• Title/Summary/Keyword: Pacific Park

Search Result 1,189, Processing Time 0.026 seconds

The inhibitory Effect of Sanggenon C from the Root-bark of Morus alba L. on the Growth and the Cellular Adherence of Streptococcus mutans (상백피의 Sanggenon C에 의한 Streptococcus mutans의 생육 및 균부착 저해효과)

  • Park, Won-Jae;Lee, Hyung-Jae;Yang, Seung-Gak
    • YAKHAK HOEJI
    • /
    • v.34 no.6
    • /
    • pp.434-438
    • /
    • 1990
  • The methanolic extract of the root-bark of Morus alba L.(Mulberry tree) has the potent antibacterial activity against Streptococcus mutans. Its active component was identified to be sanggenon C. The active component had stronger anti-bacterial activity than berberine, having minimum inhibitory concentration(MIC) of $25\;{\mu}g/ml$. Moreover, the inhibitory effect of this component on the cellular adherence of Streptococcus mutans to glass surfaces also was more remarkable than that of berberine in the presence of glucosyltransferase(GTase) and sucrose in vitro. These results indicate that sanggenon C may play an important role in inhibiting plaque formation and caries incidence.

  • PDF

Phase behaviors, lamellar structures, and physical properties of synthetic vitamin E ceramide (Tocomide) mixed with cholesterol and linoleic acid

  • Lee, Young-Jin;Kim, Do-Hoon;Park, Ho-Sik;Kang, Hyung-Seok;Kim, Joong-Soo;Kim, Han-Kon
    • Proceedings of the SCSK Conference
    • /
    • 2003.09b
    • /
    • pp.357-368
    • /
    • 2003
  • II-A isotherms and phase behaviors of 'tocomide', a newly synthesized 1,3-bis(N-(2-hydroxyethyl)-tocopherol succinylamino)-2-hydroxypropane, mixed with cholesterol and linoleic acid, was studied for its monolayer miscibility and a stable delivery formulation for antioxidant applications. The monolayer of tocomide and cholesterol was formed in a homogeneously mixed state at air-water interface. The ternary mixtures with linoleic acid showed various bulk structures, including a stable and transparent solution of thermodynamically stable lamellar phase. The lamellar structure was confirmed by the X-ray diffraction (XRD) patterns and polarized microscopy such that pure tocomide formed a liquid crystal at room temperature with a lamellar periodicity of 36.7 $\AA$(2$\theta$=2.41$^{\circ}$).

  • PDF

Design, Synthesis and Biological Activities of Novel Vanilloid Receptor Antagonists

  • Lee, Bo-Young;Suh, Young-Ger;Lee, Yong-Sil;Min, Kyung-Hoon;Kim, Jin-Kwan;Seung, Ho-Sun;Park, Young-Ho
    • Proceedings of the PSK Conference
    • /
    • 2003.04a
    • /
    • pp.244.1-244.1
    • /
    • 2003
  • Advances in understanding of pain and analgesia have been made. Over the past few years, we have designed and synthesized a series of VR agonists, based on the structures of 12-HPETE and capsaicin. the natural VR agonist. But for the development of analgesic drugs, these synthetic VR agonists had problems like burning sensation. hypothermia. etc. So our recent studoes have focused on designs and syntheses of VR antagonists based on the structure of capsaicin(natural VR agonist), and capsazepine(synthetic VR antagonist). (omitted)

  • PDF

Stable expression of N-terminal 3X-FLAG tagged human 5a-reductase type II in 293 cells: a new tool for protein purification & inhibitor screening

  • Lee, Chang-Hoon;Park, Won-Seok;An, Su-Mi;Nam, Gae-Won;Kim, Kwang-Mi;Kim, Seung-Hoon;Lee, Byeong-Gon;Jang, Ih-Seop
    • Proceedings of the PSK Conference
    • /
    • 2002.10a
    • /
    • pp.324.1-324.1
    • /
    • 2002
  • Human 5-reductase type II(5AR2) is an important target for the treatment of benign prostatic hyperplasia. In this study we describe the establishment of cell line which stably expressed 3X FLAG tagged human 5AR2. We used this cell line as a cell based assay tool and source for 5AR2 enzyme. First a plasmid (3XFLAGpCMVl0-5AR2) for the expression of 5AR2 was constructed by the use of the vector 3XFLAGpCMV10 and transfected into the HEK 293. By selection with G418 sulfate. ten HEK 293 single cell clones were obtained of which three stably exhibited high 5AR2 activity. (omitted)

