• Journal of Korean Neurosurgical Society
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• 제41권1호
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• pp.27-29
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• 2007

Objective : Surgical treatment of focal plantar hyperhidrosis is often unsatisfactory compared to palmar hyperhidrosis. The purpose of this study is to evaluate the effect of lumbar sympathetic radiofrequency neurotomy on plantar hyperhidrosis. Methods : From February 2004 to December 2005, 10 patients [mean age 24.3 male 1, female 9] with the clinical diagnosis of plantar hyperhidrosis were treated by bilateral lumbar sympathetic radiofrequency neurotomy of L3 and L4. Patients' symptom relief, satisfactory rate and side effects related to the procedure were analyzed. Results : Radiofrequency neurotomy was effective in the treatment of focal plantar hyperhidrosis showing excellent [more than 75% improved] outcome in 70% of the patients and good [more than 50% improved] in 30%. Complications related to the surgical procedure, such as sensory dysesthesia and compensatory hyperhidrosis were not detected in any case. Conclusion : The use of radiofrequency neurotomy to ablate the lumbar sympathetic ganglion is a safe and effective treatment option for patients with plantar hyperhidrosis.

• Journal of Korean Neurosurgical Society
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• 제37권5호
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• pp.354-356
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• 2005

Objective: Thoracoscopic sympathicotomy is effective in treating not only palmar hyperhidrosis, but also axillary hyperhidrosis. But studies for axillary hyperhidrosis accompanying osmidrosis are few. We report the outcome of six axillary hyperhidrosis with osmidrosis with literatures review. Methods: Using a minimally invasive technique, thoracoscopic T3-4 sympathicotomy was performed. The results of sympathicotomy of third and fourth sympathetic chains of six patients from January 1999 to August 2003 for axillary hyperhidrosis with osmidrosis were reviewed. Results: All patients had a successful outcomes, their profuse sweating ceased. Two patients suffered from compensatory hyperhidrosis. Three patients disappeared or diminished foul odor but three patients complained remained osmidrosis. Conclusion: In the treatment of axillary hyperhidrosis, the sympathicotomy of T3 and T4 chain is an effective method but osmidrosis must be treated according to its cause.

• Journal of Korean Neurosurgical Society
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• 제29권11호
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• pp.1499-1504
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• 2000

Objectives : In general, conventional T2, T3 thoracoscopic sympathicotomy must be one of the most effective treatments for the essential palmar hyperhidrosis. However, this is offset by the occurrence of a high rate of side effects, such as embarrassing compensatory sweating and Hornor's syndrome. The authors have performed a selective T3 thoracoscopic sympathicotomy to our patients to see whether it provides successful results with less side effects. Its preliminary results were compared with those of conventional T2, T3 thoracoscopic sympathicotomy. Methods : The thoracoscopic sympathicotomy was performed in 54 patients suffering from essential palmar hyperhidrosis. Twenty-four patients underwent a conventional sympathicotmy(group A) from Jan 1997 to Dec 1997 and 30 patients a selective T3 sympathicotmy(group B) from Jan 1998 to Dec 1999. For assessment of postoperative success and of complications all patients charts were reviewed. Patients further received a postal questionnaire regarding long-term effect, satisfaction, and side-effects. Results : No recurrence was observed in both groups. The global rate of compensatory sweating was significantly(p ＝0.020) different in both groups : 11 patients(45.8%) in group A and 5 patients(16.73%) in group B. The Hornor's syndrome was observed only in 4 patients in group A. The preliminary results of the procedure in group A were considered fully-satisfying by 16 patients(66.6%), 6 patients(25%) were satisfied partially, and only 2 patients(8.3%) were dissatisfied, and those of the procedure in group B satisfying by 26 patients(86.6%), 4 patients(13.3.% ) were satisfied partially, and none dissatisfied. Conclusion : The selective T3 sympathicotomy results in a significant decrease in the rate of disturbing side effects comparing to conventional T2, T3 sympathicotomy and it dose not lead to recurrence. Our results contribute to recommendations of a selective T3 thoracoscopic sympathicotomy as treatment of choice in essential palmar hyperhidrosis.

