• Journal of Internet Computing and Services
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• v.25 no.2
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• pp.49-55
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• 2024

This paper proposes PredFeed Net, a neural network model that mimics the food distribution of fish farming experts. Unlike existing food distribution automation systems, PredFeed Net predicts food distribution by learning the food distribution patterns of experts. This has the advantage of being able to learn using only existing environmental data and food distribution records from food distribution experts, without the need to experiment by changing food distribution variables according to the environment in an actual aquarium. After completing training, PredFeed Net predicts the next food ration based on the current environment or fish condition. Prediction of feed ration is a necessary element for automating feed ration, and feed ration automation contributes to the development of modern fish farming such as smart aquaculture and aquaponics systems.

• Journal of IKEEE
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• v.18 no.3
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• pp.356-361
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• 2014

This paper proposes hardware architecture of HEVC (high efficiency video coding) CABAC (context-based adaptive binary arithmetic coding) binarizer. The proposed binarizer was designed and implemented as an independent module that can be integrated into HEVC CABAC encoder. It generates each bin string of each syntax element in a single cycle. It consists of controller module, TU (truncated unary binarization) module, TR (truncated Rice binarization) module, FL (fixed length binarization) module, EGK (k-th order exp-Golomb coding) module, CALR (coeff_abs_level_remaining) module, QP Delta (cu_qp_delta_abs) module, Intra Pred (intra_chroma_pred_mode) module, Inter Pred (inter_pred_idc) module, and Part Mode (part_mode) module. The proposed binarizer was designed in Verilog HDL, and it was implemented in 45 nm technology. Its operating speed, gate count, and power consumption are 200 MHz, 1,678 gates, and 50 uW, respectively.

• Proceedings of the Korean Information Science Society Conference
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• 2004.04b
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• pp.280-282
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• 2004

염기서열의 분석이 유전체에 대한 연구를 가능하게 해 줄 수 있다는 것이 밝혀짐에 따라 다양한 생명체에 대한 유전체 염기서열 분석 도구의 개발이 활발히 진행되었다. 이러한 유전자 예측 도구들은 고유의 단순 텍스트 형식으로 결과를 제공하므로 사용자는 결과를 분석하고 통계정보를 산출하는데 많은 노력이 필요하다. 본 논문에서는 유전자 예측결과를 보다 효율적으로 표현하고 분석하기 위한 XML 기반의 분석도구를 개발하였다. 개발된 시스템은 유전자 예측결과를 효과적으로 표현하는 GenStructML, 이 정보를 분석한 GenPredML과 PredAccuracyML로 구성되어 있다. GenPredML과 PredAccuracyML은 GenStructML에 대하여 뉴클레오티드 수준(nucleotide level), 엑손 수준(exon level) 그리고 신호 수준(signal level)에서의 예측 정확도(Accuracy)를 계산하고 Genbank의 정보와 비교하여 통계정보를 산출함으로써 보다 자세한 정보를 제공한다.

• Journal of the Korean Chemical Society
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• v.57 no.6
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• pp.744-754
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• 2013

Quantitative structure-activity relationship (QSAR) analysis for recently synthesized imidazole-(benz)azole and imidazole - piperazine derivatives was studied for their anticancer activities against breast (MCF-7) cell lines. The statistically significant 2D-QSAR models ($r^2=0.8901$; $q^2=0.8130$; F test = 36.4635; $r^2$ se = 0.1696; $q^2$ se = 0.12212; pred_$r^2=0.4229$; pred_$r^2$ se = 0.4606 and $r^2=0.8763$; $q^2=0.7617$; F test = 31.8737; $r^2$ se = 0.1951; $q^2$ se = 0.2708; pred_$r^2=0.4386$; pred_$r^2$ se = 0.3950) were developed using molecular design suite (VLifeMDS 4.2). The study was performed with 18 compounds (data set) using random selection and manual selection methods used for the division of the data set into training and test set. Multiple linear regression (MLR) methodology with stepwise (SW) forward-backward variable selection method was used for building the QSAR models. The results of the 2D-QSAR models were further compared with 3D-QSAR models generated by kNN-MFA, (k-Nearest Neighbor Molecular Field Analysis) investigating the substitutional requirements for the favorable anticancer activity. The results derived may be useful in further designing novel imidazole-(benz)azole and imidazole-piperazine derivatives against breast (MCF-7) cell lines prior to synthesis.

