• Journal of Korean Neurosurgical Society
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• v.47 no.6
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• pp.420-423
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• 2010

Objective : Peripheral nerve injury often leads to neuropathic pain, which is characterized by burning pain, allodynia, and hyperalgesia. The role of the sympathetic nervous system in neuropathic pain is a complex and controversial issue. It is generally accepted that the alpha adrenoreceptor (AR) in sympathetic nerve system plays a significant role in the maintenance of pain. Among alpha adrenoreceptor, alpha-1 receptors play a major role in the sympathetic mediated pain. The primary goal of this study is to test the hypothesis that sympathetically maintained pain involves peripheral alpha-2 receptors in human. Methods : The study was a randomized, prospective, double-blinded, crossover study involving twenty patients. The treatments were : Yohimbine (30 mg mixed in 500 mL normal saline), and Phentolamine (1 mg/kg in 500 mL normal saline) in 500 mL normal saline at 70 mL/hr initially then titrated. The patients underwent infusions on three different appointments, at least one month apart. Thus, all patients received all 2 treatments. Pain measurement was by visual analogue scale, neuropathic pain questionnaire, and McGill pain questionnaire. Results : There were significant decreases in the visual analogue scale, neuropathic score, McGill pain score of yohimnine, and phentolamine. Conclusion : We conclude that alpha-2 adrenoreceptor, along with alpha-2 adrenoreceptor, may be play role in sympathetically maintained pain in human.

• The Journal of Korea CHUNA Manual Medicine
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• v.2 no.1
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• pp.133-142
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• 2001

Objectives : The aim of this study is to investigate the relationship between spinal distortion and pain in elementary and middle school students. Methods : Using the phase-shifting moire developed by KAIST(Korea Advanced Institute of Science and Technology) we measured the back surface distortion, and using questionnaire investigation, we investigated the partial pain in 1008 elementary and middle school students(532 boy students(52.8%), 476 girl students(47.2%)) in Seoul in 1999. And, we statistically analyzed the relationship between spinal distortion and partial body pain Results : This study show that the more age increase, the more the pain in head, neck, shoulder, back and low back Increase considerably among the students aged 9 to 15. The ratio of each partial body pain was 28.4%, 19.7%, 18.2%, 18.7%. 16.0% at the age of 9 and 59.7%, 67.4%, 51.8%, 51.8%, 64.4% at the age of 15 respectively. And, it was shown there was a significant correlation between spine distortion and partial body pain area. When the spinal distortion was found at the upper thoracic and cervical area, the students complained the more pain on head, neck and shoulder(p<0.05) and when the spinal distortion was found at the sacral base, the more headache(p<0.05) Conclusions : It is suggested that the significant correlation exist between the spinal distortion and pain and the pain related to spine disorder get more increase as students grow. We have to study further more about Juvenile postural distortion and it's prevention.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.48 no.5
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• pp.277-283
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• 2022

Objectives: The main purpose of the present study was to investigate the associations between the risk of obstructive sleep apnea (OSA) and chronic orofacial pain in a nationally representative sample of the Korean population. Materials and Methods: Data from the 8th wave Korean national health and nutrition examination survey, which was conducted from 2019 to 2020 were analyzed. This study included 5,780 Koreans (2,503 males, 3,277 females) over 40 years of age. The presence of subjective chronic facial pain lasting more than 3 months was evaluated based on a self-reported questionnaire. The risk of OSA was determined using the STOP-BANG questionnaire. Data related to anthropometric and sociodemographic factors; diagnostic history of hypertension, depression, and OSA; level of health-related quality of life and stress awareness; health-related behaviors, including smoking and alcohol drinking; and sleep duration were collected. The participants were classified into two groups according to the presence of chronic facial pain. Results: The level of health-related quality of life and stress awareness showed significant differences between the two groups. The sleep duration on weekends also presented significant differences. No significant differences were observed in the presence of snoring and observed apnea, while participants with chronic facial pain showed significantly higher levels of tiredness between the groups. The risk of OSA evaluated by STOP-BANG questionnaire showed significant differences between groups; however, the risk of OSA seemed to be higher in participants without chronic facial pain. Conclusion: The participants with chronic facial pain demonstrated decreased sleep duration, lower health-related quality of life, and increased stress and tiredness. Even though, the role of OSA in the development of chronic facial pain was inconclusive from the study, it is possible that ethnicity play a role in relationship between OSA and chronic facial pain.

