• Journal of Oriental Neuropsychiatry
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• v.29 no.4
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• pp.305-314
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• 2018

Objectives: The objective of this study was to report the clinical effectiveness of the complex Korean medicine therapy and M&L (Mindfulness & Loving presence) psychotherapy on the patient with panic disorder. Methods: The subject for this study was the patient diagnosed with panic disorder who complained about intermittent panic attack and accompanying insomnia. During the treatment period, the patient received complex Korean therapy and M&L psychotherapy. The clinical effects were evaluated through Beck Depression Inventory (BDI), Hamilton Depression Rating Scale (HDRS), State-Trait Anxiety Inventory (STAI), Panic Disorder Severity Scale (PDSS), and Pittsburgh Sleep Quality Index (PSQI). Results: After the complex Korean medicine therapy and M&L psychotherapy, the overall symptoms of depression, anxiety, panic disorder and insomnia of the patient were lessened in a relatively short period. No specificities or adverse effects were reported during the treatment period. Conclusions: This study established that the complex Korean medicine therapy and M&L psychotherapy was effective in treating patients with panic disorder.

• Journal of Korean Medical classics
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• v.36 no.2
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• pp.49-60
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• 2023

Objectives : This study aims to examine the 13 diagnostic criteria symptoms of panic disorder in Korean Medicine and to establish a literature basis for treating panic disorder in the clinical setting. Methods : Symptoms in Korean Medicine corresponding to each diagnostic criterion were comprehensively reviewed based on the Uihagimmun(醫學入門) and the Donguibogam(東醫寶鑑). Treatments were investigated as well. Results : According to Korean Medicine, panic disorder is believed to be caused by the stagnation of qi, leading to the retention of phlegm and fluids. Conclusions : Yijintang(二陳湯) can serve as a fundamental prescription for treating panic disorder, and it can be easily adapted to each patient's symptoms through modification of the ingredients.

• Anxiety and mood
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• v.10 no.2
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• pp.176-181
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• 2014

Objective : Despite high prevalence and effective treatments of panic disorder, lots of patients are not properly treated due to lack of awareness of the disorder. This study summarizes and presents the results from Public Awareness Survey of Panic Disorder during the Mental Health Exposition held in Seoul in April, 2014. Methods : A total of 401 participants who visited the booth of the Korean Academy of Anxiety Disorder agreed and completed the survey. The questionnaires comprised of three sections; first, after given a case of patient with panic disorder, participants were asked to choose a diagnosis and treatment options. Second, participants were asked to differentiate the symptoms of panic disorder from those of other mental disorders and answer where they acquired the knowledge of the disorder. Third, visual analogue scales were used to get more detailed information for several issues about panic disorder. The incidence and ratio for each question were provided and compared. Results : Among the participants, 78% reported a patient within the case need treatment, and 30% accurately recognized it was panic disorder. As for treatment needed, 40% selected psychotherapy by psychiatrists, 28% chose counseling by psychologist, 23% said that they can overcome it by self-care. Only 2% of participants selected the pharmacotherapy as treatment needed. Approximately 40% of participants have encountered information about the disorder from gossips of celebrities, 32% from mass-media, and merely 6% from medical professionals. About 80% of participants could discriminate the symptom of panic disorder from those of depression, schizophrenia, or generalized anxiety disorder. Conclusion : Our results suggest that substantial proportions of participants have the awareness of panic disorder, while as for treatment they were strongly biased against pharmacologic treatments. Most of their source of the awareness was not relied upon professional information. Efforts for giving correct information and increasing public awareness of panic disorder are needed to bridge a gap between professionals and general public.

