• 핵의학기술
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• 제28권1호
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• pp.23-29
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• 2024

Purpose: 99mTc-mebrofenin hepatobiliary scintigraphy (HBS) is an important and clinically useful diagnostic imaging study for detecting complications after liver transplantation. CT contrast agents due to their high atomic numbers, lead to a decrease in gamma ray count rates. This study investigated the impact of CT contrast agents on the uptake of 99mTc-mebrofenin in the liver. Materials and Methods: The quantitative HBS was performed on sixty-two liver transplantation patients (male:female=36:26), with a mean age of 59.4±6.4 years. Statistical comparison of hepatic uptake reduction ratio (HURR%) before and after the injection of CT contrast agents was performed using a paired t-test. Results: Hepatic uptake of the reduction ratio was 94.47±3.65% for the pre-CT contrast agents and 92.17±4.00% for the post-CT contrast agents. HURR% after CT contrast agent injection showed a statistically significant difference compared to before the injection (t=11.09, P<0.001). Conclusion: It will be necessary to pay attention when examining the HBS of patients with liver transplantation after the injection of CT contrast medium. It is advisable to schedule the examination on a different day to prevent residual contrast medium in the body from interfering with the quantitative evaluation of the nuclear medicine examination.

• 한국음향학회지
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• 제29권4호
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• pp.258-264
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• 2010

생활수준의 향상으로 실내용 가전제품 개발의 초점은 제품의 성능 뿐 아니라 소음, 디자인과 같은 요소에 맞추어지고 있다. 청소기는 가전제품 중, 큰 소음을 발생시킴으로써 소음 감소를 위한 많은 연구가 진행되고 있다. 따라서 청소기의 체감 소음 측정 방법에 대한 연구는 청소기 소음 제어에 중요한 역할을 할 것으로 기대된다. 본 논문에서는 청소기 체감 소음 측정을 위하여 청각 시스템을 기반으로 객관적 음질 특징을 제시한다. 인간의 청각 시스템은 특정 주파수 대역에 민감하게 반응하므로, 청각에 민감한 주파수 대역의 소음에너지를 줄이는 것이 중요하다. 본 논문에서는 녹음된 소음의 특정 주파수 영역의 평균 에너지를 계산하여 이를 청소기 음질 측정을 위한 새로운 객관적 특징 값으로 제시한다. 제시하는 객관적 특징 값의 성능을 평가하기 위하여, 14개 청소기의 소음을 녹음한 후, 100명을 대상으로 PCM 및 ACR 주관적 평가 법을 실시하여 주관적 점수를 획득하였다. 제시하는 객관적 특징 값은 주관적 점수와 높은 상관관계를 보여준다.

• Anatomy and Cell Biology
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• 제56권2호
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• pp.252-258
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• 2023

The human fetal sacroiliac joint (SIJ) is characterized by unequal development of the paired bones and delayed cavitation. Thus, during the long in utero period, the bony ilium becomes adjacent to the cartilaginous sacrum. This morphology may be analogous to that of the temporomandibular joint (TMJ). We examined horizontal histological sections of 24 fetuses at 10-30 weeks and compared the timing and sequences of joint cartilage development, cavitation, and ossification of the ilium. We also examined histological sections of the TMJ and humeroradial joint, because these also contain a disk or disk-like structure. In the ilium, endochondral ossification started in the anterior side of the SIJ, extended posteriorly and reached the joint at 12 weeks GA, and then extended over the joint at 15 weeks GA. Likewise, the joint cartilage appeared at the anterior end of the future SIJ at 12 weeks GA, and extended along the bony ilium posteriorly to cover the entire SIJ at 26 weeks GA. The cavitation started at 15 weeks GA. Therefore, joint cartilage development seemed to follow the ossification of the ilium by extending along the SIJ, and cavitation then occurred. This sequence "ossification, followed by joint cartilage formation, and then cavitation" did not occur in the TMJ or humeroradial joint. The TMJ had a periosteum-like membrane that covered the joint surface, but the humeroradial joint did not. After muscle contraction starts, it is likely that the mechanical stress from the bony ilium induces development of joint cartilage.