• The Journal of Korean Physical Therapy
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• v.24 no.5
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• pp.355-361
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• 2012

Purpose: The purpose of this study was to evaluate the effectiveness of pulmonary rehabilitation on lung function and fatigue in persons with chronic obstructive pulmonary disease (COPD). Methods: Thirty one persons with COPD participated in this study. Four groups were allocated as follows: experimental group 1 (under 10 years of the post-disease period), control group 1 (under 10 years of the post-disease period), experimental group 2 (over 10 years of the post-disease period), and control group 2 (over 10 years of the post-disease period). Results: Forced expired volume in one second (FEV1) % pred and lactic acid showed improvement in experimental group 1 and experimental group 2 after training. Control group 1 and control group 2 did not show improvement of FEV1% pred and lactic acid after training. However, FEV1% pred and lactic acid in experimental group 1 were not significantly different, compared with the experimental group. Conclusion: Results of our study suggest that implementation of a pulmonary rehabilitation program resulted in improvement of lung function and fatigue in persons with COPD not related to the post-disease period.

• Proceedings of the Korean Society for Language and Information Conference
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• 2007.11a
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• pp.375-384
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• 2007

This paper describes a method for automatic acquisition of wide-coverage treebank-based deep linguistic resources for Japanese, as part of a project on treebank-based induction of multilingual resources in the framework of Lexical-Functional Grammar (LFG). We automatically annotate LFG f-structure functional equations (i.e. labelled dependencies) to the Kyoto Text Corpus version 4.0 (KTC4) (Kurohashi and Nagao 1997) and the output of of Kurohashi-Nagao Parser (KNP) (Kurohashi and Nagao 1998), a dependency parser for Japanese. The original KTC4 and KNP provide unlabelled dependencies. Our method also includes zero pronoun identification. The performance of the f-structure annotation algorithm with zero-pronoun identification for KTC4 is evaluated against a manually-corrected Gold Standard of 500 sentences randomly chosen from KTC4 and results in a pred-only dependency f-score of 94.72%. The parsing experiments on KNP output yield a pred-only dependency f-score of 82.08%.

• The Korean Journal of Physiology and Pharmacology
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• v.17 no.6
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• pp.517-523
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• 2013

Naphthyridine compounds are important, because they exhibit various biological activities including anticancer, antimicrobial, and anti-inflammatory activity. Some naphthyridines have antimitotic effects or demonstrate anticancer activity by inhibiting topoisomerase II. These compounds have been investigated as potential anticancer agents, and several compounds are now part of clinical trials. A series of naphthyridine derivatives were evaluated for their in vitro cytotoxic activities against human cervical cancer (HeLa), leukemia (HL-60), and prostate cancer (PC-3) cell lines using an MTT assay. Some compounds (14, 15, and 16) were more potent than colchicine against all three human cancer cell lines and compound (16) demonstrated potency with $IC_{50}$ values of 0.7, 0.1, and $5.1{\mu}M$, respectively. Comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) were used for quantitative structure-activity relationship (QSAR) molecular modeling of these compounds. We obtained accurate and predictive three-dimensional QSAR (3D-QSAR) models as indicated by the high PLS parameters of the HeLa ($q^2$, 0.857; $r^2$, 0.984; $r^2\;_{pred}$, 0.966), HL-60 ($q^2$, 0.777; $q^2$, 0.937; $r^2\;_{pred}$, 0.913), and PC-3 ($q^2$, 0.702; $q^2$, 0.983; $r^2\;_{pred}$, 0.974) cell lines. The 3D-QSAR contour maps suggested that the C-1 NH and C-4 carbonyl group of the naphthyridine ring and the C-2 naphthyl ring were important for cytotoxicity in all three human cancer cell lines.