• Journal of Oral Medicine and Pain
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• v.41 no.2
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• pp.61-71
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• 2016

Purpose: This study was designed to evaluate the comparison between the subjective and the objective evaluation of pain control effect in masticatory muscle pain depending on time and dose change. Methods: The patients were recruited to this study and diagnosed according to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD). Experimental group were divided into three groups; saline injection group (n=10), morphine 1.5 mg injection group (n=10), and morphine 3.0 mg injection group (n=10). Evaluation list was the subjective pain evaluation (visual analogue scale, McGill pain questionnaire) and the objective pain evaluation (pressure pain threshold [PPT], pressure pain tolerance [PTO]). The subjective and the objective pain evaluation were performed at the times of just before injection, 10 minutes, 30 minutes, 1 hour, 24 hours, and 48 hours after injection. Then, data were statistically analyzed. Results: The results were as follows: 1) There is no statistically significant difference between the results of the subjective and the objective pain evaluation with regard to the short-term (within 1 hour) analgesic effect of morphine sulfate. 2) However, after 1 hour of injection, while the subjective pain evaluation score still decreased, the objective pain evaluation didn't show significant changes in PPT and PTO (1 hour, p<0.05; 24 hours, p<0.01; 48 hours, p<0.001). 3) In comparison to changes in the dose, the McGill pain questionnaire was the most statistically effective method among the subjective pain evaluations (1.5 mg, p<0.05; 3 mg, p<0.01). Conclusions: Therefore, it was revealed that the subjective pain evaluation was more effective to evaluate long-term pain control, and that the McGill pain questionnaire could be an effective way to evaluate pain control depending on dose changes. It requires further investigations with time and dose extension.

• Korean Journal of Acupuncture
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• v.24 no.2
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• pp.99-112
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• 2007

Objectives : It was to translate three neck and spinal pain disability questionnaires - the Neck Disability Index (NDI), the Neck Pain and Disability Scale (NPDS), and the Functional Rating Index (FRI) - into Korean language, and evaluate the psychometric properties of Korean versions of questionnaires to achieve a good cross-cultural adaptation. Methods : Forty (23 males, 17 females) subjects aged from 15 to 64 years old, participated to examine test-retest reliability. One hundred and eighty (76 males, 104 females) subjects with a primary diagnosis of non-specific neck pain and 81 healthy volunteers were undertaken to examine internal consistemcy, discriminative validity and longitudinal construct validity. Versions of each questionnaire in idiomatic modern Korean were developed using a procedure proposed by Beaton et al. (2000). To assess reliability, the Intraclass Correlation Coefficient (ICC $_{(2,1)}$) was calculated. Internal consistency was evaluated by Cronbach's alpha. Discriminative validity was examined with independent-group t-tests. Responsiveness was tested by calculating the effect size and standardized response mean for each questionnaire and using Pearson' s r and the area under the receiver operating characteristic curve analysis. Results : Test-retest reliability ofthe translated versions of the three disability questionnaires was excellent (ICC $_{(2,1)$ = 0.86-0.90). High internal consistency was found in the three disability questionnaires (Cronbach's alpha ranged from ${\alpha}=0.88$ for the FRI to ${\alpha}=0.96$ for the NPDS and 0.82 for the Short Form McGill Pain Questionnaire(SFMPQ)). the VAS subscale of the SFMPQ was found to be the most responsive of the subscales (ES=1.44, SRM=1.37). The VAS was also the most responsive pain and disability index in internal responsiveness analysis, although disability indices showed marginally better responsiveness when compared with external standards. No floor or ceiling effects were observed. Conclusions : It is concluded that the questionnaires were successfully translated and exhibit acceptable measurement properties, and may suggest that they are suitable for use in clinical and research application.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.14 no.1
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• pp.111-118
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• 2010

Objective : The study was performed to evaluate the effect of Kinesio taping on pain of Left hip joint. Methods : A 35-year-old, female patient who suffers from pain of left hip joint by brain tumor was treated by Kinesio taping therapy. The improvement of the patient's pain of left hip joint was evaluated by Visual Analog Scale(VAS), Faces Pain Rating Scale, McGill Pain Questionnaire(MPQ), and Pain Rating Score(PRS). Result : During the 9 days with Kinesio taping, VAS and Pain Rating Scale were decreased slightly. But Faces Pain Rating Scale and McGill Pain Questionnaire showed no change. Conclusions : The result suggests that Kinesio Taping was effective treatment to pain but not intensive. Further study is needed to evaluate the significancy of this report.

• The Korean Journal of Pain
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• v.11 no.2
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• pp.273-282
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• 1998

Background: Twelve years have passed since the Korean Pain Society was organized. Nowadays, there are so many problems to be solved in pain clinics including health insurance, pain education and public information etc. in Korea. The present study was designed to evaluate the current status of pain clinics in Korea. Methods: Eight hundred twenty regular members of Korean Pain Society were surveyed by questionnaire in October 1997. We compared the general characteristics, contents of diseases in pain clinic, treatment Methods, patients satisfaction, pain educations, problems in pain treatments, requests to Korean Pain Society among the 138 respondents. Results: Thirty seven percents of the respondents worked at university hospitals, 39% at non-university hospitals and 24% at private pain clinics. The most common diseases treated in pain clinics was low back pain(32% in university and non-university hospital and 28% in private pain clinic respectively). However, cancer pain was 10% in university and non-university hospital and 0.7% in private pain clinic. Epidural block was the most frequently used procedure in chronic pain treatments. And 74.6% of the respondents were studied and learned in Korea and Japan. And then, current problems in pain management and requests to Korean Pain Society were medical insurance problems, pain education and public information of pain clinics. Conclusions: These results suggest that the Korean Pain Society should make an effort to solve these current problems in order to activate pain medicine and increase the quality of life for those suffering from pain.