  • PDF

Physico-chemial Properties of Pacific Whiting Surimi by Acid-Aided Processing

  • Park, Y.J.;Kim, B.J.;Lee, K.W.;Y.J. Cho;Park, J.W.
    • Proceedings of the Korean Society of Fisheries Technology Conference
    • /
    • 2000.10a
    • /
    • pp.79-80
    • /
    • 2000
  • Conventional surimi processing from white flesh fish, such as Pacific whiting and Alaska Pollee utilizes only <25% of the body (Toyoda and others 1992; Park and others 1997). Conventional surimi is refined myofibrillar proteins processed by removing unnecessary foreign materials such as fat, pigment skin, and water soluble sarcoplasmic proteins. The acid-aided process demonstrated excellent gel forming ability for cod and mackerel with extremely higher yield (Hultin and Kelleher 1999). (omitted)

  • PDF

Feeding Habits of the Pacific Cod Gadus macrocephalus in Southeast Sea of Korea (한국 남동부해역 대구 Gadus macrocephalus의 식성)

  • Lee, Jeong-Hoon;Kim, Jung Nyun;Park, Junsu;Park, Tamina;Nam, Ki Mun
    • Korean Journal of Ichthyology
    • /
    • v.27 no.2
    • /
    • pp.142-148
    • /
    • 2015
  • The feeding habits of the Pacific cod Gadus macrocephalus were studied using 620 specimens collected by bottom trawl and pound net in the Southeast sea of Korea, from February 2012 to June 2013. Of 620 specimens, 192 contained food and 428 were empty. The total length (TL) of individuals used in this study ranged from 20.4 to 95.2 cm. Pacific cod mainly consumed Pisces, Macrura, and Cephalopoda. Its diet also included small quantities of Anomura, Brachyura, Mysidacea, Isopoda and Amphipoda. The proportion of Pisces in prey items increased with increasing Pacific cod length, but seasonal difference was not observed. The proportion of Macrura and Cephalopoda decreased with growth, and seasonal differences were apparent. Macrura were taken there mainly from autumn to winter, whereas Cephalopoda were consumed from spring to summer.

Comparison of Stomach Contents of Pacific Cod (Gadus macrocephalus) in Korean Coastal Waters (우리나라 연안에 서식하는 대구(Gadus macrocephalus)의 위 내용물 비교)

  • Park, Chung Youl;Gwak, Woo Seok
    • Korean Journal of Ichthyology
    • /
    • v.21 no.1
    • /
    • pp.28-37
    • /
    • 2009
  • The diet of Pacific cod (Gadus macrocephalus) in the East Sea, Yellow Sea and Jinhae Bay was studied by analysis of stomach contents. In total, 518 individuals ranging from 15.5 to 77.0 cm standard length SL were analyzed. Prey organisms of the Pacific cod in the East Sea consistedof Caridea, Cephalopoda and Pisces, whereas In the Yellow Sea, the main food items of Pacific cod were similar to those of East Sea Pacific cod except for Cephalopoda. Interestingly, the stomach contents of Pacific cod in Jinhae Bay is mainly Pisces, which is in contrast to those of the two different coastal areas, the East Sea and the Yellow Sea. Although various species of food were eaten by smaller Pacific cod, both Caridea and Pisces were mainly taken by larger Pacific cod. Consequently, the diet of Pacific cod within acertain size is mainly influenced by prey abundance and prey-size spectrum in its habitat. Higher stomach emptiness of Pacific cod in Jinhae Bay might indicate that fully matured Pacific cod temporally stop feeding during their spawning period.

Estimation of Genetic Parameters and Breeding Value for Measurement Traits of Pacific Oyster Crassostrea gigas at Nine Months Old (9개월령 참굴의 계측형질에 대한 유전모수 및 육종가 추정)

  • Park, Ki-Yeol;Kim, Hyun-Chul;Kim, Byoung-Hak;Choi, Nack-Joong;Moon, Tae-Seok
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.42 no.6
    • /
    • pp.600-603
    • /
    • 2009
  • Genetic and phenotypic parameter estimates for measurement traits were obtained from pacific oyster Crassostrea gigas at nine months old. For the growth-related traits among nine months old pacific oyster, heritabilities of shell length, shell height, shell width, total weight, body weight and shell weight were estimated as 0.4855, 0.5248, 0.0884, 0.7236, 0.7726 and 0.6957, respectively. Genetic correlations among the growth-related traits of pacific oyster at nines month old, shell length, shell height, shell width, total weight, body weight, shell weight were showing highly positive correlations. Breeding value on growth-related traits of pacific oyster at nine months old were estimated as shell length -7.044-11.870, shell height -11.380-18.370, shell width -1.234-2.831, total weight -8.339-17.140, body weight -1.813-3.507 and shell weight -4.422-8.837. The results show that there is quite substantial additive genetic variance for measurement traits in pacific oyster that can be exploited through selective breeding.