• 대한통합의학회지
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• 제12권3호
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• pp.143-153
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• 2024

Purpose : Forward head posture (FHP), characterized by the anterior positioning of the head relative to the spine, is a common postural deviation that can lead to neck pain, reduced mobility, and muscle imbalances. Recently, high-frequency deep heat therapy (HFDT) has been gaining attention for the intervention of FHP. This research aims to investigate the efficacy of HFDT in comparison to instrument assisted soft-tissue mobilization (IASTM) for treating FHP among 30 young adults. Methods : Participants were randomly assigned to either the HFDT or IASTM group. The study focused on examining changes in neck joint mobility, pain thresholds, rounded shoulder distance, lower trapezius muscle strength, and neck dysfunction. Measurements were taken before and after the interventions. Paired t-tests were used for within-group analyses, and independent t-tests were employed for between-group comparisons. The statistical significance level α was set to .05. Results : Statistically significant improvements were observed across all measured parameters in both groups (p<.05). The HFDT group showed significantly greater enhancements in neck joint mobility, pain thresholds, rounded shoulder distance, lower trapezius muscle strength, and neck dysfunction parameters. Specifically, HFDT was more effective than IASTM in improving neck joint mobility, right upper trapezius pain threshold, left rounded shoulder distance, and right lower trapezius strength. The only exceptions were neck flexion range of motion, left upper trapezius pain threshold, right rounded shoulder distance, and left lower trapezius strength, where no significant differences were found between the groups. Conclusion : The findings suggest that HFDT, by combining the benefits of high-frequency therapy and manual therapy, effectively alleviates upper trapezius muscle pain and tension, enhances neck mobility, and strengthens lower trapezius muscles. Thus, HFDT could be considered a valuable intervention for clinicians aiming to address FHP and associated musculoskeletal problems.

• 한국전문물리치료학회지
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• 제31권2호
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• pp.151-158
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• 2024

Background: In Taekwondo athletes, ankle sprain is the most common risk factor for injury. Repeated ankle injuries lead to weakness and imbalance of the ankle muscles, resulting in chronic ankle instability (CAI). Both the ankle and toe muscles contribute to the inversion and eversion of the foot at the subtalar joint. Therefore, it is necessary to consider the ankle and toe joint positions when measuring ankle invertor and evertor strength. Objects: This study aimed to compare the muscle strength and ratio differences of the ankle invertor and evertor muscles in both the toe and ankle positions between the CAI and uninjured sides in Taekwondo athletes. Methods: Fifteen Taekwondo athletes participated in this study. The isometric strengths of both the ankle invertor and evertor were determined in different ankle and toe positions (dorsiflexion with toe extension, dorsiflexion with toe flexion, plantarflexion with toe extension, and plantarflexion with toe flexion). Paired t-tests were used to determine the differences between the ankle invertor and evertor in strength and ratio according to toe and ankle positions between the ankle CAI side and the uninjured side. Results: The results demonstrated that ankle evertor strength significantly decreased in all ankle and toe positions on the CAI side (p < 0.05). In addition, significant differences were observed in the ratios of the ankle invertor and evertor strengths in the dorsiflexion with toe flexion, plantarflexion with toe extension, and plantarflexion with toe flexion positions (p < 0.05). Conclusion: The findings of this study suggest that athletes, trainers, and clinicians should consider ankle and toe positions when measuring invertor and evertor strength and develop ankle rehabilitation protocols for Taekwondo athletes with CAI.

• 대한소아치과학회지
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• 제36권1호
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• pp.38-45
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• 2009

본 연구는 상품화된 10% CPP-ACP 크림 (Tooth mousse, GC Co., Japan)이 0.05 % NaF 불소 용액 매일 양치법을 대체할 수 있는지 알아보기 위하여, 인공 탈회 병소를 가진 우치 법랑질에 대해 10일간 위 두 가지 방법 단독 혹은 복합 사용의 재광화 효과를 비교하였다. 0.1% thymol 용액에 냉장 보관한 소의 치아를 교정용 레진 (Orthodotic resin, Dentsply international Inc., USA)에매몰한 후 탈회 용액에 96시간 보관하였고, 총 60개의 시편을 5개의 군으로 나누었다; 비처치군 (1군), 0.05% NaF 용액 1분 (2군), Tooth mousse 3분 (3군), 0.05% NaF 용액 1분 처리 후 Tooth mousse 3분 (4군), Tooth mousse 3분 처리 후 0.05% NaF 용액 1분(5군). 재광화 정도는 10일간의 시편 처리 전 후의 Vickers hardness number를 측정하여 비교하였으며, 연구 결과는 다음과 같다. 1. 각 군에서 시편 처리 전후의 표면경도를 paired t-test를 이용하여 비교분석한 결과, 3, 4, 5 군에서만 유의할만한 표면 경도 증가가 나타났다(P < 0.05). 2. 각 군별로 평균 표면 경도 증가량은 5 > 4 > 3 > 2 > 1 군 순이었고, 각 군의 표면경도 증가량을 one-way ANOVA test로 비교분석한 후 Duncan test로 사후 검정한 결과, 4, 5 군은 1, 2, 3 군과 유의할만한 표면경도 증가를 보였으며 (P < 0.05), 다른 군들 간에는 유의할만한 차이를 보이지 않았다. 3. Tooth mousse를 우치에 10일간 적용시킨 결과 0.05% NaF 용액보다 더 많은 표면경도 변화량을 나타냈지만, 통계학적으로 유의할만한 차이는 없었다. 이상의 결과에서 Tooth mousse 사용은 불소 양치가 용이하지 않은 환자들에게 양호한 대체 방안이 될 것으로 사료되며, 또한 불소 적용시 Tooth mousse를 복합 사용하는 것이 추천될 수 있으리라 사료된다.

