• 한국동물위생학회지
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• 제46권1호
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• pp.93-106
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• 2023

Emerging and re-emerging zoonotic viruses become critical public health, economic, societal, and cultural burdens. The Coronavirus disease-19 (COVID-19) pandemic reveals needs for effective preparedness and responsiveness against the emergence of variants and the next virus outbreak. The targeted next-generation sequencing (NGS) significantly contributes to the acquisition of viral genome sequences directly from clinical specimens. Using this advanced NGS technology, the genomic epidemiology and surveillance play a critical role in identifying of infectious source and origin, tracking of transmission chains and virus evolution, and characterizing the virulence and developing of vaccines during the outbreak. In this review, we highlight the platforms and preparation of targeted NGS for the viral genomics. We also demonstrate the application of this strategy to take advantage of the responsiveness and prevention of emerging zoonotic viruses. This article provides broad and deep insights into the preparedness and responsiveness for the next zoonotic virus outbreak.

• 치위생과학회지
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• 제22권1호
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• pp.51-56
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• 2022

Background: The coronavirus disease (COVID-19) pandemic increased awareness regarding the importance of hand hygiene in infection prevention. Although social distancing and vaccination are the strongest ways to prevent infection, personal hand hygiene is the most basic and easiest way to maintain public health. However, in addition to hand washing using running water, sanitizing tissues, and disinfection products are convenient for hand hygiene, especially outdoors. Therefore, it is necessary to improve the appropriateness of individual hand hygiene methods. In this study, we investigated the degree of hand hygiene offered by various hygiene products and hand drying methods for maintaining hand hygiene. Methods: An LED UV light kit was used for fluorescent observation of hand contamination. Bacteria from the hands were cultured to compare the degree of hand hygiene offered by various hygiene products. Bacteria were cultured in a hand-shaped medium dish to identify areas vulnerable to hand hygiene. Moreover, the degree of hand hygiene was observed according to the drying method using bacterial cultures. Results: We confirmed that hand washing under running water with antibacterial soap, sanitizing with alcohol gel disinfectant, and wiping with antibacterial wet wipes was effective for hand hygiene compared to washing under running water alone. However, for all hygiene products, a large number of bacteria were detected on the fingertips. We verified that natural drying, rather than rubbing, is effective in maintaining hand hygiene. Conclusion: These results suggest that hand hygiene products and drying methods are critical in hand hygiene management. Therefore, these results provide a basis for determining whether an individual's hand hygiene management method is appropriate.

• Journal of Ginseng Research
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• 제47권6호
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• pp.687-693
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• 2023

Due to the Covid-19 pandemic more than 6 million people have died, and it has bought unprecedented challenges to our lives. The recent outbreak of monkeypox virus (MPXV) has brought out new tensions among the scientific community. Currently, there is no specific treatment protocol for MPXV. Several antivirals, vaccinia immune globulin (VIG) and smallpox vaccines have been used to treat MPXV. Ginseng, one of the more famous among traditional medicines, has been used for infectious disease for thousands of years. It has shown promising antiviral effects. Ginseng could be used as a potential adaptogenic agent to help prevent infection by MPXV along with other drugs and vaccines. In this mini review, we explore the possible use of ginseng in MPXV prevention based on its antiviral activity.

• Asia pacific journal of information systems
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• 제34권1호
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• pp.91-113
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• 2024

In the wake of the COVID-19 pandemic, unsubstantiated information concerning vaccines and the coronavirus has proliferated on various social media platforms. Consequently, we have considered viable actions to mitigate the impact of such unverified content, enabling individuals to use social media platforms more effectively and minimize any ensuing confusion. Recent measures in this area have included YouTube's practice of labeling vaccine or corona videos as authoritative when emanating from reputable organizations and Twitter's practice of flagging vaccine-related content as potentially misleading or taken out of context. This study seeks to explore how such contrasting labeling practices influence users' believability and engagement differentially, while also examining the moderating impact of regulatory focus. The results indicate that authoritative labeling positively influenced users' believability and engagement, whereas misleading labeling adversely affected users' believability and engagement. Additionally, our findings revealed that authoritative labeling has a stronger impact on promotion-focused individuals, while misleading labeling has a more pronounced effect on prevention-focused individuals. Our findings offer insights into how social media platforms can design and present information to their users, taking into account their regulatory focus.

