The overall cervical cancer incidence rate is low in Iran; however, because of a higher risk of death for cervical cancer, a disease that kills women in middle age, a cervical cancer control program is needed. The aim of this study was to provide consensus recommendation for cervical cancer prevention in Iran and other Muslim societies with low incidences of cervical cancer. Materials and Methods: Through a practical guideline development cycle, we developed six questions that were relevant to produce the recommendation. We reviewed 190 full text records of cervical cancer in Iran (1971 to 2013) of which 13 articles were related to the data needed to answer the recommendation questions. We also reviewed World Health Organization, IARC, GLOBOCAN report, Iran Ministry of Health cancer registry report and 8 available foreign countries guidelines. Lastly, we also evaluated the Pap smear results of 825 women who participated in the Iranian HPV survey, of whom 328 were followed-up after a 5-year interval. Results: The obtained data highlighted the burden of HPV and cervical cancer situation in Iran. Experts emphasized the necessity of a cervical cancer screening program for Iranian women, and recommended an organized screening program with a cytological evaluation (Pap smear) that would start at the age of 30 years, repeated every 5 years, and end at the age of 69 years. Meanwhile, there is no need for screening among women with a hysterectomy, and screening should be postponed to post-partum among pregnant women. Conclusions: An organized cervical cancer screening is a necessity for Iran as more than 500-900 women in middle age diagnosed with an invasive cervical cancer every year cannot be ignored. This recommendation should be taken into account by the National Health System of Iran and Muslim countries with shared culture and behavior patterns. CUBA HPV test could be consideration in countries Muslim country with appropriate budget, resources and facility.

Gravimetric Measurements and Theoretical Calculations of 4-Aminoantipyrine Derivatives as Corrosion Inhibitors for Mild Steel in Hydrochloric Acid Solution: Comparative Studies

  • Firas F. Sayyid;Ali M. Mustafa;Slafa I. Ibrahim;Mustafa K. Mohsin;Mahdi M. Hanoon;Mohammed H. H. Al-Kaabi;A. A. H. Kadhum;Wan Nor Roslam Wan Isahak;A. A. Al-Amiery
    • Corrosion Science and Technology
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    • 제22권2호
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    • pp.73-89
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    • 2023
  • Due to continuous promotion of green alternatives to toxic petrochemicals by government policies, research efforts towards the development of green corrosion inhibitors have intensified recently. The objective of the current work was to develop novel green and sustainable corrosion inhibitors derived from 4-aminoantipyrine to effectively prevent corrosion of mild steel in corrosive environments. Gravimetric methods were used to investigate corrosion inhibition of 4-((furan-2-ylmethylene)amino)antipyrine (FAP) and 4-((pyridin-2-ylmethylene)amino)antipyrine (PAP) for mild steel in 1 M HCl. FAP and PAP were subjected to quantum chemical calculations using density functional theory (DFT). DFT was used to determine the mechanism of mild steel corrosion inhibition using inhibitors tested in HCl. Results demonstrated that these tested inhibitors could effectively inhibit mild steel corrosion in 1.0 M HCl. At 0.0005 M, these inhibitors' efficiencies for FAP and PAP were 93.3% and 96.5%, respectively. The Langmuir adsorption isotherm was obeyed by these inhibitors on the mild steel surface. Values of adsorption free energies, ΔGoads, revealed that FAP followed chemical and physical adsorptions.

Influences of different light sources and light/dark cycles on anthocyanin accumulation and plant growth in Petunia

  • Ai, Trinh Ngoc;Naing, Aung Htay;Kim, Chang Kil
    • Journal of Plant Biotechnology
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    • 제43권1호
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    • pp.119-124
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    • 2016
  • Anthocyanin accumulation and plant growth were examined in petunia (NT and $T_2$ transgenic plants) by determining the effects of different sources of light and varying light/dark cycles. Red light significantly enhanced anthocyanin content of B-peru+mPAP1; however, it had a negative effect on anthocyanin production in RsMYB1 plants. In general, white light was found to be reasonable for anthocyanin accumulation in all plants. In case of light/dark cycles, application of seven days of light:14 days of dark significantly enhanced anthocyanin content. We found that anthocyanin content detected in transgenic plants expressing anthocyanin regulatory transcription factor genes (B-peru+mPAP1 or RsMYB1) was higher than that in NT plants in all treatments. Plant growth was also influenced by the different light sources and dark/light cycles. Taken together, our results suggest that light source and light/dark cycle play an important role in anthocyanin production and plant growth. The choice of the optimal conditions is also important for anthocyanin production and plant growth depending on NT or transgenic plants carrying anthocyanin regulatory transcription factors.

멸구$\cdot$매미충의 종류에 따른 살충제의 선택독성 (Selective Toxicity of Insecticides to Plant-and Leaf-hoppers)

