• The Korean Journal of Physiology and Pharmacology
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• 제10권6호
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• pp.297-302
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• 2006

Melittin, a major component of bee venom, produces a sustained decrease in mechanical threshold, and an increase in spontaneous flinchings and paw thickness, which are characteristics similar to those induced by whole bee venom. Melittin-induced nociception has been known to be modulated by the changes in the activity of excitatory amino acid receptors, voltage-dependent calcium channels, cyclooxygenase and serotonin receptors. The present study was undertaken to investigate the role of calcium chelators (TMB-8 & Quin 2) in melittin-induced nociceptive responses. Changes of mechanical threshold and spontaneous flinching behaviors were measured at a given time point following intraplantar injection of melittin ($30{\mu}g/paw$). Intrathecal or intraplantar pre-administration and intrathecal posttreatment of TMB-8 and Quin 2 significantly prevented the melittin-induced reduction of mechanical threshold, and intraplantar or intrathecal pre-treatment of TMB-8 and Quin 2 suppressed melittininduced flinching behaviors. These results indicate that calcium ion in the spinal dorsal horn neurons and peripheral nerves plays an important role in the production and maintenance of mechanical allodynia and spontaneous pain by melittin.

• 한국학교ㆍ지역보건교육학회지
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• 제20권2호
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• pp.93-107
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• 2019

Objectives: The purpose of this study is to provide basic data on the developement of oral health programs to maintain correct oral health in adolescence by identifying the relevance of health-related behavior and symptom experience to adolescents. Methods: Using the 14th(2018) online survey of youth health behavior, this study was conducted on students in grades1 middle school to grade5 high school in Korea and 30,463 boys, 29,577 girls were selected as the final analysis targets. Results: During the oral disease symptom experience, there was a statistically significant difference in smoking experience with teeth pain controlled general characteristics during eating. Conclusions: It is expected that it will be used as basic dat for the development of oral health programs to maintain the correct oral health status of adolescents by identifying the effects of health-related behaviors and related variables on oral diseases in Korea.

• 대한간호학회지
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• 제51권3호
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• pp.347-362
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• 2021

Purpose: This study developed a cognitive behavioral therapy program aimed at altering the physical condition, emotions, and behaviors of fibromyalgia patients, and confirmed the program's clinical applicability. The program was developed by analyzing previous studies conducting in-depth interviews with fibromyalgia patients, drawing on cognitive behavior theory to establish the program contents, recruiting experts to test its validity, and conducting a preliminary survey. Methods: To confirm the program's effect, this study used a randomized controlled trial design. The participants were outpatients diagnosed with fibromyalgia in Dong-A University Hospital, Busan. The 30 patients in the experimental group took part in the program, which comprised 8 sessions (90 to 120 minutes) based on cognitive behavior theory, delivered over 8 weeks. Hypothesis testing was carried out using the repeated measures ANOVA. Results: The analysis revealed significant differences between the experimental and control groups in positive automatic thoughts, pain, fatigue, depression, and interpersonal relationships. However, there was no significant difference between the groups in terms of sleep disorders and negative automatic thoughts. Conclusion: This program is a positive effect on physical condition, emotions, and behaviors. It is thus expected to be used to help fibromyalgia patients improve their disease conditions.

• 한국치위생학회지
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• 제21권4호
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• pp.349-356
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• 2021

연구목적: 본 연구는 다문화가정 청소년의 정신건강과 구강자각증상과의 관련성을 알아보고자 한다. 연구방법: 청소년건강행태 온라인 조사의 자료를 바탕으로 정신건강은 스트레스, 우울, 자살생각을 조사하였고, 구강자각증상은 외상, 통증, 잇몸출혈을 조사하였다. 일반적 특성에 따른 정신건강, 구강자각증상은 복합표본 교차분석을 시행하였고, 정신 건강과 구강자각증상의 관련성은 복합표본 로지스틱회귀분석을 시행하였다. 연구결과: 스트레스와 우울은 통증과 잇몸출혈이 관련성이 있었고, 자살생각은 외상과 관련이 있었다. 결론: 본 연구결과, 다문화가정 청소년의 정신건강에 따른 구강건강을 위한 구강보건계획 및 방안이 마련되어야 할 것이다.

