• 제목/요약/키워드: Panic Disorder

검색결과 150건 처리시간 0.026초

항우울제와 몽유병:Mirtazapine에 의한 증례 1례 (Antidepressant-Induced Somnambulism:A Case of Mirtazapine)

  • 정상근;오근영;조광현;황익근
    • 수면정신생리
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    • 제10권2호
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    • pp.113-115
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    • 2003
  • 몽유병은 수면수반증으로 분류되는데, 항우울제와 기타 향정신약물에 의해 이차적으로 유발될 수 있다는 보고들이 있었다. 그러나, NaSSA(noradrenergic and specific serotonergic antidepressant)계열인 mirtazapine에 의해 유발된 몽유병에 대한 보고가 없었다. 저자들은 우울증 환자에서 mirtazapine 사용에 의한 몽유병 1예를 경험하였기에 관련 문헌들을 고찰하고 보고하는 바이다.

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사암침법 간정격과 간승격의 최근 연구 동향 분석 (Recent Study Trends of the Liver-tonification and Liver-sedation of Saam Acupuncture)

  • 윤민지;김송이;박지연
    • Korean Journal of Acupuncture
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    • 제35권1호
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    • pp.1-17
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    • 2018
  • Objectives : This study was aimed to investigate current status researches and to provide source in setting development strategy on Liver-tonification acupuncture(LTA) and Liver-sedation acupuncture(LSA). Methods : We searched databases of Pubmed, KISS, OASIS, Google scholar and CNKI up to February 2017. We included articles that using LTA or LSA as main treatment, using the partial acupoints combination of LTA or LSA, or using each acupoint of LTA or LSA. We analyzed disease, details of acupuncture and control treatment and clinical outcomes from included studies. Results and Conclusions : Among the included clinical studies, case report was the most used methodology. LTA used to treat obesity, myopia, bartholinitis, tinnitus, hiccup and sleep disorder, prostate cancer and tremor. LSA used to treat panic disorder, gastroesophageal reflux disease and irritable bowl syndrome, herpes zoster and neuralgia. Obesity and tremor were the most studied diseases using LTA or LSA. Amyotrophic lateral sclerosis was the only disease which LTA or LSA have no therapeutic effect. Each acupoints was not used as a meaning of Saam acupuncture but as affiliated meridian acupoint. Since animal researches were not fully conducted, mechanism of LTA and LSA was hard to be proved. Thus, more clinical studies and basic animal research are needed.

불안 환자에 대한 불안척도의 연구 (A Study of Anxiety Scale Applied to Patients with Anxiety Disorder)

  • 이중훈;박병탁
    • Journal of Yeungnam Medical Science
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    • 제9권1호
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    • pp.156-166
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    • 1992
  • 1987년 1월 부터 1991년 6월 까지 영남대학교 영남의료원 정신과에 외래 및 입원한 정서장애 환자중 불안장애로 진단 받은 환자 남자 127명(77.3%), 여자 38명(23.0%)인 총 165명을 대상으로 하였다. 이들에게 Zung의 자가 평가 불안척도를 사용하여 불안을 측정한 결과는 다음과 같다. 불안성적의 평균 총점은 $42.40{\pm}7.74$을 보였다. 불안의 항목별 상위성적은 두통 및 신체동통, 피로, 불안, 공황, 빈뇨 등의 순서로 높았다. 항목별 하위성적은 초조, 우려, 호흡곤란, 발한, 불면 등의 항목이었다. SAS에서 심계항진과 공포, 심계항진과 진전, 피로와 혼돈, 졸도와 현기증, 공포와 불안, 악몽과 공포, 혼돈과 공황, 현기증과 혼돈, 심계항진과 공황, 피로와 두통 및 신체동통, 혼돈과 불안, 공황과 불안, 감각이상과 심계항진, 진전과 공포, 진전과 불안, 공황과 공포 등의 문항 간에는 확실히 상관이 있었다. 성적 분포는 50점 이상인 경우가 17.5%(29명)이였다. SAS에서 각 문항들의 신뢰도는 Cronbach 알파를 사용하여 검토한 결과 비교적 양호한 것으로 나타났다. SAS의 문항 전체의 신뢰도는 0.71로 나타났다.

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항불안제 사용의 임상지침 (Clinical Guidelines for Anti-anxiety Drug Use)

  • 임기영
    • 생물정신의학
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    • 제1권1호
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    • pp.31-39
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    • 1994
  • Anxiety and anxiety disorders are one of the most common and most serious psychiatric problems. Anti-anxiety drugs are one of the most effective treatment method for these problems. Benzodiazepines have various side-effects and the risk of overuse and abuse. Therefore, physicians should prescribe benzodiazepines carefully. However, they should not be discouraged from prescribing benzodiazepines when they have a knowledge of the pharmacological characteristics of these drugs and there is a clear indication for their use. Generally speaking, problems of benzodiazepine use such as dependence withdrawal symptoms, and cognitive impairment are more likely to occur with high dose, long-term use(more than 4 months), in geriatric patients and patients with a history of alcohol or other sustance abuse. But long-term or high-dose use can be jusified for patients with panic disorder of agoraphobia, and medically-ill patients with persistent anxiety that cannot be otherwise treated. In summary, there cannot be a general prescribing formulation for benzodiazepine use. Physician should always make their decision based on the individual patient's risk/benefit factors.

