• Journal of Life Science
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• v.8 no.4
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• pp.366-366
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• 1998

To investigate the effect of Ssanghwatang and Ssanghwatang-mixed-Paedoksan on the recovery of exercise induced fatigue, we observed content changes of lactate, LDH, glucose, FFA as metabolic substance in the serum of rats administered these drugs just after adn 120 minutes after maximum swimming,. The results were obtained as follows: 1. Lactate was found to be decreased in the rats with administration of Ssanghwatang and Ssanghwatang-Mixed-Paedoksan, 2. serum LDH activity was found to be decreased in the rats with administration of Ssanghwatang-Mixed-Paedoksan, 3. glucose was found to be increased in the rats with adiministation of Ssanghwatang-Mixed-Paedoksan, 4. FFA was found to be decreased in the rats with administation of Ssanghwatang and Ssanghwatang-Mixed-Paedoksan,.

• Journal of Life Science
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• v.8 no.4
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• pp.336-372
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• 1998

To investigate the effect of Ssanghwatang and Ssanghwatang-mixed-Paedoksan on the recovery of exercise induced fatigue, we observed content changes of lactate, LDH, glucose, FFA as metabolic substance in the serum of rats administered these drugs just after adn 120 minutes after maximum swimming,. The results were obtained as follows: 1. Lactate was found to be decreased in the rats with administration of Ssanghwatang and Ssanghwatang-Mixed-Paedoksan, 2. serum LDH activity was found to be decreased in the rats with administration of Ssanghwatang-Mixed-Paedoksan, 3. glucose was found to be increased in the rats with adiministation of Ssanghwatang-Mixed-Paedoksan, 4. FFA was found to be decreased in the rats with administation of Ssanghwatang and Ssanghwatang-Mixed-Paedoksan,.

• Korean Journal of Pharmacognosy
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• v.48 no.3
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• pp.213-218
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• 2017

In order to search for anticancer agent as therapy of oral squamous cell carcinoma (OSCC) and malignant pleural mesothelioma (MPM) from Korean traditional prescriptions, we selected 58 traditional prescriptions based on a review of the Korean traditional medicine books. Among the selected traditional prescriptions, only water extracts of paedoksan (敗毒散) showed relatively good cytotoxicity at the concentration of $50{\mu}g/ml$. Additionally, we evaluated cytotoxicity for various paedoksans and each herbal ingredient in paedoksans. The root of Anthriscus sylvestris exhibited more cytotoxic effect than any other ingredients in paedoksans. Bioactivity-guided fractionation of the MC layer of Anthriscus sylvestris led to the isolation of deoxypodophyllotoxin (DPT). DPT exhibited dose-dependently significant cytotoxicity against OSCC and MPM cell with nM range. Therefore, DPT from A. sylvestris might be a potential candidate as an effective anticancer therapeutic agent for OSCC and MPM.

• The Journal of Pediatrics of Korean Medicine
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• v.18 no.1
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• pp.105-129
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• 2004

Methods: It was studied on the 47 kinds of oriental medical literature for fecal blood. Results: Fecal blood means bleeding with faces from anus and indicates all the three cases such as blooding before and after evacuation, evacuation of feces mixed with blood, and simple melena. The main causes are fire(火) and deficiency of spleen qi (脾氣虛). According to the color of fecal blood and the region of the bleeding, first, if the blood color is dark-red and blood discharges after emptying the bowels, it is called deposited poison into Jang(臟毒) or distant bleeding(遠血), and if the color of blood is clear and bowel emptying occurs after bleeding, it is bloody stool due to intestinal wind(腸風) or nearby bleeding(近血). For treating methods(治法). removing heat from the blood and stopping bleeding(淸熱凉血止血), removing dampness and stopping bleeding(淸熱除濕止血), invigorating Ki for promoting Hul-controJ(益氣攝血), warming the spleen and stomach to dispel cold and stopping bleeding(溫中散寒止血) etc are applied. As for the treating prescriptionl(治法), a Hwangtotang(黃土湯). Jeoksodudanggwitang(赤小豆當歸散). Gwihwasan(槐花散). Wipungtang(胃風湯). Hwangnyeonhwan modifying(黃連丸加減). Samultang modifying(四物湯加減). Paedoksan modifying(敗毒散加減) etc are used. As for acupuncture and moxibustion(鍼灸療法). if etiology(病因) is damp-heat(濕熱), acupuncture(刺鍼) at Janggang(長强); Charyo(BL 32); Sangeoheo(ST 37)(上巨虛); Seungsan(BL 57)(承山穴), and in case of deficiency of spleen Gi(脾氣虛), acupunture(刺鍼) with tonification(補法) at I Baek(EX-UE 2)(二白); Gwanwon(CC 4)(關元); Joksamni(ST 36)(足三里) Taebaek(SP 3)(太白); Hoeeum(CC 1)(會陰穴), or mxibuston(灸) at Baekoe(GC 2O)(百會); Myeongmun9GC (命門) or the point of opposite to umbilicus among spinal vertebrae(脊中對臍穴) are used. The external treatment(外治療法) was consisted of plastering umbilicus therapy(敷臍法) and enema therapy(灌腸法).