• 치위생과학회지
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• 제15권4호
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• pp.480-487
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• 2015

본 연구는 2013년 KNHANE 자료를 이용하여 우리나라 성인의 구강건강 상태와 HRQoL 관련성을 EQ5D 구성요소를 중심으로 평가하고자 하였다. 16~64세 성인 3,252명을 최종 분석대상자로 하여 다음과 같은 결론을 얻을 수 있었다. 치아통증과 운동능력, 통증 및 불편은 통계적으로 유의한 관련성을 나타냈고, 저작 불편과 말하기 불편은 EQ5D 구성요소 5가지 모두 통계적으로 유의한 관련성을 나타냈다. 주관적 구강건강 인식은 자기관리, 일상활동, 통증 및 불편, 불안 및 우울과 통계적으로 유의한 관련성을 나타내어 구강건강 상태와 EQ5D 구성요소의 관련성을 확인하였다. 또한 EQ5D 구성요소에 미치는 영향을 통제변수를 보정 후 로지스틱 회귀분석으로 살펴본 결과 치아통증, 저작 불편, 말하기 불편, 주관적 구강건강 인식이 불안 및 우울에 영향을 미치는 것으로 나타났다. 구강건강 증진은 HRQoL을 향상시킬 수 있는 방안이 되므로, 구강건강의 중요성을 인식하고 예방차원의 교육 및 프로그램이 필요하다고 생각된다.

• 한국콘텐츠학회논문지
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• 제14권8호
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• pp.297-306
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• 2014

본 연구는 초등학생의 긍정적인 월경태도 형성을 위한 프로그램 개발의 기초연구로서, 초등학생의 월경에 대한 태도, 증상 및 대처방법을 파악하기 위해 시도된 서술적 조사연구이다. 초경의 평균연령은 12.3세였고, 월경에 대한 태도는 전체적으로 부정적인 태도를 보였으며 초경 경험군 2.93점으로, 비경험군 2.86점에 비해 상대적으로 긍정적인 태도를 보였으나 유의미한 차이는 없었다. 초경 경험군에서의 월경증상은 2.12점으로 중간점수인 3점보다 낮은 점수를 보여 월경 증상이 거의 없거나 보통으로 느끼고 있는 것으로 나타났으며, 월경증상의 하부요인 중 '통증'을 가장 많이 호소하였다. 또한 월경 시 대처방법으로 '따뜻한 물로 샤워한다', '휴식을 취하거나 잠을 잔다'를 가장 많이 선택하였으며, '비타민 B를 섭취한다', '진통제를 복용한다' 등의 약물복용 항목은 거의 선택하지 않았다. 본 연구의 결과를 토대로 하여 초등학생의 월경태도에 영향을 미치는 요인에 대한 깊이 있는 체계적인 후속연구와 월경에 대한 긍정적인 태도를 갖게 하기 위한 효과적인 월경에 대한 보건교육과 월경에 대한 증상과 대처방법을 선택하기 위한 교육 및 상담 등을 제언하고자 한다.

• 근관절건강학회지
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• 제24권3호
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• pp.159-170
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• 2017

Purpose: The purposes of this study were to identify musculoskeletal symptoms and to investigate factors associated with musculoskeletal symptoms in small and medium sized hospital nurses. Methods: The data were collected from 206 nurses working in Jeonnam. We used self administration questionnaires of KOSHA GUIDE H-9-2012 for musculoskeletal symptoms, PWI-SF for psychosocial stress, KOSS for job stress, and HPLP-II for health behaviors. The collected data were analyzed using the $x^2$, t-test, and logistic regression analysis in SPSS Ver. 23.0. Results: Sixty-six percent of the subjects had musculoskeletal symptoms. The shoulder had the highest symptom at 38.3%, followed by lower back at 32.5%, and neck at 29.1%. The mean and standard deviation score of psychosocial stress were $24.06{\pm}6.01$, those of job stress were $2.38{\pm}0.23$, and those of health behaviors were $2.14{\pm}0.39$. The items that were significantly different according to musculoskeletal symptoms were career ($x^2=6.67$, p<.036), one week overtime ($x^2=7.27$, p<.026), subjective health status ($x^2=4.29$, p<.038), and psychosocial stress ($x^2=7.99$, p<.010). In logistic regression analysis, career, and psychosocial stress were found to affect musculoskeltal symptoms. Conclusion: It is necessary to conduct preventive intervention to reduce musculoskeletal symptoms according to career and psychosocial stress for small and medium sized hospital nurses.

