• Title/Summary/Keyword: PU.1

Search Result 688, Processing Time 0.028 seconds

Evaluation of Galactomannan Enzyme Immunoassay and Quantitative Real-Time PCR for the Diagnosis of Invasive Pulmonary Aspergillosis in a Rat Model

  • Lin, Jian-Cong;Xing, Yan-Li;Xu, Wen-Ming;Li, Ming;Bo, Pang;Niu, Yuan-Yuan;Zhang, Chang-Ran
    • Journal of Microbiology and Biotechnology
    • /
    • v.24 no.8
    • /
    • pp.1044-1050
    • /
    • 2014
  • Since there is no consensus about the most reliable assays to detect invasive aspergillosis from samples obtained by minimally invasive or noninvasive methods, we compared the efficacy of an enzyme-linked immunosorbent assay (ELISA) for galactomannan (GM) detection and quantitative real-time PCR assay (qRT-PCR) for the diagnosis of invasive pulmonary aspergillosis. Neutropenic, male Sprague-Dawley rats (specific pathogen free; 8 weeks old; weight, $200{\pm}20g$) were immunosuppressed with cyclophosphamide and infected with Aspergillus fumigatus intratracheally. Tissue and whole blood samples were harvested on days 1, 3, 5, and 7 post-infection and examined with GM ELISA and qRT-PCR. The A. fumigatus DNA detection sequence was detected in the following number of samples from 12 immunosuppressed, infected rats examined on the scheduled days: day 1 (0/12), day 3 (0/12), day 5 (6/12), and day 7 (8/12) post-infection. The sensitivity and specificity of the qRT-PCR assay was 29.2% and 100%, respectively. Receiver operating characteristic curve (ROC) analysis indicated a Ct (cycle threshold) cut-off value of 15.35, and the area under the curve (AUC) was 0.627. The GM assay detected antigen in sera obtained on day 1 (5/12), day 3 (9/12), day 5 (12/12), and day 7 (12/12) post-infection, and thus had a sensitivity of 79.2% and a specificity of 100%. The ROC of the GM assay indicated that the optimal Ct cut-off value was 1.40 (AUC, 0.919). The GM assay was more sensitive than the qRT-PCR assay in diagnosing invasive pulmonary aspergillosis in rats.

Common Fixed Point Theorems in Probabllistic Metric Spaces and Extension to Uniform Spaces

  • Singh, S.L.;Pant, B.D.
    • Honam Mathematical Journal
    • /
    • v.6 no.1
    • /
    • pp.1-12
    • /
    • 1984
  • Let(X, $\Im$) be a probabilistic metric space with a t-norm. Common fixed point theorems and convergence theorems generalizing the results of Ćirić, Fisher, Sehgal, Istrătescu-Săcuiu and others are proved for three mappings P,S,T on X satisfying $F_{Pu, Pv}(qx){\geq}min\left{F_{Su,Tv}(x),F_{Pu,Su}(x),F_{Pv,Tv}(x),F_{Pu,Tv}(2x),F_{Pv,Su}(2x)\right}$ for every $u, v {\in}X$, all x>0 and some $q{\in}(0, 1)$. One of the main results is extended to uniform spaces. Mathematics Subject Classification (1980): 54H25.

  • PDF

Thermal Properties and Sound-Damping Characteristics of Polyurethane Nanocomposite Foams (폴리우레탄 나노복합 발포체의 열적 성질 및 흡음 특성)

  • Lee, Jun Mo;Ha, Chang Sik
    • Journal of Adhesion and Interface
    • /
    • v.11 no.1
    • /
    • pp.3-8
    • /
    • 2010
  • Thermal properties, flame retardant property, and sound-damping properties of polyurethane (PU) nanocomposite foams prepared with oligomeric 1,2-propanediol isobutyl polyhedral silsesquioxane (POSS) were investigated. It was found that the PU nanocomposite foams showed good sound-damping performances comparing to the PU foams without POSS.

Synthesis and photoluminescence of polyurethane containing confined phenylenevinylene segment (주쇄에 Phenylenevinylene를 가진 PU-PV의 합성과 PL)

  • Lee, Mun-Hag;Yang, Jong-Heon;Chung, Su-Tae;Son, Se-Mo;Kim, Sung-Bin
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • 2002.07b
    • /
    • pp.1016-1018
    • /
    • 2002
  • Poly[bis (3,5-di-t-butyl-1,2-phenylene-1,2-thenylene)-1,4-phenylene-bis(11-oxyundecanylphenyl urethane)] (PV-PU) consisting of alternating a confined phenylenevinylene and a nonconjugated urethane segment in the main chain was synthesized by multistep, photoluminescence of PV-PU is emitted in the blue region with a maximum intensity at about 337 nm.