• The Journal of the Korean life insurance medical association
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• v.29 no.1
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• pp.7-11
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• 2010

Anxiety disorders Anxiety disorders are among the most prevalent mental disorders in the general population. Anxiety disorders can be viewed as a family of related but distinct mental disorders, which include following as classified in the text revision of fourth edition of Diagnostic and Statistical Manual Disorders(DSM-IV-TR): (1) panic disorder with or without agoraphobia; (2) agoraphobia with or without panic disorder; (3) specific phobia; (4) social phobia; (5) obsessive-compulsive disorder; (6) posttraumatic stress disorder; (7) acute stress disorder; (8) generalized anxiety disorder. An acute intense attack of anxiety accompanied by feeling of impending doom is known as panic disorder. The term phobia refer to an excessive fear of a specific object, circumstance, or situation. Obsessivecompulsive disorder is represented by a diverse group of symptoms that include intrusive thoughts, rituals, preoccupations, and compulsions. Posttraumatic stress disorder is a condition marked by development of symptoms after exposure to traumatic life events. Generalized anxiety disorder is defined as excessive anxiety and worry about several events or activities for most days during at least a 6-month period.

• Korean Journal of Biological Psychiatry
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• v.14 no.1
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• pp.55-60
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• 2007

Objectives : There have been many association studies of panic disorder. However, studies about the dopaminergic function in panic disorder have been few. This study was aimed to examine the possible association of dopamine transporter gene(DAT1) polymorphism and panic disorder in Korean population. Methods : Ninety-eight patients with panic disorder(43 male(46.9%), mean age $42.13{\pm}10.88$ years) and one hundred and thirteen comparison subjects(67 male(40.7%), mean age $33.14{\pm}8.55$ years) were tested for DAT1 polymorphism. Genotypes of DAT1 with variable number of tandem repeats(VNTR) were determined using polymerase chain reaction. The differences of allelic frequency and genotype frequency distribution between patient and the control group were tested with Fisher-Freeman-Halton test. Results : There was association between DAT1 polymorphism and panic disorder(allele : p<0.03, genotype : p<0.05). The frequency of 10/10 homozygotes of DAT1 was significantly higher in control group(${\chi}^2$=4.452, df=1, p=0.035). Conclusion : These results in our Korean samples suggest that DAT1 polymorphism might be associated with the vulnerability of panic disorder. Possible association of dopaminergic genes and panic disorder should be investigated with future studies using larger and different population.

• Journal of Oriental Neuropsychiatry
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• v.16 no.1
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• pp.129-142
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• 2005

Objectives : This study was to investigate MMPI profile on clinical scales and personality scales of Panic Disorder patients. Methods : Thirty eight Panic Disorder patients and twenty eight normal control were administered the MMPI. Experimental design was done by nonequivalent control group and statistics were crosstabs, chi-square test, ANOVA, t-test and cluster analysis Results and Conclusions : 1. The MMPI clinical scales profile of Panic Disorder patients was neurotic profile of 2-7 type. Panic Disorder patients was elevated the other scales except L, K, Mf and Ma scales for control group. 2. A result of grouping MMPI in Panic Disorder patients, we could classify into 3 different groups. Group 1 is a profile of conversional neurosis. Group 2 is a normal proflie. Group 3 is a proflie of $'{\Lambda}'$ type neurosis. 3. Personality characteristics in Panic Disorder patients was lowed scores in HST, NAR scales, elevated the other scales except ANT scale. Specially in PAG, AVD scales showed high scores.

• Anxiety and mood
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• v.4 no.1
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• pp.28-33
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• 2008

Objective : A working group of psychiatrists from the Korean Academy of Anxiety Disorders was established to determine the appropriate medication algorithm for treating patients with panic disorder. In this article, we discussed the consensus among psychiatrists regarding the use of cognitive behavior therapy (CBT) in the development of a treatment algorithm for panic disorder in Korea. Methods : Based on the guidelines or algorithms published by the American Psychiatric Association, National Institute for Clinical Excellence, and Canadian Psychiatric Association, we constructed questionnaires regarding the core components and contents of CBT for patients with panic disorder. Fifty-four experts in panic disorder completed the questionnaires. Results : There was statistically significant consensus among the experts in the belief that cognitive reconstruction and psychological education are the core components of CBT for the treatment of patients with panic disorder. However, there was some inconsistency between the opinions of some experts regarding the content and frequency of CBT and the results of studies published outside of Korea. Conclusions : CBT, especially the psychological education and cognitive reconstruction components, should be considered when treating patients with panic disorder. However, further consideration needs to be put into the design of a more detailed treatment guideline for the use of CBT in the treatment of patients with panic disorder.