• Clinical and Experimental Pediatrics
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• 제48권4호
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• pp.433-437
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• 2005

위석은 비교적 흔하지 않은 질환이지만, 진단을 못할 경우 위궤양과 출혈, 장천공, 장중첩증, 장폐쇄, 복막염 등의 심각한 합병증을 동반할 수 있는 만성적 복통의 한 원인이며, 모발석 환아의 대부분은 발모벽과 식모증의 과거력이 있다. 저자들은 내원 4년 전까지 자기 머리카락을 뽑아서 먹는 습관이 있었고, 이후 간헐적 복통과 오심, 구토를 일으킨 11세 여아에서 모발석을 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• 한국치위생학회지
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• 제10권4호
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• pp.585-593
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• 2010

Objectives : The purpose of this study were to measure the effect of factors analyse the associated by the dental treatment fear of level middle school student's, and then to provide basic material which can help to improve adolescent's oral health and dental service. Methods : This subject of study consists of 342 middle schools each 1,2,3 grade Daegu city. The data were collected from July through August 2009, by way of the self-reported questionnaire. The data materials are analyzed by general characteristics and dental service behavior frequency analysis, dental fear of levels general characteristics, dental service behavior, the burden of dental visits, the pain experience of the past ${\chi}^2$-test and dental treatment fear relationship with multiple regression analysis. Results : General characteristics, 56.7% for boys and girls, with 43.3 percent of boys and girls high. dental service behavior in the dental visited was treatment purpose 76.5%, preventive purpose 23.5%. high-level dental treatment fear of the female 60.8%, male 33.0% was higher, The higher age also increased dental fear of the levels, dental services dental visit in 1-2 year the dental fear level of the higher, was statistically significant (p<0.05). Medical purpose 'preventive' than 'treatment' is a higher dental fear. Factors affecting dental treatment fear experiences directly from your pain (${\beta}$=0.116), inadequate anesthesia, treatment experience (${\beta}$=0.126), indirect painful experience (${\beta}$=0.125) in both a statistically significant positive relationship was found (p<0.05). Conclusions : Finally, it is necessary carry out further studies on the improvement of dental service of oral health of adolescent based on the dental treatment fear.

• Korean Journal of Acupuncture
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• 제30권1호
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• pp.47-55
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• 2013

Objectives : The purpose of this study was to determine whether electroacupuncture(EA) is effective in reducing pain on the severe ankle sprain classified as grade 3 in rats. Methods : The severe(grade 3) ankle sprain model was induced surgically by ankle ligament injury(the anterior talofibular, the calcaneofibular and the posterior talofibular) in the Sprague-Dawley rats(180~250 g). The effects of EA on weight bearing forces(WBR) of the affected foot were examined in a rat model of ankle sprain. EA was applied to either SI6, ST37, GB34, GB39 or GB42 acupoints by trains of electrical pulses(2 Hz, 1 ms pulse width, 2 mA intensity) for 15 min. Results : Cutting of the lateral ankle ligament complex produced the severe ankle sprain symptoms as grade 3. EA of the contralateral SI6 resulted in more analgesic effect than one of ipsilateral SI6 even though there was significant effect. EA of the ipsilateral GB34 and GB39 produced potent analgesic effects on the surgical ankle sprained pain behaviors. However, there were no significant analgesic effects in the contralateral GB34 and GB39 EA groups. In addition, both side of ST37 and GB42 did not result in analgesic effect on the surgical ankle sprained rat. Conclusions : The data suggest that EA induced analgesia shows point specificity on the severe ankle sprained pain model classified as grade 3.