  • PDF

Preliminary Study on the MR Temperature Mapping using Center Array-Sequencing Phase Unwrapping Algorithm (Center Array-Sequencing 위상펼침 기법의 MR 온도영상 적용에 관한 기초연구)

  • Tan, Kee Chin;Kim, Tae-Hyung;Chun, Song-I;Han, Yong-Hee;Choi, Ki-Seung;Lee, Kwang-Sig;Jun, Jae-Ryang;Eun, Choong-Ki;Mun, Chi-Woong
    • Investigative Magnetic Resonance Imaging
    • /
    • v.12 no.2
    • /
    • pp.131-141
    • /
    • 2008
  • Purpose : To investigate the feasibility and accuracy of Proton Resonance Frequency (PRF) shift based magnetic resonance (MR) temperature mapping utilizing the self-developed center array-sequencing phase unwrapping (PU) method for non-invasive temperature monitoring. Materials and Methods : The computer simulation was done on the PU algorithm for performance evaluation before further application to MR thermometry. The MR experiments were conducted in two approaches namely PU experiment, and temperature mapping experiment based on the PU technique with all the image postprocessing implemented in MATLAB. A 1.5T MR scanner employing a knee coil with $T2^*$ GRE (Gradient Recalled Echo) pulse sequence were used throughout the experiments. Various subjects such as water phantom, orange, and agarose gel phantom were used for the assessment of the self-developed PU algorithm. The MR temperature mapping experiment was initially attempted on the agarose gel phantom only with the application of a custom-made thermoregulating water pump as the heating source. Heat was generated to the phantom via hot water circulation whilst temperature variation was observed with T-type thermocouple. The PU program was implemented on the reconstructed wrapped phase images prior to map the temperature distribution of subjects. As the temperature change is directly proportional to the phase difference map, the absolute temperature could be estimated from the summation of the computed temperature difference with the measured ambient temperature of subjects. Results : The PU technique successfully recovered and removed the phase wrapping artifacts on MR phase images with various subjects by producing a smooth and continuous phase map thus producing a more reliable temperature map. Conclusion : This work presented a rapid, and robust self-developed center array-sequencing PU algorithm feasible for the application of MR temperature mapping according to the PRF phase shift property.

  • PDF

Development of self-sealing waterproof materials using GRT powder (폐타이어 분말을 이용한 자체보수성 방수재 개발)

  • Lee Dong-Min;Choi Joong-So
    • Resources Recycling
    • /
    • v.14 no.4 s.66
    • /
    • pp.22-33
    • /
    • 2005
  • Four sheet-shaped and one soft-shaped self-sealing waterproof materials were prepared to recycle some GRT(Ground Rubber Tires). Their physical properties were tested to consider characteristics of them. The self-sealing waterproof materials were consisted of GRT/super absorbent polymer(SAP)/binder and mold by a hot press after mixing with a batch-typed internal mixer. The average size of GRT particles was -40 mesh, SAPs were commercial GE-500F and poly(AM-SAS-AA) prepared in this work. Binders were PU. EVA, LDPE, SBR, and poly(2-EHA). And PU film was attached to improve the properties of waterproof materials. Characteristics of self-sealing waterproof materials consisted of by GRT/GE-500F/EV-600/PU film and GRT/GE-500F/SBR(vulcanization)/PU film among the developed self-sealing waterproof materials were similar to the commercial products. And properties of the soft-shaped self-sealing waterproof materials consisted of by GRT/GE-500F/Po1y(2-EHA) and CRT/Poly(AM-SAS-AA)/poly(2-EHA) were improved within from four times to twenty times compared to the one oi the commercial products.

The Effect of Mobile Fashion Shopping Characteristics on Consumer's Purchase Intention - Applying the Technology Acceptance Model - (모바일 패션 쇼핑 특성이 소비자의 구매의도에 미치는 영향 - 기술수용모델(Technology Acceptance Model)을 적용 -)

  • Chae, Jin Mie
    • Fashion & Textile Research Journal
    • /
    • v.18 no.1
    • /
    • pp.38-47
    • /
    • 2016
  • This research analyzes the influence of mobile commerce characteristics on consumer's purchase intention using a theoretical Technology Acceptance Model (TAM) constructed on previous studies and a review of the literature to explain the effect of mobile fashion shopping characteristics on consumer's purchase intention. In constructing structural equation model, Mobile commerce characteristics variables such as 'security', 'enjoyment', and 'personalization' were selected as external variables affecting TAM. A questionnaire was distributed to consumers in their 20's-30's who had purchased fashion products using a mobile shopping channel. Statistical methods of confirmatory factor analysis, correlation, and covariance structural analysis using Amos 19.0 package were employed for the analysis of 453 effective data responses. The results were as follows. First, extended TAM was shown be the appropriate model to explain the influence of mobile commerce characteristics on consumer's purchase intention in mobile fashion shopping. Second, 'security' had a significant positive influence on perceived usefulness (PU), however it affected perceived ease of use (PEOU) negatively. Third, 'enjoyment' had a significant influence only on PEOU, while 'personalization' was found to affect both PEOU and PU significantly. Fourth, PEOU affected PU significantly. Finally, both PEOU and PU had a significant influence on consumer's purchase intention.