  • 최승윤;이형래
    • 한국응용곤충학회지
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    • 제15권1호
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    • pp.1-6
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    • 1976
  • 본 시험은 애멸구, 흰등멸구, 벼멸구 및 끝동매미충을 공시하여 몇 가지 수도해충 방제용 살충제의 선택독성을 검토하기 위해 실시하였다. 유기인계 살충제로서 Diazinon $(34\%\; 유제 3\%\; 입제)$을 공시하였고 Carbamate계 살충제로서 MPMC$(Meobal 50\%\; 수화제)$, BPMC $(Bassa 50\% 유제)$, Carbofuran (Curator. $3\%$ 입제)을 공시하였다. 유제와 수화제는 유묘의 침지에 의한 접촉법으로 실시하였고 입제는 Pot를 사용하여 수면처리에 의하여 행하였다. 1. 유묘침지시험에 있어서 Diazinon MEP, PAP제는 벼멸구에 대한 살충력이 현저이 낮었고 MEP제는 끝동매미충에 대해서도 살충력이 낮었으나 MPMC제는 네 가지 공시충에 대하여 선택독성이 비교적 적었다. 끝동매미충에 대한 MEP제의 선택독성을 제외하고는 애멸구, 흰등멸주, 끝동매미충에 대한 살충력은 보다 높아 선택독성을 인정할 수 없었라. 재차 시험에 있어서도 유기인제인 Diazinon, MEP 및 PAP는 벼멸구에 대하여 살충력이 심히 낮었으나 Carbamate계인 BPMC, MPMC는 살충력이 좋았다. 2. 입제의 수면처리시험에서도 Carbamate계 살충제 Carbofuran은 애멸구, 흰등멸구, 벼멸구, 끝동매미충에 대하여 비교적 높은 살충제을 보였으나 유기인계 살충제 Diazinon은 벼멸구에 대하여 살충력이 심히 낮었다. 3. 제제의 형태에 상관없이 유기인계 살충제는 Carbamate계 살충제에 비하여 멸구$\cdot$매미충의 종에 따른 선택독성이 거의 없었다.

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과실채소중(果實菜蔬中) 유기인계(有機燐系) 농약잔류(農藥殘留)에 관(關)한 연구(硏究) (Organophosphorus Insecticide Residues in Fruits and Vegetables)

  • 서윤수;류홍일;김인기;김학엽;김성환
    • 한국환경농학회지
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    • 제3권2호
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    • pp.30-36
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    • 1984
  • 수종(數種)의 과실채소류(果實菜蔬類)에 대(對)한 유기린계(有機燐系) 살충제들의 잔유량(殘留量)을 조사(調査)한 결과(結果)는 다음과 같다. 1) 채소류(菜蔬類)(무우, 배추, 오이, 토마토)에서 diazinon의 검출률(檢出率)은 20%, 검출범위(檢出範圍)는 부검출(不檢出)${\sim}0.020ppm$ 이었으며, 검출시료(檢出試料)의 평균(平均)은 0.004ppm이었다. DEP는 검출률(檢出率)이 52.5%, 검출범위(檢出範圍)는 부검출(不檢出)${\sim}0.273ppm$이었으며, 검출시료(檢出試料)의 평균(平均)은 0.096ppm 이었다. Malathion의 검출률(檢出率)은 15%이며 검출범위(檢出範圍)는 부검출(不檢出)${\sim}0.038ppm$이고 검출시료(檢出試料)의 평균(平均)은 0.021ppm 이었다. 2) 고추에서는 EPN은 전시료(全試料)에서 부검출(不檢出) 되었으며, PAP는 1점(點)의 시료(試料)에서만 0.006ppm으로 검출(檢出)되었다. 3) 포도에서의 PAP는 검출률(檢出率)이 20%이고 검출범위(檢出範圍)는 부검출(不檢出)${\sim}0.008ppm$ 이었으며 검출시료(檢出試料)의 평균(平均)은 0.006ppm 이었다. EPN은 전시료(全試料)에서 부검출(不檢出)되었으며 MEP의 검출률(檢出率)은 20%, 검출범위(檢出範圍)는 부검출(不檢出)${\sim}0.007ppm$이며 검출시료(檢出試料)의 평균(平均)은 0.005ppm이었다. 4) 복숭아에서 EPN은 전시료(全試料)에서 부검출(不檢出)이었고, demeton-methyl은 검출률(檢出率)이 30%, 검출범위(檢出範圍)는 부검출(不檢出)${\sim}0.047ppm$이였으며, 검출시료(檢出試料)의 평균(平均)은 0.032ppm이었다. parathion은 1점(點)의 시료(試料)에서만 0.003ppm으로 검출(檢出)되었다. 5) 본(本) 조사결과(調査結果)에서 대상농작물(對象農作物)인 국내생산(國內生産) 과실채(果實菜) 소중(蔬中) 유기린계(有機燐系) 농약(農藥)의 잔유량(殘留量)은 국내외(國內外)의 잔류허용기준(殘留許容基準)에 훨씬 미달(未達)되는 수준(水準)이었으며 그 잔유량(殘留量)도 세정(洗淨)이나 조리과정(調理過程)에서 상당한 량(量)이 제거(除去)될 것으로 생각되므로 실제(實際)로 인체내(人體內)에 섭취(攝取)되는 잔유농약(殘留農藥)의 량(量)은 극소(極小)한 것으로 판단(判斷)된다.

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살충제 살포가 수도해충과 천적의 밀도에 미치는 영향[1] 벼멸구와 포식천적 황산적거미에 대한 몇가지 살충제의 선택독성에 관한 연구 (Effects of Insecticide Application on the Populations of the Paddy Rice Insect Pests and Their Natural Enemies [1] Selective Toxicity of Insecticides for Brown Planthopper, Nilaparvata lugens, and Predaceous Paddy Spider, Pirate subpiraticus)

  • 장영덕;송유한;최승윤
    • 한국응용곤충학회지
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    • 제18권4호
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    • pp.149-152
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    • 1979
  • 현재 우리나라에서 사용되고 있는 수종의 수도용 살충제들에 대하여 벼멸구와 이의 주요천적인 황산적거미에 대한 상대독성을 실내에서 미량국소 처리방법으로 반치사약량을 조사 비교한 결과 PAP(0.4), MPP (0.7), MEP(1.8), Diazinon(2.8) , Carbofuran(7.5), NAC(11.3), BPMC(17.5), Pyridaphenthion(35.9), MIPC(65.7)의 순이었으며 특히 MIPC, Pyridaphenthion은 벼멸구와 황산적거미에 대해 선택성을 나타내었다.

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