• The Korean Journal of Pain
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• 제22권3호
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• pp.253-256
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• 2009

Conventional thoracoscopic sympathectomy is an effective method in treating palmar-axillary hyperhidrosis. However, this may result in a postoperatively compensatory hyperhidrosis. Conservative treatments of compensatory hyperhidrosis consist of aluminum chloride, anticholinergics, iontrophoresis, and botulinum toxin A injections. Surgical treatments in compensatory hyperhidrosis include excision of axillary tissue, liposuction, and thoracoscopic sympathectomy. Intradermal injection of botulinum toxin A has used to treat focal axillary or palmar hyperhidrosis. Botulinum toxin A bestows significant benefits with few side-effects and is well-tolerated, with beneficial results lasting from 4-16 months. We report a case illustrating the beneficial use of botulinum toxin A in a 25-year-old healthy male patient with compensatory sweating of the flank after thoracoscopic sympathectomy. Modified Minor's starch iodine test was used to allow accurate assess the impact of hyperhidrosis on the patient. In conclusion, Botulinum toxin type A is a valuable therapy for compensatory sweating after endoscopic thoracic sympathectomy.

• Journal of Chest Surgery
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• 제33권11호
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• pp.904-905
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• 2000

28세 남자가 4년전 수장부 다한증으로 양측 제 2, 제3흉부교감신경절제술을 받고 난 후 우측 손에 한냉증이 발생하였다. 흉부교감신경절제술 후 발생한 수부 한냉증은 매우 드문 현상이다. 이 증례를 문헌 고찰과 함께 보고하는 바이다.

• 대한한의학회지
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• 제33권4호
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• pp.37-41
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• 2012

Objectives: This study was aimed to establish the clinical features of the patients suffering from hyperhidrosis, who are willing to visit Oriental clinics. Methods: Forty-six patients with primary hyperhidrosis were enrolled in this study classification, body part of perspiration and its severity, and constitutional differentiation were analyzed. Results: 85.1% of patients were 10 to 39 years old. The body part most complained of hyperhidrosis was the hands and feet at 50%. The portion of Teaeumin, Soumin, and Soyangin was 56.6% 21.1%, and 21.7% respectively. Soumin specifically showed a higher frequency of palmar and plantar hyperhidrosis as 90%. The average score of symptoms was $5.1{\pm}1.7$ by a 10-point self- reporting numeric rating scale (NRS). No statistical difference of NRS score was observed regarding gender, Sasang classification, or hyperhidrosis region. Conclusions: This study provides an overview of hyperhidrosis patients visiting an Oriental clinic, and will be helpful in establishing a strategy for the Korean medicine (KM)-based therapeutic development.

• Journal of Chest Surgery
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• 제37권6호
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• pp.530-535
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• 2004

배경: 수부 다한증을 치료하기 위해 시행하는 제3번 늑골 위 교감신경 차단술의 경우 다한증 치료 효과는 교감신경 절제술과 유사하면서 보상성 다한증의 발생이 교감신경절제술보다 적다는 연구결과들이 많이 있으나 대부분 단기 결과이며 중기 추적 결과가 발표되어 있지 않아 제3번 늑골 위 교감신경 차단술의 중기 추적을 시행하였다. 대상 및 방법: 인하대학병원 흉부외과에서 99년 4월부터 2001년 8월까지 제3번 늑골 위 교감신경 차단술을 시행한 환자 94명 중 설문조사가 가능했던 76명(남자 38명, 여자 38명)을 대상으로 전화 설문을 시행하여 평균 25$\pm$9.1개월 간(15∼50개월)의 중기 결과를 추적하였다. 교감신경은 3번째 늑골 상방에서 절단하였다. 환자들의 만족도를 알기 위하여 linear analogue scale을 사용하였다 (100: 가장 만족함). 결과: 수술 후 만족도에 관한 질문에서 100점 만점 기준일 때 수술 직후 만족도가 92.36$\pm$9.93 인데 비해 수술 후 15개월에는 7l.80$\pm$20.24로 만족도가 감소하였으며(p<0.001) 이러한 만족도 감소의 이유는 보상성 다한증과 증상 재발 때문이었다. 땀나는 정도도 수술 직후 중앙값 0에서 15개월 후 중앙값 1.5로 증가하였다. 보상성 다한증의 경우 수술 직후 중앙값 1에서 수술 15개월 후 5로 증가하였다. 결론: 이와 같은 결과로 제3번 늑골 위 교감 신경 차단술의 경우 수술 직후에는 훌륭한 치료 효과를 보이나 수술 15개월 후에는 치료효과가 점차 감소한다. 불만족의 가장 흔한 이유는 보상성 다한증과 다한증의 재발이다.