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감정표현불능증 : 그 개념과 치료적 함의 (Alexithymia : Concept and Implications for Treatment)

  • 함병주;김린
    • 수면정신생리
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    • 제9권1호
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    • pp.18-23
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    • 2002
  • Alexithymia represents deficits in the cognitive processing and regulation of emotions. It is observed in many cases of psychosomatic disease, anorexia nervosa, panic disorder, depression etc. Many studies have shown that alexithymia is associated with maladaptive styles of emotion regulation, low emotional intelligence, interhemispheric transfer deficit, and reduced rapid eye movement density. Psychotherapies that enhance emotional awareness may be effective in alleviating the difficulties of alexithymic individuals. Aexithymia is useful for constructing the role of personality and emotions in the pathogenesis of psychiatric disorders. It may serve as a bridge between neurobiology and psychology. We review recent alexithymia theory and research and their implications for treatment of psychosomatic disorders.

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대화 상태 추적 모델을 활용한 공황 장애 점진적 조기 위험 검출 시스템 (Incremental Early Risk Detection using Dialogue State Tracking for Panic Disorder)

  • 이채빈;이근배
    • 한국정보과학회 언어공학연구회:학술대회논문집(한글 및 한국어 정보처리)
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    • 한국정보과학회언어공학연구회 2022년도 제34회 한글 및 한국어 정보처리 학술대회
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    • pp.497-501
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    • 2022
  • 대화 상태 추적(Dialogue State Tracking)은 특정 목적을 달성하기 위한 대화 시스템인 목적 지향 대화 시스템의 핵심 부분으로, 대화에서 표현된 사용자의 목적을 추출한다. 조기 위험 검출 시스템은 연속적으로 들어오는 정보를 바탕으로 분류 대상인지 아닌지를 판별하며, 정확도 저하를 피하면서 최대한 빠르게 분류하는 것을 목표로 한다. 본 연구에서는 대화 상태 추적 시스템에서 나온 은닉층을 입력으로 하여 실시간으로 공황 장애 여부를 점진적으로 조기 분류하는 시스템과 조기 분류를 위한 새로운 손실 함수를 제안한다. 조기 위험 검출 시스템에 대화 상태인 belief state의 정보를 함께 사용했을 때, 큰 성능 향상을 보였으며 대화 상태가 조기 위험 검출에 필요한 정보를 담고 있음을 확인할 수 있다.

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공황장애 상담을 위한 멀티모달 과제 지향 대화 태스크 구축 (Building a multimodal task-oriented dialogue task for panic disorder counseling)

  • 김수빈;이근배
    • 한국정보과학회 언어공학연구회:학술대회논문집(한글 및 한국어 정보처리)
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    • 한국정보과학회언어공학연구회 2023년도 제35회 한글 및 한국어 정보처리 학술대회
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    • pp.258-262
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    • 2023
  • 과제 지향 대화 시스템은 발화 의도 및 요구사항을 파악하여 사용자가 원하는 과제를 달성한다는 점에서 유용하다. 대화 상태 추적은 과제 지향 대화 시스템의 핵심 모듈이며, 최근에는 텍스트뿐만 아니라 시각 정보까지 활용하여 대화 상태를 추적하는 멀티모달 대화 상태 추적 연구가 활발히 진행되는 중이다. 본 논문에서는 멀티모달 공황장애 상담 대화 속 내담자의 상태를 추적하는 과제를 제안하였다. ChatGPT를 통한 멀티모달 공황장애 상담 과제 지향 대화 데이터셋 구축 프레임워크와, 구축한 데이터셋의 품질을 증명하기 위한 분석도 함께 제시하였다. 사전학습 언어 모델인 GPT-2를 벤치마크 데이터셋에 대해 학습한 성능을 측정함으로써 향후 멀티모달 대화 추적 성능이 능가해야 할 베이스라인 성능을 제시하였다.

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소아(小兒) stress에 관한 문헌적(文獻的) 고찰(考察) (A study on stress in Children)