• Journal of Oral Medicine and Pain
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• 제33권1호
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• pp.85-95
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• 2008

구강안면통증의 주원인의 하나인 측두하악장애는 다양한 기여요인에 의해 발생하거나 악화되는데, 특히 이갈이, 이악물기 등의 비기능적 구강악습관은 중요한 기여요인으로 고려된다. 구강악습관과 저작근의 관련성에 대해서는 근전도 등을 이용한 연구가 이루어져왔으나, 안면표정근에 미치는 영향에 대해서는 연구된 바가 거의 없다. 그러므로 본 연구는 근육의 탄성도과 경직도를 정량적으로 평가할 수 있는 촉각센서(tactile sensor)를 이용하여 구강악습관이 저작근과 안면표정근에 미치는 영향을 평가하고자 하였다. 건강하고 건전한 치열을 가지고 있으며 Class I 교합관계의 정상골격인 지원자10명(20대 남성)을 연구대상으로 선택하여 촉각센서(Venustron II, Axiom Co, 일본)를 이용하여 이완 상태와 편측 이악물기(피검자가 선호하는 측의 제1대구치 부위에서 교합측정기를 50Kg force의 힘으로 깨문 상태), 턱내밀기(전치 상하절단연이 만나는 위치까지 턱을 내민 상태), 입술힘주기(치아는 닿지 않는 상태에서 입술만 꼭 다문 상태) 상태에서 저작근과 안면표정근의 경직도와 탄성도를 측정하였다. 측정근육은 측두근 전부, 교근(이상 저작근), 전두근, 하안륜근, 대관골근, 상 하 구륜근, 이근(이상 안면표정근)이었다. 통계처리를 위해 paired t-test, correlation coefficients, ANOVA 및 multiple comparison t-tests을 사용하였다. 편측 이악물기를 할 때 측정한 모든 근육에서 경직도와 탄성도는 좌우 차이를 보이지 않고 높은 상관관계를 보였다. 교근은 편측 이악물기 뿐만 아니라 턱내밀기, 입술힘주기의 시행된 모든 구강악습관에 의해 경직도가 증가하고 탄성도는 감소하였다(p<0.05). 측두근과 대관골근은 편측 이악물기의 영향을 받았으며, 상 하구륜근 및 이근의 경직도와 탄성도는 입술힘주기에 의해 크게 변화하였다(p<0.05). 본 연구의 결과는 편측 이악물기, 턱내밀기, 입술힘주기 같은 구강악습관은 저작근뿐만 아니라 안면표정근, 특히 구강주위근육에도 영향을 준다는 것을 보여준다.

• 한국대기환경학회지
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• 제30권4호
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• pp.362-377
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• 2014

Polycyclic aromatic hydrocarbons (PAHs) have been of particular concern since they are present both in the vapor and particulate phases in ambient air. In this study, a simple method was applied to determine the vapor phase PAHs, and the performance of the new method was evaluated with a conventional method. The simple method was based on adsorption sampling and thermal desorption with GC/MS analysis, which is generally applied to the determination of volatile organic compounds (VOCs) in the air. A combination of Carbotrap (300 mg) and Carbotrap-C (100 mg) sorbents was used as the adsorbent. Target compounds included two rings PAHs such as naphthalene, acenaphthylene, and acenaphthene. Among them, naphthalene was listed as one of the main HAPs together with a number of VOCs in petroleum refining industries in the USA. For comparison purposes, a method based on adsorption sampling and solvent extraction with GC/MS analysis was adopted, which is in principle same as the NIOSH 5515 method. The performance of the adsorption sampling and thermal desorption method was evaluated with respect to repeatabilities, detection limits, linearities, and storage stabilities for target compounds. The analytical repeatabilities of standard samples are all within 20%. Lower detection limits was estimated to be less than 0.1 ppbv. In the results from comparison studies between two methods for real air samples. Although the correlation coefficients were more than 0.9, a systematic difference between the two groups was revealed by the paired t-test (${\alpha}$=0.05). Concentrations of two-rings PAHs determined by adsorption and thermal desorption method consistently higher than those by solvent extraction method. The difference was caused by not only the poor sampling efficiencies of XAD-2 for target PAHs and but also sample losses during the solvent extraction and concentration procedure. This implies that the levels of lower molecular PAHs tend to be underestimated when determined by a conventional PAH method utilizing XAD-2 (and/or PUF) sampling and solvent extraction method. The adsorption sampling and thermal desorption with GC analysis is very simple, rapid, and reliable for lower-molecular weight PAHs. In addition, the method can be used for the measurement of VOCs in the air simultaneously. Therefore, we recommend that the determination of naphthalene, the most volatile PAH, will be better when it is measured by a VOC method instead of a conventional PAH method from a viewpoint of accuracy.

