• Title/Summary/Keyword: Panax ginseng meyer

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The Effect of Saponin Fraction of Panax ginseng C.A.Meyer on the Biosynthesis of Androgens in Rat Testis (인삼 사포닌이 쥐의 정소에서의 Androgen 생합성에 미치는 영향)

  • 홍성렬;주충노
    • Journal of Ginseng Research
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    • v.9 no.2
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    • pp.213-220
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    • 1985

  • It was attempted to observe the effects of ginseng saponin, one of the major components of the roots of Panax ginseng, on androgen biosynthesis from cholesterol in vitro as well as in vivo in rat testis. Ginseng saponin was administered by stomach tubing prior to intraperitoneal injection of cholesterol containing (4-14C)-cholesteroll into adult male rats and the liver, testis and blood serum were analyzed. The first high radioactivity of the liver and blood serum of test animal was observed at 6 hours after radioactive cholesterol injection, while that of control appeared at 12 hours after the injection. In the case of testis, the first high radioactivity of test group appeared between 4 and 6 hours after the radioactive cholesterol injection, while that of control appeared at 10-14 hours. Analysis of radioactivity distribution of cholesterol, androstenedione and testosterone in the testis of rats fed with/without ginseng saponin piror to (4-14C)-cholesterol injection showed that the saponin stmulated the synthesis of androgens from cholesterol. This was confirmed again by in vitro experiment using testis homogenate as an enzyme source. From the above experimental results, it was suggested that the ginseng saponin stimulates both cholesterol transport and the biosynthesis of androgens from cholesterol in rat testis.

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Genetic Diversity and Genetic Structures in Ginseng Landraces (Cultivars) by SRAP Analysis (SRAP 분석에 의한 중국 재배삼의 유전적 다양성)

  • Xu, Young Hua;Jin, Hui;Kim, Young-Chang;Bang, Kyong-Hwan;Cha, Seon-Woo;Zhang, Lian Xue
    • Korean Journal of Medicinal Crop Science
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    • v.18 no.3
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    • pp.180-185
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    • 2010

  • We investigated genetic diversity among and within the populations of cultivated ginseng (Panax ginseng C. A. Meyer ) using SRAP profiles. A total of 24 ginseng plants were sampled from the three populations (two from China, one from Korea). Since all these populations are previously shown closely related to each other assister groups, we used Panax quinquefolium L. and wild ginseng as a reference species, which is not "within the sister group". All individuals from the three populations were screened with a total of 36 primer pairs with 26 primers generated from 328 SRAP bands of DNA gels. The mean gene diversity ($H_E$) was estimated to be 0.057 within populations (range 0.032-0.067), and 0.086 at the species level. The genetic differentiation (Gst=0.31) indicates that genetic variation apportioned 30% among populations and 70% within populations. Generally, the result of this study indicates that ginseng contains high molecular variation in its populations.

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Red ginseng (Panax ginseng Meyer) oil: A comprehensive review of extraction technologies, chemical composition, health benefits, molecular mechanisms, and safety

  • Truong, Van-Long;Jeong, Woo-Sik
    • Journal of Ginseng Research
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    • v.46 no.2
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    • pp.214-224
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    • 2022

  • Red ginseng oil (RGO), rather than the conventional aqueous extract of red ginseng, has been receiving much attention due to accumulating evidence of its functional and pharmacological potential. In this review, we describe the key extraction technologies, chemical composition, potential health benefits, and safety of RGO. This review emphasizes the proposed molecular mechanisms by which RGO is involved in various bioactivities. RGO is mainly produced using organic solvents or supercritical fluid extraction, with the choice of method greatly affecting the yield and quality of the end products. RGO contains a high unsaturated fatty acid levels along with considerable amounts of lipophilic components such as phytosterols, tocopherols, and polyacetylenes. The beneficial health properties of RGO include cellular defense, antioxidation, anti-inflammation, anti-apoptosis, chemoprevention, hair growth promotion, and skin health improvement. We propose several molecular mechanisms and signaling pathways that underlie the bioactivity of RGO. In addition, RGO is regarded as safe and nontoxic. Further studies on RGO must focus on a deeper understanding of the underlying molecular mechanisms, composition-functionality relationship, and verification of the bioactivities of RGO in clinical models. This review may provide useful information in the development of RGO-based products in nutraceuticals, functional foods, and functional cosmetics.

  • https://doi.org/10.1016/j.jgr.2021.12.006 인용 PDF KSCI