  • 김기봉;김장현
    • 대한한방소아과학회지
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    • 제16권1호
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    • pp.105-124
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    • 2002
  • With the progress of civilization, the disorders due to the stress, which derived from the social-structural complexity and diversity, are on an increasing trend in our times. Accordingly, the accurate diagnosis and appropriate treatment for them are required. Especially in the current years, children's disorders delivered by the emotional problems keep increasing. In this research, the researcher tried to figure out the cause of the children's stress and its treatment, studied the theories of the stress in the modem medicine and the sever emotions in oriental medicine, and came to the conclusion as follows: 1. The stress can be defined as the combination of the reaction to noxious stimuli and its defense mechanism of the body, In oriental medicine, it is considered as pathological notions which includes seven emotions as the internal factor, six evils as the external factor and other foods, expectoration, ecchymoma as the non-internal/external factors. 2. Children usually get stressed by various reasons in a growth process such as schooling, relationship with friends, the opposite sex of family, or change of surroundings, and these can cause the various disorders. 3. In the study of the children's stress symptoms, it is found that the silent reaction is uncommon. It usually appeared in both reactions: firs, physical reactions such as stomachache, vomiting, headache, neural frequent urination, bronchial asthma or excessive respiration and/or, second, behavioral reactions such as a decline of performance, alimentary disorder, e.g. anorexia nervosa or bulimia, sleep disorder, e.g. nightmare or panic in sleep, anthrophobia, refusal to a school attendance or hyperactiveness. Besides, the peculiar mental disorder such as paroxysm of anger, tic, autism, nocturnal enuresis, lack of attentiveness, impediment in linguistic development, learning difficulty, intellectual decline, etc. can be appeared, and the heavy stress during the babyhood can cause the regression of behavior or the immaturity of formation of character. 4. The appropriate treatments for the children's stress are Osteopathy, Manpulation, Aroma Therapy, Alexander Technique, Autonomic Never Control Treatment, Biofeedback, Chiropractic, Dance Therapy, Feldenkrasis Technique, Gravity Therapy, Homepathy, Aquatherapy, Hypnotherapy, Naturopathy and Meditation.

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향정신성 약물 중독에 의한 QTc 연장과 그 위험성에 대한 고찰 (QTc Prolongation due to Psychotropic Drugs Intoxication and Its Risk Assessment)

  • 박관호;홍훈표;이종석;정기영;고석훈;김성규;최한성
    • 대한임상독성학회지
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    • 제18권2호
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    • pp.66-77
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    • 2020
  • Purpose: The aims of the present study were twofold. First, the research investigated the effect of an individual's risk factors and the prevalence of psychotropic drugs on QTc prolongation, TdP (torsades de pointes), and death. Second, the study compared the risk scoring systems (the Mayo Pro-QT risk score and the Tisadale risk score) on QTc prolongation. Methods: The medical records of intoxicated patients who visited the emergency department between March 2010 and February 2019 were reviewed retrospectively. Among 733 patients, the present study included 426 psychotropic drug-intoxicated patients. The patients were categorized according to the QTc value. The known risk factors of QTc prolongation were examined, and the Mayo Pro-QT risk score and the Tisadale risk score were calculated. The analysis was performed using multiple logistic regression, Spearman correlation, and ROC (receiver operating characteristic). Results: The numbers in the mild to moderate group (male: 470≤QTc<500 ms, female: 480≤QTc<500 ms) and severe group (QTc≥500 ms or increase of QTc at least 60ms from baseline, both sex) were 68 and 95, respectively. TdP did not occur, and the only cause of death was aspiration pneumonia. The statically significant risk factors were multidrug intoxications of TCA (tricyclic antidepressant), atypical antipsychotics, an atypical antidepressant, panic disorder, and hypokalemia. The Tisadale risk score was larger than the Mayo Pro-QT risk score. Conclusion: Multiple psychotropic drugs intoxication (TCA, an atypical antidepressant, and atypical antipsychotics), panic disorder, and hypokalemia have been proven to be the main risk factors of QTc prolongation, which require enhanced attention. The present study showed that the Tisadale score had a stronger correlation and predictive accuracy for QTc prolongation than the Mayo Pro-QT score. As a result, the Tisadale risk score is a crucial assessment tool for psychotropic drug-intoxicated patients in a clinical setting.

세로자트정(파록세틴 20 mg)에 대한 삼천리파록세틴정의 생물학적동등성 (Bioequivalence of Paroxetine Tablet to Seroxat Tablet (Paroxetine 20 mg))

  • 고인자;지상철
    • Journal of Pharmaceutical Investigation
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    • 제34권6호
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    • pp.499-504
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    • 2004
  • Paroxetine, a potent and selective serotonine reuptake inhibitor, has been used for the treatment of depression, obsessive-compulsive disorder, panic disorder and social phobia. The bioequivalence of two paroxetine preparations was evaluated according to the guidelines of Korea Food & Drug Administration (KFDA). The test product was Samchully Paroxetine $tablet^{\circledR}$ made by Samchully Pharm. Co. and the reference product was Seroxat $tablet^{\circledR}$ made by GlaxoSmithKline. Twenty healthy male subjects, $22.4{\pm}2.6$ years old and $63.8{\pm}4.2\;kg$, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After one tablet containing 20 mg paroxetine was orally administered, blood was taken at predetermined time intervals and the concentration of paroxetine in plasma was determined using a validated HPLC method with fluorescence detector. Two pharmacokinetic parameters, $AUC_t$ and $C_{max}$, were calculated and analyzed statistically for the evaluation of bioequivalence of two products. Analysis of variance was carried out using logarithmically transformed parameter values. The 90% confidence intervals of $AUC_t$ and $C_{max}$ were log 0.84-log 1.16 and log 0.85-log 1.14, respectively. These values were within the acceptable bioequivalence intervals of log 0.8 to log 1.25. Thus, the criteria of the KFDA guidelines for the bioequivalence was satisfied, indicating that Samchully Paroxetine tablet is bioequivalent to Seroxat tablet.