Implantation of Small Artery Vessel from Blends PCL/PU with and without Anti-thrombus

  • Hiep, Nguyen Thi;Lee, Seong-Jin;Min, Young-Ki;Yang, Hun-Mo;Song, Ho-Yeon;Lee, Byong-Taek
    • Proceedings of the Materials Research Society of Korea Conference
    • /
    • 2010.05a
    • /
    • pp.45.1-45.1
    • /
    • 2010
  • In this experiment, artificial blood vessel was fabricated from electro-spun PU/PCL. To assist with endothelial growth, PU/PCL surface was coated with the RGD peptide. To prevent a clot of blood, anti-thrombus agent was loaded to the fibrous mat and values were reflected through FT-IR data. In vitro study, SEM and MTT data showed that the component was of excellent biocompatibility and cell proliferation. In in vivo study, the artificial blood vessel was implanted in a dog's artery. The results of the CT scan, ultrasound and H&E staining showed that artificial blood vessel was excellent for artery replacement applications.

  • PDF

A comparative study of the past and present locations of Cui Pu's "Piaohailu" (崔溥 《漂海錄》 经由地点古今对比研究)

  • Choi, Changwon
    • Industry Promotion Research
    • /
    • v.8 no.1
    • /
    • pp.143-150
    • /
    • 2023
  • Cui Pu Korea period official, 1487 AD to Jeju Island to perform official duties, after the death of his father, in 1488 leap on the third day of the first month home, unfortunately encountered a storm on the way, and drifting in the sea nearly half a month later, finally landed in the "Datang state Zhejiang Taizhou Prefecture near the Hai county border" (now Sanmen county). Cui Pu traveled overland from Taizhou to Hangzhou, then via Hangzhou, by boat along the Beijing-Hangzhou Grand Canal to Beijing, and then by land from Beijing through Shanhaiguan Pass, through the Yalu River back to his motherland. We have pieced together the distance he traveled, the current situation of the places he passed through. He also hopes to make a new record of the changes of these sites by revisiting the important sites he has walked. This study explores Cui Pu's footprints and reviews the history by comparing the ancient and modern places he passed through.

Electrodeposition of some Alpha-Emitting Nuclides and its Isotope Determination by Alpha Spectrometry (몇가지 알파입자 방출 핵종의 전해석출 및 알파 스펙트럼 측정에 의한 그의 동위원소 정량)

  • Key-Suck Jung;In-Suck Suh
    • Journal of the Korean Chemical Society
    • /
    • v.27 no.4
    • /
    • pp.279-286
    • /
    • 1983
  • An apparatus was made for the electrodeposition of alpha emitting actinide nuclides, $^{207}Bi$ and $^{210}Po$. The electrodeposition was made on a polished stainless steel plate cathode. The anode was made of platinum wire and to stir the solution. With the ammonium chloride as electrolyte initial pH = 4, chloride concentration = 0.6M and solution volume = 15ml, a current of 1.5 ampere(current density = 0.59A/$cm^2$) was flowed for 100 minutes for the quantitative recovery of electrodeposition and on average recovery of 98.3% was obtained within ${\pm}$0.7% uncertainty. Alpha spectrometry of the electrodeposited sample showed alpha peaks from $^{210}Po, ^{234}U$ and $^{239}Pu$ having energy resolution (FWHM) of 18.3, 21.8 and 36.0 keV respectively. The electrodeposition and alpha spectrometry for a natural uranium sample of domestic origin gave $^{238}U : ^{234}U = 1 : 6.1{\times}10^{-5}$ and for a neutron-irradiated uranium sample did $^{238}U : ^{239}Pu : ^{241}Am = 100 : 0.0263 : 5.20{times}10^{-5}$. The result of $^{238}U$ determination in the irradiated sample by electrodeposition-alpha spectrometry was in accord within ${\pm}1.6%$ of relative error with the results of solid fluorimetry and mass spectrometry. For $^{239}Pu$ the result of electrodeposition-alpha spectrometry was in accord within ${\pm}$4.0% of relative error with the results of anion exchange separation and the thenoyltrifluoroacetone(TTA) extraction both followed by alpha spectrometries.

  • PDF