• 대한상한금궤의학회지
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• v.4 no.1
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• pp.1-12
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• 2012

Objective : The purpose of this study is to find out the effectiveness of Ling-Gui-Gan-Zao-Tang for patients of panic disorder. Method : To achieve the purpose of this study, Ling-Gui-Gan-Zao-Tang was prescribed for three months to two different patients of panic disorder. They were diagnosed as panic disorder in department of neuropsychiatry, and had no other prescribed decoction or psychotherapy. Results : 1. The BAI score for anxiety were decreased in both patients, and they got improved overall symptoms. 2. In panic attack, patients are in dominant state of sympathetic nerve, so they have palpitaion and get nervous. Fu-Ling(茯笭) can treate this kind of situation. 3. Based on and , urgent situation, over-tension of muscles, hot flash can be treated Gancao(甘草), Dazao(大棗), Guizhi(桂枝) respectively. Conclusions : When panic disorder attaks, the sympathetic nerves are dominant in patient's body. So they feel palpitating, sweating, suffocating. Ling-Gui-Gan-Zao-Tang can treat this series of symptoms.

• Korean Journal of Biological Psychiatry
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• v.16 no.1
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• pp.46-52
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• 2009

Objectives : The goal of this study was to compare the clinical characteristics of panic disorder respiratory subtype(PD-R) and non-respiratory subtype(PD-NR). Methods : 84 patients with panic disorder were enrolled and divided into 2 groups, 29 PD-R and 55 PD-NR. Diagnosis of panic disorder was evaluated using Diagnostic and Statistical Manual of Mental Disorders $4^{th}$ edition and Mini International Neuropsychiatric Interview. They were also measured with Hamilton Rating Scale for Anxiety(HAM-A), Hamilton Rating Scale for Depression(HAM-D), and Panic Disorder Severity Scale (PDSS). Results : PD-R group showed significantly higher scores in PDSS than those of PD-NR group(p=.027). After controlling for the severity of panic disorder and gender, PD-R group showed higher HAM-D and somatic anxiety subscale of HAM-A than those of PD-NR group. Furthermore, results of logistic regression analysis suggested that the somatic anxiety was a possible risk factor of PD-R(OR=1.404,p=0.009). Conclusion : These results suggest that somatic anxiety and depressive symptom would be important clinical characteristics of PD-R.

• International journal of advanced smart convergence
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• v.10 no.2
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• pp.21-30
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• 2021

With the rapid development of artificial intelligence and big data, a lot of medical data is effectively used, and the diagnosis and analysis of diseases has entered the era of intelligence. With the increasing public health awareness, ordinary citizens have also put forward new demands for panic disorder health services. Specifically, people hope to predict the risk of panic disorder as soon as possible and grasp their own condition without leaving home. Against this backdrop, the smart health industry comes into being. In the Internet age, a lot of panic disorder health data has been accumulated, such as diagnostic records, medical record information and electronic files. At the same time, various health monitoring devices emerge one after another, enabling the collection and storage of personal daily health information at any time. How to use the above data to provide people with convenient panic disorder self-assessment services and reduce the incidence of panic disorder in China has become an urgent problem to be solved. In order to solve this problem, this research applies the context awareness to the automatic diagnosis of human diseases. While helping patients find diseases early and get treatment timely, it can effectively assist doctors in making correct diagnosis of diseases and reduce the probability of misdiagnosis and missed diagnosis.