• 식품보건융합연구
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• 제10권3호
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• pp.1-8
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• 2024

The global nutraceuticals market continues to grow due to rising income levels, increasing life expectancy, and a growing interest in personal health. Especially after the COVID-19 pandemic, the market for nutraceuticals has expanded rapidly with positive perceptions driven by increased attention to immune management for disease prevention. However, there is still a lack of research on the relationship between nutraceuticals and consumer behavior. This study aims to provide new insights into the dietary supplement market and help establish marketing strategies by analyzing consumer behavior toward dietary supplements in the post-COVID-19 era, focusing on Generation MZ. An online survey was conducted among consumers who have purchased dietary supplement products to test the hypotheses. The collected data were analyzed for validity and reliability using SPSS and AMOS programs. The results showed that the taste, price, brand, and design of dietary supplements significantly positively affect the satisfaction of MZ consumers. This study provides an in-depth understanding of the mechanisms of consumer behavior toward dietary supplements in the post-COVID-19 era, focusing on Generation MZ. By offering insights into consumers' health concerns and consumption behaviors, this study provides valuable perspectives on the future development of the market and helps companies develop effective strategies to meet consumer needs.

• 산경연구논집
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• 제15권5호
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• pp.17-27
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• 2024

Purpose: The renminbi (RMB) has appreciated alongside the elevation of China's economic status, leading to increased exchange rate volatility. Moreover, China's medical industry saw a surge in import and export trade volume, with trade related to epidemic prevention and control in the medical sector significantly increasing its share. The medical device trade, in particular, occupies a substantial portion of this trade. Research design, data and methodology: This paper focuses on the import and export value of medical devices in the medical industry as a case study to explore the impact of RMB exchange rate fluctuations on the import and export trade of the medical industry during the pandemic. Additionally, it investigates whether the import and export trade of the medical industry can be a contributing factor to the fluctuations in the RMB exchange rate. Results: Through an empirical study on the import and export values of medical devices in the medical industry over the past three years, as well as the RMB exchange rate, this paper establishes a VAR model and conducts a series of tests including stationarity tests and cointegration tests. Conclusions: The conclusion is that fluctuations in the RMB exchange rate have a long-term impact on China's medical industry's import and export trade.

• Korean Circulation Journal
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• 제52권11호
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• pp.808-813
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• 2022

Studies showing that coronavirus disease 2019 (COVID-19) is associated with an increased risk of cardiovascular disease continue to be published. However, studies on how long the overall cardiovascular risk increases after COVID-19 and the magnitude of its long-term effects have only been confirmed recently. This is partly because the distinction between cardiovascular risk as an acute complication of COVID-19 or post-acute cardiovascular manifestations is ambiguous. Long-COVID has arisen as an important topic in the second half of the pandemic. This term indicates that symptoms persist for more than two 2 months; following three months of SARS-CoV-2 infection and cannot be explained by other medical conditions. Despite the agreement of these international organizations and experts, it is difficult to define whether there is sufficient medical evidence to prove the existence of long-COVID. However, the Korean government and Korea Disease Control and Prevention Agency (KDCA) are preparing a new platform to assess the long-term impact of COVID-19. Using this data, a prospective cohort of 10,000 confirmed COVID-19 cases will be established. This cohort will be linked with claims data from the National Health Insurance Services (NHIS) and it is expected that increased real-world evidence of long-COVID will be accumulated.

• 생명과학회지
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• 제31권6호
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• pp.603-608
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• 2021

본 연구는 COVID-19과 COVID-19 변이 바이러스 시기에 vaccination을 통한 집단면역달성을 목표로 하고 있지만, 백신의 종류에 따라서 다양한 부작용도 발생을 하여, 백신 이외에 평소 규칙적인 운동을 통한 백신 효과의 조그만 근거를 마련하고자 수행하게 되었다. 이러한 연구 연구목적을 달성하기 위해 본론에서는 COVID-19 vaccine의 이슈, COVID-19 블루, COVID-19과 스포츠이벤트, 및 COVID-19과 운동중재에 관해 분석하였다. 본 연구결과 COVID-19은 혈관을 우선적으로 공격하고 혈관 내막에 침투해 혈액순환을 방해하는 바이러스로 알려져 있다. 그리고 이어서 폐, 심장, 뇌 등을 공격한다. 심혈관 질환이 있는 환자들은 몸에서 바이러스를 몰아내는 능력이 떨어져 있는 이유로 이러한 바이러스의 공격대상이 될 수 있다. 혈관은 적혈구와 영양소만 이동하는 곳이 아니라 백혈구와 림프구들도 이동하므로 평소 불포화 지방산, 저탄수화물 식이요법을 포함하는 건강한 식이 습관, 금연, 일상생활도의 증가 및 규칙적인 운동 습관의 중요성이 중요하게 고려되어 진다. 이러한 관점에서 평소 혈관의 건강은 매우 중요하게 작용하고 이는 규칙적인 운동을 통하여 얻을 수 있는 것이다. 규칙적인 운동은 면역세포들, 면역글로불린, 다양한 사이토카인들의 순환을 돕고 특히, 폐로의 순환을 도와 염증인자들을 감소시키는 역할을 수행하고 병원균의 유입을 막아주는 역할을 한다. 특히, 혈관 내막에 침투해 혈액순환을 방해하는 것으로 알려져 있으며 폐, 심장, 뇌 등을 공격하는 COVID-19의 특성을 고려할 때 운동을 통한 건강관리는 바이러스 예방에 필수적이라고 할 수 있다. 현재 다양하고도 많은 백신의 사용은 팬데믹 시기에서 매우 희망적이지만 아나플락시스나 혈전 색전증 등의 다양한 부작용도 초래하므로 규칙적인 운동중재는 백신의 도움없이 세균이나 바이러스로부터 나를 지키는 면역력을 잘 유지하게 하는 것이 규칙적인 운동이 되는 것이다. 추후 이러한 분야에 관한 심도 있는 연구들이 수행되어져야 할 것으로 여겨진다.