• Asian Pacific Journal of Cancer Prevention
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• 제14권4호
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• pp.2243-2248
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• 2013

Background: To compare the dosimetric coverage of target volumes and organs at risk in the radical treatment of nasopharyngeal carcinoma (NPC) between intensity-modulated radiotherapy (IMRT) and three-dimensional conformal radiotherapy (3DCRT). Materials and Methods: Data from 10 consecutive patients treated with IMRT from June-October 2011 in Penang General Hospital were collected retrospectively for analysis. For each patient, dose volume histograms were generated for both the IMRT and 3DCRT plans using a total dose of 70Gy. Comparison of the plans was accomplished by comparing the target volume coverage (5 measures) and sparing of organs at risk (17 organs) for each patient using both IMRT and 3DCRT. The means of each comparison target volume coverage measures and organs at risk measures were obtained and tested for statistical significance using the paired Student t-test. Results: All 5 measures for target volume coverage showed marked dosimetric superiority of IMRT over 3DCRT. V70 and V66.5 for PTV70 showed an absolute improvement of 39.3% and 24.1% respectively. V59.4 and V56.4 for PTV59.4 showed advantages of 18.4% and 16.4%. Moreover, the mean PTV70 dose revealed a 5.1 Gy higher dose with IMRT. Only 4 out of 17 organs at risk showed statistically significant difference in their means which were clinically meaningful between the IMRT and 3DCRT techniques. IMRT was superior in sparing the spinal cord (less 5.8Gy), V30 of right parotid (less 14.3%) and V30 of the left parotid (less 13.1%). The V55 of the left cochlea was lower with 3DCRT (less 44.3%). Conclusions: IMRT is superior to 3DCRT due to its dosimetric advantage in target volume coverage while delivering acceptable doses to organs at risk. A total dose of 70Gy with IMRT should be considered as a standard of care for radical treatment of NPC.

• 한국인터넷방송통신학회논문지
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• 제18권3호
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• pp.1-7
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• 2018

연구의 목적은 3개 모바일 포털사이트의 응답시간을 분포를 이용하여 비교하고 분류하는 것이다. 연구대상은 Naver, Daum, Nate의 모바일 포털 사이트 접속페이지이며, 실험기간은 모바일 포털들이 활성화되기 시작되던 즈음인 2012년 4월 18일에서 2018년 4월 17일까지 6년간이다. 그리고 실험횟수는 4,060회이다. 분포비교를 위해 히스토그램과 백분율을 이용하였으며 이론적인 비교를 위해 모수적 방법인 카이스케어 검정과 비모수적 방법인 콜모고로프-스미르노프 검정을 실시하였다. 네가지 방법 모두 Naver가 가장 빨랐고, 다음이 Nate, Daum이 가장 느렸다. 평균 응답시간 면에서도 같은 결과를 낳았다. 이러한 결과는 유선 포털의 결과와 정반대로서, Naver는 매체 특성에 맞게 유선에서는 많은 콘텐츠를 무선에서는 응답시간을 높이는 전략이고, Daum은 무선에서 응답시간을 희생하면서 콘텐츠를 중시하는 전략을 구사하고 있음을 알 수 있다. 분류에서는 응답시간에 따라 "Comfortable"과 "Tolerable", "Feedback", "Leave"로 나누었으며, 이용자들이 떠날 수 있다는 7초 이상인 "Leave"의 비율이 Naver는 1.18%, Daum이 11.70%, Nate가 1.5%로 Daum이 압도적으로 높아서 Daum의 응답시간은 개선이 매우 절실한 수준임을 알 수 있다. 또한 분류 결과에 의하면 3개 모바일 포털들이 응답시간을 줄이는 것이 필요하다는 것을 밝혔다. 본 논문의 결과가 모바일 포털들의 응답시간을 줄이는 기술경쟁을 촉진할 수 있기를 기대한다.