• The Korean Journal of Pesticide Science
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• v.9 no.4
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• pp.279-286
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• 2005

The herbicidal activities against pre-emergence barnyard grass (Echinochloa crus-galli) by a series of new 2-(4-(6-chloro-2-benzoxazolyloxy)phenoxy)-N-phenylpopionamide derivatives as substrate molecule were studied using molecular holographic (H) quantitative structure activity relationships (HQSAR) methodology. From the based on the findings, the higher herbicidal active compounds are predicted by the derived HQSAR model. The best HQSAR model (VI-1) was derived from fragment distinction combination of atoms/bonds in fragment size, $7{\sim}10$bin. The herbicidal activities from atomic contribution maps showed that the activity will be able to increased according to the R-substituents variation of the N-phenyl ring and change of 6-chloro-2-benzoxazolyloxy group. Based on the results, the statistical results of the best HQSAR model (VI-1) exhibited the best pedictability and fitness for the herbicidal activities based on the cross-validated value ($q^2=0.646$) and non cross-validated value ($r^2_{ncv.}=0.917$), respectively. From the graphical analyses of atomic contribution maps, it was revealed that the lowest herbicidal activitics depends upon the 4-(6-chloro-2-benzoxazolyloxy)phenoxy group ($pred.pI_{50}=-3.20$). Particularly, the R=4-fluoro, X=isobutoxy substituent (P2) of (X)-phenoxy-N-(R)-phenylpropionamide derivative is predicted as the highest active compound ($pred.pI_{50}=9.12$).

• Journal of the Korean Institute of Intelligent Systems
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• v.16 no.4
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• pp.416-422
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• 2006

Most of the existing statistical models of software manpower profile are based on the assumptions of the usage and development process. Therefore, there is no universally applicable estimation and prediction model. To develop a prediction model, this paper suggests the predictive filter as a prediction model for software manpower profile. Firs of all, we investigate the software manpower profile and we suggest the input-output of predictive filter and method for parameter determination. Then, its usefulness is empirically verified by analyzing the actual data obtained from the software projects. Based on the average relative prediction error and Pred(0.25), the suggested predictive filter is compared with other well-known statistical estimation models. As a result, the predictive filter generally has a simple structure and on the other hand, it adapts the software manpower profile very well.

• Tuberculosis and Respiratory Diseases
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• v.44 no.5
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• pp.1030-1039
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• 1997

Background : Impulse Oscillometry is a noninvasive and effort-independent test used to characterize the mechanical impedance of the respiratory system. The clinical potential of the IOS is rapid and demands only passive cooperation which makes it especially appealing for children, for epidemiologic surveys and for conditions in which quiet breathig instead of forced expiratory maneuvers are preferred. However, several studies have shown conflicting results that the role of IOS about detection of smoking induced small airway diseases or early airway obstruction Methods : Study was to evaluate the clinical ability of the IOS to detect about smoking induced early airway obstruction in persons with normal spirometry test. Respiratory asymptomatic study groups were formed that one is non-smoking group, another is smoking group. Results : The parameters of spirometry were not significantly differences between non-smoking group and smoking group. Among the parameters of IOS, total resistance(non-smoking group : smoking group=$2.22{\pm}1.20$ : $2.58{\pm}1.71$), peripheral resistance($1.25{\pm}0.62$ : $1.47{\pm}0.10$), bronchial compliance($0.44{\pm}0.12$ : $0.47{\pm}0.16$) were not statistically significant different (p<0.05), but central resistance and lung compliance were not statistically significant different (unit ; resistance=hPa/l/s, compliance=l/hPa). Resistance(Rrs) was not statistically significant different with changes of frequences(5, 10, 15, 20, 25, 30, 35Hz), but Reactance(Xrs) was statistically significant different with low frequences that X5(non-smoking group : smoking group=$-0.62{\pm}0.28$ : $-0.76{\pm}0.48$, p<0.001) and X10($-0.06{\pm}0.19$ : $-0.15{\pm}0.33$, p<0.013) (unit; hPall/s, $hPa{\cong}cmH_2O$). Conclusion : Impulse oocillometer(IOS) is clinically available method to detect about smoking induced early airway obstruction. And clinically potential parameters of IOS were considers that total resistance, peripheral resistance, bronchial resistance, and reactance of low frequency at 5Hz, 10Hz.