• Physical Therapy Korea
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• v.16 no.2
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• pp.24-30
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• 2009

The purpose of this study was to determine the reliability and validity of the fear-avoidance beliefs questionnaire (FABQ) in assessing Korean patients with low back pain. We performed translation and cross-cultural adaptation of the questionnaire and enrolled 52 patients (18 males and 34 females) with low back pain. The subjects completed a standardized self-administered questionnaire that included the FABQ assessment along with evaluations for the visual analogue scale (VAS), Oswestry disability index (ODI), self-rating anxiety scale (SAS), and Beck depression inventory-Korean version (K-BDI). The reliability of the obtained data was determined by evaluating the internal consistency on the basis of the intraclass correlation coefficient (ICC) and the Cronbach's alpha values, while the validity of the data was examined by correlating the FABQ scores to the VAS, ODI, SAS, and K-BDI scores. The translated versions of the FABQ showed good test-retest reliability: ICC (3, 1)=.90 (FABQ for physical activity) and .97 (FABQ for work) these values were statistically significant (p<.01). The Cronbach's alpha value for FABQ was .90 (p<.01). FABQ moderately correlated with pain, disability, anxiety, and depression (p<.01). The results of this study indicate that the Korean version of the FABQ is a reliable and valid instrument for measuring fear-avoidance beliefs in Korean patients with low back pain.

• Journal of Korean Physical Therapy Science
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• v.22 no.1
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• pp.29-36
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• 2015

Purpose : The purpose of present study was to improve communication of pain expressing terms and pain intensity between patient and physical therapist, and initiated to objectify a measurement of subjective pain. Methods : Data were delivered to 249 people by a self-completion questionnaire, and analyzed 160 copies except for 87 mark error of the collected 247 questionnaires. The questionnaire included a question on 55 terms used to describe pain, the type of the pain, and pain intensity using VAS (visual analogue scale). Results : The results were as follows; 'Tight' was the most frequently being expressed term of muscular pain, subsequently to 'knot' and 'dull'. 'Tear' was the term representing the most strong pain of muscular pain, subsequently to 'rupture' and 'squeeze'. 'Stinging' was the most frequently being expressed term of neurologic pain, subsequently to 'get shocked' and 'wriggle'. 'Burn' was the term representing the most strong pain of neurologic pain, subsequently to 'sear' and 'get shocked'. 'Creak' was the most frequently being expressed term of joint pain, subsequently to 'peel' and 'out of joint'. 'Break' was the term representing the most strong pain of joint pain, subsequently to 'peel' and 'crack'. Conclusion : The objectification of pain terms will be used to help physical therapist to check the patient's pain.

• The Korean Journal of Pain
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• v.35 no.2
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• pp.209-223
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• 2022

Background: The coronavirus disease 2019 (COVID-19) pandemic has caused significant changes. This study aimed to investigate the impact of COVID-19 on patients with chronic pain. Methods: Patients with chronic pain from 23 university hospitals in South Korea participated in this study. The anonymous survey questionnaire consisted of 25 questions regarding the following: demographic data, diagnosis, hospital visit frequency, exercise duration, time outside, sleep duration, weight change, nervousness and anxiety, depression, interest or pleasure, fatigue, daily life difficulties, and self-harm thoughts. Depression severity was evaluated using the Patient Health Questionnaire-9 (PHQ-9). Logistic regression analysis was used to investigate the relationship between increased pain and patient factors. Results: A total of 914 patients completed the survey, 35.9% of whom had decreased their number of visits to the hospital, mostly due to COVID-19. The pain level of 200 patients has worsened since the COVID-19 outbreak, which was more prominent in complex regional pain syndrome (CRPS). Noticeable post-COVID-19 changes such as exercise duration, time spent outside, sleep patterns, mood, and weight affected patients with chronic pain. Depression severity was more significant in patients with CRPS. The total PHQ-9 average score of patients with CRPS was 15.5, corresponding to major depressive orders. The patients' decreased exercise duration, decreased sleep duration, and increased depression were significantly associated with increased pain. Conclusions: COVID-19 has caused several changes in patients with chronic pain. During the pandemic, decreased exercise and sleep duration and increased depression were associated with patients' increasing pain.