• 서비스연구
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• 제13권2호
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• pp.146-160
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• 2023

코로나 19로 인하여 비대면 서비스가 확산되면서 소비자의 구매행동에는 많은 변화가 일어나고, 여러 새로운 서비스도 주목받고 있다. 이렇게 갑작스레 변화된 환경으로 새로운 서비스를 경험하는 시도가 소비자의 기존 선택 행동의 형태를 변화시킬 수도 있을까? 특히 변화를 두려워하고 기존의 선택 경향을 고수하려는 소비자의 행동까지도 변화시킬 수 있다면 혁신 서비스 개발은 예상보다 더 많은 잠재 소비자를 획득할 수 있게 될 것이다. 이에 본 연구는 팬데믹 이후 나타난 언택트 서비스 중 하나인 무인 결제 서비스를 대상으로 혁신 서비스 이용 시도가 위험회피 성향을 가진 소비자의 기존 선택 행동에 변화, 즉 안전대안보다 위험대안을 선호할 가능성을 높이는지 살펴보고자 하였다. 탐색조사 결과에 따르면, 평소 위험회피 성향이 강할수록 혁신 서비스 사용에 대한 자기효능감은 낮아지는 부(-)의 관계가 나타났다. 이러한 조사 결과를 바탕으로 연구는 실험법을 사용하여 혁신 서비스 이용 여부와 소비자의 조절초점 간 상호작용과 심리적 기제를 함께 살펴보고자 하였다. 분석 결과에 따르면, 예방초점 소비자는 무인 결제 서비스 이용을 시도하는 조건에서 이용하지 않은 조건에 비하여 고위험 금융상품과 비유사 확장 브랜드에 대한 높은 선택가능성을 보였다. 이에 반하여 향상초점 소비자는 무인 결제 서비스 이용 시도 여부에 따른 차별된 선택 가능성을 보이지 않았다. 나아가 예방초점 소비자에게 나타난 이러한 선택 변화는 혁신 서비스에 대한 자기효능감이 심리적 기제로 작동하고 있음이 확인되었다. 본 연구는 새로운 행동을 시도하는데 주저함이 많다고 알려진 위험회피 성향의 소비자의 행동 변화 조건을 밝혀 혁신 서비스의 잠재적 소비자층을 발견하고, 관련 시장의 확장 가능성을 보여주었다는 점에서 실무 및 학문적 시사점을 제안하였다.

• Journal of Microbiology and Biotechnology
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• 제20권10호
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• pp.1450-1456
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• 2010

Accurate and rapid diagnosis of Pandemic Influenza A/H1N1 2009 virus (H1N1 2009) infection is important for the prevention and control of influenza epidemics and the timely initiation of antiviral treatment. This study was conducted to evaluate the performance of several diagnostic tools for the detection of H1N1 2009. Flocked nasopharyngeal swabs were collected from 254 outpatients of suspected H1N1 2009 during October 2009. This study analyzed the performances of the RealTime Ready Inf A/H1N1 Detection Set (Roche), Influenza A (H1N1) Real-Time Detection Kit (Bionote), Seeplex Influenza A/B OneStep Typing Set [Seeplex Reverse Transcriptase PCR (RT-PCR)], BinaxNow Influenza A & B Test Kit [Binax Rapid Antigen Test (RAT)], and SD BIOLINE Influenza Ag kit (SD RAT). Roche and Bionote real-time RT-PCR showed identical results for the H1N1 2009 hemagglutinin gene. Compared with real-time RT-PCR, the sensitivities and specificities were 83.7% and 100% for Seeplex RT-PCR, 64.5% and 94.7% for Binax RAT, and 69.5% and 100% for SD RAT. The sensitivities of Seeplex RT-PCR, Binax RAT, and SD RAT in patients aged over 21 years were 73.7%, 47.4%, and 57.9%, respectively. The sensitivities of Seeplex RT-PCR, Binax RAT, and SD RAT on the day of initial symptoms were mostly lower (68.8%, 56.3%, and 31.3%, respectively). In conclusion, multiplex RT-PCR and RAT for the detection of H1N1 2009 were significantly less sensitive than real-time RT-PCR. Moreover, a negative RAT may require more sensitive confirmatory assays, because it cannot be ruled out from influenza infection.