• Journal of Chest Surgery
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• 제32권5호
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• pp.461-464
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• 1999

배경: 흉강경을 이용한 T2 교감신경절단술은 수장부다한증의 효과적인 치료법이다. 교감신경을 절단하면 다한증 증상이 소실되는 것은 물론 피하혈관의 확장으로 동측 손바닥 온도가 올라간다. 그러나 반대측 손바닥의 온도 변화에 대해서는 밝혀진 바가 적다. 저자들은 수장부다한증 환자에서 교감신경절단술 과정에 나타나는 양측 손바닥 온도의 변화양상을 알아보고자 하였다. 대상 및 방법: 일차성 수장부다한증 환자 15명에서 T2 교감신경절단술을 시행하였다. 수술중 양측 손바닥에 피부온도감지패취를 부착하여 손바닥의 온도를 관찰기록하였다. 결과: 먼저 좌측 2번 흉부교감신경을 절단하자 동측 손바닥의 온도는 상승하고 반대측 손바닥의 온도는 감소하였다. 두 손바닥의 온도차는 우측 교감신경절단전에 가장 컸으며(좌측 34.6$\pm$0.9 $^{\circ}C$, 우측 31.6$\pm$1.3$^{\circ}C$, P < 0.0001) 반대쪽(우측) 교감신경을 절단하자 감소하였던 우측 손바닥의 온도가 상승하여 수술종료시 두 손바닥의 온도차가 없어졌다(좌측 34.7$\pm$1.0 $^{\circ}C$, 우측 34.4$\pm$1.0 $^{\circ}C$, P=0.415). 결론: 수장부 다한증에서 교감신경절단술을 시행할 때는 상지에 분포하는 교감신경이 정확히 차단되었는가를 확인하는 것이 중요하다. 이를 위해서 수술중 손바닥 피부온도를 측정하여 온도상승을 확인한다. 반대측 손바닥 온도가 감소하는 기전인 혈관수축에는 교차억제효과(Cross inhibitory effect)가 관계될 것으로 생각되며 향후 이에 대한 많은 연구가 이루어져야 할 것으로 생각된다.

• Annals of Clinical Neurophysiology
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• 제14권1호
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• pp.12-19
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• 2012

Thermoregulatory sweat is principal mean for homeostasis of temperature. Sweat glands have eccrine gland, apocrine gland, and apoeccrine glands. Disorders of sweating are manifested by excess (hyperhidrosis) or deficit (hypohidrosis, anhidrosis) of sweat. Hyperhidrosis can be defined as excessive sweating beyond a level required to maintain normal body temperature. The sweating can be generalized or localized (axilla, palms, soles, palmar-plantar, perineal). Usually hypohidrosis or anhidrosis may be more serious than hyperhidrosis. Hyperhidrosis is usually benign, but interferes with one's daily activities. First step for diagnostic approach for sweating disorders might be dividing them into localized or generalized, and primary or secondary forms. Treatement for hyperhidrosis include topical agents, botulinum toxin A injections, systemic anticholinergics, and sympathectomy.

• Journal of Chest Surgery
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• 제28권7호
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• pp.684-688
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• 1995

Hyperhidrosis, one of the abnormalities in autonomic nervous system, has been treated with dermatologic principles or thoracic sympathectomy via conventional axillary thoracotomy or dorsal spinal approach. But these techniques were rather ineffective or invasive. Recently, VATS is widely applied in thoracic surgical area, and hyperhidrosis is not the exception of these cases.From May 1993 to August 1994, 30 patients with bilateral palmar hyperhidrosis underwent bilateral thoracic [T2, T3 sympathectomy with thoracoscopic surgery at Seoul National University Hospital. There were 20 men and 10 women and the mean age was 23.0 years.Mean operating time was 115 min and there was no thoracotomy conversion. Operative complications were anesthetic overdose in 1, Horner`s syndrome in 1, and small amount of residual pneumothorax in 6. Mean postoperative hospital stay was 2.3 days [range from 1 to 4 days and postoperative analgesics were required in 17 cases with a single dose.Sweating amount was measured in 12 patients, showing significantly decreased amount from 284.5 mg preoperatively to 18.9 mg postoperatively in 5 minutes [p=0.004 . There was no recurrence during mean 6 months follow up. Twenty two patients [73.3 % complained moderate compensatory hyperhidrosis on the trunk.In conclusion, all patients were greatly satisfied with those results including no more palmar sweating, less pain, better cosmetics, short hospital stay. In addition, recent use of sweating amount measurement and intraoperative temperature monitoring could make this technique more accurate, so we easily applied thoracoscopic sympathectomy with minimal risk.